• Korean Journal of Veterinary Research
• /
• v.52 no.2
• /
• pp.69-74
• /
• 2012

The analytical method of trace toxic metals in livestock products was confirmed and validated through certified reference material (CRM) and the international proficiency tests. There are some difficulties to determine low levels of toxic metals in livestock products because of interferences due to the matrix. The recoveries of CRM (NIST 1577c) ranged from 73.9 to 119% for lead and from 86.4 to 111% for cadmium in bovine liver. The international proficiency tests were carried out with the milk powder and cocoa powder samples including metals provided by Food Analysis Performance Assessment Scheme (FAPAS$^{(R)}$, UK). The test samples were prepared by microwave digestion using solution of $HNO_3:H_2O_2:H_2O$ (v/v/v = 5 : 2 : 4) and analyzed by ICP/MS. The analytical result of cadmium in milk powder was $121{\mu}g/kg$ with -0.3 of the z-score compared to the assigned value of $131{\mu}g/kg$ by FAPAS$^{(R)}$. The analytical results of lead and cadmium in cocoa powder were $29.2{\mu}g/kg$ and $97.6{\mu}g/kg$, respectively, which satisfied the assigned values of $34.2{\mu}g/kg$ for lead and $126{\mu}g/kg$ for cadmium by FAPAS$^{(R)}$. It is verified that the analytical method is accurate and reliable to determine trace lead and cadmium in livestock products by microwave digestion and ICP/MS.

• Structural Engineering and Mechanics
• /
• v.24 no.6
• /
• pp.647-664
• /
• 2006

In this study, an improved finite element formulation with a scheme of solution for the large deflection analysis of inextensible prismatic and nonprismatic slender beams is developed. For this purpose, a three-noded Lagrangian beam-element with two dependent degrees of freedom per node (i.e., the vertical displacement, y, and the actual slope, $dy/ds=sin{\theta}$, where s is the curved coordinate along the deflected beam) is used to derive the element stiffness matrix. The element stiffness matrix in the global xy-coordinate system is achieved by means of coordinate transformation of a highly nonlinear ($6{\times}6$) element matrix in the local sy-coordinate. Because of bending with large curvature, highly nonlinear expressions are developed within the global stiffness matrix. To achieve the solution after specifying the proper loading and boundary conditions, an iterative quasi-linearization technique with successive corrections are employed considering these nonlinear expressions to remain constant during all iterations of the solution. In order to verify the validity and the accuracy of this study, the vertical and the horizontal displacements of prismatic and nonprismatic beams subjected to various cases of loading and boundary conditions are evaluated and compared with analytic solutions and numerical results by available references and the results by ADINA, and excellent agreements were achieved. The main advantage of the present technique is that the solution is directly obtained, i.e., non-incremental approach, using few iterations (3 to 6 iterations) and without the need to split the stiffness matrix into elastic and geometric matrices.

• Structural Engineering and Mechanics
• /
• v.90 no.1
• /
• pp.19-26
• /
• 2024

In recent years, an increasing number of experimental studies have shown that the practical application of mature active control systems requires consideration of robustness criteria in the design process, including the reduction of tracking errors, operational resistance to external disturbances, and measurement noise, as well as robustness and stability. Good uncertainty prediction is thus proposed to solve problems caused by poor parameter selection and to remove the effects of dynamic coupling between degrees of freedom (DOF) in nonlinear systems. To overcome the stability problem, this study develops an advanced adaptive predictive fuzzy controller, which not only solves the programming problem of determining system stability but also uses the law of linear matrix inequality (LMI) to modify the fuzzy problem. The following parameters are used to manipulate the fuzzy controller of the robotic system to improve its control performance. The simulations for system uncertainty in the controller design emphasized the use of acceleration feedback for practical reasons. The simulation results also show that the proposed H∞ controller has excellent performance and reliability, and the effectiveness of the LMI-based method is also recognized. Therefore, this dynamic control method is suitable for seismic protection of civil buildings. The objectives of this document are access to adequate, safe, and affordable housing and basic services, promotion of inclusive and sustainable urbanization, implementation of sustainable disaster-resilient construction, sustainable planning, and sustainable management of human settlements. Simulation results of linear and non-linear structures demonstrate the ability of this method to identify structures and their changes due to damage. Therefore, with the continuous development of artificial intelligence and fuzzy theory, it seems that this goal will be achieved in the near future.

• Food Science and Preservation
• /
• v.30 no.1
• /
• pp.109-121
• /
• 2023

This study was conducted to evaluate vitamin D intake of Koreans in a total diet study (TDS) and to determine the effect of irradiation on vitamin D synthesis in mushrooms. For analysis, sample were saponified and extracted with hexane, and vitamin D was quantified by liquid chromatography-tandem mass spectrometry (LC-MS/MS). Based on the validation results, the recovery of the National Institute of Standards and Technology (NIST) standard reference sample (SRM) 1849a was 96.7% and the z-score of -1.6 was obtained by the Food Analysis Performance Assessment Scheme (FAPAS) proficiency test (PT) 21115. Vitamin D₂ was not detected in any samples, and the highest level of vitamin D₃ was detected in mackerel and anchovies ranging from 24.2 to 120.2 ㎍/kg. The mean daily intake of vitamin D was 0.99 ㎍/day, as estimated from the vitamin D contents of the analyzed foods and their corresponding intake. The adequate intake (AI) of vitamin D based on the Dietary reference intakes for Koreans provided by the Ministry of Health and Welfare is 5-15 ㎍/day for Koreans aged 6 to 75 years. Compared with this AI, vitamin D intake of Koreans estimated in this study was inadequate. For that, the increased vitamin D content in ultraviolet (UV)/sun light irradiated mushrooms warrants further research to increase vitamin D intake of Koreans through diet.

• The korean journal of orthodontics
• /
• v.25 no.6 s.53
• /
• pp.675-688
• /
• 1995

The purposes of this study were:1) to determine the normal range of CR-CO discrepancy in normal occlusion group ; 2) to evaluate the changes of condylar position and craniofacial morphology between centric relation and centric occlusion before and after stabilization splint therapy in malocclusion group outside the normal range of CR-CO discrepancy. The normal occlusion group consisted of 80 subjects who had well-balanced faces and good occlusions with acceptable Class I molar relationship. They had not been treated orthodontically and had no signs or symptoms of temporomandibular joint dysfunction. 71 malocclusion patients enrolled for orthodontic treatment at the Department of Orthodontics, College of Dentistry, Chosun University comprised the malocclusion group, little variation of growth factor by the second molar eruption. They had CR-CO discrepancy beyond normal range and were subdivided into anterior-posteriorly -[25 Class I (0$\geq$4), and 24 Class III (ANB$\leq$0)] : vertically - [20 Normodivergentscy (30$\geq$34), and 18 Hypodivergency (SNGoMe$\leq$30)] ; and sexually - [26 Male and 45 Female]. For malocclusion group, stabilization splint with mutually protected type of occlusal scheme was applied for three months. Panadent articulators, Panadent condylar position indicator (CPI), and lateral headfilm were used to investigate the influence of stabilization splint on condylar position and craniofacial morphology. The results of this study were as follows. 1. The amounts of CR-CO discrepancy in normal occlusion were that the antero-Posterior component (${\bigtriangledown}X$) was $0.56\pm0.46mm$ (Male:$0.63\pm0.42mm$, Female:$0.49\pm0.50mm$) ; the supero-inferior component (${\bigtriangledown}Y$) was $-0.75\pm0.48mm$ (Male:$-0.76\pm0.52mm$, Female:-$0.73\pm0.43mm$) : and the transverse component (${\bigtriangledown}Z$) was $-0.33\pm0.28mm$ (Male : $-0.38\pm0.29mm$, Female:$-0.31\pm0.27mm$). 2. The condylar position was in normal range after stabilization splint therapy. 3. The mandible was always rotated infero-posteriorly after stabilization splint therapy. 4. Antero-posteriorly, Class III malocclusion responded very well to the stabilization splint therapy. 5. Vertically, Hyperdivergency responded very well to the stabilization splint therapy 6. Sexually, Male responded very well to the stabilization splint therapy.

• Journal of the Korean Society for Aeronautical & Space Sciences
• /
• v.38 no.10
• /
• pp.1038-1048
• /
• 2010

Radiation exposures of an astronaut during the space travels to the International Space Station(ISS) of the Soyuz and the Moon of the Apollo, were calculated considering the altitude, boarding time, period of stay, kinds of spaceships and space suits. The calculated radiation exposures decrease dramatically according to the thickness of the shielding by the wall of the spaceships and by the space suits. For the space travel to the ISS of Soyuz at Low Earth orbit, the thickness of the spaceship required to optimally reduce the radiation exposure is 3 cm. For the Extravehicle Mobility Unit(EMU) the exposures are minimized at 4 cm of the aluminized Mylar and 5 cm of the Demron, respectively. The aluminized Mylar showed better radiation shielding than the Demron which contains the high Z materials. The radiation exposures of an astronaut were $4.2\times10^{-6}$ Sv for the ISS travel and $4.3\times10^{-5}$ Sv for the Moon explore. The high concentration of the high energy proton flux at the surface of the Moon results in high radiation exposure. The calculation scheme and results of this study can be used in the design of the shielding performance of a spaceship and space suits.

• Journal of the Korean association of regional geographers
• /
• v.10 no.2
• /
• pp.313-340
• /
• 2004

Namhansan fortress of Kwangju in Kyonggi Province has remained a traumatic historical landscape of Manchu invasion in the year 1636. Skirted by the mountain fortress and on the ground of the uplifted flatland was the county seat which was relocated in 16Z7 from Kogol at the underneath ravine and later removed in 1917 to a crossroad place at the low-lying river plain. Once a secluded mountain village, Sungnaedong was at the outset planned as a county town of Kwangju, achieving thereafter a dramatic transformation from a small town of three hundred households into a nascent urban settlement of approximately six hundred households by the mid-18th century. The townscape of Sungnaedong features shrines, a second palace, a magistrate-commander's office, administrative buildings, and a periodic marketplace which were all decreed by the Neo-confucian template of the scheme of county seats. Townspeople managed to live on tilling tax-alleviated crop lands, trading merchandise, and selling their labor. Changing socio-economic situations led to the relocation of the administration center to the gateway village of Jumakri, which consequently heralded the decline of the mountain-fortress settlement of Sansungri at Namhansan.

• Proceedings of the Korean Radioactive Waste Society Conference
• /
• 2005.11a
• /
• pp.321-331
• /
• 2005

Recently. three-dimensional models have been used for aquatic dispersion of radioactive effluents in relation to nuclear power plant siting based on the Notice No. 2003-12 'Guideline for investigating and assessing hydrological and aquatic characteristics of nuclear facility site' of the Ministry of Science and Technology (MOST) in Korea. Several nuclear power plants have been under construction or planed. which are Shin-Korl Unit 1 and 2, Shin-Wolsong Unit 1 and 2, and Shln-Ulchin Unit 1 and 2. For assessing the aquatic dispersion of radionuclides released from the above nuclear power plants, it is necessary to know the coastal currents around sites which are affected by circulation of East Sea. In this study, a three dimensional hydrodynamic model for the circulation of the East Sea of Korea has been developed as the first Phase, which Is based on the RIAMOM. The model uses the primitive equation with hydrostatic approximation, and uses Arakawa-B grid system horizontally and Z-coordinate vertically. Model domain is $126.5^{\circ}E\;to\;142.5^{\circ}E$ of east longitude and $33^{\circ}N\;and\;52^{\circ}N$ of the north latitude. The space of the horizontal grid was $1/12^{\circ}$ to longitude and latitude direction and vortical level was divided to 20. This model uses Generalized Arakawa Scheme. Slant Advection, and Mode-Splitting Method. The input data were from JODC, KNFRDI, and ECMWF. The model ing results are in fairly good agreement with schematic patterns of the surface circulation in the East Sea The local current model and aquatic dispersion model of the coastal region will be developed as the second phase. The oceanic dispersion experiments will be also tarried out by using ARGO Drifter around a nuclear pelter plant site.

• Biomolecules & Therapeutics
• /
• v.21 no.1
• /
• pp.29-34
• /
• 2013

The tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) is a member of the tumor necrosis factor family of cytokines. TRAIL selectively induces apoptotic cell death in various tumors and cancer cells, but it has little or no toxicity in normal cells. Agonism of TRAIL receptors has been considered to be a valuable cancer-therapeutic strategy. However, more than 85% of primary tumors are resistant to TRAIL, emphasizing the importance of investigating how to overcome TRAIL resistance. In this report, we have found that nemadipine-A, a cell-permeable L-type calcium channel inhibitor, sensitizes TRAIL-resistant cancer cells to this ligand. Combination treatments using TRAIL with nemadipine-A synergistically induced both the caspase cascade and apoptotic cell death, which were blocked by a pan caspase inhibitor (zVAD) but not by autophagy or a necrosis inhibitor. We further found that nemadipine-A, either alone or in combination with TRAIL, notably reduced the expression of survivin, an inhibitor of the apoptosis protein (IAP) family of proteins. Depletion of survivin by small RNA interference (siRNA) resulted in increased cell death and caspase activation by TRAIL treatment. These results suggest that nemadipine-A potentiates TRAIL-induced apoptosis by down-regulation of survivin expression in TRAIL resistant cells. Thus, combination of TRAIL with nemadipine-A may serve a new therapeutic scheme for the treatment of TRAIL resistant cancer cells, suggesting that a detailed study of this combination would be useful.

• Korean Journal of Food Science and Technology
• /
• v.52 no.6
• /
• pp.580-586
• /
• 2020

Fishery resources have been widely consumed as protein- and vitamin-rich food sources in the Korean diet. However, information regarding their vitamin levels is extremely limited. In this study, trienzyme-Lactobacillus casei method was validated and used to determine the folate contents in fishery foods. The trienzyme-L. casei method for folate analysis showed excellent accuracy (85.2 to 95.3% recovery) and precision (repeatability 1.4% RSD and reproducibility 2.4% RSD). Folate contents of 20 fish foods (4 fish, 3 crustaceans, 3 sea algae, 3 cephalopods, 4 shellfish, and 3 others) ranged from 1.75 to 97.98 ㎍/100 g. Furthermore, we found that the folate content in seaweed fusiforme was the highest, followed by gulfweed (69.73 ㎍/100 g). Folate analysis using the trienzyme-L. casei method was determined excellent based on the z-score of -0.3 in the Food Analysis Performance Assessment Scheme test. Analytical and method validation data generated in this study could be used to update the national food composition table on vitamin B9 in Korean fishery resources.