• 제목/요약/키워드: Yun nan

검색결과 100건 처리시간 0.02초

A Basic Helix-Loop-Helix Transcription Factor Regulates Cell Elongation and Seed Germination

  • Kim, Jin-A;Yun, Ju;Lee, Minsun;Kim, Youn-Sung;Woo, Jae-Chang;Park, Chung-Mo
    • Molecules and Cells
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    • 제19권3호
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    • pp.334-341
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    • 2005
  • Plants are sessile and rely on a wide variety of growth hormones to adjust growth and development in response to internal and external stimuli. We have identified a gene, designated NAN, encoding a basic helix-loop-helix (bHLH) transcription factor that regulates cell elongation and seed germination in plants. NAN has an HLH motif in its C-terminal region but does not have any other discernible homologies to bHLH proteins. A bipartite nuclear localization signal is located close to the HLH motif. An Arabidopsis mutant, nan-1D, in which NAN is activated by the insertion of the 35S enhancer, exhibits growth retardation with short hypocotyls and curled leaves. It is also characterized by reduced seed germination and apical hook formation, symptomatic of GA deficiency or disrupted GA signaling. The phenotypic effects of nan-1D were increased by treatment with paclobutrazol (PAC), an inhibitor of gibberellic acid (GA) biosynthesis. NAN is constitutively expressed throughout the life cycle. Our observations indicate that NAN has a housekeeping role in plant growth and development, particularly in seed germination and cell elongation, and that it may modulate GA signaling.

Identification of Serum MicroRNA-21 as a Biomarker for Early Detection and Prognosis in Human Epithelial Ovarian Cancer

  • Xu, Yun-Zhao;Xi, Qing-Hua;Ge, Wen-Liang;Zhang, Xiao-Qian
    • Asian Pacific Journal of Cancer Prevention
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    • 제14권2호
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    • pp.1057-1060
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    • 2013
  • Recent investigations have confirmed up-regulation of serum miR-21 and its diagnostic and prognostic value in several human malignancies. In this study, we examined serum miR-21 levels in epithelial ovarian cancer (EOC) patients, and explored its association with clinicopathological factors and prognosis. The results showed significantly higher serum miR-21 levels in EOC patients than in healthy controls. In addition, increased serum miR-21 expression was correlated with advanced FIGO stage, high tumor grade, and shortened overall survival. These findings indicate that serum miR-21 may serve as a novel diagnostic and prognostic marker, and be used as a therapeutic target for the treatment of EOC.

이족(彝族)과 한족(漢族)의 문화접변(文化接變) 양상(樣相) 연구(硏究) - 운남성(雲南省) 이족(彝族)의 정신문화(精神文化)를 중심으로 (The study Yi-Zu and Han-Zu's moral culture. - with focus on the Yun-Nan's Yi-Zu moral culture)

  • 김덕삼
    • 비교문화연구
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    • 제26권
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    • pp.353-377
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    • 2012
  • This treatise studies on how ideology and value of Chinese minority race undergo change according to social, political transition that the Chinese minority race has experienced for a long time and I also have tried to elucidate how these kinds of their experiences have been effected upon their own life, even it is part of my basic subjects for my study. Hence I would give weigh to focus on contemplating process of the past and the present rather than predictive discussion of how their pursuing value will be transformed. For my ebullient study, I'm willing to make Yi-Zu's moral culture become axis of my treatise, and capitalize on not only how Han-Zu's ideological philosopies have been disseminated, but also how acculturation have been taken place in Yi-Zu's moral culture system. Yi-Zu has the longest history and the greatest their own population, even the largest residence of various Chinese minority races. And Yun-Nan is the historical place where not only various Chinese minority races have lived, but also acculturation between Chinese majority, Han-Zu and them have been begotten. Above all, I would delve into traditional religion to understand Yi-Zu's moral culture as was already mentioned that it is my axis of treatise. Furthermore, I deliberated on how Taoism have been infiltrated Yi-Zu's moral culture, also how Han-Zu's ideological philosophies have been permeated Yi-Zu's, and what is more how to help themselves still remained in Yi-Zu's. Through my such these efforts, I analyze the aspect of embracing of Han-Zu's moral culture by Yi-Zu's and some facts of vicissitudes about it.