• Title/Summary/Keyword: YoungChu

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Susceptibility for breast cancer in young patients with short rare minisatellite alleles of BORIS

  • Yoon, Se-Lyun;Kim, Dae-Cheol;Cho, Se-Heon;Lee, Sang-Yeop;Chu, In-Sun;Heo, Jeong-Hoon;Leem, Sun-Hee
    • BMB Reports
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    • v.43 no.10
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    • pp.698-703
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    • 2010
  • In this study, we characterized two blocks of minisatellites in the 5' upstream region of the BORIS gene (BORIS-MS1, -MS2). BORIS-MS2 was found to be polymorphic; therefore, this locus could be useful as a marker for DNA fingerprinting. We assessed the association between BORIS-MS2 and breast cancer by a case-control study with 428 controls and 793 breast cancers cases. Rare alleles in the younger group (age, <40) were associated with a statistically significant increased risk of breast cancer (odds ratio, 4.84; 95% confidence interval, 1.06-22.22; and P = 0.026). A statistically significant association between the short rare alleles and cancer was identified in the younger group (8.02; 1.01-63.83; P = 0.021). Kaplan-Meier estimates showed that poor prognosis was associated with patients who contained the rare alleles. Our data suggest that the short rare alleles of BORIS-MS2 could be used to identify the risk for breast cancer in young patients.

Fine Needle Aspiration Cytologic Findings of Fibromatosis Colli - A Report of Three Cases - (경부섬유종증의 세침흡인 세포소견 - 3예 보고 -)

  • Park, In-Suh;Kim, Lucia;Choi, Suk-Jin;Han, Jee-Young;Chu, Young-Chae;Choi, Sun-Geun;Kim, Joon-Mee
    • The Korean Journal of Cytopathology
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    • v.16 no.1
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    • pp.61-65
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    • 2005
  • Fibromatosis colli is a benign fibrous tissue proliferation of sternocleidomastoid muscle, which is usually observed during the first month of life, often associated with congenital torticollis. It should be differentiated from other neck masses in infants because the usual initial treatment of fibromatosis celli is conservative management and invasive therapy should be avoided. Fine needle aspiration cytology provides an excellent minimally invasive diagnostic way for evaluation of infantile neck masses. We describe three cases of fibromatosis colli diagnosed by fine needle aspiration cytology. All of them were younger than one month and presented as a neck mass. Clinical impressions were malignant tumors in two cases and fibromatosis colli in one case. Fine needle aspiration cytology revealed benign and mature fibroblasts and atrophic striated muscle fibers. The cytologic diagnosis was fibromatosis colli or benign fibous lesion.

Pathological and serological detection of bovine viral leukosis in a dairy farm in Jeonbuk province (유우농장에서 발생한 소바이러스성 백혈병의 병리학적 및 혈청학적 조사)

  • Jo Young-Suk;Jang Sae-Gun;Chu Keum-Suk;Choi Eun-Young;Chon Hee-Woong;Hong Jae-Hee;Lim Chae-Woong
    • Korean Journal of Veterinary Service
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    • v.29 no.2
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    • pp.89-96
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    • 2006
  • Bovine viral leukosis is a viral disease of cattle characterized by the development of tumors in the lymphatic tissue. A female Holstein, 3-year-old, was submitted for diagnosis at the Diagnostic laboratory, Chonbuk National University. Clinical sign of the affected animal showed emaciation, enlargement of superficial lymph node and mild diarrhea. Remarkable lesions were enlargement of many internal lymph nodes. Histopathology revealed excessive neoplastic lymphoid cells characteristic of BVL infection. Subsequently, serums from all cattle were collected and serological examination was done where a 85% seropositive rate was detected using ELISA test. ELISA method showed a comparatively 75% higher detection rate than the agar gel immunodiffusion (AGID) test (85% vs 40%). Serologically positive cattle were variably detected in all ages from under 1 year to over 6 year of age. Hematological examination consistently showed leukocytosis and a differential lymphocytosis of seropositive cattle. Detailed comparative pathological and serological data diagnosed the presence of bovine viral leukosis.

Solution-Processible Blue-Light-Emitting Polymers Based on Alkoxy-Substituted Poly(spirobifluorene)

  • Lee, Jeong-Ik;Chu, Hye-Yong;Oh, Ji-Young;Do, Lee-Mi;Lee, Hyo-Young;Zyung, Tae-Hyoung;Lee, Jae-Min;Shim, Hong-Ku
    • ETRI Journal
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    • v.27 no.2
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    • pp.181-187
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    • 2005
  • Alkoxy-substituted poly(spirobifluorene)s and their copolymers with a triphenylamine derivative have been synthesized by Ni(0)-mediated polymerization. The polymers were well soluble in common organic solvents. Pure blue-light emissions without the long wavelength emission of poly(fluorene)s have been observed in the fluorescence spectra of polymer thin films. The light emitting diodes with a device configuration of ITO/PEDT:PSS(30 nm)/polymer(60 nm)/LiF(1 nm)/Al(100 nm) have been fabricated. The electroluminescence spectra showed the blue emissions without the long wavelength emission as observed in the fluorescence spectra. The relatively poor electroluminescence quantum yield of the homopolymer (0.017% @ 20 $mA/cm^{2}$) with color coordinates of (0.16, 0.07) has been improved by the introduction of triphenylamine moiety, and the copolymer with derivative exhibited an electroluminescence quantum yield of 0.15 % at 20 $mA/cm^{2}$ with color coordinates of (0.16, 0.08). Moreover, the introduction of polar side chains to the spirobifluorene moiety enhanced the device performance and led to the quantum yields of 0.6 to 0.7 % at 20 $mA/cm^{2}$, although there was some expense of color purities.

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Enhanced Internal Quantum Efficiency and Light Extraction Efficiency of Light-emitting Diodes with Air-gap Photonic Crystal Structure Formed by Tungsten Nano-mask

  • Cho, Chu-Young;Hong, Sang-Hyun;Kim, Ki Seok;Jung, Gun-Young;Park, Seong-Ju
    • Bulletin of the Korean Chemical Society
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    • v.35 no.3
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    • pp.705-708
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    • 2014
  • We demonstrate the blue InGaN/GaN multiple quantum wells light-emitting diodes (LEDs) with an embedded air-gap photonic crystal (PC) which was fabricated by the lateral epitaxial overgrowth of GaN layer on the tungsten (W) nano-masks. The periodic air-gap PC was formed by the chemical reaction of hydrogen with GaN on the W nano-mask. The optical output power of LEDs with an air-gap PC was increased by 26% compared to LEDs without an air-gap PC. The enhanced optical output power was attributed to the improvement in internal quantum efficiency and light extraction efficiency by the air-gap PC embedded in GaN layer.

Low molecular amorphous spirobifluorene derivatives for blue electroluminescence

  • Lee, Hyo-Young;Oh, Ji-Young;Chu, Hye-Yong;Lee, Jeong-Ik;Kim, Seong-Hyun;Yang, Yong-Suk;Do, Lee-Mi;Zyung, Tae-Hyoung
    • 한국정보디스플레이학회:학술대회논문집
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    • 2001.08a
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    • pp.209-212
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    • 2001
  • We report the synthesis and characterization of new alkoxy substituted spirobifluorene derivatives. The spiro compounds having alkoxy hydrocarbon chains were readily soluble in common organic solvents, having improved film-forming properties and had a significantly reduced tendency to crystallize, resulting in increasing their service lifetime. The results of DSC showed that it was amorphous. The optical and electroluminescent spectra were characterized. Electroluminescence (EL) properties of three-layer light emitting diodes (LED) of $ITO/TPD/spirobifluorene/Alq_3/LiF/Al$ as the active layer were characterized. Blue emission peaking of the EL spectrum of the three-layer device at 402 nm and a luminance of 3,125 $cd/m^2$ were achieved at a drive voltage 12.8 V. The luminous efficiency was obtained to be 1.7 lm/W. The color coordinate in CIE chromaticity is (0.16, 0.09), which is in a pure blue region. The external quantum efficiency was obtained to be 2.0%. The results indicate that the spirobifluorene compounds having alkoxy hydrocarbon chains are strongly potential blue emitters for LED applications.

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High-yield synthesis of thin multiwalled carbon nanotubes and their field emission characteristics

  • Jeong, Hee-Jin;Song, Young-Il;Choi, Ha-Kyu;Kim, Gil-Yong;Yu, Tong;Lim, Seong-Chu;Lee, Young-Hee
    • 한국정보디스플레이학회:학술대회논문집
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    • 2005.07b
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    • pp.1443-1446
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    • 2005
  • We have synthesized thin multi-walled carbon nanotubes (t-MWCNTs) using a catalytic chemical vapor deposition (CCVD) method with FeMoMgO catalyst. The number of tube walls were 2 ${\sim}$ 6 with the corresponding diameters of 3 ${\sim}$ 6 nm. We obtained high production yield of over 3000 wt% compared to the weight of the supplied catalyst. These t-MWCNTs revealed the intermediate structural characteristics between single- and multi-walled carbon nanotubes (SWCNTs and MWCNTs). We have also characterized the field emission properties such as turn-on field and emission current, and current degradation from these t-MWCNTs together with SWCNTs and MWCNTs.

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A Case of Ruptured Mycotic Hepatic Artery Aneurysm Successfully Treated Using Arterial Embolization

  • Kim, Gi-Ae;Lee, Han-Chu;Jin, Young-Joo;Yang, Jee-Eun;Lee, Min-Jung;Park, Ji-Hyun;Lee, Bo-Young
    • Journal of Yeungnam Medical Science
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    • v.29 no.1
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    • pp.24-27
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    • 2012
  • Mycotic hepatic artery aneurysms (HAAs) have become very rare due to antibiotics. Untreated, they have a high possibility of rupture and mortality. In this paper, on the case of a 67-year-old male who had severe right-upper-quadrant abdominal pain and a history of infective endocarditis is reported. The computed tomography (CT) and arterial angiography findings led to a diagnosis of a ruptured mycotic HAA. The CT showed an HAA and the formation of an intrahepatic hematoma caused by aneurysmal rupture. The arterial angiography showed a mycotic HAA that arose from the right posterior hepatic artery. Percutaneous transcatheter arterial embolization was used to successfully treat the HAA. Since then, the patient has been doing well, without symptoms.

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