• Genomics & Informatics
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• 제7권2호
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• pp.131-135
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• 2009

Domains are the building blocks of proteins. Exon shuffling is an important mechanism accounting for combination of a limited repertoire of protein domains in the evolution of multicellular species. A relative excess of domains encoded by symmetric exons in metazoan phyla has been presented as evidence of exon shuffling, and symmetric domains can be divided into old and new domains by determining the ages of the domains. In this report, we compare the spread, versatility, and subcellular localization of old and new domains by analyzing eight metazoan genomes and their respective annotated proteomes. We found that new domains have been expanding as multicellular organisms evolved, and this expansion was principally because of increases in class 1-1 domains amongst several classes of domain families. We also found that younger domains have been expanding in membranes and secreted proteins along with multi-cellular organism evolution. In contrast, old domains are located mainly in nuclear and cytoplasmic proteins. We conclude that the increasing mobility and versatility of new domains, in contrast to old domains, plays a significant role in metazoan evolution, facilitating the creation of secreted and transmembrane multidomain proteins unique to metazoa.

• 한국보건간호학회지
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• 제28권3호
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• pp.419-431
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• 2014

Purpose: The aim of this study was to understand the determinants of health-related quality of life (HRQOL) according to age groups in vulnerable elderly women. Methods: We conducted a cross-sectional study with 1,533 elderly women beneficiaries of the visiting health care program in Seoul. The participants were divided into three age groups: the young-old (n=753, 65-74 years), old-old (n=602, 75-84 years), and oldest-old (n=178, 85 years or older) groups. HRQOL was measured using the SF-8 questionnaire. Results: HRQOL was found to be worse in the oldest-old group (p=.007). Factors associated with HRQOL differ by age groups. In the young-old and old-old groups, higher HRQOL showed significant correlation with a higher level of self-rated health (SRH) and a lower level of depression, instrumental activities of daily living (IADL) dependence, and the number of chronic diseases. In addition, higher HRQOL was observed for elderly living alone than for those living with family. In the oldest group, higher HRQOL showed significant correlation with a lower level of depression, activities of daily living (ADL) dependence, and a higher level of SRH. Conclusions: In age specific groups, lower levels of HRQOL were observed for the oldest-old group than for the other age groups. Age group-specific nursing strategies may be required for improving HRQOL levels of vulnerable elderly women.

• Journal of Korean Biological Nursing Science
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• 제13권1호
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• pp.53-60
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• 2011

Purpose: The purpose of the present study was to investigate the prevalence and lifestyle factors related to the metabolic syndrome in Korean elderly. Methods: A total number of 122 elderly over 60 yr were recruited from a community elderly center. Elderly were classified into young old (60-74 yr) and old (75-84 yr). Metabolic syndrome was defined by third report of the national cholesterol education program (NCEP) expert panel on Adult Treatment Panel III (ATP III). Abdominal obesity was determined by Korean society for the study of Obesity criteria. The nutritional status was measured by mini nutritional assessment (MNA). Results: The prevalence of the metabolic syndrome was significantly higher in the old than young old elderly (p<0.05, respectively). Abdominal obesity and hypertension were the most common risk factors. The related factors to metabolic syndrome were high Body mass Index (BMI) and currently not participating in exercise. Abdominal obesity, low HDL cholesterol and hypertension were associated with specific nutrient intakes. Conclusion: A strategy to decrease the metabolic syndrome in the elderly is urgently needed particularly so for the old elderly. A nutritional and exercise program for young old elders may be helpful reducing the prevalence of metabolic syndrome in later stage.

• 한국동물위생학회지
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• 제14권2호
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• pp.148-153
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• 1991

To investigate epidemological sitution of bovine viral diarrhea infection, serological survey in cattle being raised in Young Dong province were conducted. Bovine sera collected ramdomly from August 1990 to December 1990 were tested for bovine viral diarrhea virus serum neutralizing antibody titers. The results were as follows 1. BVDV SN antibody levels were considerably varies and positive rate was 58(108 heads out of 186) 2. BVDV SN antibodies to breeds of cattle was various and positive rates showed that diary cattle, beef, native cattle(Korean) were 67.52%, 59.38%, 27.00％ respectively followed in that order. 3. In the regional prevalence of BVD SN antibodies in cattle, Alpine(92％) was the highest, Young Dong south(59%) middle(44%), and North 30% followed in that order 4. In the age relatated prevalence of BVD SN antibodies, the younger than 6 month old group was the highest 65.7%, and older than 25 month old group was also at 62.2％. Then, 7 to 12 moth old group and 13 to 24 month old group showed to 58.5%, 52.1％ respectively. 5. The geometric mean titer (log2) of 108 cattle serum samples showing positive BVD SN antibodies was 4.3. 6. In the geometric mean titer(log2) according to age, younger than 6 month old group (5.2) was the highest, then 7 to 12 month old group 2.8(SD=1.94 standard deviation) was lowliest.

• 한국식품저장유통학회:학술대회논문집
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• 한국식품저장유통학회 2003년도 춘계총회 및 제22차 학술발표회
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• pp.97.2-98
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• 2003

The main objective of this study was to investigate the patterns of glucosinolates (3-butenyl isothiocyanate, total glucosinolates) in different parts of young seedling and seeds on Korean Chinese cabbages 55 days and Winter pride cultivars. For determination of glucosinolates, two cultivars of Chinese cabbages seeds and different parts of 1-day-old, 3-day-old, 5-day-old, and 7-day-old seedlings were used for analytical sample preparation provided with an anion exchanges column, and measured by GC and UV-Visible Spectrophotometer. 3-Butenyl ITC concentration was the highest in the cotyledon and the hypocotyl parts of 55 days cultivar seedling. In the cotyledon part of Winter pride cultivar seedling, 3-butenyl ITC amount was increase to 3-day-old seedling and then reduced. The cotyledon of 55 days cultivar contained the highest concentration of total glucosinolates while those were increased in the hypocotyl and decreased by degrees in the root. Total glucosinolates amounts were increased to 5-day-old seedling and then decreased in the cotyledon and the hypocotyl parts of seedling on Winter pride cultivar. There was no significant difference in the root part. In the seeds, both of 3-butenyl ITC and total glucosinolates, 55 days cultivar concentration was higher than Winter pride cultivar. The study has shown the variability in 3-butenyl ITC and total glucosinolates concentrations among cultivars, growth stages, and parts.

• 한국융합학회논문지
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• 제9권12호
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• pp.313-319
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• 2018

본 연구의 목적은 우리나라 만 65세 이상 노인의 연령별 신체활동 및 식생활과 정신건강의 관련정도와 영향요인을 파악하여 노인의 정신건강에 긍정적으로 대처할 수 있는 요인을 확인하고, 노인건강프로그램 개발의 기초자료로 활용하기 위함이다. 본 연구는 2015년도 국민건강영양조사결과를 기초자료로 한 이차자료 분석연구이며, 우리나라 만 65세 이상의 노인 1,484명을 대상으로 하였다. 자료분석은 IBM 23 ver. SPSS를 이용하였다. 본 연구 결과 전기노인은 정신건강변수의 세부항목 중에서 우울감과 스트레스 인지가 높았으며. 후기노인은 자살생각이 높았다. 식생활형편은 전기노인보다 후기노인에서 '음식섭취 부족' 이 높았다. 회귀분석 결과 노인의 식생활 형편, 중강도 신체활동이 노인의 정신건강과 관련성이 있는 것으로 보고되었다. 연구결과를 토대로 세분화된 연령대에 적합한 차별화된 간호중재 프로그램개발이 필요하다.

• 한국응용과학기술학회지
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• 제36권1호
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• pp.59-72
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• 2019

본 논문은 전후기 여성 독거노인의 건강관련 삶의 질 영향 요인을 알아보고자 하는 서술적 조사 연구로 2017년 <여성 독거노인의 통증, 영양위험, 외로움, 지각된 건강상태가 건강관련 삶의 질에 미치는 영향>인 일차연구 자료와 추가 수집한 자료 총 85부를 이용한 이차분석 연구이다. SPSS/WIN 18.0 program을 이용하여 분석한 결과, 전기 여성 독거노인의 건강관련 삶의 질 영향 요인은 통증, 규칙적인 운동, 사회적지지 순으로 설명력 70.6%이며 후기 여성 독거노인의 건강관련 삶의 질 영향 요인은 규칙적인 운동, 일상생활수행능력, 통증 순으로 건강관련 삶의 질에 영향을 주는 것으로 설명력은 69.7%로 나타났다. 따라서 통증 감소를 위한 방안과 사회적지지 체계의 강화, 생활체육 활성화 및 그에 따른 일상생활 수행 유지를 위한 노력 등의 모색을 통해 건강관련 삶의 질을 향상 시킬 필요가 있다.

• 한국콘텐츠학회논문지
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• 제22권2호
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• pp.420-430
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• 2022

이 연구는 전기노인(65세~74세)과 후기노인(75세 이상)의 인구사회학적 특성, 건강관련 행태, 질병이환, 의료이용, 건강관련 삶의 질에 대한 포괄적인 평가를 해 보고자 하였다. 평가를 위해 2015년도부터 2019년도까지 5년간의 지역사회건강조사 자료를 활용하였다. 자료는 SAS 9.4 통계프로그램을 이용하여 카이제곱검정, t-test, ANOVA, 다중회귀분석을 실시하였다. 연구 결과 건강관련 삶의 질은 전기노인이 후기노인보다 높게 나타났고 연령, 교육수준, 가구소득, 경제활동 유무, 중등도 신체활동 유무, 스트레스인지 유무, 주관적 건강수준 등 다양한 요인들이 건강관련 삶의 질에 영향을 미치는 것으로 나타났다. 특히 주관적 건강 수준, 주관적 구강건강 수준이 나쁨과 좋음의 차이는 변수들 중 가장 큰 영향을 미쳤다. 세대유형에서 전기노인은 3세대인 경우, 후기노인은 1세대 인 경우 삶의 질이 높게 나타나는 특징의 차이를 보였다. 이러한 여러 영향 요인을 파악하여 삶의 질을 높이는 방법으로 노인을 위한 정책적인 프로그램이 시행된다면 노인의 삶의 질을 높이는 성공적인 노화에 도움이 될 것으로 생각된다.

• 한국주거학회논문집
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• 제28권1호
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• pp.83-93
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• 2017

This research intends to find out the impact of housing wealth of home-owning pre-retirees and older adults consisting of young-old, middle-old and old-old groups on their household consumption. In doing so, this research analyzes 2,350 home-owning households by utilizing the 17th Korean Labour and Income Panel Study (KLIPS). The results show that housing wealth has a statistically significant effect on non-durable consumption of the pre-retirees, and young-old and middle-old groups of older adults, and housing wealth has a much stronger effect on household expenditure than does financial wealth or real estate. It's found that the consumption elasticity is particularly greater for female-headed households living in SMA, residing in apartments, holding a lower debt-to-asset ratio and being a pensioner. The empirical findings imply that the old-old group of older adults is unlikely to actively tap into their housing windfalls since housing asset becomes the last to dispose in the course of an individual's life. As housing wealth effects are especially strong when liquidity constraints faced by older adults are removed, it's of significance to substantially reduce household debt before retirement in order to constantly maintain an adequate level of household consumption or to promptly prepare for future contingencies.

• 천문학회보
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• 제36권1호
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• pp.63.1-63.1
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• 2011

M82 is a famous starburst galaxy which is dominated by young stellar populations and ISM. Some previous studies indicated the existence of intermediate-age and old stellar population in this galaxy, but little is known about them. We present a study of old globular clusters in M82 using the Hubble Space Telescope archive data. From the cluster survey of M82 we found 650 star clusters. We divided them into disk and halo star clusters according to their position. The color-color diagrams show that all 19 halo star clusters are old globular clusters. The disk sample may include both reddened young clusters and geniune old globular clusters. We estimated their ages using spectral energy distribution fit method with six filter data covering from ultraviolet (F330W) to infrared (F160W), and found that 30 of them are older than 3 Gyr. These are considered to be disk globular clusters. Twelve of the halo globular clusters are found to be partially resolved into their member stars. The (B-V) color range of the halo globular clusters is consistent with that of the Milky Way globular clusters, but most of M82 globular clusters are bluer than (B-V)=0.7. The existence of these old globular clusters suggests that the starburst galaxy M82 has an old stellar halo that may be as old as the Milky Way halo.