• Journal of Nutrition and Health
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• v.35 no.7
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• pp.754-762
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• 2002

This study was performed to investigate the effect of sodium intake on blood pressure and blood parameters. 20 young adult women were fed the diets containing 290.5 mEq (high-Na diet) and 51.3 mEq (low-Na diet) Na for 6 days, respectively. BMI, DBP, and MBP were significantly lower in low-Na diet than those in high-Na diet. 20 subjects were divided into 3 groups according to the salt-sensitivity. In salt-sensitive group, decreases in SBP, DBP, and MBP by low-Na diet were shown. And there were not significant difference in blood pressure of salt-resistant group between high- and low-Na diet. In count-reactive group, MBP in low-Na diet was significantly higher than that in high-Na diet. Hemoglobin, creatinine, uric acid, and haptoglobin levels in serum were significantly higher in low-Na diet than those in high-Na diet. Among groups with different salt-sensitivity, increments of haptoglobin by low-Na diet were shown in salt-sensitive and counter-reactive groups. Actually, low sodium diet affects not only the blood pressure, but other biochemical parameters which in turn affect an individual overall health. Also salt-sensitivity should be considered as an important determinant. Therefore, for the patients who need restricted Na diet, it would be suggested that various biochemical changes and individual salt-sensitivity should be carefully considered along with dietary Na manipulation.

• The Journal of Internal Korean Medicine
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• v.38 no.1
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• pp.20-31
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• 2017

Objectives: This study investigated the effect of SM-2015 on blood alcohol clearance and hangover. We undertook this study to test whether SM-2015 is effective in decreasing blood alcohol concentration and preventing the symptoms of alcohol-induced hangover. Methods: Twenty healthy volunteers participated in this randomized crossover study. All participants were classified between an SM-2015 intake group (test group) and a non-intake group (control group). The primary outcome measure was the difference in blood alcohol concentration and hangover severity scores between the test and control groups. The secondary outcome measure was the difference in a liver function test (LFT) between the test and control groups. Results: After alcohol exposure, the sensitivity scores of blood alcohol concentration and hangover symptoms (sleepiness, dizziness, nausea, weakness, stomach pain, diarrhea, and concentration disorder) were significantly decreased in the SM-2015 intake group compared with the non-intake group. There were no differences in the LFT results between the SM-2015 intake group and the non-intake group. Conclusions: SM-2015 is effective in decreasing blood alcohol concentration and preventing the symptoms of alcohol-induced hangover. Larger studies are required to confirm these findings.

• Journal of the Korean Institute of Intelligent Systems
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• v.16 no.4
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• pp.493-498
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• 2006

In this paper, we propose a blood pressure measurement method using ANFIS. Usually, the maximum and minimum blood pressures are calculated by Maximum Amplitude Algorithm(MAA) method. However, the MAA method has some drawbacks to measure exact blood pressure since it uses a fixed ratio to set the measuring points for everyone without considering individual's special conditions. To solve this problem, the pressures measured by the MMA are trained by ANFIS having self-learning ability. From various experiments, we confirm that the proposed method shows better performance than conventional method.

• Korean Journal of Veterinary Research
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• v.39 no.6
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• pp.1066-1072
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• 1999

The present study was carried out to investigate the blood markers of Cheju horses. The red cell types (blood groups) were tested from 73 Cheju native horses and 118 Cheju racehorses by serological procedures with 23 reagents. The blood group phenotypes observed with high frequency were Pb(34.3%), Qc(56.2%), Qb(15.1%) and genotypes Dbcm/dghm(12.3%), Dde/dghm(9.6%), Dad/bcm(6.8%), Dcgm/de(6.8%) in Cheju native horses, while Aa(63.6%), Pa(44.9%), P-(28.8%), Qabc(36.4%), Dbcm/cgm(14.4%), Dbcm/bcm(10.2%), Dbcm/de(7.6%), Dbcm/dghm(5.1%), Dde/dk(5.1%) in Cheju racehorses. Alleles observed with high frequency were Ab(0.128), Ac(0.169), Dad(0.103), Dadn(0.075), Ddghm(0.226), Pb(0.316), Qc(0.494) in Cheju native horses and Aa(0.529), Dbcm(0.306), P-(0.531), Qabc(0.197), Q-(0.504) in Cheju racehorses. No specific variation of blood groups and allele frequencies of C,K,U system were observed in Cheju native horses and Cheju racehorses. The mean heterozygosity in Cheju native horses and Cheju racehorses was observed 0.5344 and 0.5102, respectively.

• Journal of Korean Academy of Fundamentals of Nursing
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• v.12 no.3
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• pp.307-316
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• 2005

Purpose: The purpose of this study was to identify 24 hours blood pressure variations among adults over 40 years of age. Method: The participants(50 adults) were recruited from P hospital and B company. The participants were divided into normotensive and hypertensive tendency groups and then sub-divided into non-dipper, dipper, and extreme dipper. The data were collected from April, 2003 to September, 2004 and analyzed using SPSS for Window program. Results: 1) There were significant differences in cardiovascular risk factor, systolic and diastolic blood pressures, and LDH, diet between the normotensive and hypertensive tendency groups. 2) Dippers in both groups showed a marked decrease in blood pressure during the night, but non-dippers in both groups didn't show a marked nocturnal decrease in blood pressure. 3) There were significant differences in heart rate, WHR, BMI, LDH, triglyceride, glucose, affective-oriented coping strategies between dippers and non-dippers. 4) There were significant differences in heart rate, WHR, BMI, LDH, triglyceride, affective-oriented coping strategies between dipper and non-dipper within hypertensive tendency group. Conclusion: Further studies are needed to provide effective intervention in hypertension when applying 24 hour blood pressure monitoring.

• Physical Therapy Korea
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• v.1 no.1
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• pp.75-82
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• 1994

The purpose of this study is to determine cardiovascular reponses to concentric, eccentric and isometric exercise applied to the knee extensor muscle group. Exercise types studied were concentric, eccentric and isometric. The subjects were sixty healthy male volunteers who had no hypertension or cardiac disease. Heart rate, systolic and diastolic blood pressure were recorded prior to starting exercise. The subjects also performed 10RM on right lower extremity. A N-K table was used for three exercises to right knee extensors. Each exercise was selected randomly and applied to each subject 10 times in a 10 second. After each exercise, heart rate, systolic and diastolic blood pressure were recorded immediately. Findings were as follows concectric contractions had a greater effect on the increase of systolic blood pressure and heart rate than eccentric or isometric contractions. Diastolic blood pressure is influenced only by isometric contractions. Eccentric contractions have less effect on the increase of systolic blood pressure and heart rate than concentric or isometric contractions. We hope that the results of this experiment can be adapted to exercise programs for patients with cardiac disease.

• Journal of the Korean Society of Food Science and Nutrition
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• v.24 no.4
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• pp.493-501
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• 1995

To investigate an effect of dietary sodium and potassium on blood pressure, 418 adolescents living in Kangwha area were studied. Two measurements were taken on each blood pressure(diastolic, systolic) and the average of the two readings was used in the analysis. Sodium and potassium intake were estimated by the determination of those electrolytes in 24hr urine. Not only dietary factors but also physical growth factors such as weight, height, arm-circumference and skinfold-thickness were induced in the stepwise multiple regression analysis to indentify the relative importance between the factors. The variation of blood pressure both in systolic and diastolic in both sexes was inconsistent with the levels of sodium and potassium intake. The results of multiple regression analysis showed that the physical growth were more influential than nutrient factor. It suggested that hypertension risk factors observed form the adults, may not be identical with that of the growing aged population. After control of the physical growth, there was no significant variation observed by the level of sodium and potassium intake on blood pressure. In summary, the results indicate that growth has been more influential than dietary factor on blood pressure for growing aged population.

• Korean Journal of Community Nutrition
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• v.11 no.6
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• pp.707-713
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• 2006

The purpose of this study was to test whether moderate alcohol consumption has any positive effect on lowering blood pressure among Koreans. Study subjects were Korean adults 20 years or older (n=5,234) who participated in the 2001 Korean National Health and Nutrition Examination Survey (KNHANES). Analysis of variance and analysis of covariance were used to construct univariate and multivariate models relating alcohol consumption to blood pressure for the analysis. After adjustment for possible covariates, drinkers (regardless of drinking level) had significantly higher systolic and diastolic blood pressure, compared with never-drinker for male subjects. Diastolic and systolic blood pressures were also significantly elevated with the drinking frequency and amount of alcohol intake among male subjects. For the female subjects, only diastolic blood pressure was significantly associated with the alcohol consumption at multivariate model. however, low level alcohol consumption did not show any sign of lowing effects on blood pressure. The result implies that moderate alcohol consumption did not have any positive effect on lowering blood pressure among Koreans for either sex.

• Molecular & Cellular Toxicology
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• v.4 no.1
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• pp.61-65
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• 2008

Although dietary intake of pregnant is supposed to have beneficial effects on development of infants, it may be harmful for fetal growth and development since specific food is a common source of toxicants including heavy metal. The purpose of this study was to investigate the association of maternal food intake and mid-pregnancy and their newborns blood lead levels. Pregnant women of 18-20 weeks of gestation were recruited from prenatal clinic in Seoul, Cheonan and Ulsan. In 422 pregnant women, dietary intake during pregnancy was assessed by a 24-hour recall method. Blood sample from pregnant (18-20 wks) and their cord blood at delivery were collected. Blood leas levels were analyzed by atomic-absorption spectrometry methods. Pregnant blood lead levels whose meat and meat products intake were in the highest quartile was significantly higher compared to the lowest quartile. Maternal meat and meat products intake was positively correlated maternal blood lead level (r=0.120, P=0.014). After adjusting for age, maternal blood lead level was positively correlated with their newborn blood lead level (r=0.303, P=0.030). As maternal food intake effects on blood lead levels of pregnant, careful regulation of food intake during pregnancy is perceives to be important in order to bring about desirable pregnancy outcomes.

• Journal of Environmental Science International
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• v.22 no.1
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• pp.59-72
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• 2013

The purpose of this study is to assess the effects of heavy metal concentrations in the blood and urine of the general population. This research had been conducted from April to December 2008, studying 545 residents of Daejeon and Chungcheong Province. Through the concentrations of heavy metals(Pb, Cd, Hg, As, Mn) in the biota samples and questionnaires, the residents heavy metal exposure level and the influential factors according to personal characteristics or lifestyle were evaluated. As to the heavy metal concentration in the blood and urine of the comparing region, were As and Mn statistically significant(p<0.01, p<0.05). Blood lead and urinary mercury concentrations were higher in males than females. The heavy metal concentration for each age group increased blood mercury. The concentration of all heavy metals were higher in the drinkers than in the non-drinkers. Blood lead and mercury concentrations were higher in the smokers than in the non-smokers, but the urinary cadmium, arsenic and blood manganese was higher in the non-smokers than in the smokers. As to the blood lead and urinary cadmium concentration according to the food preference fish showed high concentration. To clarify the factors affecting the heavy metal concentration in biota among subjects multiple regression analysis was conducted. As a results, it turned out that as to lead content in blood, sex, age and smoking have influence on the subjects with explanatory adequacy of 14.0 %. These results demonstrated that the factors affected the concentrations of heavy metals in blood and urine. The results of this study could be used as the foundational data for setting the health risk assessment.