Molecular & Cellular Toxicology

The Korean Society of Toxicogenomics and Toxicoproteomics (대한독성유전 단백체학회)
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The Association of Maternal Food Intake and Blood Lead Levels in Pregnant and Their Newborns

  • Lee, Ah-Young (Department of Nutritional Sciences, Ewha Womans University) ;
  • Kim, Hye-Sook (Department of Nutritional Sciences, Ewha Womans University) ;
  • Kim, Ki-Nam (Department of Nutritional Sciences, Ewha Womans University) ;
  • Ha, Eun-Hee (Department of preventive Medicine, College of Medicine, Ewha Womans University) ;
  • Park, Hye-Sook (Department of preventive Medicine, College of Medicine, Ewha Womans University) ;
  • Ha, Mi-Na (Department of preventive Medicine, Dankook University College of Medicine) ;
  • Kim, Yang-Ho (Department of Occupational and Environment Medicine, Ulsan University Hospital, University of Ulsan College of Medicine) ;
  • Hong, Yun-Chul (Department of Preventive Medicine, Seoul National University College of Medicine) ;
  • Chang, Nam-Soo (Department of Nutritional Sciences, Ewha Womans University)
  • Published : 2008.03.31
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Abstract

Although dietary intake of pregnant is supposed to have beneficial effects on development of infants, it may be harmful for fetal growth and development since specific food is a common source of toxicants including heavy metal. The purpose of this study was to investigate the association of maternal food intake and mid-pregnancy and their newborns blood lead levels. Pregnant women of 18-20 weeks of gestation were recruited from prenatal clinic in Seoul, Cheonan and Ulsan. In 422 pregnant women, dietary intake during pregnancy was assessed by a 24-hour recall method. Blood sample from pregnant (18-20 wks) and their cord blood at delivery were collected. Blood leas levels were analyzed by atomic-absorption spectrometry methods. Pregnant blood lead levels whose meat and meat products intake were in the highest quartile was significantly higher compared to the lowest quartile. Maternal meat and meat products intake was positively correlated maternal blood lead level (r=0.120, P=0.014). After adjusting for age, maternal blood lead level was positively correlated with their newborn blood lead level (r=0.303, P=0.030). As maternal food intake effects on blood lead levels of pregnant, careful regulation of food intake during pregnancy is perceives to be important in order to bring about desirable pregnancy outcomes.

Keywords

References

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