• 대한의용생체공학회:의공학회지
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• 제31권3호
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• pp.187-193
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• 2010

In this study we have designed and fabricated an inexpensive micro electronic system that we call Alvitek. It can indirectly but accurately predict and display the partial pressures of alveolar oxygen and carbon dioxide for the patients in the ICU of a hospital. Alvitek consists of both hardware part and software part. Performance of the system is tested by animal experiment with pigs for various $F_{t}e_{2}$ and RR(Respiratory Rate) values under the mechanical ventilation. The predicted alveolar gas partial pressures are cprpared with the approximate alveolar oxygen partial pressures easily calculated by the physician’s bedside formula. As a result, we have concluded that the relative error of A-$aDe_2$ calculated by the bedside formula grows seriously for lower $F_{t}e_{2}$ values. The present prediction method of Alvitek is henceforth believed very meaningful to the physicians. The system hardware and software are described in the text.

• 한국임상수의학회지
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• 제23권4권
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• pp.458-460
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• 2006

체중 3.8 kg의 2년령 암컷인 잡종견이 10일전부터의 구토 및 식욕저하를 주증상으로 내원하였다. 이 개는 2개월 전에 자동차 사고에 의한 골반골절로 진단되었으나, 골절은 정복되지 아니 하였다. 2개월 후에 간헐성의 구토 및 식욕부진으로 고통을 받았다 Barium조영 방사선 검사에서, 장폐색으로 진단되었다. 외과수술을 통하여 골절 부위에서 장의 교액 및 유착에 의한 폐색이 확인되었다. 수술후 18개월이 경과된 시점에서 확인한 결과, 전신적인 신체상태가 양호하였다.

• 한국동물위생학회지
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• 제40권1호
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• pp.53-59
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• 2017

Foot and mouth disease (FMD) is highly infectious disease of cloven-hoofed animals, particularly problematic in cattle, sheep, pigs and goats for economic reasons. Last FMD outbreak in February, 2017 caused tremendous social and economical impacts. The Korean FMD policy aims to vaccinate intact animals and euthanize and bury infected animals to prevent the disease spread. However, there was a problem that the buried livestock did not decompose after several years. Therefore, the study was purposed to investigate the effect of Corynebacterium glutamicum and Bacillus licheniformis on the degradation of buried cow carcasses and on the soil condition; such as temperature, decomposition course of carcasses, composition of amino acids in the soil around carcasses, and plant root elongation to measure soil conditions. As a result, the composition of amino acids in the soil treated with C. glutamicum and B. licheniformis was generally higher than those in the untreated soil. Plant roots in soil treated with C. glutamicum and B. licheniformis grew longer than in non-treated soil. The results suggested that the toxic effect on a grave land buried with FMD infected livestock is reduced when treated with C. glutamicum and B. licheniformis in regard of odor reduction, promoted decaying process, and soil fertilization.

• 한국의사학회지
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• 제33권1호
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• pp.43-57
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• 2020

Essence of the Hwangchil tree (黃漆樹 Dendropanax morbiferus H.Lév.) has been used for various purposes, like waxing emperor's armors, covering an astrology board, or, during the Silla Dynasty, burying it to block something bad in the soil symbolically. Essence of the Hwangchil tree was known to have remarkable preservation effects such as waterproofing, damp-proofing, rust-proofing, and moth-proofing as well as not being easily peeled off from even soft surfaces like paper. There is a record in Prescriptions for Epidemic diseases of Cows, Horses, Sheep, and Pigs (牛馬羊猪染疫病治療方), published in 1541, of Hwangchil that is local to Jeju Island being used instead of benzoin (安息香), of burning Hwangchil, and of making cows inhale its smoke to prevent plague among them. Along the same lines, there are records in the Local Chronicle of Tamra (耽羅志) and the Book of Earth Geography (輿地圖書) that identify Hwangchil with benzoin. In Seonghosaseol (星湖僿說), a book written by Lee Yik in around 1760, it is acknowledged that Hwangchil could be medicinal herb. In 2000, Ahn Duk-Kyun registered the roots and branches of Hwangchil tree as 'Boncho' (本草 herbal medicine) in the Pictorial Book of Korean Medicinals (韓國本草圖鑑) and presented the method of taking it for medical purpose. Researchers have suggested that Hwangchil essence as well as diverse parts of the plant such as its roots, branches, leaves, flowers, fruits, and gum have various meaningful medicinal properties. Regarding the history and recent researches of using Hwangchil tree, it has various medicinal probabilities such as, 'dispersing miasma' (辟邪), 'opening holes' (開竅), 'waking the heart' (醒心), 'smoothing spirits' (安神), 'piercing the block' (疎泄), 'removing the old and welcoming the new' (去故生新). This paper contributes ideas about how to expand the uses of Hwangchil Tree.

• 한국인터넷방송통신학회논문지
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• 제15권2호
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• pp.203-211
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• 2015

신약개발이나 동물연구 등에서 연구대상 동물이 케이지(cage) 안에서 자유롭게 움직이고 있는 상태에서 무선으로 다량의 데이터를 수집하는 장치는 실험동물 신체 내부에 배터리로 구동되는 소형발신기를 내장시켜 혈압, 온도, 심박수, Electrocardiogram(ECG), Electroencephalography(EEG) 등의 정보를 근접통신을 통해 근처의 수신기로 전달하게 된다. 이러한 장비는 한정된 내부의 배터리를 이용하기 때문에 측정시간의 한계가 있으며, 이러한 문제를 해결하기 위해서 전자기유도방식의 단점인 발신부와 수신부사이의 거리가 멀어질 때 발생하는 효율저하문제를 극복하기 위하여 다중코일 구조를 이용한 무선전력전송 구동 드라이버를 제안하였으며, 다중코일 중 수신부가 놓인 코일을 선택하기 위한 수신부 감지 장치도 제시되었다. 또한 실험을 통하여 제안된 구동드라이버 및 수신부 감지 회로의 구동 조건 선정 과정을 제시하였다.

• Reproductive and Developmental Biology
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• 제41권1호
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• pp.17-23
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• 2017

The oocyte undergoes various events during in vitro maturation (IVM) and subsequence development. One of the events is production of reactive oxygen species (ROS) that is a normal process of cell metabolism. But imbalances between ROS production and antioxidant systems induce oxidative stress that negatively affect to mammalian reproductive process. In vitro environments, in vitro matured oocytes have many problems, such as excessive production of ROS and imperfect cytoplasmic maturation. Therefore, in vitro matured oocytes still have lower maturation rates and developmental competence than in vivo matured oocytes. In order to improve the IVM and in vitro culture (IVC) system, antioxidants, vitamins were added to the IVM, IVC medium. Antioxidant supplementation was effective in controlling the production of ROS and it continues to be explored as a potential strategy to overcome mammalian reproductive disorders. Based on these studies, we expect that the use of antioxidants in porcine oocytes could improved maturation and development rates.

• 분석과학
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• 제30권6호
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• pp.338-347
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• 2017

본 연구의 목적은 돼지와 소를 대상으로 우리나라 대표 토양인 사양질, 식양질, 사질의 토양에 따른 실험실 규모 가축 매몰지를 설치하여 3년동안 분해특성을 살펴보는 것이다. 그 결과 가축 매몰지역 환경조사지침에 따른 가축 매몰지 발굴금지기간인 3년을 기준으로 대부분 분해되는 것을 확인하였으며, 사체분해를 위해 중요인자로 온도, 수분, pH, 토성, 영양소, 매몰지 깊이 등 다양한 외부환경 요인이 적절히 유지되어야 할것으로 판단되었다. 또한 소의 경우가 돼지보다 빠르게 분해되었는데, 토양에 따른 분해속도를 확인한 결과 사질 > 식양질 > 사양질 순으로 분해가 이루어지는 것으로 판단되었다.

• 환경영향평가
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• 제21권4호
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• pp.543-552
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• 2012

Namgang mid-watershed is located in downstream of Nakdong river basin. There are many pollution sources arround this area and it's control is important to manage a water quality of Nakdong river. A target year of Namgang mid-watershed water environment management plan is 2013. To predict a water quality at downstream of Namgang, we have investigated and forecasted the pollutant source and it's loading. There are some plan to construction the sewage treatment plants to improve the water quality of Nam river. Those are considered on predicting water quality. As results, it is shown that the population is 343,326 and sewerage supply rate is 79.2% and the livestock is 1,662,000 in Namgang mid-watershed. It is estimated that the population is 333,980, the sewerage supply rate is 86.9% in 2013. The milk cow and cattle were estimated upward and the pigs were downward by 2013. The generated loading of BOD and TP is 75,957 kg/day and 4,311 kg/day, discharged loading is 18,481 kg/day and 988 kg/day respectively in 2006. It were predicted upward the discharged loading of BOD and TP by 4.08% and 6.3% respectively. The results of water quality prediction of Namgang4 site were 2.5 mg/L of BOD and 0.120 mg/L of TP in 2013. It is over the target water quality at that site in 2015 about 25.0% and 9.1% respectively. Consequently, there need another counterplan to reduce the pollutants in that mid-watershed.

• 한국동물위생학회지
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• 제29권1호
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• pp.19-26
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• 2006

Bee venom is synthesized in the venom gland's of worker and queen bees and stored in their venom sacs. Bee venom is a rich source of enzymes, peptides and biogenic amines. there are at least 18 active components in the venom which have some pharmaceutical properties. This study was performed to evaluate minimum inhibitory concentration(MIC) of bee venom against bacteria isolated from pjgs and chickens with disease. In case of reference strains, the MIC $({\mu}g/m{\ell})$ of Staphylococcus aureus ATCC 6538, Streptococcus mutans ATCC 25175, and Salmonella typhimurium ATCC 6538 were 64, 64 and 32, respectively. In case of bacteria isolated from pig and chicken, the MIC of Staphylococcus aureus, Staphylococcus hyicus and Staphylococcus chromogenes were 8, 128 and 128, and that of 11 strains of Escherichia coli were 8 to >512 and that of 8 strains of Salmonella sup were >512. Antibacterial resistance test of 22 strains isolated from pig and chicken and 3 reference strains were performed by agar gel diffusion method, using 17 antibacterial drugs including penicillin, cefazolin, tetracycline and quinolone group. The multiple drug resistant patterns were found in most strains isolated from pig and chicken.

• 대한수의학회지
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• 제44권2호
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• pp.259-268
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• 2004

Porcine circovirus type 2 (PCV-2) has been associated with various disease in pigs worldwide including postweaning multisystemic wasting syndrome (PMWS) and porcine dermatitis and nephropathy syndrome (PDNS). In this study, monoclonal antibodies (MAbs) against PCV were produced, characterized and applications of MAbs as diagnostic reagents were described. Spleen or lymph node cells from BALB/c mouse immunized respectively with PCV-1, PCV-2 or expressed PCV-2/ORF2 proteins in baculovirus were fused with SP2/0 myeloma cells using polyethylene glycol (PEG) and hybridoma cells producing PCV-1 or PCV-2-specific antibody were screened by an indirect immunofluorescence (IIF) test. A total of fifteen MAbs were produced against PCV. Six MAbs were PCV-1-specific and nine were PCV-2-specific. All PCV-1-specific MAbs reacted with only PCV-1 and all PCV-2-specific MAbs were reactive with only PCV-2 by IIF test. None of the MAbs was reactive with porcine reproductive and respiratory syndrome virus (PRRSV), porcine parvovirus (PPV), porcine rotavirus (PRV), and transmissible gastroenteritis virus (TGEV). Some PCV-2-specific MAbs recognized the PCV-2 infected porcine tissues by IIF or immunohistochemistry (IHC) assay. From this experiment, it was confirmed that MAbs produced in this study were PCV-specific and could be used as reliable diagnostic reagents for PCV-1/PCV-2 detection and differentiation.