• Proceedings of the Korean Society of Crop Science Conference
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• 2019.09a
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• pp.209-209
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• 2019

• Natural Product Sciences
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• v.26 no.4
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• pp.289-294
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• 2020

Eclipta prostrata is an annual herb, belonging to Asteraceae family, and has been traditionally used to improve immunity and treat hepatitis and bacterial disease in Korea. In this study, a new coumestan glucoside (1) along with ten known compounds (2 - 11) was isolated from E. prostrata. The chemical structures of isolates were elucidated to be wedelolactone-9-O-β-D-glucopyranoside (1), wedelolactone (2), demethylwedelolactone (3), apigenin (4), apigenin-7-sulfate (5), luteolin (6), luteolin-7-sulfate (7), luteolin-7-O-β-D-glucopyranoside (8), pratensein-7-O-β-D-glucopyranoside (9), 3,4-di-O-caffeoylquinic acid (10) and 3,5-di-O-caffeoylquinic acid (11) based on the spectroscopic evidence.

• Proceedings of the PSK Conference
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• 2003.10b
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• pp.169.2-170
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• 2003

Erythropietin (EPO), a hematopoietic factor is also required for normal brain development, and its receptor is localized in brain. Therefore, it is possible that EPO could act as a neurotropic factor inducing differentiation of neurons. The present study, we therefore investigated whether EPO can increase differentiation of undifferentiated cortical neuron isolated from postneonatal (Day 1) rat brains and PC12 cell, undifferentiated dopaminagic cell line. EPO dose (1-100 U/ml) dependently increased cell differentiation and expression of differentiation marker gene (neurofilament and tyrosine hydroxylase) in both cells. (omitted)

• Natural Product Sciences
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• v.27 no.4
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• pp.240-244
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• 2021

Aegle marmelos (Rutaceae) is a deciduous shrub or tree and typically known as bael throughout Southeast Asia and has been used as a medicinal plant and a food ingredient. In this study eight compounds were determined to be O-(3,3-dimethylallyl) halfordinol (1), (R)-aegeline (2), (R)-marmeline (3), imperatorin (4), xanthotoxol (5), valencic acid (6), vanillic acid (7) and rutin (8). The chemical structures of the isolates were elucidated through spectroscopic evidence including 1D, 2D NMR, ESI-Q-TOF-MS and optical rotation.

• International conference on construction engineering and project management
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• 2005.10a
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• pp.1100-1105
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• 2005

To compete with large construction companies whose dominance in market share is deepening recently, the needs for improving field production system of mid-size construction companies have increased rapidly. The development of an adequate model that focuses on the organizational size and work process of the mid-size construction companies are needed to increase productivity through the informatization in the construction industry[0]. The authors of this study used case studies on the problems of the mid-size construction companies in procuring work and presented a method to solve such problems so that the managers in head office of those mid-size construction companies can effecitively deal with multiple sites[0].

• Proceedings of the Korea Information Processing Society Conference
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• 2020.11a
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• pp.189-192
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• 2020

가상현실 기술과 IoT 센서와 연결하여 스마트 항만 원격조정하는 프로그램을 설계하였다. 스마트 항만은 항만 자동화 추세에 맞춰진 현대의 항만 시스템이며 그에 따른 기술력 확보가 국가의 경쟁력을 높이는 핵심이 된다. 아두이노로 하드웨어를, 유니티로 소프트웨어 부분을 설계하여 진행했다.

• Proceedings of the Korean Society of Broadcast Engineers Conference
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• 2020.11a
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• pp.347-350
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• 2020

본 논문에서는 영상 변환 기술인 이산웨이블릿변환(Discrete Wavelet Transform, DWT)를 딥러닝 기반의 네트워크로 구현한다. 딥러닝 기술 중에도 CNN 기반으로 네트워크를 설계하였으며, 본 DWT 네트워크는 해상도에 의존적이지 않은 계층들로만 구성된다. 데이터세트를 구성할 때 파이썬의 라이브러리를 사용하여 레이블 데이터세트를 구성한다. 128×128크기의 gray-scale 영상을 입력으로 사용하고 이에 대응하는 레이블 데이터세트를 구성하여 1-level DWT를 수행하는 네트워크의 학습을 진행한다. 역방향 변환도 네트워크 설계 후 데이터세트를 구성하여 학습을 진행한다. 학습이 완료된 1-level DWT 네트워크를 반복적으로 사용하여 Multi-level DWT 네트워크를 구성한다. 또한 양자화에 의한 간단한 영상압축 실험을 진행하여 DWT 네트워크의 성능과 압축 등의 응용분야에 활용할 수 있음을 보인다. 설계한 DWT 네트워크의 1-level 순방향 변환 성능은 42.18dB의 PSNR을 보였고, 1-level 역방향 변환 성능은 50.13dB의 PSNR을 보였다.

• Proceedings of the Korea Information Processing Society Conference
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• 2023.11a
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• pp.1254-1256
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• 2023

반도체 공정은 주로 진공 중에서 이루어 지며 진공을 잘 유지하는 것이 매우 중요하고 여러 가지 종류의 펌프가 사용이 된다. 저진공펌프로 많이 사용되는 로타리 펌프에 대해서 진동 및 온도센서를 부착하고 펌프의 상태에 따른 진동의 변화 및 온도의 변화를 연구 하고 펌프의 예지 보전에 활용할 수 있도록 하였다.

• International Journal of Stem Cells
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• v.17 no.2
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• pp.130-140
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• 2024

Cardiac organoids have emerged as invaluable tools for assessing the impact of diverse substances on heart function. This report introduces guidelines for general requirements for manufacturing cardiac organoids and conducting cardiac organoid-based assays, encompassing protocols, analytical methodologies, and ethical considerations. In the quest to employ recently developed three-dimensional cardiac organoid models as substitutes for animal testing, it becomes imperative to establish robust criteria for evaluating organoid quality and conducting toxicity assessments. This guideline addresses this need, catering to regulatory requirements, and describes common standards for organoid quality and toxicity assessment methodologies, commensurate with current technological capabilities. While acknowledging the dynamic nature of technological progress and the potential for future comparative studies, this guideline serves as a foundational framework. It offers a comprehensive approach to standardized cardiac organoid testing, ensuring scientific rigor, reproducibility, and ethical integrity in investigations of cardiotoxicity, particularly through the utilization of human pluripotent stem cell-derived cardiac organoids.

• Archives of Plastic Surgery
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• v.45 no.1
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• pp.14-22
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• 2018

Background Liposuction has become one of the most frequently performed procedures in the field of aesthetic surgery. Fat embolism syndrome after liposuction can easily be overlooked or underestimated; however, occasionally, fulminating fat embolism syndrome can develop and lead to a critical situation within 2-3 days after lipoplasty. Changes over time in the amount of circulating fat particles and the histology of major organs have not yet been studied. Methods This study was conducted using 18 male Sprague-Dawley rats aged 12 weeks and weighing 500-628 g (average, 562 g). Fifteen rats were used as the experimental group and 3 as the control group. Under general anesthesia, tumescent-technique liposuction was performed at the lateral flank areas and abdomen for 1 hour. Blood, lung, and brain tissue specimens were obtained at 1 hour, 1 day, and 2 days after the liposuction procedure. Results The average number of fat particles in the blood samples was 25,960/dL at 1 hour, 111,100/dL at 24 hours, and 21,780/dL at 48 hours. The differences between study groups were statistically significant. Both intravascular and extravascular fat particles with inflammation were seen in all 15 rats, as were inflammatory cell infiltration, hemorrhage, and consolidation with shrinkage of the lung alveoli. Conclusions These results imply that there is a strong possibility of fat embolism syndrome after liposuction in real clinical practice, and the first 24-48 hours after the operation were found to be the most important period for preventing pulmonary embolism and progression to fulminating fat embolism syndrome.