• 한국컴퓨터정보학회논문지
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• 제20권2호
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• pp.79-88
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• 2015

본 논문에서는 차세대 항공 관제시스템의 핵심이라고 할 수 있는 ADS-B 지상 감시장비를 소개하고, ADS-B 1090ES 지상국 수신기를 연구하였다. 국제 표준 문서와 기존 제품의 성능을 분석하여 성능과 신뢰성이 보장되는 최적의 규격을 결정하였다. 초단인 RF단은 저전력, 저잡음, 고이득 특성에 적합한 바이어스 회로를 구성하여 설계하였으며, 신호처리부는 수신 악조건 하에서도 최적의 신호처리(복호)가 가능하도록 구성하였다. 또한 최종단이라고 할 수 있는 MCU부는 외부와의 고속 통신을 고려하여 최신의 CPU를 채택하여 구성했으며, 원격제어 통신은 SNMP를 채택하였다. 개발된 수신기는 국내외 기술 기준을 모두 만족하며, 외산 제품보다 성능 면에서 비교 우위에 있는 것으로 판단된다.

• 한국자원식물학회지
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• 제18권1호
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• pp.57-63
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• 2005

인삼 callus의 기내배양에 의해서 항암물질을 대량생산하기 위한 연구의 일환으로 인삼 callus의 polyacetylene생산에 미치는 전구물질 및 elicitor의 효과를 조사하였다. 5mg/l의 L-phenylalanine첨가배지에서 인삼 callus의 생장과 polyacethylene합성이 가장 양호하였으며 panaxynol뿐만 아니라 panaxydol도 형성되었다. 반면에 $\alpha-methyl-D.L.methionine$과 D.L.-norleucine 첨가구에서는 polyacetylene이 전혀 생성되지 않았다. Elicitor로 사용되는 nigeran은 농도가 높아질수록 인삼 callus의 생장을 억제시키지만 polyacetylene생성에는 전혀 영향을 미치지 못했다. 그러나 chitosan은 0.5mg/l의 농도에서 는 인삼 callus의 생장과 polyacetylene의 생성에 영향을 주지 못하였으나, 1mg/l 이상 처리구에서는 panaxynol은 검출되지 않았지만 panaxydol은 검출되었다.

• 한국수자원학회:학술대회논문집
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• 한국수자원학회 2012년도 학술발표회
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• pp.248-248
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• 2012

산사태나 토석류와 같은 산지재해가 빈발하고 인명과 재산의 피해가 증가함에 따라 적절한 대책이 시급하게 요구되고 있다. 이런 대책 중에서 신뢰도 높은 산지재해 예, 경보시스템을 구축하는 것은 매우 중요하다. 산림청에서는 산사태 예, 경보 발령을 위한 기준을 마련하고 있으나, 좀더 신뢰도 높은 기준을 필요로 한다고 생각된다. 본 연구에서는 강우분석을 통해서 우리나라의 자연사면에서 토석류, 산사태를 일으키는 강우의 특성을 파악하고, 나아가 산지토사재해 예, 경보시스템에 적절하게 활용될 수 있는 기준을 마련하고자 하였다. 이를 위해서 회귀분석, 판별분석을 적용하여 평가하였고, 보다 개선된 기준으로서 토양우량지수를 제시하였다. 토양우량지수는 강우에 의해 지반이 어느 정도 포화되어 있는가를 계산하여, 토사재해발생의 위험성을 나타낸 것이다. 본 연구에서는 2001년에서 2009년 사이에 충북 제천시 일대의 강우자료를 조사하여 탱크모델에 적용하여 각 탱크에서의 저류량을 계산하여 토양우량지수를 결정하였다. 세 개의 탱크 중에서 두 번째 탱크에서의 저류량 (S2)과 전체 탱크에서의 저류량 (TS)을 이용하여 상위에 랭크된 이력순위를 분석한 결과, S2에서는 산사태가 발생한 2009년 이력이 3번째 높은 수준으로 기록되며, 산사태 미발생의 2007년 강우는 5번째로 기록되었다. 그리고 TS의 경우 2009년 강우가 2002년에 이어 3번째 높은 수준으로 기록되었으며, 2007년 강우는 9번째로 기록되었다. 이러한 결과를 볼 때 토양우량지수의 이력순위는 산지토사재해의 발생을 잘 반영하는 것으로 나타났다. 또한 2011년 발생한 우면산 산사태를 대상으로 토양우량지수를 적용하여 예, 경보시스템의 적용가능성을 판단하였다.

• Acute and Critical Care
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• 제33권4호
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• pp.222-229
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• 2018

Background: The diagnosis of pediatric acute respiratory distress syndrome (PARDS) is a pragmatic decision based on the degree of hypoxia at the time of onset. We aimed to determine whether reclassification using oxygenation metrics 24 hours after diagnosis could provide prognostic ability for outcomes in PARDS. Methods: Two hundred and eighty-eight pediatric patients admitted between January 1, 2010 and January 30, 2017, who met the inclusion criteria for PARDS were retrospectively analyzed. Reclassification based on data measured 24 hours after diagnosis was compared with the initial classification, and changes in pressure parameters and oxygenation were investigated for their prognostic value with respect to mortality. Results: PARDS severity varied widely in the first 24 hours; 52.4% of patients showed an improvement, 35.4% showed no change, and 12.2% either showed progression of PARDS or died. Multivariate analysis revealed that mortality risk significantly increased for the severe group, based on classification using metrics collected 24 hours after diagnosis (adjusted odds ratio, 26.84; 95% confidence interval [CI], 3.43 to 209.89; P=0.002). Compared to changes in pressure variables (peak inspiratory pressure and driving pressure), changes in oxygenation (arterial partial pressure of oxygen to fraction of inspired oxygen) over the first 24 hours showed statistically better discriminative power for mortality (area under the receiver operating characteristic curve, 0.701; 95% CI, 0.636 to 0.766; P<0.001). Conclusions: Implementation of reclassification based on oxygenation metrics 24 hours after diagnosis effectively stratified outcomes in PARDS. Progress within the first 24 hours was significantly associated with outcomes in PARDS, and oxygenation response was the most discernable surrogate metric for mortality.

• 한국정보통신학회:학술대회논문집
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• 한국정보통신학회 2014년도 추계학술대회
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• pp.189-192
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• 2014

최근 미국과 유럽 등 항공 선진국들은 효율적인 항공교통관리를 위해 기존 레이더 시스템을 대체할 차세대 항행시스템으로 위성기반항행시스템(CNS/ATM)에 많은 관심을 가지며 지속적으로 연구를 수행하고 있다. 본 논문은 CNS/ATM의 감시 기술 중 하나인 ADS-B 1090ES 시스템의 수신기 복조부 설계 및 구현에 대한 연구를 하였다. 본 연구는 RTCA DO-260B와 EUROCAE ED-129에서 제시된 모든 성능을 만족하며, 수신감도, 다이나믹 레인지 등의 핵심 성능 향상을 위한 최적화된 알고리즘을 제안하고 수신기 복조부의 균일한 성능을 내기위해 신호레벨 튜닝 메커니즘을 구현하여 하드웨어 제작 공정에 따른 균일하지 못한 신호레벨 차이에 대한 수신율 문제를 최소화 하였다. 분석 결과 제안된 알고리즘은 우수한 성능을 나타냈으며, 이와 유사한 변조방법을 사용하는 시스템에 널리 응용이 가능할 것으로 사료된다.

• 대한한의학회지
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• 제44권4호
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• pp.121-135
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• 2023

Objectives: This study aimed to establish and provide reliable information for general public, based on expert consensus, on the risks of misuse of medicinal herbs for food and pure food ingredients for the fetus during pregnancy. Methods: A panelist of seven traditional Korean medicine (TKM) gynecologists responded to a questionnaire summarizing the fetal safety literature for twenty-five medicinal herbs for food and pure food ingredients derived from medicated diet (藥膳, Yaksun) recipes during three online Delphi rounds anonymously. Results: Ginkgonis Semen (Ginkgo nut), Illici Veri Fructus (Star anise), lavender, bitter gourd, and parsley were agreed at the level 1 of "Do not consume". These five ingredients were recognized as having significant risks both in the literature evidence and in expert opinion. Rosemary, Citri Unshius Pericarpium, Discoreae Rhizoma, lemongrass, Schisandrae Fructus, Cassiae Semen, Foeniculi Fructus, Mori Fructus, Cinnamomi Cortex, and Astragali Radix were agreed at the level 2 of "consultation with TKM practitioner is required". Conclusion: Based on the consensus of a seven-member expert panel of TKM gynecologists, consumption of Ginkgonis Semen (Ginkgo nut), Illici Veri Fructus (Star anise), lavender, bitter gourd, and parsley should be avoided by pregnant women. For Rosemary, Citri Unshius Pericarpium, Discoreae Rhizoma, lemongrass, Schisandrae Fructus, Cassiae Semen, Foeniculi Fructus, Mori Fructus, Cinnamomi Cortex, and Astragali Radix, the level 2 advisory may be recommended to use with caution and to consult a TKM practitioner for advice on consumption, dose, and duration.

• 대한한방부인과학회지
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• 제23권1호
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• pp.42-52
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• 2010

Purpose: This report aims to administer methodologic issues around recently conducted multicenter study for evaluating the effects of acupuncture on menopusal hot flashes and discuss practical issues for further implementation of acupuncture clinical trial for hot flashes. Methods: Study process were mentioned, and issues related to avoiding risk of bias, designing appropriate control group, optimal outcome measurement, potential different effects of menopausal status on study outcomes, and suggestions for developing future clinical trials are discussed. Results: Shortcomings of our multicenter study include lack of allocation concealment and assessor blinding, subjective outcome measurement, short-term follow-up, and fixed acupuncture regimen despite pragmatic purpose of this study. Improving trial design, using objective or validated outcomes, assessing long-term effects of acupuncture, and individualizing acupuncture regimen are needed in future clinical trials. Conclusion: We expect these practical discussions to enable researchers to plan and develop future well-designed clinical trials for evaluating the effects of acupuncture on hot flashes or other women's health issues.

• Journal of Acupuncture Research
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• 제27권1호
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• pp.51-64
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• 2010

Objectives : To introduce and compare various headache measurement tools, in order to provide fundamental information for future clinical trials and development of oriental medicine measurement tools. Methods : Eight headache assessment scales, Migraine-Specific Quality of Life Questionnaire(MQoLQ), Migraine-Specific Quality of Life(MSQOL), Migraine-Specific Quality of Life Questionnaire(MSQ), The Headache Impact Questionnaire(HImQ), Headcahe Needs Assessment Survey(HANA), Henry Ford Headache disability Inventory(HDI), Migraine Disablity Assessment Scale(MIDAS) and Headache Impact Test(HIT-6), were searched through Pubmed. General character, the process of development, verification of reliability, internal consistency, responsiveness to patient's change and validity were reviewed. Results : In assessing the quality of life of migraine patients, MQoLQ can be used to measure the change within 24 hours, MSQ and MSQOL can be used to measure the change during a relatively longer period of time. The frequency and bothersomeness of headache can be easily measured by HANA. HImQ can be used to measure the intensity of headache and the influence on normal daily activities. HDI can measure the emotional difficulties of headache patients. HIT-6 and MIDAS makes measurements possible in a short period of time, and the reliability and validity have been verified numerously. HIT-6 and MIDAS are the most frequently used measurement tools because they are simple and easy for both the assessor and the patient to understand and use. Conclusions : In this study, various headache assessment tools have been reviewed. The assessed tools were widely used after being verified for their reliability and validity. We hope this study provides fundamental information in establishing future clinical trial and clinical practice guidelines. We also hope this study to contribute to the development of an oriental medicine assessment tool for headache.

• 대한한의학회지
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• 제27권3호
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• pp.187-200
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• 2006

Objectives: Acupuncture has been applied in Asia for thousands of years, especially to rehabilitation after stroke. It has been reported that acupuncture increased cerebral blood supply and stimulated the functional activity of brain nerve cells shown by using brain imaging techniques. This study was to evaluate the effect of GB 34-GB 39 electro-acupuncture (EA) on regional cerebral blood flow (rCBF) in stroke patients and normal volunteers using single photon emission computed tomography (SPECT). Methods: The study procedure was divided into two parts: patients and volunteers studies. For the patients study, ten ischemic stroke patients (3 males, 7 females, mean age $68.5{\pm}8.9$ years old) were selected. Baseline brain SPECT was done with triple head gamma camera (MultiSPECT3, Siemens, USA) after intravenous administration of 1,110 MBq of $^{99m}Tc-ECD$. Fifteen-minute EA at GB 34 and GB 39 were applied on the affected limb. The same dose of $^{99m}Tc-ECD$ was injected during the EA, and the second set of SPECT images wasobtained. Using the computer software (ICON 7.1, Siemens, USA), 3 SPECT slices (upper, middle, lower) surrounding the brain lesion were selected and each slice was divided into 10-16 brain regions. Asymmetry indexes (AI) were analyzed in each brain region. We regarded over 10% changes of AI between before and after EA as significance. For the volunteers study, 10 healthy human volunteers (5 males, 5 females, mean age $28.1{\pm}6$ years old) were selected. In the resting state, $^{99m}Tc-ECD$ brain SPECT scans were performed. On the 7th day after the resting examination, 15 minute EA was applied at GB 34 and GB 39 on the right side of the subjects. Immediately after EA, the second SPECT images were obtained inthe same manner as the resting state. Significant increases and decreases of rCBF after EA were estimated by comparing their SPECT images with those of the resting state using paired t statistics at every voxel, which were analyzed by statistical parametric mapping with a threshold of p = 0.01, uncorrected (extent threshold: k=100 voxels). Results: In stroke patients, six of the eight (75%) had significantly increased perfusion in post-acupuncture scans compared to their baseline state. In normal volunteers, GB 34-GB GB EA increased rCBF in both hemispheres including right ventral posterior cingulate (Brodmann area (BA) 23), left superior temporal, anterior transverse temporal (BA 22, 41), left parastriate, peristriate (BA 18, 19), right occipitotemporal, angular (BA 37, 39), left rostral postcentral, caudal postcentral and preparietal (BA 2, 3, 5). However GB 34-GB 39 EA decreased rCBF in the right hemisphere including triangular and middle frontal lobes. Conclusions: The results demonstrated that OB 34-GB 39 EA increased cerebral perfusion in ischemic stroke patients and increased rCBF grossly in temporal lobes of normal volunteers. It is also suggested that there may be a correlation between the GB meridian and the territory of the middle cerebral artery.

• 대한한의학회지
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• 제29권4호
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• pp.205-212
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• 2008

Background and purpose: So far it was reported that acupuncture increased cerebral blood supply and stimulated the functional activity of brain nerve cells. A previous study demonstrated a correlation between LI4-11 electro-acupuncture (EA) and rCBF increase in frontal lobe. However, there remained a need to study further using various controls in acupuncture research. Transcutaneous electrical nerve stimulation (TENS) has been used as a non-invasive control in acupuncture study. This study was to evaluate the effect of LI4-LI11 TENS on regional cerebral blood flow (rCBF) in normal volunteers using single photon emission computed tomography (SPECT) and statistical parametric mapping (SPM). Methods: In the resting state, $^{99m}Tc-ECD$ brain SPECT scans were performed on 10 normal volunteers (9 males, 1 female, mean age 26.6$\pm$0.5 years; age range from 26 to 27 years). On the other day, 7 days after the resting examination, 15 minute TENS were applied at LI 4 and LI 11 on the right side of the subjects. Immediately after LI4-LI11 TENS, the second SPECT images were obtained in the same manner as the resting state. Significant increases and decreases of regional cerebral blood flow after LI4-LI11 TENS were estimated by comparing their SPECT images with those of the resting state using paired t statistics at every voxel, which were analyzed by statistical parametric mapping with a threshold of p = 0.001, uncorrected (extent threshold: k=100 voxels). Results: TENS applied at right LI4-LI11 increased rCBF in the left somatosensory association cortex (Brodmann area 5, 7). However there was no area where LI4-11 TENS decreased rCBF. Conclusion and suggestions: These results demonstrate that right LI4-LI11 TENS increased rCBF only in corresponding somatosensory association cortex, which was different from the previous results using LI4-11 EA. It is suggested that there be a different mechanism between TENS and EA.