• The Journal of Korean Obstetrics and Gynecology
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• v.22 no.3
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• pp.197-204
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• 2009

Purpose: Obesity is the major risk factor of the heart disease and the metabolic disease. And many obese women have dysfunction of the endocrine system. There are many reports about oriental obesity treatment program. In clinics, the electroacupuncture with exercise is believed more effective. But the difference of weight loss as exercise and women was not studied. Methods: The subjects were 75 young women who visited Kangnam Kyunghee hospital for obesity management from March 2006 to July 2008. Six treatments had performed, the weight loss checked at every treatment. 52 women treated by oriental obesity treatment with exercise, 23 women treated therapy without exercise. As the exercise and the age, the weight loss was compared. Results: The weight loss of electroacupuncture with exercise was higher than that of electroacupuncture without exercise, but was not significant. The weight loss of perimenopausal women was significantly low. Conclusion: The comparison of electroacupuncture with exercise and electroacupuncture without exercise was not significantly different. The weight loss of the older women would be less than the weight loss of the younger.

• Parasites, Hosts and Diseases
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• v.61 no.4
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• pp.418-427
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• 2023

Toxoplasma gondii infections are primarily diagnosed by serological assays, whereas molecular and fluorescence-based techniques are garnering attention for their high sensitivity in detecting these infections. Nevertheless, each detection method has its limitations. The toxoplasmosis detection capabilities of most of the currently available methods have not been evaluated under identical experimental conditions. This study aimed to assess the diagnostic potential of enzyme-linked immunosorbent assay (ELISA), real-time polymerase chain reaction (RT-PCR), immunohistochemistry (IHC), and immunofluorescence (IF) in BALB/c mice experimentally infected with various doses of T. gondii ME49. The detection of toxoplasmosis from sera and brain tissues was markedly enhanced in mice subjected to high infection doses (200 and 300 cysts) compared to those subjected to lower doses (10 and 50 cysts) for all the detection methods. Additionally, increased B1 gene expression levels and cyst sizes were observed in the brain tissues of the mice. Importantly, IHC, IF, and ELISA, but not RT-PCR, successfully detected T. gondii infections at the lowest infection dose (10 cysts) in the brain. These findings may prove beneficial while designing experimental methodologies for detecting T. gondii infections in mice.

• Proceedings of the Korean Institute of Navigation and Port Research Conference
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• 2012.06a
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• pp.388-389
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• 2012

Current offshore wind power towers are made of steel. As the capacity of wind power increases, the tower structures become higher. Steel structures have buckling problem and their increased slenderness ratios make them weak against buckling and vibration. In this study, double skinned composite tubular (DSCT) offshore wind power tower was proposed and its optimum design method was suggested. Fiber reinforced polymer (FRP) and steel were considered as material of the tubes. And both materials satisfied the required capacity.

• Journal of Sasang Constitutional Medicine
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• v.18 no.2
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• pp.125-132
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• 2006

1. Objectives The purpose of this study was to examine the regional cerebral blood-flow(r-CBF) difference between OMT(Oriental Music Therapy) group and control group using brain SPECT, to evaluate the effect of OMT in ischemic stroke patients Classified by Sasang Constitutional. 2. Methods We selected 10 ischemic storke patients, classified groups into OMT group or control group. r-CBF of two groups were examined by brain SPECT. in all group we applied SCM(Sasang constitutional medicine)treatment for 4-5 weaks, and additionally in OMT group We applied OMT for 4-5 weaks. after that all the r-CBF of two groups took brain SPECT again. r-CBF difference and change before and after SCM treatment and OMT were quantified and analyzed using SPM. 3. Results r-CBF of OMT groups were increased compared to control groups. 4. Conclusions This study demonstrated that Sasang Constitutional OMT increased regional cerebral blood perfusion to the corresponding brain areas in ischemic stroke patients.

• The Journal of Korean Obstetrics and Gynecology
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• v.33 no.2
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• pp.1-12
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• 2020

Objectives: This study was conducted to find out the optimal extraction time for Artemisia argyi. Methods: The compositional pattern was compared with HPLC (High Performance Liquid Chromatography) and GC (Gas-Chromatography) by decocting Artemisia argyi 10, 60, 120 minutes respectively. Results: With longer extraction time, the contents of reference compounds were extracted 1.1 times more when 3,4-dicaffeoylquinic acid was extracted for 60 minutes than when extracted for 10 minutes in HPLC test, but the contents were reduced when extracted for 120 minutes compared to 60 minutes extraction time. 3,4-di-O-caffeoylquinic acid, 3,5-di-O-caffeoylquinic acid, 4,5-di-O-caffeoylquinic acid, jaceosidin, and eupatilin showed the largest yield rate when extracted for 10 minutes, and it decreased as time passed. The contents of chlorogenic acid, 3,5-dicaffeoylquinic acid, 4,5-dicaffeoylquinic acid, jaceosidin, scoparone, and eupatilin were detected only in 10 minutes extraction but not in 60 or 120 minutes extraction according to GC test. Conclusions: The results show that extraction time could affect the physicochemical characteristic or composition of Artemisia argy extracted. Thus, short extraction time could be useful for decoction of Artemisia argyi.

• Journal of Korean Medicine for Obesity Research
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• v.8 no.1
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• pp.81-88
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• 2008

Objectives To investigate the relationship between Heart Rate Variability and menopause among obese middle-aged women in Korea. Subjects and Methods Forty middle-aged women (age 49.05 $\pm$ 2.64 years) with BMI > $23kg/m^2$ were recruited by local advertisement. Blood profiles of estrogen, FSH, LH, glucose, total cholesterol, HDL-cholesterol, and triglyceride were measured. Autonomic Nervous System (ANS) was estimated by short-term spectral analysis of heart rate variability (HRV). Visceral adipose tissue (VAT) and subcutaneous adipose tissue (SAT) were accessed using Computerized Tomography (CT), Bioimpedance Analysis (BIA), and anthropometry. To scrutinize the influence of ANS on obesity-related factors, we divided the subjects into pre- and post-menopausal women. Results The total cholesterol, FSH and LH were significantly higher in post-menopausal obese women group. The estradiol and standard deviation of all normal R-R intervals (SDNN), high-frequency components (HF) of the HRV were significantly lower in postmenopausal obese women group (P<0.05). Adipose tissue distribution and blood profiles were not significantly different between two groups. Conclusion Menopause induced a decrease in SDNN and HF values and increase in total cholesterol level in obese women although the VAT itself was not related with ANS in obese women.

• The Journal of Internal Korean Medicine
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• v.25 no.4
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• pp.158-166
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• 2004

Background & Object : The aim of this study was to investigate the usefulness of electrogastrography in the diagnosis field of traditional medicine through a study of the relationship between gastric motility and health condition based on oriental medicine diagnostic theory in functional dyspepsia. Method : 86 patients (male 27, female 59) with functional dyspepsia and 10 healthy control subjects (male 5, female 5) were involved in the investigation. The disease information of functional dyspepsia (based on Rome criteria II) was used for dyspeptic index and scores were obtained from the comprehensive diagnosis of Qui, Xue, Shui was applied as index for health condition, those were all investigated by questionnaire. Gastric motility were recorded and analyzed using electrogastrography in fasting and postprandial period. Results : The total score of comprehensive diagnosis of Qui Xue Shui was influenced by the number of functional dyspepsia symptoms (p=0.026). In terms of electrogastrographical parameters, both postpranial normal slow waves regularity(p=0.003) and power ratio (p=0.001) in the patients had the statistical significance and they showed an incremental inverse correlation with the number of symptoms. Dominant frequency and fasting normal slow waves regularity ratio had no statistical significance. Conclusion : Results suggest that electrogastrography is useful in evaluating the health condition of patient by comprehensive diagnosis of Qui Xue Sui.

• The Journal of Korean Obstetrics and Gynecology
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• v.36 no.3
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• pp.25-45
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• 2023

Objectives: The purpose of this study is to review the clinical research trends of ovarian cysts and to recognize the efficacy of Korean medicine intervention. Methods: Based on four domestic databases, including Korean studies Information Service System (KISS), Oriental Medicine Advanced Searching Integrated System (OASIS), Korean Medical Database (KMbase) and Research Information Sharing Service (RISS), we analyzed the case reports using Korean medicine intervention, which include acupuncture, moxibustion and herbal medicine. Data retrieval was carried out from May 12^th, to 18^th, 2022, and a total of 9 papers were included. Results: All papers were published in Korea and they contain seventeen case reports in total. The most frequently used intervention was herbal medicine, especially Gyejibokryeong-hwan-gami (桂枝茯苓丸加味), Guichulpajing-tang-gagam (歸朮破癥湯加減), Guibiondam-tang-gami (歸脾溫膽湯加味). Most cases reported statistically significant results on using Korean-medicine intervention. Also, there was no serious side effect of Korean medicine. Conclusions: In this study, we investigated the efficacy of Korean medicine intervention as an adjuvant therapy for ovarian cyst patients and research trends on ovarian cysts. Further studies are needed to supplement the safety and the evaluation of Korean medicine. However, the results should be taken cautiously as more clinical studies are needed.

• Journal of Korean Medicine for Obesity Research
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• v.8 no.1
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• pp.63-70
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• 2008

Objectives Obesity is the major risk factor of the heart disease and the metabolic disease. The autonomic nervous system is a key contributor in the regulation of energy balance, so the blunted activity may contribute to the maintenance of the obese state. So we evaluated the function of the autonomic nervous system in young overweight and obese women with heart rate variability. Methods The subjects were 26 overweight and obese young women(BMI〉$23kg/m^2$) and 25 lean women who visited Kangnam Kyunghee hospital for obesity management from March 2006 to April 2008. Bioimpedance Analysis (BIA), short-term spectral analysis of heart rate variability (HRV) were performed. Results HRV of obese young group was lower than the lean young group, but there is no statistical significance. BMI had significantly a negative correlation with Low Frequency(LF) of HRV. LF power is mediated by sympathetic nervous system activity. These results indicate a decrease of sympathetic modulation in overweight and obese young women. Conclusions Overweight and obese young women have decreased sympathetic nervous system activity. In clinical practice, an assessement of HRV would be noninvasive and sensitive methods for sympathetic nervous system of young overweight and obese women.

• Journal of Korean Medicine for Obesity Research
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• v.7 no.1
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• pp.97-106
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• 2007

Objectives : The purpose of this study was to investigate the clinical effect of oriental medical short term therapy on visceral fat obesity. In present study, we report 20-year-old visceral fat obesity woman who experienced oriental medical therapy program. Methods : The obese patient was treated from the 20th of June to the 3rd July. Herbal medicine, low calorie diet, electrolipolysis, auricular acupuncture, and aerobic exercise were done during the treatment period. Results : Her body weight decreased from 77.30kg to 71.15kg. The BMI decreased from $32.6kg/m^2$ to $29.5kg/m^2$. First of all, visceral fat tissue was effectively decreased after oriental obesity therapy evaluated by CT. Visceral fat tissue decreased from $123.44cm^2$ to $83.06cm^2$, subcutaneous fat tissue from $327.88cm^2$ to $323.09cm^2$. Short term oriental medical treatment could be effective in visceral fat obesity treatment. Conclusions : The patient with visceral fat obesity was improved using short term oriental medical treatment.