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http://dx.doi.org/10.15204/jkobgy.2020.33.2.001

The Comparative Study on Compositional Pattern Analysis of Decoction of Extracted Artemisia argyi by Different Extraction Time  

Yoon, Jun-Geol (Dept. of Clinical Korean Medicine, Graduate School, Kyung Hee University)
Kim, Mean-Sun (Choonwondang Korean Medical Clinic)
Han, Seong-Min (Choonwondang Korean Medical Clinic)
Hwang, Deok-Sang (Dept. of Korean Medicine Gynecology, College of Korean Medicine, Kyung Hee University)
Lee, Jin-Moo (Dept. of Korean Medicine Gynecology, College of Korean Medicine, Kyung Hee University)
Lee, Chang-Hoon (Dept. of Korean Medicine Gynecology, College of Korean Medicine, Kyung Hee University)
Jang, Jun-Bock (Dept. of Korean Medicine Gynecology, College of Korean Medicine, Kyung Hee University)
Publication Information
The Journal of Korean Obstetrics and Gynecology / v.33, no.2, 2020 , pp. 1-12 More about this Journal
Abstract
Objectives: This study was conducted to find out the optimal extraction time for Artemisia argyi. Methods: The compositional pattern was compared with HPLC (High Performance Liquid Chromatography) and GC (Gas-Chromatography) by decocting Artemisia argyi 10, 60, 120 minutes respectively. Results: With longer extraction time, the contents of reference compounds were extracted 1.1 times more when 3,4-dicaffeoylquinic acid was extracted for 60 minutes than when extracted for 10 minutes in HPLC test, but the contents were reduced when extracted for 120 minutes compared to 60 minutes extraction time. 3,4-di-O-caffeoylquinic acid, 3,5-di-O-caffeoylquinic acid, 4,5-di-O-caffeoylquinic acid, jaceosidin, and eupatilin showed the largest yield rate when extracted for 10 minutes, and it decreased as time passed. The contents of chlorogenic acid, 3,5-dicaffeoylquinic acid, 4,5-dicaffeoylquinic acid, jaceosidin, scoparone, and eupatilin were detected only in 10 minutes extraction but not in 60 or 120 minutes extraction according to GC test. Conclusions: The results show that extraction time could affect the physicochemical characteristic or composition of Artemisia argy extracted. Thus, short extraction time could be useful for decoction of Artemisia argyi.
Keywords
Artemisia Argyi; Extraction Time; High Performance Liquid Chromatography; Gas Chromatography;
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Times Cited By KSCI : 2  (Citation Analysis)
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