• Title/Summary/Keyword: Yonsei University

Search Result 27,522, Processing Time 0.049 seconds

BVR PHOTOMETRY OF SUPERGIANT STARS IN HOLMBERG II

  • Sohn Y.J.;Chang S.W.;Kim D.Y.;Kim J.W.;Kim S.H.;Lee J.E.;Lee J.G.;Lee J.M.;Lee M.Y.;Lee S.Y.;Lee U.S.;Park B.K.;Park H.E.
    • Journal of Astronomy and Space Sciences
    • /
    • v.23 no.1
    • /
    • pp.1-10
    • /
    • 2006
  • We report the photometric properties in BVR bands for the resolved bright supergiant stars in the dwarf galaxy Holmberg II. The color-magnitude diagrams and color-color diagram of 374 resolved stars indicate that the majority of the member stars are supergiant stars with a wide range of spectral type between B-K. A comparison with theoretical evolutionary tracks indicates that the supergiant stars in the observed field have progenitor masses between ${\sim}10M_{\bigodot}\;and\;20M_{\bigodot}$. The exponent of luminosity function in V is in good agreement with those of the Small and Large Magellanic Clouds.

Influence of Toxicologically Relevant Metals on Human Epigenetic Regulation

  • Ryu, Hyun-Wook;Lee, Dong Hoon;Won, Hye-Rim;Kim, Kyeong Hwan;Seong, Yun Jeong;Kwon, So Hee
    • Toxicological Research
    • /
    • v.31 no.1
    • /
    • pp.1-9
    • /
    • 2015
  • Environmental toxicants such as toxic metals can alter epigenetic regulatory features such as DNA methylation, histone modification, and non-coding RNA expression. Heavy metals influence gene expression by epigenetic mechanisms and by directly binding to various metal response elements in the target gene promoters. Given the role of epigenetic alterations in regulating genes, there is potential for the integration of toxic metal-induced epigenetic alterations as informative factors in the risk assessment process. Here, we focus on recent advances in understanding epigenetic changes, gene expression, and biological effects induced by toxic metals.

MR-based Partial Volume Correction for $^{18}$F-PET Data Using Hoffman Brain Phantom

  • Kim, D. H.;Kim, H. J.;H. K. Jeong;H. K. Son;W. S. Kang;H. Jung;S. I. Hong;M. Yun;Lee, J. D.
    • Proceedings of the Korean Society of Medical Physics Conference
    • /
    • 2002.09a
    • /
    • pp.322-323
    • /
    • 2002
  • Partial volume averaging effect of PET data influences on the accuracy of quantitative measurements of regional brain metabolism because spatial resolution of PET is limited. The purpose of this study was to evaluate the accuracy of partial volume correction carried out on $^{18}$ F-PET images using Hoffman brain phantom. $^{18}$ F-PET Hoffman phantom images were co-registered to MR slices of the same phantom. All the MR slices of the phantom were then segmented to be binary images. Each of these binary images was convolved in 2 dimensions with the spatial resolution of the PET. The original PET images were then divided by the smoothed binary images in slice-by-slice, voxel-by-voxel basis resulting in larger PET image volume in size. This enlarged partial volume corrected PET image volume was multiplied by original binary image volume to exclude extracortical region. The evaluation of partial volume corrected PET image volume was performed by region of interests (ROI) analysis applying ROIs, which were drawn on cortical regions of the original MR image slices, to corrected and original PET image volume. From the ROI analysis, range of regional mean values increases of partial volume corrected PET images was 4 to 14%, and average increase for all the ROIs was about 10% in this phantom study. Hoffman brain phantom study was useful for the objective evaluation of the partial volume correction method. This MR-based correction method would be applicable to patients in the. quantitative analysis of FDG-PET studies.

  • PDF

The Effect of a Video Exercise Program on Cancer-related Fatigue, Physical Function and Emotional Status in Patients with Cancer during Chemotherapy (동영상 운동프로그램이 항암 화학요법을 받는 암환자의 피로와 신체기능 및 정서상태에 미치는 효과)

  • Cho, Mee Young;Park, Ji Young;Lee, Chung Eun;Song, Su Kyung;Lee, Sun Hi;Byun, Eun Sung;Kim, Ji Youn;Park, Ok Sun;Kim, Soon Ho;Kang, Young Lynn;Han, Soo Young;Lee, Hyang Kyu;Choi, Hye Jin
    • Journal of Korean Clinical Nursing Research
    • /
    • v.18 no.3
    • /
    • pp.368-380
    • /
    • 2012
  • Purpose: The purpose of this study was to evaluate the effects of a home-based video exercise program on cancer-related fatigue, physiological and psychological status in patients with colon and rectal cancers undergoing chemotherapy. Methods: The study design was a non-equivalent control group non-synchronized design. Data were collected from patients with colo-rectal cancers in Yonsei cancer center from July 5th to October 31st in 2011. There were 40 participants; 20 in the experimental group and 20 in the control group. The structured questionnaire was used to measure fatigue, physical function and emotional status. Data were analyzed using SPSS 18.0 and a chi-squre test, Fisher's exact test, Mann-Whitney U test and Wilcoxon signed- rank test were conducted to examine the homogeneity and the research hypotheses. Results: There was a statistically significant difference in White Blood Cell count in the experimental group compared with that of the control group. The exercise group showed a slight decrease of White Blood Cell count compared with that of the control group after 4 week program (z=-2.935, p=.003). However, there were no significant differences in fatigue, physiological and psychological status between the two groups. Conclusion: In this study, the developed video exercise program was effective in markedly slightly decreasing White Blood Cell count in patients with colo-rectal cancers undergoing chemotherapy. Therefore, utilizing the video exercise program can be an useful method to promote health among patients with cancer in clinical practice.