• Journal of Life Science
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• v.13 no.6
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• pp.794-798
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• 2003

Batch production of (S)-phenyl oxirane was investigated using epoxide hydrolase activity of Rhodosporidium toruloides SJ-4. Effect of reaction condition of asymmetric biohydrolysis of racemic phenyl oxirane was analyzed and optimized by response surface methodology. The optimal conditions of pH, temperature and DMSO cosolvent ratio were 7.4, $34^P\circ}C$, and 2.3%(v/v), respectively. The final yield was enhanced up to 67%, and reaction times required to reach 99% ee (enatiomeric excess) decreased down to 50% by response surface methodology Enantiopure (S)-phenyl oxirane with 100% enantiopurity and 24% yield (theoretical yield = 50%) was obtained from racemic substrate.

• CELLMED
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• v.11 no.3
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• pp.15.1-15.9
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• 2021

The chemical constitution of a drug has been accepted as an important basis for pharmacological action in Unani medicine. Various dosage forms have been developed on this concept, such as decoctions (Joshanda), infusions (Khesanda), extract (Rub / Usara), and syrup. Zarawand Mudaharaj (ZM.) / Aristolochia rotunda L. root was subjected to extraction process using Soxhlet's apparatus by using Response Surface Methodology (RSM) to design the number of random runs of the extracts with variation in the factors of temperature, the concentration of ethanol in water, time for extraction, for optimizing and maximizing the yield concentration. The data obtained, was analyzed with regression equation and ANOVA two-way summary to interpret the interaction of the factors for yield maximization. Minitab version 18 was used to design and analyze data. Validation of the optimum conditions for maximum yield of the whole extract of ZM. Root was carried out by re-run of the extract using the optimized conditions. The maximum yield percentage thus obtained using RSM was 20.87% whereas using these optimum conditions 21.35 % yield was obtained thereby validating the method. The association between the response functions and the process variables was identified by a three-factor recorded Box-Behnken design. In the present study RSM is used because itis a cheap and affordable method to optimize maximum yield percentage which may be reliably used by researchers. The study set in the surface conditions for ZM. root extraction by the Soxhlet apparatus for maximizing the yield percentage.

• Advances in Energy Research
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• v.8 no.4
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• pp.233-241
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• 2022

Biodiesel is a non-polluting and non-toxic energy source that can replace conventional diesel. However, the higher production cost and raw material scarcity became challenges that obstruct the commercialization of biodiesel production. In the current investigation, fried cooking oil is used for biodiesel production in a hydrodynamic cavitation reactor, thus enhancing raw material availability and helping better waste oil disposal. However, due to the cavitation effect inside the reactor, the hydrodynamic cavitation reactor can give biodiesel yield above 98%. Thus, the use of orifice plates (having a different number of holes for cavitation) in the reactor shows more than 90% biodiesel yield within 10 mins of a time interval. The effects of rising temperature at different molar ratios are also investigated. The five-hole plate achieves the highest yield for a 4.5:1 molar ratio at 65℃. And the similar result is predicted by the response surface methodology model; however, the optimized yield is obtained at 60℃. The investigation will help understand the effect of hydrodynamic cavitation on biodiesel yield at different molar ratios and elevated temperatures.

• Journal of Ginseng Research
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• v.40 no.3
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• pp.229-236
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• 2016

Background: Extraction conditions greatly affect composition, as well as biological activity. Therefore, optimization is essential for maximum efficacy. Methods: Korean Red Ginseng (KRG) was extracted under different conditions and antioxidant activity, extraction yield, and ginsenoside Rg1 and phenolic content evaluated. Optimized extraction conditions were suggested using response surface methodology for maximum antioxidant activity and extraction yield. Results: Analysis of KRG extraction conditions using response surface methodology showed a good fit of experimental data as demonstrated by regression analysis. Among extraction factors, such as extraction solvent and extraction time and temperature, ethanol concentration greatly affected antioxidant activity, extraction yield, and ginsenoside Rg1 and phenolic content. The optimal conditions for maximum antioxidant activity and extraction yield were an ethanol concentration of 48.8%, an extraction time 73.3 min, and an extraction temperature of $90^{\circ}C$. The antioxidant activity and extraction yield under optimal conditions were 43.7% and 23.2% of dried KRG, respectively. Conclusion: Ethanol concentration is an important extraction factor for KRG antioxidant activity and extraction yield. Optimized extraction conditions provide useful economic advantages in KRG development for functional products.

• Journal of the Architectural Institute of Korea Structure & Construction
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• v.35 no.8
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• pp.149-156
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• 2019

In this study, dynamic responses of high - rise buildings were analyzed through the change of horizontal stiffness and yield strength among characteristics of seismic isolation system by applying middle - layer seismic isolation system to high - rise buildings of 120m height. As a result in order to prevent the displacement of the isolation layer and to control the maximum torsion angle, it is possible to appropriately control by increasing or decreasing the horizontal stiffness and the yield strength. However, depending on the maximum torsional angle and the hysteretic behavior of the seismic isolation system, excessive yield strength and horizontal stiffness increase may induce the elastic behavior of the structure and amplify the response. Therefore, it is considered that it is necessary to select the property value of the appropriate isolation device.

• KOREAN JOURNAL OF CROP SCIENCE
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• v.65 no.4
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• pp.339-345
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• 2020

Recently, abnormal weather conditions, such as extreme high temperatures and droughts, have increased in frequency due to climate change, there has accordingly been growing concern regarding the detrimental effects on field crop, including soybean. Therefore, this study was conducted to examine the effects of increased temperatures on soybean growth and yield using a temperature gradient chamber (TGC). Two major types of soybean cultivar, a medium- seed cultivar such as Daepung-2 and a large-seed cultivar such as Daechan, were used and four temperature treatments, aT+1℃ (ambient temperature+1℃), aT+2℃ (ambient temperature+2℃), aT+3℃ (ambient temperature+3℃) and aT+4℃ (ambient temperature+4℃) were established to examine the growth response and seed yield of each cultivar. Seed yield showed a higher correlation with seed weight (r=0.713***) and an increase in temperature affected seed yield by reducing the single seed weight. In particular, the seed growth rate of the large-seed cultivar (Daechan) increased at high temperature, resulting in a reduction in the number of days for full maturity. Our results accordingly indicate that large-seed cultivar, such as Daechan, is potentially vulnerable to high temperature stress. The results of this study can be used as basic data in the development of cultivation technology to reduce the damage caused by elevated temperatures. Also, further research is required to evaluate the response of each process contributing to seed yield production under high temperatures.

• Applied Chemistry for Engineering
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• v.29 no.3
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• pp.325-329
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• 2018

In this study, polyphenols were extracted from Angelica, which are known to have a high antioxidant content and the extraction process was optimized using the response surface methodology. The extraction yield and the total polyphenols were set as response values for the methodology. Quantitative factors in the extraction process were the extraction time, volume ratio of alcohol/ultrapure water, and extraction temperature. When considering both the main and interaction effects, the greatest influence factor on the extraction yield and total polyphenols was the extraction time. The optimum extraction time and temperature and alcohol/ultrapure water volume ratio for angelica were 2.8 h, $56.6^{\circ}C$ and 64.0 vol% respectively. The extraction yield and total polyphenols when using the conditions were calculated to be 24.6% and 8.76 mg GAE/g. respectively. Determination coefficients of regression equations for the extraction yield and total polyphenols were 81.4 and 75.4%, respectively. Also the overall satisfaction level was found to be 0.80 and the significance was confirmed within 5%.

• Korean Journal of Soil Science and Fertilizer
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• v.47 no.6
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• pp.571-578
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• 2014

The garlic cultivation area is moved by change of grown environment due to global warming. It is important to predict changes in cultivation area, quantity and quality of each crop. This study was carried out to estimate the yield and response of garlic growth by the rapid temperature changes in the greenhouse with thermostat control system. Seedlings of Namdo garlic were planted on September 27, 2012 and harvested on May 30, 2013. The used treatments for a rapid temperature change in March-April-May were T0 (control): $6.0-10.4-17.2^{\circ}C$, T1: $6.0-5.4(-5)-17.2^{\circ}C$, T2: $6.0-10.4-22.2(+5)^{\circ}C$ and T3: $6.0-5.4(-5)-22.2(+5)^{\circ}C$. Total dried weight per plant of garlic significantly increased by 5.0% for T2, but T1 and T3 decreased by 12.5 and 4.6%, respectively, compared to T0. Total yields of bulb within the temperature change as T2 and T0 increased significantly (p<0.05), as compared to T1. Decreasing temperature significantly (p<0.05) reduced plant height, SPAD reading, crude protein and fiber contents etc., as compared to T0 and T2. ABA contents gradually increased with time but IAA content rapidly decreased. Conclusively, growth and yield of garlic were more affected by decreased temperature than increased temperature at bulb development stage.

• KOREAN JOURNAL OF CROP SCIENCE
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• v.39 no.4
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• pp.353-358
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• 1994

Grain yields of errect-leaved corn hybrids were reported to be increased as planting density(PD) increased compared to those of horizontal leaf type hybrids. This trial was conducted to investigate the difference between errect and horizontal-leaved hybrids in response to different PD. Grain yields of both type hybrids were decreased at the highest PD, however, that of horizontal-leaved hybrid, Ga209 ${\times}$ Ki14A, was decreased more than errect-leaved hybrids which indicated varietal difference in response to PD. Responses to PD for days to tasseling, plant height, ear height, and leaf angle were not significant, also, PD ${\times}$ hybrid interactions were not observed. Yield components were decreased as PD increased and there were no PD ${\times}$ hybrid interactions for these characters. Leaf angle was negatively correlated with grain yield and yield components except for kernel weight.

• Korean Journal of Organic Agriculture
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• v.5 no.2
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• pp.93-104
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• 1997

In order to investigate the growth response of grasses to chitosan solution amended soil were studied from the standpoint of estimating the growth stimulating adequate concentrations of chitosan solution amended soil in each grass. Three species in this experiment used were orchardgrass, tall fescue and reed canarygrass. Six different concentrations of chitosan solution amended soil were 0%(control), 0.01%, 0.05%, 0.1%, 0.5% and 1.0%, respectively. The resulte obtained were as follows ; 1. Leaf area(LA), dry weight of leaf(LW), dry weight of shoot(SHW), biological yield(BY), C/f ratio and T/R ratio were significantly different between species. 2. Growth stimulating effect by chitosan solution amended soil were found in plant length(PL) and T/R ratios of grasses. 3. Adequate concentrations of chitosan solution amended soil were different between species. The highest values of yield components and dry weight of plant parts were obtained at 0.01% in orchardgrass, 0,05% in reed canarygrass and 1.0% in tall fescue, respectively. 4. The growth response of grasses to chitosan solution amended soil were different between species. Thus, an increase in leaf area(LA) and dry weight of leaf(LW) by chitosan solution amended soil was mainly contributed to increase in dry weight of shoot(SHW) and biological yield(BY) in orchardgrass. Chitosan solution amended soil also stimulated growth of shoot and increased in biological yield(BY) in tall fescue. In reed canarygrass contributed to increase in C/F ratios. 5. Adequate concentrations of chitosan solution amended soil for an economical benefit of cultivation and dry matter production of grasses were ranged from 0.01% to 0.05% levels.