• Journal of Power Electronics
• /
• v.13 no.5
• /
• pp.746-756
• /
• 2013

The modularized subunit of an electronic power transformer (EPT) is a series connection of two H-bridge voltage-source converters and a DC-DC converter with a high-frequency isolation transformer (HFIT). On the basis of cascading and paralleling the modularized subunits, EPT can be used in high-voltage and large-current applications in the power system. This paper discusses the steady state analysis of the modularized subunit of EPT. Theoretical analysis considers the influences of the two H-bridge voltage-source converters on the two sides of the DC-DC converter. We deduce the formulas of the theoretical calculation on the internal electrical characteristics of EPT (e.g., the voltages of the DC-bus capacitor and the primary side peak current of the HFIT). This paper provides guidance on the design and selection of EPT key elements (e.g., the DC-bus capacitors and HFIT). Experimental results are obtained from a single subunit of a laboratory model rated at 962 V, 15 kVA. All calculations, simulations, and experiments confirm the theoretical analysis of the subunit of EPT.

• KSII Transactions on Internet and Information Systems (TIIS)
• /
• v.12 no.3
• /
• pp.1243-1263
• /
• 2018

The two-stage linear discrimination analysis (TSLDA) is a feature extraction technique to solve the small size sample problem in the field of image recognition. The TSLDA has retained all subspace information of the between-class scatter and within-class scatter. However, the feature information in the four subspaces may not be entirely beneficial for classification, and the regularization procedure for eliminating singular metrics in TSLDA has higher time complexity. In order to address these drawbacks, this paper proposes an improved two-stage linear discriminant analysis (Improved TSLDA). The Improved TSLDA proposes a selection and compression method to extract superior feature information from the four subspaces to constitute optimal projection space, where it defines a single Fisher criterion to measure the importance of single feature vector. Meanwhile, Improved TSLDA also applies an approximation matrix method to eliminate the singular matrices and reduce its time complexity. This paper presents comparative experiments on five face databases and one handwritten digit database to validate the effectiveness of the Improved TSLDA.

• Asian Pacific Journal of Cancer Prevention
• /
• v.15 no.15
• /
• pp.5967-5976
• /
• 2014

Treating the osteosarcoma (OSA) remains a challenge. Current strategies focus on the primary tumor and have limited efficacy for metastatic OSA. A better understanding of the OSA pathogenesis may provide a rational basis for innovative treatment strategies especially for metastases. The aim of this review is to give an overview of the molecular mechanisms of OSA tumorigenesis, OSA cell proliferation, apoptosis, migration, and chemotherapy resistance, and how improved understanding might contribute to designing a better treatment target for OSA.

• Asian Pacific Journal of Cancer Prevention
• /
• v.14 no.8
• /
• pp.4599-4602
• /
• 2013

We intended to study the mechanism of the inhibitory action of curcumin on human non-small cell lung cancer A549 cell. The cell growth was determined by CCK-8 assay, and the results indicated that curcumin inhibited the cell proliferation in a concentration dependent manner. And to further confirm the relative anti-cancer mechanism of curcumin, RT-PCR was carried out to analysis the expression of relative apoptotic proteins Bax, Bcl-2. We found that curcumin could up-regulate the expression of Bax but down-regulate the expression of Bcl-2 in A549 cells. In addition, curcumin affect the mitochondrial apoptosis pathway. These results suggested that curcumin inhibited cancer cell growth through the regulation of Bcl-2/Bax and affect the mitochondrial apoptosis pathway.

• BMB Reports
• /
• v.41 no.5
• /
• pp.382-387
• /
• 2008

It is known that the stable protein 1 (SP1) detected in aspen plants remains soluble upon boiling and that sp1 expression in transgenic aspen is resistant to salt stress. Presently, we analyzed the effect of expression of SP1 in Arabidopsis thaliana plants and their response to high temperature stress. After $45^{\circ}C$ for 16 h, relative to wild type plants, sp1 transgenic plants exhibited stronger growth and were better in several physiological properties including chlorophyII, chlorophyII fluorescence, water content, proline content, and malondialdehyde content. These preliminarily results suggest that the over-expression of SP1 may notably enhance heat-tolerant level of transgenic A. thaliana plants.

• The Korean Journal of Physiology and Pharmacology
• /
• v.3 no.5
• /
• pp.461-469
• /
• 1999

Glutamate and ${\gamma}-aminobutyric$ acid (GABA) are major excitatory and inhibitory neurotransmitters in the vertebrate retina, respectively. Using the whole-cell patch clamp technique and a rapid solution changer, glutamate and GABA receptors have been extensively investigated in carp retina. Glutamate receptors on both horizontal and amacrine cells may be an AMPA preferring subtype, which predominantly consists of flop splice variants. $GABA_A$ and $GABA_C$ receptors coexist in bipolar cells and they both show significant desensitization. Kinetics analysis demonstrated that activation, deactivation and desensitization of the $GABA_C$ receptor-mediated response of these cells are overall slower than those of the $GABA_A$ response. Endogenous modulator $Zn^{2+}$ in the retina was found to differentially modulate the kinetic characteristics of the $GABA_C$ and $GABA_A$ responses.

• Korean Journal of Acupuncture
• /
• v.21 no.3
• /
• pp.159-174
• /
• 2004

Objective : The purpose of this study is to find out differences of the points locations of Dongshi-Acupuncture described in some related books. Methods : This study was carried out by means of comparing the different locational descriptions on the same acupoint in those books : Dong Shi Ji Xue Zhen Jiu Xue(董氏奇穴鍼灸學), Shi Yong Dong Shi Zhen Jiu Ji Xue Quan Ji(實用董氏鍼灸奇穴全集), Dong Shi Zhen Jiu Ji Xue Jing Yan Lu(董氏鍼灸奇穴經驗錄), Dong Shi Leng Zhen Cheng Xue Xue(동씨능침징혈학), Dong Shi Ji Xue Tu Pu Zhi Liao Xue(董氏奇穴圖譜治療學), Tai Wan Dong Shi Zhen Jiu Jing Xue Xue (台灣董氏鍼灸經穴學). Results : There are disagreement on the number, locations, cuns of acupuncture points among the books: the numbers of 11 kinds of points, locations of 2 points and cun of 15 points. Conclusions : The authors can be grouped by the opinions on the acupuncture points. One group consists of Yang Wei Jie(楊維傑), Lai Jin Xiong(賴金雄) and Hu Bing Quin(胡丙權) and Hu Wen Zhi(胡文智), Liu Jian Zhong(陸建中) and Li Guo Zheng(李國政) form the other.

• ETRI Journal
• /
• v.39 no.5
• /
• pp.756-763
• /
• 2017

A switchable single-wideband (SWB)-to-dual-wideband (DWB) bandpass filter (BPF), which is realized by using lumped switches, is presented in this paper. By alternating the operation modes-ON and OFF-in which the ON mode is achieved by placing the capacitors at the switching spots and the OFF mode is achieved by replacing the capacitors with inductors, DWB-to-SWB BPF can be achieved on the same device. In addition, by changing the capacitor values, the center frequency (CF) of the lower passband of DWB BPF can be easily tuned from 1.69 GHz to 2.22 GHz, while the higher passband stays almost unchanged. As an example, an SWB-to-DWB BPF is designed, fabricated, and measured. This BPF exhibits good performance including wideband, high isolation, compact size, and ability to switch.

• Steel and Composite Structures
• /
• v.20 no.6
• /
• pp.1323-1343
• /
• 2016

This paper presents the results of an extensive numerical analysis program devoted to the investigation of the mechanical behaviour of bolted ball-cylinder joints. The analysis program is developed by means of finite element (FE) models implemented in the non-linear code ABAQUS. The FE models have been accurately calibrated on the basis of available experimental results. It is indicated that the FE models could be used effectively to describe the mechanical performance of bolted ball-cylinder joints, including failure modes, stress distributions and load-displacement curves. Therefore, the proposed FE models could be regarded as an efficient and accurate tool to investigate the mechanical behavior of bolted ball-cylinder joints. In addition, to develop a further investigation, parametric studies were performed, varying the dimensions of hollow cylinders, rectangular tubes, convex washers and ribbed stiffener. It is found that the dimensions of hollow cylinders, rectangular tubes and ribbed stiffener influenced the mechanical behaviour of bolted ball-cylinder joints significantly. On the contrary, the effects of the dimensions of convex washers were negligible.

• International Journal of Naval Architecture and Ocean Engineering
• /
• v.9 no.1
• /
• pp.35-44
• /
• 2017

Supercavitation is one of the most attractive technologies to achieve high speed for underwater vehicles. However, the multiphase flow with high-speed around the supercavitating vehicle (SCV) is difficult to simulate accurately. In this paper, we use modified the turbulent viscosity formula in the Standard K-Epsilon (SKE) turbulent model to simulate the supercavitating flow. The numerical results of flow over several typical cavitators are in agreement with the experimental data and theoretical prediction. In the last part, a flying SCV was studied by unsteady numerical simulation. The selected computation setup corresponds to an outdoor supercavitating experiment. Only very limited experimental data was recorded due to the difficulties under the circumstance of high-speed underwater condition. However, the numerical simulation recovers the whole scenario, the results are qualitatively reasonable by comparing to the experimental observations. The drag reduction capacity of supercavitation is evaluated by comparing with a moving vehicle launching at the same speed but without supercavitation. The results show that the supercavitation reduces the drag of the vehicle dramatically.