• Title/Summary/Keyword: Y211 process

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Association of Anti-apoptotic Mechanism Due to House Dust Mite in Neutrophils with Protein Synthesis and Bad

  • Kim, In Sik;Lee, Ji-Sook
    • Biomedical Science Letters
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    • v.22 no.4
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    • pp.211-214
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    • 2016
  • House dust mite is an essential allergen in the pathogenesis of allergic diseases. Abnormal regulation of neutrophil apoptosis is an important pathogenic process in allergic diseases. In the present study, we investigated the effects of house dust mites on spontaneous apoptosis of neutrophils and its associated mechanisms. Extract of Dermatophagoides pteronissinus (DP) inhibited neutrophil apoptosis in a time-dependent manner. Cycloheximide (CHX), an inhibitor of translation, increased apoptosis of DP-treated neutrophils as well as control cells. The pro-apoptotic effect of CHX was blocked by DP in neutrophils. In addition, DP increased the phosphorylation of Bad in a time-dependent manner, indicating that it exerted an inhibitory effect on the function of Bad. These results suggest that DP has anti-apoptotic effects of neutrophils and may regulate protein synthesis and activation of Bad. Moreover, these findings may shed light on elucidation of allergy pathogenesis due to house dust mites.

Localized failure in damage dynamics

  • Do, Xuan Nam;Ibrahimbegovic, Adnan;Brancherie, Delphine
    • Coupled systems mechanics
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    • v.4 no.3
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    • pp.211-235
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    • 2015
  • In this work we present a one-dimensional damage model capable of representing the dynamic fracture for elastodamage bar with combined hardening in fracture process zone - FPZ and softening with embedded strong discontinuities. This model is compared with another one we recently introduced (Do et al. 2015) and it shows a good agreement between two models. Namely, it is indicated that strain-softening leads to a sensitivity of results on the mesh discretization. Strain tends to localization in a single element which is the smallest possible area in the finite element simulations. The strain-softening element in the middle of the bar undergoes intense deformation. Strain increases with increasing mesh refinement. Strain in elements outside the strain-softening element gradually decreases to zero.

Effects of ion-exchange for NOM removal in water treatment with ceramic membranes ultrafiltration

  • Kabsch-Korbutowicz, Malgorzata;Urbanowska, Agnieszka
    • Membrane and Water Treatment
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    • v.3 no.4
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    • pp.211-219
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    • 2012
  • To enhance the efficiency of water treatment and reduce the extent of membrane fouling, the membrane separation process is frequently preceded by other physico-chemical processes. One of them might be ion exchange. The aim of this work was to compare the efficiency of natural organic matter removal achieved with various anion-exchange resins, and to verify their potential use in water treatment prior to the ultrafiltration process involving a ceramic membrane. The use of ion exchange prior to ceramic membrane ultrafiltration enhanced final water quality. The most effective was MIEX, which removed significant amounts of the VHA, SHA and CHA fractions. Separation of uncharged fractions was poor with all the resins examined. Water pretreatment involving an ion-exchange resin failed to reduce membrane fouling, which was higher than that observed in unpretreated water. This finding is to be attributed to the uncharged NOM fractions and small resin particles that persisted in the water.

Photodegradation stability study of PVDF- and PEI-based membranes for oily wastewater treatment process

  • Ong, C.S.;Lau, W.J.;Al-anzi, B.;Ismail, A.F.
    • Membrane and Water Treatment
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    • v.8 no.3
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    • pp.211-223
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    • 2017
  • In this work, an attempt was made to compare the effects of UV irradiation on the intrinsic and separation properties of membranes made of two different polymeric materials, i.e., polyvinylidene fluoride (PVDF) and polyetherimide (PEI). The changes on membrane structural morphologies and chemical characteristics upon UV-A exposure (up to 60 h) were studied by FESEM and FTIR, respectively. It was found that cracks and fractures were detected on the PVDF-based membrane surface when the membrane was exposed directly to UV light for up to 60 h. Furthermore, the mechanical strength and thermal stability of irradiated PVDF-based membrane was reported to decrease with increasing UV exposure time. The PEI membrane surface meanwhile remained almost intact throughout the entire UV irradiation process. Filtration experiments showed that the permeate flux of UV-irradiated PVDF membrane was significantly increased from approximately 11 to $16L/m^2.h$ with increasing UV exposure time from zero to 60 h. Oil rejection meanwhile was decreased from 98 to 85%. For the PEI-based membrane, oil rejection of >97% was recorded and its overall structural integrity was marginally affected throughout the entire UV irradiation process. The findings of this work showed that the PEI-based membrane should be considered as the host for photocatalyts incorporation if the membrane was to be used for UV-assisted wastewater treatment process.

The CV Control Chart

  • Kang, Chang-W;Lee, Man-S;Hawkins, Douglas M.
    • Proceedings of the Korean Society for Quality Management Conference
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    • 2006.11a
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    • pp.211-216
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    • 2006
  • Monitoring variability is a vital part of modem statistical process control. The conventional Shewhart Rand S charts address the setting where the in-control process readings have a constant variance. In some settings, however, it is the coefficient of variation, rather than the variance, that should be constant. This paper develops a chart, equivalent to the S chart, for monitoring the coefficient of variation using rational groups of observations.

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Fabrication of a large grain YBCO bulk superconductor by homo-seeding melt growth method

  • Lee, Hee-Gyoun
    • Progress in Superconductivity and Cryogenics
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    • v.24 no.3
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    • pp.35-40
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    • 2022
  • To fabricate large grain YBCO bulk superconductors by melt process, Sm123 single crystal with a high melting point are mostly used as seeds. However, it also uses Y123 film deposited on MgO single crystal substrate. This study investigated the growth behavior of the Y123 grain during a melt process when single grain YBCO bulk was used as a seed. Single grain Y123 bulk was grown when the seed size was small. When the seed size was relatively large, multiple grains were grown but the grains were still large. Y123 seed crystal was completely decomposed during high temperature anneal at 1040℃ and new Y123 crystals were nucleated during a slow cooling stage below a peritectic temperature. Thereafter, newly formed Y123 crystals from the seed area are thought to grow into the Y1.8 powder compact. The crystallographic orientations of newly nucleated Y123 grains are independent of the crystallographic orientation of Y123 seed. It is thought that the crystallographic orientation of newly nucleated Y123 crystal can be controlled by using Y211-free Y123 single crystal as a seed of homo-seeding melt growth.

A Study on the Characteristics of the Wear Resistance Thermal Spray Coatings (내마모 용사 코팅층의 특성에 관한 연구)

  • Han Myeong Seop;Lee Sang Eok;Kim Dae Yeong
    • Proceedings of the KWS Conference
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    • v.43
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    • pp.211-212
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    • 2004
  • Characteristics of the wear resistance thermal sprayed coatings was investigated in order to determine proper coating process. Hardness evaluation and microstructural observation were conducted to find relationship between coating characteristics and its wear performance. It was found that HVOF process would give better properties than arc thermal process in terms of hardness and adhesion strength which resultantly determine wear performance of the coatings.

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Signaling Molecules at the Conceptus-Uterine Interface during Early Pregnancy in Pigs

  • Seo, Heewon;Choi, Yohan;Shim, Jangsoo;Kim, Mingoo;Ka, Hakhyun
    • Journal of Embryo Transfer
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    • v.27 no.4
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    • pp.211-221
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    • 2012
  • The process of embryo implantation requires physical contact and physiological communication between the conceptus trophectoderm and the maternal uterine endometrium. During the peri-implantation period in pigs, the conceptus undergoes significant morphological changes and secretes estrogens, the signal for maternal recognition of pregnancy. Estrogens secreted from the conceptus act on uterine epithelia to redirect $PGF_2{\alpha}$, luteolysin, secretion from the uterine vasculature to the uterine lumen to prevent luteolysis as well as to induce expression of endometrial genes that support implantation and conceptus development. In addition, conceptuses secrete cytokines, interferons, growth factors, and proteases, and in response to these signals, the uterine endometrium produces hormones, protease inhibitors, growth factors, transport proteins, adhesion molecules, lipid molecules, and calcium regulatory molecules. Coordinated interactions of these factors derived from the conceptus and the uterus play important roles in the process of implantation in pigs. To better understand mechanism of implantation process in pigs, this review provides information on signaling molecules at the conceptus-uterine interface during early pregnancy, including recently reported data reported.