• Title/Summary/Keyword: Y197-13

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Effect of Asterina pectinifera on Activities of Breast Cancer Chemopreventive and Metastatic Enzymes (별불가사리 단백추출물이 유방암예방 및 전이억제 효소계에 미치는 영향)

  • Nam, Kyung-Soo;Kim, Mee-Kyung;Cho, Hyun-Jung;Shon, Yun-Hee
    • Journal of Marine Bioscience and Biotechnology
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    • v.1 no.3
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    • pp.193-197
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    • 2006
  • The effect of protein extract from Asterina pectinifera on breast cancer chemopreventive (aromatase and cyclooxygenase-2) and metastatic (matrix metalloproteinase) enzymes was tested. Protein extract from A. pectinifera was capable of suppressing aromatase in a human placenta microsomal assay. Cyclooxygenase-2 (COX-2) activity was significantly inhibited by the protein extract from A. pectinifera at concentrations of 10, 20 and $40{\mu}g/m{\ell}$. The extract markedly reduced 12-O-tetradecanoylphorbol-13-acetate (TPA)-stimulated matrix metalloproteinase (MMP)-9 activity. These results suggest that A. pectinifera could be of therapeutic value in preventing human breast cancer.

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The Study on Supporting Situation of the Community Child Care Service for the Work-Family Balance - Focused on Dual Income Families Living in Seoul and Gyeonggi Province (일-가정 균형을 위한 지역사회의 자녀 돌봄 지원 실태에 대한 연구 -서울, 경기지역 맞벌이 가정을 중심으로)

  • Cho, Seong-Eun;Jeong, Jee-Young;Han, Ji-Sue
    • Journal of Family Resource Management and Policy Review
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    • v.13 no.1
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    • pp.147-168
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    • 2009
  • The purpose of this study is to research support systems of the community child care services for optimum work-family balance. For this purpose, the questionnaire to be completed combined four areas: the workplace, school, community and home. Then questions concerning demographic factors and community-related aspects were analysed for this article. After analyzing 197 questionnaires, supplementary questions were asked, by interview to 10 samples. Full-time working wives (eg. working from 9am to 6pm) who have 1 or more children under 10 years old, living in Seoul and Gyeonggi province were collected as samples. The results were as follows: First, child care from family and relatives, and community services was properly used during the week, but dual working parents took complete charge of child care on Saturdays. Second, emergency child care was usually provided by the family, while relatives and community child care services were used less. Third, parents spent 17% of their monthly income on total child care expenditure. Fourth, community child care services were not used often, but the level of satisfaction with them was very high. Finally, they used relatives' services for safety reasons and community services for location, and only based on informed decisions. Therefore, Saturday child care programmes need to be initiated to help physically and mentally tired parents, with more general provision of positive and diverse public support systems.

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Legal Issues and Proposed Solutions of Electronic Agents in Electronic Commerce (전자상거래에서 전자대리인의 법적 문제점과 개선방안)

  • Woo, Kwang-Myung;Cho, Hyun-Sook
    • International Commerce and Information Review
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    • v.13 no.1
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    • pp.197-216
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    • 2011
  • Computer technology has enhanced a new transaction between device or software not just between humans. It offers users agent-like functionality and becomes increasingly common. It's roles diverse from gathering informations to automated trading. However, the use of new technology challenges to traditional legal systems and makes issues in adjusting the legal systems. Contract with electronic agents makes some issues such as whether the contract is enforceable or what principle's responsibility about the operation of electronic agents is. This paper analysis these issues and provides some solutions. First of all, we should make a legal act or revise previous laws. It is better that new civil law establishes for electronic communications and approach the law of agency for attribution of the responsibility issue. Secondly, in practice, website such as shopping mall should provide the terms of conditions to bind a contract.

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Busy-tone PHY Module with IEEE 802.11 Design and Implementation in NS-2 (NS-2에서 IEEE 802.11의 Busy-tone PHY 모듈 설계 및 구현)

  • Yoo, Dae-Hun;Choi, Woong-Chul
    • Journal of the Korea Society of Computer and Information
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    • v.13 no.7
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    • pp.189-197
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    • 2008
  • ENS-2 simulator is the most widely-used simulator in the research of wired/wireless communication. Since an IEEE 802.11 module has been implemented in NS-2. much research using this module has been done for various MAC layer functions. The most important problem in terms of performance is the hidden terminal problem. To solve this problem, the solutions using a busy-tone such as BTMA, DBTMA, etc. have been proposed. In order to be able to use a busy-tone, channels using the frequency bandwidth except the frequency bandwidth of the data channel is required for the collision prevention, and a MAC layer has to be able to menage such multiple channels. In this research, we implement a module that can use a busy-tone in NS-2, implement a modified RI-BTMA by applying the implemented module, and verify its performance.

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A study on Mossbauer Spectra of the $Ni_{1-x}Cd_xFeAlO_4$ system ($Ni_{1-x}Cd_xFeAlO_4$계의 Mossbauer 스펙트럼 연구)

  • 고정대;홍성락;백승도
    • Journal of the Korean Magnetics Society
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    • v.8 no.4
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    • pp.192-197
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    • 1998
  • The Mossbauer spectra of the $Ni_{1-x}Cd_xFeAlO_4$ system were investigated with the Cd content x at room temperature. The spectra of the samples exhibit various patterns as follows 1) superparmagnetic relaxation for 0$\leq$x$\leq$0.2, 2) ferrimagnetic sextet for 0.3$\leq$x$\leq$0.5, 3) ferromagnetic relaxation for x=0.6, 0.7, 4) paramagnetic doublet for 0.8$\leq$x$\leq$1, with the Cd content x. In the samples with x values from 0 to 0.2, the substituted $Cd^{2+}$ ions transfer the $Al^{3+}$ ions from A-site to B-site mainly. The superparamagnetic relaxation effect and the ferromagnetic relaxation effect are derived from the $Al^{3+}$, $Cd^{2+}$ respectively. The magnetic structure of the $Ni_{1-x}Cd_xFeAlO_4$ system was explained by the Yafet-Kittel model.

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ARATIVE STUDY OF MAXILLARY SUPERIMPOSITION METHODS ON A LATERAL R NTGENOGRAPHIC CEPHALOMETRY (측모두부방사선사진을 이용한 상악 중첩 방법의 비교연구)

  • Jean, Young-Yim
    • Journal of the korean academy of Pediatric Dentistry
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    • v.25 no.1
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    • pp.197-208
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    • 1998
  • This study was carried out to compare the amount of the maxillary bone remodeling and tooth displacement in each three maxillary superimposition methods, Ricketts, Best-fit, Structural method. Forty cases of the lateral cephalometric radiographs from 27 boys and 13 girls who had been treated to correct anterior cross-bite were selected for the study. The initial radiographs were taken at about 8-year-old and the second radiographs were taken in about 3.3 years later. Followings were the results: 1. With the Structural method, backward movement was shown in PNS, while forward movement was observed in ANS and point A. With the Ricketts method, however, all structures were shown significant backward movement comparing with Structural method(P<0.05). With the Best-fit method, the amount of horizontal movement was similar to that of the Structural method(P>0.05). 2. The palate seemed to be moved downward with Structural method, but there was no measured downward remodeling on nasal floor with Ricketts and Best-fit method(P<0.05). 3. Comparing with Structural method, Ricketts and Best-fit method significantly underestimated the eruption of the teeth by 20% to 30% (P<0.05). 4. The Structural method showed the anteroinferior rotation (43%) and posteroinferior rotation(57%) of the palatal plane, while the Best-fit method showed mostly anterosuperior rotation(87%), but no change was found in the Ricketts method. 5. With the Structural method, there was a statistically significant correlation between the amount of the rotation of the palatal plane and that of N-S line(r=0.86). 6. The measured angles of the long axis of the incisors and molars showed no significant difference in each 3 methods(P>0.05).

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Water Environment Characteristics and Efficient Basin Management of Song Stream (송천유역의 수질환경특성 및 효율적 유역관리)

  • 허인량;신용건;이건호;최지용;김영진;정의호;정명선
    • Journal of Environmental Health Sciences
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    • v.27 no.2
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    • pp.51-59
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    • 2001
  • Song stream is located in the upstream of the Namhan River. Normal times, the stream flows down to the east sea through the drainage pipe but at rainy season, it flows to the Namhan River. There are large stock farm, leisure town and cultivated land in this basin. The pollutants from these contamination source cause eutrophication at lake Doam and deterioration of water quality in namdai stream. In this case, this study was carried out to evaluate water quality and environmental capacity as well as economical efficiency of each industry. The basin shape factor of subject stream was 0.315, slope is higher than usual basin. The BOD, T-N and T-P productive contamination loading from each contamination source was 2,690, 974 and 194 kg/day, respectively, and major contamination source was stock farm and cultivated land. Annual BOD, T-N, T-P distribution(median value) of Song stream showed 1.0~2.2 mg/L, 3.16~5.85 mg/L and 0.024~0.197 mg/L Doam lake showed 1.1~1.9, 2.51~3.89 and 0.042~0.114 mg/L, respectively. Being compared of water quality at main stream between past and present, it showed that the water quality has improved since last five years. BOD improvement rate was 8~50%. Run off loading of BOD, T-N, T-P was 366, 1129, 17.2 kg/day, and run off rate was 13.6%, 86.2%, 11.3% respectively. Finally, the result of productivity survey of each industry, leisure town, cultivated land and large stock farm was 118, 46, 50 billion won, per T-P 1kg productive, and productivity portion was 100, 39, 42% respectively, and the highest economical efficiency industry was leisure facilities.

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Verfassungsrechtliche Rechtfertigung f$\ddot{u}$r Die Kriterien bei Verteilung Knapper Medizinischer G$\ddot{u}$ter in Pandemie (감염병의 대유행에 있어서 의약품 부족 시 의약품 제공기준에 관한 헌법적 정당성)

  • Jeong, Mun-Sik
    • The Korean Society of Law and Medicine
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    • v.13 no.1
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    • pp.155-197
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    • 2012
  • Nach der sog. Neue Influenza(Schweinegrippe)-Pandemie wird die Verh$\ddot{u}$tung und Bek$\ddot{a}$mpfung von Infektionskrankheiten eine essentielle Aufgabe f$\ddot{u}$r das Gemeinwesen und stellt eine komplexe Herausforderung f$\ddot{u}$r die Rechtsordnung dar. Die n$\ddot{a}$chste Pandemie ist nicht mehr eine Frage der Ob, sondern lediglich der Zeit. Zwar ist der jetzige Influenza-Pandemie Plan und der koreanische Infektionsschutzgesetz (ISchG) nicht verfassungswidrig, weil mit ihnen die Untergrenzen des Gestaltungspielraums von Gesetzgeber nicht unterschreitet und damit die grundrechtliche Schutzpflicht von Staat nicht verletzt ist. Jedoch ist aber gesetzlicher Erg$\ddot{a}$nzung bed$\ddot{u}$rftig, denn es gibt keine konkrete Regelungen, die in einer Verknappungssituation von medizinischen G$\ddot{u}$tern bei Pandemien anwendbar sind. W$\ddot{u}$rde die Knappheit von Impfstoff nicht vermeiden, dann d$\ddot{u}$rfte dar$\ddot{u}$ber entschieden werden, wem die Ressourcen in der Verwendungskonkurrenzen bevorzugt zugeteilt werden sollen. In Knappheitssituationen ist zuerst die Frage der Verteilung medizinischer G$\ddot{u}$tern von so wesentlicher Bedeutung, dass sie von Verfassungs wegen durch das Parlament zu regeln ist. Zweitens kann die Verteilung knapper medizinischer Ressourcen auf Maximierung der Uberlebendenzahl als Menschenw$\ddot{u}$rdegrundsatz und Lebensschutzpflichten vom Staat gerichtet sein. Drittens d$\ddot{u}$rfen die in Art.11 KVerf genannte Kriteien, wie Geschlecht oder Religion, weil sie als Ungleichbehandlungskriterium im koreanischen Verfassungstext verboten sind, nicht zur Verteilung und Zuteilung herangezogen werden. Nicht zuletzt darf und muss der Gesetzgeber dar$\ddot{u}$ber regeln, wer in welchem Verfahren behandelt bzw. gesch$\ddot{u}$tzt werden soll.

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Production of Monoclonal Antibody to Chlamydia Trachomatis (Chlamydia trachomatis 진단에 유용한 단세포군 항체 생산에 관한 연구)

  • Choi, Tae-Yeal;Kim, Think-You;Kim, Choon-Won;Kim, Ki-Hong;Hwang, Eung-Soo;Cha, Chang-Yong;Kim, Kwang-Hyuk
    • The Journal of the Korean Society for Microbiology
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    • v.22 no.3
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    • pp.197-208
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    • 1987
  • Chlamydia trachomatis has now shown that this interesting intracellular parasite is a cause of nongonococcal urethritis, infantile pneumonia, pelvic inflammatory disease and epididymitis, in addition to lymphogranuloma venerum and inclusion conjunctivitis. There are several diagnostic methods for C. trachomatis, but the method using monoclonal antibody is the most sensitive and specific. The hybride cell were prepared by fusion of myeloma cell($P_3X_{63}\;Ag_8{\cdot}V_{653}$) of mouse and lymphocyte of mouse(BALB/c) that were immunized with formalin killed C. trachomatis serotype D. The cell mixtures after fusion were dispensed into 640 wells of the 96 well culture plates and continuously cultured in HAT medium for 2 weeks. The supernatants of culture media in 83(13%) wells were reacted with C. trachomatis, which were determined by enzyme-linked immunosorbent assay in 96 well microplate. The clones that secreted antibody to C. trachomatis were cloned by limiting dilution. Only six monoclones secreted antibody to C. trachomatis. The antibody titer of ascitic fluid that collected from same BALB/c mice bearing hybridoma cells was above 1:100,000. These monoclonal antibodies that were IgG reacted with elementary and reticulate bodies of all serotypes(Ba, D, E, F, G, H, J and LGV type-I) using ELISA and indirect immunofluorescence stain, but there were no cross reaction with other bacteria(coagulase negative Staphylococcus, Proteus and E. coli). We concluded these six monoclones secreted the same monoclonal antibody to C. trachomatis. The sensitivity and specificity of the monoclonal antibody compared with Microtrak(confirmatory test of C. trachomatis, Syva) was 100%, respectively.

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The Accidents Analysis for Safety Training in The Container Terminal (컨테이너터미널에서 안전교육이 사고에 미치는 영향 분석)

  • Cha, Sang-Hyun;Noh, Chang-Kyun
    • Journal of Navigation and Port Research
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    • v.40 no.4
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    • pp.197-205
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    • 2016
  • Our country, which relies on maritime transport a majority of import and export trade volume and faced with unexpected accidents, it is difficult to operate the normal function of container terminal. It also caused by reliability issue raised is likely to be given a blow to the new volumes to attract and maintain existing volumes. Under this views, the container terminal is a situation that highlights the role of the harbor workers and cope with aggressive work to provide the best quality services to customers 365 days. On these grounds, the heavy work burden is passed on to the harbor workers and caused accidents every year. The study was analyzed the safety status of the container terminal under the real following the conditions as disaster status analysis, insufficient safety training circumstances and safety training from 2012 year to 2015 in the target current K.Y terminal. As a result of equipments safety training analysis, it shows that 2012 year happened 45 cases and 31 cases in 2013 year until not practicing the training over the Gantry Crane equipment. One hand 23 cases took place in 2014 while preparation training and the other intensive training period of 2015, 8 cases occurred. it shows that 2012 year happened 13 cases and 19 cases in 2013 year until not practicing the training over the Transfer Crane equipment. One hand 12 cases took place in 2014 while preparation training and the other intensive training period of 2015, 8 cases occurred. it shows that 2012 year happened 9 cases and 9 cases in 2013 year until not practicing the training over the Yard Tractor equipment. One hand 9 cases took place in 2014 while preparation training and the other intensive training period of 2015, 4 cases occurred. Because safety training of the container terminal was given to greatly impact on the mandatory safety training, self-educational enforcement and specified equipments safety training, hence the container terminal is to strengthen the safety education to prevent accidents in advance.