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Study on the Effect of Chicken Egg Containing IgY against Helicobacter pylori (항헬리코박터 IgY 항체의 위염(위궤양) 치료효과에 관한 연구)

  • 배만종;김수정;김병기;박창호;서정일;김욱년;장태정;권상호
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.32 no.8
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    • pp.1357-1363
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    • 2003
  • This study was conducted to investigate the effect of chicken egg containing IgY against H. pylori in patients with gastritis. Sixty three H. pylori-infected volunteers (20∼43 year, Male Female=49 : 14) were randomized into four groups which were treated with one chicken egg containing IgY b.i.d. (IgY group; n=17) or omeprazole 20 mg b.i.d., amoxicillin 1.0 g b.i.d. and clarithromycin 500 mg b.i.d. (OAC group; n=17) or omeprazole 20 mg b.i.d., amoxicillin 1.0 g b.i.d., clarithromycin 500 mg b.i.d. and one chicken egg containing IgY b.i.d. (OAC with IgY group; n=16) for 2 weeks or lyophilized IgY 1 g b.i.d (lyophilized IgY group) for 1 month. $\Delta$$^{13}$ $CO_2$ before and after treatment, the eradication rate of H. pylori and histologic change including H. pylori density, acute and chronic inflammation activity, intestinal metaplasia and glandular atrophy by updated sydney system were evaluated. Eradication rate of OAC with IgY group (94%) was higher than IgY group (0%), lyophilized IgY group (0%) and OAC group (88%). $\Delta$$^{13}$ $CO_2$at 2 weeks after treatment in one patient of IgY group was decreased. But that was not changed in the other patients. $\Delta$$^{13}$ $CO_2$ at 1 week after treatment in 15 patients of OAC with IgY group was significantly lower than pretreatment level (p<0.05), and $\Delta$$^{13}$ $CO_2$ at 1 week and 2 week after treatment was decreased in the other patient. Acute inflammation activity at antrum was significantly decreased after treatment in IgY and lyophilized IgY group (p<0.01), H. pylori density at antrum was significantly decreased after treatment in IgY and lyophilized IgY group (p<0.05). Chronic inflammation activity at body was decreased after treatment in lyophilized IgY group. Intestinal metaplasia and glandular atrophy at antrum and body were not changed after treatment in IgY group. Mild intestinal metaplasia in one patient of lyophilized IgY group changed to normal after 1 month treatment. Gandular atrophy at antrum and body were not changed after treatment in lyophilized IgY group.

Calcium Intakes in Korean and American Populations (한국인과 미국인의 생애주기별 칼슘섭취 현황 비교)

  • Yu, Areum;Yang, Yoon Jung;Jeong, Sarang;Kim, Jihye;Kim, You Jin;Kwon, Oran;Oh, Se-Young;Kim, Junghyun
    • Journal of the Korean Dietetic Association
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    • v.19 no.1
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    • pp.46-58
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    • 2013
  • Calcium intake has been insufficient in all age groups in previous Korean national surveys. This study was conducted to investigate calcium intake in Korean and American populations at different ages. We analyzed two national survey data: the 2007~2009 Korean National Health and Nutrition Examination Survey (KNHANES) and the 2007~2008 National Health and Nutrition Examination Survey (NHANES). Statistically, survey procedures were applied using the weight, cluster, and strata variables. The mean calcium intake of Koreans at ages of 1~2 y, 3~5 y, 6~11 y, 12~18 y, 19~64 y, and 65+y was lower than American populations at those ages. The sufficient proportions based on Korean Estimated Average Requirement (EAR) of 1~2 y, 3~5 y, 6~11 y, 12~18 y, 19~64 y, and 65+y in Koreans were 45.5%, 33.1%, 24.3%, 16.6%, 32.7%, and 19.0%. While the sufficient rates based on American EAR of 1~3 y, 4~8 y, 9~13 y, 14~18 y, 19~30 y, 31~50 y, 51~70 y, and 71+y in US population were 88.5%, 54.4%, 35.2%, 35.8%, 55.3%, 55.2%, 40.6%, and 24.5%. Overall, the major foods contributing to calcium intakes in Koreans were milk, baechukimchi, and anchovies, whereas, milk products, pasta, or bread were major contributions to calcium in American populations. The calcium supplement intakes in the American population were 5.5 mg (1~2 y), 15.5 mg (3~5 y), 13.9 mg (6~11 y), 35.7 mg (12~18 y), 150.3 mg (19~64 y) and 334.4 mg (${\geq}65$ y). These results suggest that Korean adolescents and older adults are the most insufficient in dietary calcium intakes among Koreans. In order to accurately estimate calcium intakes in Korean populations, calcium supplements and calcium-fortified foods should be considered.

Effects of Boosting Methods of H-Y Antigen on Production Rate and Titer of H-Y Antiserum and Studies on Sexing of Rabbit Embryos by H-Y Antiserum (H-Y 항원의 Boosting 방법이 H-Y 항혈청 생산율과 역가에 미치는 효과와 H-Y 항혈청에 의한 토끼 수정란의 성판별에 관한 연구)

  • 이명섭
    • Korean Journal of Animal Reproduction
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    • v.20 no.3
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    • pp.271-278
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    • 1996
  • The present study was carried out to sex effectively mouse and rabbit embryos using rat H-Y antiserum and to improve the rate of rat producing H-Y antiserum with H-Y antibody. The H-Y antiserum was prepared from inbred SD strain female rat immunized by intrasplenic injection and subsequent intraperitioneal booster of testis cell of syngenic male newborn rat. the titer of antiserum was identified by in vitro cytotoxicity test of mouse embryos. The rabbit embryos exposed to the H-Y antiserum was classified to the developed (H-Y negative) or delayed (H-Y positive) group. The H-Y negative rabbit embryos were transferred to recipients and sex of offspring was examined. 1. When mouse embryos were exposed to the rat H-Y antisera, the ratio of embryos developed vs delayed was various. The H-Y antisera where the ratio of embryos developed vs delayed showed the range of 40~60% were recognized as having titer of H-Y antibody. 2. When the subsequent intraperitioneal boosters were followed after priming of intrasplenic injection of H-Y antigen, the rate of rat producting the H-Y antiserum with H-U antibody was 13, 27, 70 and 73% in control, 1st B, 2nd B and 3rd B, respectively. The rate in 2nd B and 3rd B was significantly(P<0.05) higher than that in control and 1st B. 3. When the rabbit morulae were exposed to the rat H-Y antiserum with H-Y antibody, the ratio of morulae developed versus delayed was 42:58% and it was close to the natural sex ratio 50:50%. It was confirmed that the rat H-Y antiserum was cross reactive to the rabbit morulae. 4. When the H-Y negative rabbit embryos were transferred to the recipients, the pregnancy rate was 50% and 83% of the newborns were females. In conclusion, the rat H-Y antiserum with high titer of H-Y antibody was able to be obtained from the female rat immunized by the intrasplenic injection followed by the second intrapent oneal booster of testis cells at a week interval. When the rabbit embryos negative to the rat H-Y antiserum were transferred, 83% of the newborns were females.

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Antimicrobial activity of Specific IgY against Streptococcus mutans (Streptococcus mutans에 대한 specific IgY의 항균력)

  • Kim, Young-Boong;Rho, Jeong-Hae;Shon, Dong-Hwa;Kim, Hee-Joo;Seong, Ki-Seung;Lee, Nam-Hyung
    • Korean Journal of Food Science and Technology
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    • v.32 no.6
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    • pp.1319-1325
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    • 2000
  • Antimicrobial effects of the specific IgY separated from eggs which were laid by hens vaccinated with Streptococcus mutans were investigated. The comparison tests of vaccination, addition levels of crude specific IgY, and innoculation concentration were applied by microscopic observation and turbidity test. Ten% addition of crude specific IgY obtained from vaccinated hens showed agglomerative clusters of S. mutans cells in supernatants and sediments, while crude IgY produced by non-vaccinated hens showed no cluster. IgY addition above 5% showed agglutinating clusters of most S. mutans cells and there was definite difference between IgY addition below 2.5% and above 5%. Concentration tests of crude IgY revealed that antimicrobial effects were differentiated by addition level and addition over 10% produced satisfactory results with turbidity test. The cluster size was dependent upon concentration of crude IgY addition. $10^5\;cfu/mL$ inoculation showed agglutinated cells and extent of agglomeration was proportional to cell numbers. Study of inoculation levels showed that 10% addition of crude IgY decreased turbidity effectively regardless of number of S. mutans cells. Plaque formation decreased to 75% with 15% addition of specific IgY concentration. These results implied that IgY separated from eggs laid by S. mutans-vaccinated hens might prevent dental caries caused by S. mutans.

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High Spatial Resolution Imaging of the Contiguous Objects Using Sub-Y-Type Interferometric Synthetic Aperture Radiometer

  • Lee Ho-Jin;Park Hyuk;Kim Sung-Hyun;Choi Jun-Ho;Seo Seung-Won;Kim Yong-Hoon;Kang Gum-Sil
    • Proceedings of the KSRS Conference
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    • 2004.10a
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    • pp.53-56
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    • 2004
  • Recently the interferometric synthetic aperture radiometer with sub-Y-type antenna array was suggested to improve the spatial resolution than that of conventional Y-type with the same number of antenna elements. The sub-Y-type performance has been reported under a point source target. In this paper, the performance of sub-Y-type is evaluated under contiguous objects. The angular resolution of sub-Y-type with 52 antennas was compared with that of Y-type with the 40 antennas. The images of sub-Y -type and Y-type array were simulated under the contiguous objects. The sub-Y-type showed higher resolution than Y-type in the simulation and experiments. The sub-Y-type has high spatial resolution than Y-type in case of contiguous source as well as single point source.

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Analysis of the direction of the canine and carnassial of small dog by 3D FEM (3차원 유한요소분석에 의한 소형견의 견치와 열육치의 교합력 방향 분석)

  • Park, yujin;Choi, sungmin
    • Journal of Technologic Dentistry
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    • v.42 no.2
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    • pp.139-145
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    • 2020
  • Purpose: This study is for the prosthesis of dog. Observed the occlusal relation between the small dog canine and carnassial teeth. The direction of the bite force was analyzed by 3D FEM(finite element method). Methods: The mandibular canine and carnassial of dog were tested. The skull of dog was contact point confirmed by dental CAD. The skull of dog was scaned using CT and a 3D model was created. The 3D model was analyzed ABAQUS. Closing movement has been 100N, 200N, 300N, 500N, 1000N, 1500N. The Direction of bite force was confirmed. Results: As occlusal force increased, the direction of bite force appeared to (-y), (-x,-y,-z), (-x,-y), (-x,-y,+z), (-x,-y,+ z), (+x,-y) in mandibular left canine. And the direction was seen at (+x, -y), (+x,-y,-z), (+x,-y), (-x,-y,+z), (-x,-y,+z), (+x,-y). When the occlusal load is 100 N, 200 N, 300 N, 500 N, the direction of the mandibular carnassial appears as (-x, -y, -z), and when the occlusal load is 1000 N, 1500 N, the direction appears as (-x,-y). Conclusion: The mandibular canine showed irregularities in the coordinates of the direction of the bite force, and the mandibular carnassial showed regularity in the coordinates of the direction of the bite force.

Flux Pinning Enhancement and Irreversibility Line of Sm doped YBCO Superconductor by Zone Melt Growth Process

  • Kim, So-Jung
    • Transactions on Electrical and Electronic Materials
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    • v.5 no.2
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    • pp.81-85
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    • 2004
  • High T$\_$c/ (Sm/Y)$\_$1.8/Ba$\_$2.4/Cu$\_$3.4/O$\_$7-$\delta$/ [(Sm/Y)] superconductor, a combination of Y and Sm(50% each), was systematically investigated by the zone melt growth process. A sample prepared by this method showed well-textured microstructure, and (Sm/Y)$_2$BaCuO$\_$5/[(Sm/Y)211]inclusions were uniformly dispersed in large (Sm/Y)Ba$_2$Cu$_3$O$\_$y/ [(Sm/Y)123]matrix. The sample showed a sharp superconducting transition at 91 K. The magnetization measurements of the (Sm/Y)1.8 sample exhibited the enhanced flux pinning, compared with Y$\_$1.8/Ba$\_$2.4/Cu$\_$3.4/O$\_$7-$\delta$/(Y1.8) sample without Sm. Critical current densities of (Sm/Y) 1.8 sample was 3.5${\times}$10$^4$A/$\textrm{cm}^2$ at 1 T and 77 K.

Factors Determining Intention to Continue Using E-HRM

  • NOERMAN, Teuku;ERLANDO, Angga;RIYANTO, Feri Dwi
    • The Journal of Asian Finance, Economics and Business
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    • v.8 no.2
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    • pp.1079-1089
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    • 2021
  • The development of information technology has promoted organizational transformation through the utilization of an electronic information system. This research aimed to identify factors that influence continuous intention to use E-HRM. This empirical research applies the Technology Acceptance Model and Cognitive Model for identifying significantly impacted areas of continuous intention to use E-HRM in a highly dynamic environment. The data were collected using questionnaires delivered directly to respondents. The sample was 100 employees of ESQ Group selected through random sampling. The variables used were subjective norms (X1), perceived behavioral control (X2), perceived innovativeness (Y1), cognitive absorption (Y2), satisfaction (Y3), and continuous intention to use E-HRM (Y4). Statistical analysis using Structural Equation Modelling (SEM) with Smart PLS was applied. The results revealed that behavioral control (X2) did not influence the continuous intention to use E-HRM (Y4) and that cognitive absorption (Y2) and satisfaction (Y3) did not significantly influence continuous intention to use E-HRM (Y4). Subjective norms (X1) significantly influenced both perceived innovativeness (Y1) and continuous intention to use E-HRM (Y4), perceived behavioral control (X2) significantly influenced both perceived innovativeness (Y1) and cognitive absorption (Y2), and perceived innovativeness (Y1) significantly influenced both satisfaction (Y3) and continuous intention to use E-HRM (Y4).

FUZZY STABILITY OF A CUBIC-QUARTIC FUNCTIONAL EQUATION: A FIXED POINT APPROACH

  • Jang, Sun-Young;Park, Choon-Kil;Shin, Dong-Yun
    • Bulletin of the Korean Mathematical Society
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    • v.48 no.3
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    • pp.491-503
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    • 2011
  • Using the fixed point method, we prove the generalized Hyers-Ulam stability of the following cubic-quartic functional equation (0.1) f(2x + y) + f(2x - y) = 3f(x + y) + f(-x - y) + 3f(x - y) + f(y - x) + 18f(x) + 6f(-x) - 3f(y) - 3f(-y) in fuzzy Banach spaces.

BOUNDEDNESS IN NONLINEAR PERTURBED DIFFERENTIAL SYSTEMS VIA t-SIMILARITY

  • Im, Dong Man;Goo, Yoon Hoe
    • Korean Journal of Mathematics
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    • v.24 no.4
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    • pp.723-736
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    • 2016
  • This paper shows that the solutions to nonlinear perturbed differential system $$y^{\prime}= f(t,y)+{\int_{t_{0}}^{t}g(s,y(s))ds+h(t,y(t),Ty(t))$$ have bounded properties. To show the bounded properties, we impose conditions on the perturbed part ${\int_{t_{0}}^{t}g(s,y(s))ds,\;h(t, y(t),\;Ty(t))$, and on the fundamental matrix of the unperturbed system y' = f(t, y) using the notion of h-stability.