• 대한한의진단학회지
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• 제10권1호
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• pp.1-35
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• 2006

Background and purpose: Giu Ga Chu Yo(診家樞要) was written in the year 1359 by Hwal Su(滑壽) who was a famous oriental doctor between Won(元) and Myeong(明) dynasty. As specialized in sphygmology (脈學), this book was brought together most things about sphygmology(脈擧) before Won(元) dynasty by e author. Moreover he added the self-realized things to this book. Methods: In this book, besides a author's preface, there are all 20 chapters which are Chu Yo Hyeon Eon(權要玄言), Jwa U Su Bae Jang Bu Bu Wi(左右手配臟腑部位), O Jang(五臟), Sa Si Peong Maek(四時平脈), Nae Gyeong Sam Bu Maek Beop(內經三部脈法), Ho Heup Chim Bu Jeong O Jang Beop(呼吸沈浮定五臟法), In Ji Ha Gyeong Jung I Jeing O Jang Beop(因指下重以定五腑法), Sam Bu So Ju(三部所主), Ji Maek Su Beop(持脈手法), Maek Gwi Yu Sin(脈貴有神), Maek Eum Yang Yu Seong(脈陰陽類成), Gyeom Hyeon Maek Ryu(兼見脈類), Je Maek Ui Gi Ryu(諾脈宜忌類), Heom Je Sa Jeung Ryu(驗諸死症類), Sa Jeol Maek Ryu(死絶脈類), O Jang Dong Ji Maek(五藏動止脈), Bu In Maek Beop(婦人脈法), So A Mrek Beop(小兒脈法), Maek Sang Tong Hoe(脈象統會), Maek Sang Ga(脈象歌) and an epilogue in the end. Result and Conclusion: Looking into this book, we can know that it is very detail in analyzing item by item, bright and simple in explaining and it is very useful in studying pulse evaluation(脈診). In his preface, Hwal Su(辨壽) expresses his opinion with firm confidence that 'Do(道) of the World scattered in several scholarships and books of method and technique(術). Nothing of method and technique(力術) is more important than medicine. Nothing of medicine goes before pulse evaluation(脈診).' With such good reasons, as a student of sphygmology(脈學), I think this book is very valuable in studying pulse evaluation.' So I add Hangul suffixes(吐) to a part of this book and translate it into Korean.

• 한국진공학회:학술대회논문집
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• 한국진공학회 2013년도 제45회 하계 정기학술대회 초록집
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• pp.182.1-182.1
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• 2013

Silver (Ag)는 높은 반사율을 가지고 있어 Top-Emission Organic Light Emitting Diode (T-OLED)의 반사전극으로 사용하기 적합하지만 일함수가 낮은 단점 (4.3 eV)을 가지고 있다. 이런 낮은 일함수를 증가시키기 위하여 Ag 박막 표면을 산화시켜 일함수를 증가시키기 위한 연구가 진행중에 있으며, 이 연구에서는 UV로 $O_3$을 발생시켜 Ag 박막 표면을 산화시키기 위한 연구를 진행하였다. 특히, Ag 박막 표면의 일함수 변화를 측정하기 위하여 SPM (Scanning Probe Microscopy)의 KPFM (Kelvin Probe Force Microscopy) mode를 적용하여 nano 영역에서의 일함수 변화를 surface potential로 측정하여 UV 표면 산화에 의한 표면 일함수 형상을 확인하였다. Ag 박막은 rf magnetron sputter를 사용하여, Si 기판위에 300nm 두께로 증착시켰다. 이후 $O_3$ 발생되는 UV 램프로 Ag 박막 표면 30초 간격으로 최대 5분간 산화시켰으며, 이후 KPFM mode를 사용하여 산화 시간에 따른 Ag 박막 표면의 potential 변화를 측정하였다. 0~3분간 산화된 Ag 박막 표면의 potential은 약 6 mV로 일정하였으나 3분 이후 최대 110 mV까지 급격하게 변화하는 것을 확인할 수 있었다. Ag 박막 표면의 RMS roughness는 UV 산화처리 전0.7 nm였으나, potential이 급격하게 증가하는 시점인 3분 이후 2.83 nm로 약 400% 이상 증가하였다. 이를 통해 $O_3$ 발생 UV 램프로 산화된 Ag 박막의 표면 물성은 처리 시간에 따라 급격히 변하는 것을 확인하였다.

• 생명과학회지
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• 제25권6호
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• pp.673-679
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• 2015

본 연구에서는 재비늘버섯(Pholiota highlandensis)의 리그닌 분해 활성을 확인하고, laccase 생산을 위한 최적 배양 조건을 조사하였다. 재비늘버섯 균사체로부터 laccase를 생산하기 위한 배지조건을 조사한 결과, 다양한 합성 배지 중에서 Coriolus versicolor 배지(2% dextrose, 0.4% peptone, 0.6% yeast extract, 0.046% KH₂PO₄, 0.1% K₂HPO₄, 0.05% MgSO₄·7H₂O)가 가장 높은 laccase 활성을 나타내었다. Laccase생산에 대한 배양 조건을 최적화하기 위하여 Coriolus versicolor 배지의 조성 중에서 탄소원, 질소원, 인산원, 무기염에 대한 영향을 조사하였다. 탄소원, 질소원, 인산원, 무기염은 각각 2% fructose, 0.4% peptone 및 0.6% yeast extract, 0.05% NaH₂PO₄, 0.05% MgSO₄·7H₂O의 경우에 가장 높은 효소활성을 나타내었다. 본 균주는 몇 가지 방향족 화합물에 의해 laccase 생산이 유도되었고, guaiacol을 첨가할 경우 25℃에서 11일 동안 배양하였을 때 효소의 활성이 최대치(114.1 U/ml)에 도달하였다. 또한 본 균주의 laccase 생산을 위한 최적 pH와 온도는 각각 8.0과 35℃를 나타내었다. 최적 조건에서 배양된 균사체 배양 상등액을 Native-PAGE로 전기영동한 후 ABTS를 기질로 사용하여 활성염색을 수행한 결과, 약 90 kDa 부근에서 laccase 활성을 가지는 1개의 밴드를 확인하였다.

• 한국진공학회:학술대회논문집
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• 한국진공학회 2011년도 제40회 동계학술대회 초록집
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• pp.119-120
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• 2011

Kawazoe는 1997년 p-type TOS를 만들기 위해서는 3가지가 충족되어야 한다고 언급한바 있다. 첫 번째, 가시광영역에서 투명하기 위해서 cation의 d10s0이 가득 차야 한다. 가득 차지 않은 d10 shell은 광 흡수가 가능하여 투과도를 떨어뜨린다. N-type을 예로 들어 ZnO, TiO, In2O3가 각각 Zn2+, Ti4+, In3+가 되어 d shell을 가득 차게 만드는 것을 볼 수 있다. 두 번째, cation d10s0 shell은 산소의 2p shell과 overlap 되어야 한다. 이 valence band는 홀 전도를 더욱 좋게 한다. 예를 들어 Cu1+(3d), Ag1+(4d)가 해당한다. 세 번째로, 양이온과 산소간의 공유결합을 강하게 하기 위해서 결정학적 구조는 매우 중요하다. Delafossite 구조는 산소가 pseudo-tetrahedral 구조로서 공유결합에 유리하다. 이러한 환경은 O2- (2p6)을 형성하고 홀의 이동도를 증가시킨다. 예를 들어 Cu2O의 경우 앞의 2가지를 만족시키지만 광학적 특성에서 좋지 않다. 그 이유가 3번째 언급한 결정학적인 요인에 있다. 결정 계의 환경은 Cu2O를 따라가면서 3차원적인 연결을 2차원적으로 변형된 delafossite 구조에서는 quantum well이 형성되어 band gap이 커진다. 본 연구에서는 전기적 이방성을 가지고 있는 delafossite CuCrO2 상에서 우선배향을 일으키는 인자 중 기판을 변화시켜 실험을 진행하였다. 결과적으로 기판변화를 통해 우선배향조절이 가능하였으며 CuCrO2 박막을 시켰으며, 결정방향에 따른 전기적 물성의 이방성에 관한 연구는 계속 진행 중에 있다. c-plane sapphire 기판위에는 [00l]로 성장하는 반면, c-plane STO 기판 위에는 [015] 방향으로 성장하는 것을 확인하였다. 이러한 원인은 기판과 증착되는 박막간의 mismatch를 최소화 하여 strain을 줄이고, 계면에서의 Broken boning 수를 줄여 계면에너지를 낮추는 방법이기 때문일 것으로 예상된다. C-plane sapphire 기판위에 증착될 경우 증착온도가 증가함에 따라 c-축으로의 성장이 온전해지며 이에 따라 캐리어농도의 감소와 모빌리티의 증가가 급격하게 변하는 것을 확인할 수 있다. 반면 c-plane STO 기판에서는 증착온도에 따른 박막의 배향변화가 없으며 전기적 물성 변화 또한 비교적 작은 것을 간접적으로 확인하였다.

• 대한한의진단학회지
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• 제9권2호
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• pp.25-56
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• 2005

Background and purpose: Gin Ga Chu Yo(診家樞要) was written in the year 1359 by Hwal Su(滑壽) who was a famous oriental doctor between Won(元) and Myeong(明) dynasty. As specialized in sphygmology(脈學), this book was brought together most things about sphygmology(脈學) before Won(元) dynasty by the author. Moreover he added the self-realized things to this book. Methods: In this book, besides a author's preface, there are all 20 chapters which are Chu Yo Hyeon Eon(樞要玄言), Jwa U Su Bae Jang Bu Bu Wi(左右手配臟腑部位), O Jang(五臟), Sa Si peong Maek(四時平脈), Nae Gyeong Sam Bu Maek Beop(內經三部脈法), Ho Heup Chim Bu Jeong O Jang Beop(呼吸沈浮定五臟法), In Ji Ha Gyeong Jung I Jeong 0 Jang Beop(因指下輕重以定五臟法), Sam Bu So Ju(三部所主), Ji Maek Su Beop(持脈手法), Maek Gwi Yu Sin(脈貴有神), Maek Eum Yang Yu Seong(脈陰陽類成), Gyeom Hyeon Maek Ryu(兼見脈類), Je Maek Ui Gi Ryu(諸脈宜忌類), Heom Je Sa Jeung Ryu(驗諸死症類), Sa Jeol Maek Ryu(死絶脈類), O Jang Dong Ji Maek(五藏動止脈), Bu In Maek Beop(婦人脈法), So A Maek Beop(小兒脈法), Maek Sang Tong Hoe(脈象統會), Maek Sang Ga(脈象歌) and an epilogue in the end. Result and Conclusion: Looking into this book, we can know that it is very detail in analyzing item by item, bright and simple in explaining and it is very useful in studying pulse evaluation(脈診). In his preface, Hwal Su(滑壽) expresses his opinion with firm confidence that ‘Do(道) of the World scattered in several scholarships and books of method and technique(方術). Nothing of method and technique(方術) is more important than medicine. Nothing of medicine goes before pulse evaluation(脈診).’ With such good reasons, as a student of sphygmology(脈學), I think this book is very valuable in studying pulse evaluation. So I add Hangul suffixes(吐) to a part of this book and translate it into Korean.

• International Journal of Oral Biology
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• 제35권2호
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• pp.61-67
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• 2010

Selenoprotein S (SelS) is widely expressed in diverse tissues where it localizes in the plasma membrane and endoplasmic reticulum. We studied the potential function of SelS in erythrocyte differentiation using K562 cells stably over-expressing SelS wild-type (WT) or one of two SelS point mutants, $U_{188}S$ or $U_{188}C$. We found that in the K562 cells treated with $1\;{\mu}M$ Ara-C, SelS gradually declined over five days of treatment. On day 4, intracellular ROS levels were higher in cells expressing SelS-WT than in those expressing a SelS mutant. Moreover, the cell cycle patterns in cells expressing SelS-WT or $U_{188}C$ were similar to the controls. The expression and activation of SIRT1 were also reduced during K562 differentiation. Cells expressing SelS-WT showed elevated SIRT1 expression and activation (phosphorylation), as well as higher levels of FoxO3a expression. SIRT1 activation was diminished slightly in cells expressing SelS-WT after treatment with the ROS scavenger NAC (12 mM), but not in those expressing a SelS mutant. After four days of Ara-C treatment, SelS-WT-expressing cells showed elevated transcription of $\beta$-globin, $\gamma$-globin, $\varepsilon$-globin, GATA-1 and zfpm-1, whereas cells expressing a SelS mutant did not. These results suggest that the suppression of SelS acts as a trigger for proerythrocyte differentiation via the ROS-mediated downregulation of SIRT1.

• 한국중재학회지:중재연구
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• 제14권1호
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• pp.345-376
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• 2004

Die staatliche Gerichtsbarkeit und die Schiedsgerichtsbarkeit haben es gemeinsam, dass sie eine Institution der Entscheidung von priyatrechtlichen Streitigkeiten sind und dass ihre Entscheidungen auf ein rechtmaessiges Verfahren beruhen muessen. Auf der anderen Seite aber unterscheiden sick die beiden Institutionen wesentlich dadurch, dass die Schiedsgerichtsbarkeit auf einer rechtsgesch$\"{a}$ftlichen Parteihandlung, n$\"{a}$imlich einer Schiedsvereinbarung beruht, w$\"{a}$hrend das Prozessvefahren vol den staatllchen Gerichten seine Legitimation in der Staatshoheit hat. Wegen der vertraglichen Basis der Schiedsgerichtsbarkeit k$\"{o}$nnen die Parteien in der Schiedsgerichtsbarkeit $\"{u}$ber das Verfahren verf$\"{u}$gen, und beim Fehlen der Parteivereinbarung f$\"{u}$hrt das Schiedsgericht nach freiem Ermessen das Verfahren durch. Damit das Schiedsvefahren nicht zu einem quasi-Konventionalprozess wird und die Garantie der rechtsstaatlichen Prinzipien nicht ausser acht gelassen wird und ein geordnetes Schiedsverfahren zu gewahrleisten ist, braucht das Schiedsgericht einen Massstab seines Ermessens. Die Regelungen der Zivilprozessordnung sind dabei in erster Lime in Erw$\"{a}$gung zu ziehen, weil sie sick auf die rechtm$\"{a}$ssige Erledigung der Streitigkeiten richten. Die Zivilprozessordnung hat nicht zuletzt einen grossen Einfluss auf das Schiedsverfahren, sei os durch die Ausiibung der Zwangsgewalt des staatlichen Gerichts bei der Beweisaufnahme odor sei es durch das Anerkennungs- und Vollstreckbarerklarungsverfahren des Schiedsspruchs. Obwohl der Zivilprozess md das Schiedsverfahren sich im wesentlichen unterscheiden lassen, sind sie miteinander eng verbunden. Die staatlichen Gerichte haben nicht nor die Pflicht, im Wege der Aufhebungsklage md des YollstreckbarerldErungsverfahrens die Schiedsgerichtsbarkeit zu kontrollieren, sondern auch die Aufgabe, bei der Entscheidung des Schiedsgerichts mitzuwirken. Die Schiedsgerichtsbarkeit ist vol allem bei der Beweisaufnahme auf dieMitwirkung des staatlichen Gerichts angewiesen. Das ergibt sich aus dom Gewaltmonopol des Staates. Bei der Mitwirkung des staatlichen Gerichts spielt die Zivilprozessordnung eine entscheidende Rolle, weil das Gericht die Beweisaufnahme nach der Zivilprozessordnung durchzufiihren hat. Fiir die anderung der Zivilprozessordnung im Jahr 2002 muss man daher auch in der Schiedsgrichtsbarkeit Aufrnerksarnkeit zeigen. Vor allem lassen sich die eventuelle, alternative subjektive Klagenhaufung, die Rechtzeitigkeit des Vorbinggens, die St$\"{a}$rkung der Vorbereitung der miindlichen Verhandlung, der Zeugenbeweis md die Vorlegungspflicht der Urkunden sowie die Abanderungslrlage auch auf das Schiedsverfahren anwenden nd damit kann man die EffektivitEt des SchiedsverfEhrens vertiefen und erh$\"{o}$hen.

• 동의생리병리학회지
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• 제22권6호
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• pp.1431-1438
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• 2008

The marine algae, Padina arborescens, have been used traditionally for treatment of various brain diseases. However, the molecular studies on the effect of Padina arborescens have not been carried out. In the present study, the protective effect of the water extract of Padina arborescens (PAWE) was researched in $H_2O_2$-treated human vascular endothelial cells, ECV304. ECV304 cells were pre-incubated with PAWE (0, 400, 800, 1,200 and $1,600{\mu}g/m{\ell}$) for 12 h and treated with 500 uM $H_2O_2$ for 12 h, and then the protective effects of PAWE were determined. PAWE recovered the $H_2O_2$-induced cell damage and decreased ROS production in ECV304 cells. Moreover, PAWE increased ERK expression and inhibited p38 and JNK expression. Furthermore, PAWE dosedependently increased the expression of heme oxygenase-1 (HO-1) and the HO-1 expression was reduced by ERK inhibitor treatment in $H_2O_2$-treated EVC304 cells. These results suggested that protective effect of PAWE on $H_2O_2$-induced oxidative stress in ECV304 cells might be associated with the production of HO-1 through the ERK signal pathway.

• Toxicological Research
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• 제22권4호
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• pp.391-395
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• 2006

Flavonoids are polyphenolic compounds that are ubiquitous in plants. They have been shown to possess a variety of biological activities, such as antioxidant and anticancer. Reactive oxygen species (ROS) lead to damages of cellular molecules and it is the one of various factors to induce cancer. The one of flavonoids, Luteolin, was found to scavenge 1,1-diphenyl-2-piculhydrazyl (DPPH) radical and intracellular reactive oxygen species (ROS). Moreover luteolin showed protection on hamster lung fibroblast cells (V79-4 cell) damage induced by $H_2O_2$. And then it was investigated whether it may show cytotoxicity effect against various cancer cells by MTT, Luteolin at $10{\mu}g/ml$ showed the cell viability of 63.2%, 34.7%, 18.4% and 71.4% against NCl-H460, HeLa, U937 and MCF-7, respectively. As a result, luteolin shows more sensitive to U937 cells among the tested cancer cell lines. In summary, luteolin has antioxidant and cytotoxicity effect or various cancer cell lines.

• 한국전기전자재료학회:학술대회논문집
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• 한국전기전자재료학회 2008년도 하계학술대회 논문집 Vol.9
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• pp.53-53
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• 2008

Piezoelectric transformers have been widely used such as DC-DC convertor, invertor, Ballast, etc. Because, the y have some merits compared with electro-magnetic transformers such as step-up ratio, high efficiency, small size and lg hit weight, etc. Piezoelectric transformer require high electromechanical coupling factor kp in order to induce a large out put power in proportional to applied electric field. And also, high mechanical quality factor Qm is required to prevent mechanical loss and heat generation. In general, PZT system ceramics should be sintered at high temperatures between 1200 and $1300^{\circ}C$ in order to obtain complete densification. Accordingly, environmental pollution due to its PbO evaporation. Hence, to reduce its sintering temperature, various kinds of material processing methods such as hot pressing, high energy mill, liquid phase sintering, and using ultra fine powder have been performed. Among these methods, liquid phase sintering is basically an effective method for aiding densification at low temperature. In this study, In order to comparis on low temperature sintering and solid state sintering piezoelectric transformers, rosen type transformers were fabricated u sing two PZT ceramics compositions and their electrical properties were investigated.