• Journal of Environmental Health Sciences
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• v.34 no.6
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• pp.452-458
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• 2008

This study was undertaken to establish the biological reaction characteristics of the marine products industry wastewater which contains high concentrations of organic matter and saline. As the S/I is varied from 0.3 to 1.2, the results were follows : the observed ultimate anaerobic biodegradability varied from 72.0 to 88.0%, the first order reaction rate varied from 0.1735 to $0.3420\;day^{-1}$ and the second order reaction rate varied from 0.0132 to $0.0295\;day^{-1}$. When S/I was 0.9, the first order reaction rate had a maximum value, but the variations of the second order reaction rate were less than 1st-order reaction rate. When the operation time exceeded 2 days the gas production rapidly increased. The source of this rapid increase was due to that the activity of the granular sludge used in this study being faster than that of conventional sludge. Under aerobic condition, the characteristics of organic matter were as follows: the marine industry wastewater used in this study contained about 81% of biodegradable matter, and it was divided into readily biodegradable COD(Ss), slowly biodegradable COD(Xs), soluble COD(Si) and inert suspended COD (Xi). The percentages of each COD were 87.3%, 23.9%, 6.4% and 12.4% respectively.

• The Journal of Korean Medicine
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• v.23 no.4
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• pp.140-150
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• 2002

Objectives: The water extract of Omija-tang (OMIT) has traditionally been used for treatment of ischemic heart and brain damage in oriental medicine. However, little is known about the mechanism by which the water extract of OMJT rescues cells from these damages. Therefore, this study was designed to investigate the protective mechanisms of OMJT on oxidative stress-induced toxicity in H9c2 cardiomyoblast cells. Methods: Treatments of $H_2O_2$, or $ZnC_{12}$ markedly induced death of H9c2 cardiomyoblast cells in a dose-dependent manner. The characteristics of oxidative stress-induced death of H9c2 showed apparent apoptotic features such as DNA fragmentation. OMJT significantly reduced both ${H_2O_2}-induced$ cell death and chromatin fragmentation. The decrease of B치-XL expression by $H_2O_2$ were inhibited by OMJT. In addition, the increase of Bcl-XS expression was also inhibited by OMJT. In particular, Fas expression, which is generally recognized as cell death-inducing signal by Fas/FasL interaction, was markedly increased by H2O2 in a time-dependent manner. Also, the expression profile of proteins in Chang cells were screened by using two-dimensional (2-D) gel electrophoresis. Among 300 spots resolved in 2-D gels; the comparison of control versus apoptotis cells revealed that signal intensity of 6 spots decreased and 11 spots increased. Results and Conclusions: Taken together, this study suggests that the protective effects of the water extract of OMJT against oxidative damages may be mediated by the modulation of Bcl-XL/S Fas expression.

• The Journal of Korean Medicine
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• v.25 no.3
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• pp.149-159
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• 2004

Backgrounds & Objectives : The water extract of Gyungokgo (GOG) has traditionally been used for treatment of general weakness and hemoptysis in oriental medicine. However, little is known about the mechanism by which the water extract of GOG rescues cells from these damages. This study was designed to investigate the protective mechanisms of GOG on H2O2­induced cell death in H9c2 cardiomyoblasts. Methods : In this study, we used H9c2 cells. Cells were treated with oxidative stress in the absence and presence of 1000㎍/ml GOG for 12hrs. Cells were treated with various concentrations of GOG for 12hrs. Cell viability was measured by MTT assay. Oxidative stress, which markedly decreased the viability of H9c2 cells, was characterized by apparent apoptotic features such as chromatin condensation as well as fragmentation of genomic DNA and nuclei. Results : GOG significantly reduced H₂O₂-induced cell death and apoptotic characteristics. The cotreatment of GOG and H₂O₂ in H9c2 cells also induced the phosphorylation of ERKs in a time-dependent manner. Moreover, PD098059, a MEK1 (upstream activator of ERK) inhibitor attenuated the protective effect of GOG on H₂O₂-induced cytotoxicity in H9c2 cardiomyoblast cells. Conclusions : These results suggest that MEK/ERK pathways play important roles in the protective effects of GOG in H9c2 cells. Taken together, they suggest that the protective effects of the water extracts of GOG against oxidative damages may be mediated by the regulation of HO-1, Fas/FasL and Bcl-XS proteins.

• 한국해양학회지
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• v.30 no.4
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• pp.288-301
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• 1995

Rates of the sedimentation and particle mixing have been estimated by applying uranium-series disequilibrium techniques to three sediment cores collected from the korea Deep Ocean Study (KODOS) site between the clarion and Clipperton Fracture Zones (CCFZ) of the Equatorial Pacific. Sedimentation rates based on the profiles of excess /SUP 230/Th activity and /SUP 230/ Th/SUB xs//SUP 232/ Th activity ratios at the southeastern part of the study area were estimated to be in the order of a few millimeters per thousand year, while at the northwestern part a factor of ten lower. Excess activities of /SUP 230/Th and /SUP 230/Th ratios showed intervals of constant values in the upper part of the sediment cores, probably generated by biological particle mixing. A "two-box" advection-diffusion steady state mixing model was employed in order to estimate particle mixing rates in the upper and the lower layers, based on the distribution profiles of excess /SUP 210/Pb activities. Particle mixing coefficients were estimated to be in the order of 10$^1$ cm$^2$/y in the upper layer and 10/SUP -1/-10/SUP 0/ cm$^2$/y in the lower layer.

• Proceedings of the Korean Society of Applied Pharmacology
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• 1993.04a
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• pp.73-73
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• 1993

As part of a research program to develope 3rd generation anti tumor platinum complexes, a series of platinum complexes which have 4, 5-bis-(aminomethyl)- 1, 3-dioxolane derivatives as bidenate amine ligands, represented by the general structual formula was prepared. The R$_1$ and/or R$_2$ substituents in this series of platinum complexes can be hydrogen. alkyl, of jointly formed cyclohexane. Two Xs can be a bidenate leaving ligand such as 1, 1-cyclobutanedicarboxylate, malonate, dimethylmalonate, ethylmalonate, glycolate, L-lactate, or N-methyliminodiacetate. From based on the pharmacological and toxicological studies, we have chosen SKI 2053R, cis-malonato[(4R, 5R)-4, 5-bis(aminomethyl)-2-isopropyl-1, 3-dioxolane] platinum(II) complex (NSC D644591) as a candidate for clinical evaluation. The antitumor activity of a new anti tumor platinum complex, cis-malonato [(4R, 5R)-4, 5-bis(aminomethyl)-2-isopropyl-1, 3-dioxolane] platinum(II) (SKI 2053R, NSC D644591), was compared with those of cisplatin and carboplatin using murine tumors. We evaluated three platinum complexes against L1210/CPR, a subline of L1210 leukemia resistant to cisplatin for their abilities to overcome tumor resistance to cisplatin. The in vitro cytotoxicity of SKI 2053R to L1210 cell line was 2.5-fold less potent thann that of cisplatin, and was 10-fold more cytotoxic than that of carboplatin. SKI 2053R retained similar cytotoxic effect and anti tumor activity to L1210/CPR cell line, like the cytotoxicity of SKI 2053R to L1210 cell line, while either cisplatin or carboplatin had not property to overcome the acquired cisplatin-resistance. SKI 2053R exhibited greater or comparable antitumor activity than cisplatin or carboplatin in murine tumor models.

• Journal of Digital Convergence
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• v.13 no.2
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• pp.177-183
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• 2015

Cross Site Scripting enables hackers to steal other user's information (such as cookie, session etc.) or to do abnormal functions automatically using vulnerability of web application. This attack patterns of Cross Site Scripting(XSS) can be divided into two types. One is Reflect XSS which can be executed in one request for HTTP and its reply, and the other is Stored XSS which attacks those many victim users whoever access to the page which accepted the payload transmitted. To correspond to these XSS attacks, some measures have been suggested. They are data validation for user input, output validation during HTML encoding procedures, and removal of possible risk injection point to prevent from trying to insert malicious code into web application. In this paper, the methods and procedures for these two types are explained and a penetration testing is done. With these suggestions, the attack by XSS could be understood and prepared by its countermeasures.

• Journal of Korean Society of Water and Wastewater
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• v.25 no.5
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• pp.681-689
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• 2011

Submerged membrane bio-reactor (SMBR) has several advantages such as high MLSS, long SRT, and low F/M ratio at wastewater treatment. So, this has widely applied over the world and many studies have been conducted. However, membrane fouling remains an inevitable problem. This study was investigated using bench-scale SMBR with three poeration modes. Raw waters were prepared by addition of starch, acetic and fibric acid to recovery water of zeolite. The efficiency of nitrification and COD were very stable as about 95% and 80%, respectively. And critical flux was 128.8L/$m^{2}$/hr. The result of biodegradability test was following values at the each mode : Ss+Xs/$C_{T}$=81.7%, 35.1% and 45.3%, $X_{I}+S_{I}/C_{T}=18.3%$, 64.9% and 54.7%. When particulate matters such as $X_{I}$ and $X_{S}$ in influent are increased, membrane fouling will take place more and more. A relative ratio of filtration resistance to the fouling occurred by the cake layer was increased when increased the portion of $X_{I}$ and polysaccharide. It was thought that the formation of cake layer was promoted due to bond between $X_{I}$ and vicid material s generated from the polysaccharide.

• Applied Biological Chemistry
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• v.21 no.3
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• pp.193-196
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• 1978

Wheat quality score index was proposed as a new criterion of wheat_quality for evaluation of the laboratory testing value such as milling rate (Xm), flour ash content (Xa), flour protein content (Xp) and sedimentation value (Xs). 1) Wheat quality score index was expressed as follows; Milling score index (MSI) $=2.3X_m-72.4X_a$ Protein score index (PSI) =$5.2X_p+0.9X_{psi}$ Composite quality score index (QSI) =$0.63X_{msi}+0.37X_{psi}$ 2) The samples with the more than 100 of MSI would be the good milliability, and the samples with more than 100 of PSI would be the good bread making properties, while that with less than 100 of PSI be good pastry type properties. Whereas most of the samples with higher value of QSI would be related to the good milliability and good bread making properties. 3) MSI, PSI and QSI were significantly correlated to the each related quality components.

• Korean Chemical Engineering Research
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• v.45 no.4
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• pp.410-413
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• 2007

The effect of internal donor(ID) in the heterogeneous Ziegler-Natta catalyst on the ethylene-1-butene copolymerization and the molecular structure of the resulting copolymer was investigated. $SiO_2$-supported $TiCl_4$ catalysts having ID/Ti molar ratio of 0.5 were prepared with ethyaluminium dichloride, magnesium alkyl, 2-ethyl-1-hexanol and $TiCl_4$. Three different IDs were employed such as ethylbenzoate(EB), diisobuylphthalate(DIBP) and dioctylphthalate(DOP). ID-added catalyst showed a larger fraction of Ti(+3) compared to that of no ID-added catalyst. The EB-added catalyst showed the highest activity in copolymerization. Xylene soluble value decreased by more than 50 % with ID-added catalysts compared to that of no ID-added catalyst. Crystaf analysis showed the chemical compositional distribution of PE copolymer was improved in the case of DIBP-added catalyst significantly. It could be explained that the presence of ID could make more even active sites and block the non-stereospecific active sites.

• The Research Journal of the Costume Culture
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• v.29 no.6
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• pp.849-864
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• 2021

This study analyzed product conditions in terms of "size system," "clothing construction depending on fit," "details," "colors," and "prices," with an emphasis on young contemporary brands for spring/summer 2021, in order to provide basic data for the development of small-sized women's jackets. Out of 96 domestic and foreign brands, the study analyzed 254 small-sized jacket products from 23 brands that produce size-XS jackets. First, when examining the sizes for women's jackets, we found that 8 out of the 23 brands offer a size-XXS option. After conducting tree analysis to analyze the factors affecting the production of size-XXS, the study found significant results in the areas of "distinction between domestic and foreign brands" and "product price." Second, after categorizing small-sized women's jackets into 3 categories-fit-slim, basic, and straight-the study analyzed clothing construction elements depending on fit. This seasons mainly feature straight-fit's hip-line length jacket, a 4-panel pattern, and a panel without a waist dart. Third, the study, through the analysis of the colors of small-sized women's jackets, found a higher frequency of colors in the order of black (23.0%), white (13.3%), and beige tones (10.1%), with additional colors such as sky blue, rose pink, and aquamarine in production, which exhibit the senses of the seasons. Price analysis revealed that small-sized jackets constituted a price range at the mid-to-low end, as in ₩50,000-100,000 (30.3%), ₩100,000-150,000 (19.3%), and ₩150,000-200,000 (11.8%).