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3D Printing-Based Ultrafast Mixing and Injecting Systems for Time-Resolved Serial Femtosecond Crystallography (시간 분해 직렬 펨토초 결정학을 위한 3차원 프린팅 기반의 초고속 믹싱 및 인젝팅 시스템)

  • Ji, Inseo;Kang, Jeon-Woong;Kim, Taeyung;Kang, Min Seo;Kwon, Sun Beom;Hong, Jiwoo
    • Korean Chemical Engineering Research
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    • v.60 no.2
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    • pp.300-307
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    • 2022
  • Time-resolved serial femtosecond crystallography (TR-SFX) is a powerful technique for determining temporal variations in the structural properties of biomacromolecules on ultra-short time scales without causing structure damage by employing femtosecond X-ray laser pulses generated by an X-ray free electron laser (XFEL). The mixing rate of reactants and biomolecule samples, as well as the hit rate between crystal samples and x-ray pulses, are critical factors determining TR-SFX performance, such as accurate image acquisition and efficient sample consumption. We here develop two distinct sample delivery systems that enable ultra-fast mixing and on-demand droplet injecting via pneumatic application with a square pulse signal. The first strategy relies on inertial mixing, which is caused by the high-speed collision and subsequent coalescence of droplets ejected through a double nozzle, while the second relies on on-demand pneumatic jetting embedded with a 3D-printed micromixer. First, the colliding behaviors of the droplets ejected through the double nozzle, as well as the inertial mixing within the coalesced droplets, are investigated experimentally and numerically. The mixing performance of the pneumatic jetting system with an integrated micromixer is then evaluated by using similar approaches. The sample delivery system devised in this work is very valuable for three-dimensional biomolecular structure analysis, which is critical for elucidating the mechanisms by which certain proteins cause disease, as well as searching for antibody drugs and new drug candidates.

A Study on the Possibility of Blockchain Technology Adoption in the Logistics Industry (물류산업 내 블록체인 기술 도입 가능성 연구)

  • Kye, Dong Min;Hur, Sung Ho
    • The Journal of The Korea Institute of Intelligent Transport Systems
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    • v.21 no.2
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    • pp.116-131
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    • 2022
  • With the recent progress of the 4th industrial revolution, the logistics industry is also making efforts to introduce smart logistics, and various attempts are being made to spread logistics informatization, which is the core of smart logistics. Among these, blockchain technology is considered as a technology that will contribute to the spread of logistics informatization and is being applied to various fields. Accordingly, in this study, to discuss the applicability of blockchain technology to the logistics industry, the characteristics of blockchain technology were defined, related cases were reviewed, and a survey was conducted on the possibility of application in the industry. Blockchain technology can be defined as having the characteristics of economic feasibility, speed, transparency in terms of work efficiency, and scalability, decentralization (decentralization), reliability (security) in terms of added value creation. It was confirmed that many are being introduced in the fields of distribution, finance, personal information, and public services. As a result of the survey on the logistics industry, it was confirmed that the level of informatization of the logistics industry had entered the stage of generating profits by using information, but the industry was passive in sharing and utilizing information due to concerns about information leakage. Nevertheless, the awareness and expectation of the need for informatization is high, and it is expected that the informatization of the logistics industry and realizing smart logistics based on it will advance one step further with the introduction of blockchain technology in the future.

Mobile Underground High-capacity 3D Spatial Information Tiling Transfer Protocol Development (모바일 지하 대용량 3D 공간정보 타일링 전송 프로토콜 개발)

  • Lee, Tae Hyung;Jo, Won Je;Kim, Hyun Woo
    • Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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    • v.39 no.6
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    • pp.491-496
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    • 2021
  • In line with the modern era in which the safety of underground facilities and the use of underground information are increasingly emphasized, the state is pushing for more precise and accurate underground spatial information to be secured and utilized. Therefore, we need to pay more attention to subsurface geospatial data. In the future, the Ministry of Land, Infrastructure and Transport will actively utilize the 15 types of Integrated Underground Geospatial Information Map(6 types of underground facilities, 6 types of underground structures, 3 types of ground) that the Ministry of Land, Infrastructure and Transport is building as three-dimensional underground spatial information, and contribute greatly to improving national safety and convenience in underground construction. expected to do However, when a site manager requests an Integrated Underground Geospatial Information Map with a mobile device, if the large-capacity integrated underground space map is not quickly transmitted over the wireless section and is not serviced, it causes inconvenience to the site manager and delays work. In this paper, the goal of this paper is to enable field managers to quickly receive a tiled Integrated Underground Geospatial Information Map with minimal information exchange. Therefore, the tiling system is configured according to the dataset for high-speed Mobile Integrated Underground Geospatial Information Map transmission. In addition, a transmission system for the Mobile Integrated Underground Geospatial Information Map is established, and a TCP/IP (Transmission Control Protocol/Internet Protocol)-based spatial information tiling transmission protocol dedicated to the on-site Integrated Underground Geospatial Information Map is developed.

NIRS Analysis of Liquid and Dry Ewe Milk

  • Nunez-Sanchez, Nieves;Varo, Garrido;Serradilla-Manrique, Juan M.;Ares-Cea, Jose L.
    • Proceedings of the Korean Society of Near Infrared Spectroscopy Conference
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    • 2001.06a
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    • pp.1251-1251
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    • 2001
  • The routine analysis of milk chemical components is of major importance both for the management of animals in dairy farms and for quality control in dairy industries. NIRS technology is an analytical technique which greatly simplifies this routine. One of the most critical aspects in NIRS analysis of milk is sample preparation and analysis modes which should be fast and straightforward. An important difficulty when obtaining NIR spectra of milk is the high water content (80 to 90%) of this product, since water absorbs most of the infrared radiation, and, therefore, limits the accuracy of calibrating for other constituents. To avoid this problem, the DESIR system was set up. Other ways of radiation-sample interaction adapted for liquids or semi-liquids exist, which are practically instantaneous and with limited or null necessity of sample preparation: Transmission and Folded Transmission or Transflectance. The objective of the present work is to compare the precision and accuracy of milk calibration equations in two analysis modes: Reflectance (dry milk) and Folded Transmission (liquid milk). A FOSS-NIR Systems 6500 I spectrophotometer (400-2500 nm) provided with a spinning module was used. Two NIR spectroscopic methods for milk analysis were compared: a) folded transmission: liquid milk samples in a 0.1 pathlength sample cell (ref. IH-0345) and b) reflectance: dried milk samples in glass fibre filters placed in a standard ring cell. A set of 101 milk samples was used to develop the calibration equations, for the two NIR analysis modes, to predict casein, protein, fat and dry matter contents, and 48 milk samples to predict Somatic Cell Count (SCC). The calibrations obtained for protein, fat and dry matter have an excellent quantitative prediction power, since they present $r^2$ values higher than 0.9. The $r^2$ values are slightly lower for casein and SCC (0.88 and 0.89 respectively), but they still are sufficiently high. The accuracy of casein, protein and SCC equations is not affected by the analysis modes, since their ETVC values are very similar in reflectance and folded transmission (0.19% vs 0.21%; 0.16% vs 0.19% and 55.57% vs 53.11% respectively), Lower SECV values were obtained for the prediction of fat and dry matter with the folded transmission equations (0.14% and 0.25% respectively) compared to the results with the reflectance ones (0.43% and 0.34% respectively). In terms of accuracy and speed of analytical response, NIRS analysis of liquid milk is recommended (folded transmission), since the drying procedure takes 24 hours. However, both analysis modes offer satisfactory results.

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Effect of Fertilizer Deep Placement on Rice and Soybean Yield Using Newly Developed Device for Deep Fertilization (신개발 심층시비장치를 이용한 심층시비가 벼와 콩 수량에 미치는 영향)

  • Sung-Chang Hong;Min-Wook Kim;Jin-Ho Kim
    • Korean Journal of Environmental Agriculture
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    • v.42 no.1
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    • pp.44-51
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    • 2023
  • Nitrogen fertilizer is an essential macronutrient that requires repeated input for crop cultivation. Excessive use of nitrogen fertilizers can adversely affect the environment by discharging NH3, NO, and N2O into the air and leaching into surrounding water systems through rainfall runoff. Therefore, it is necessary to develop a technology that reduces the amount of nitrogen fertilizer used without compromising crop yields. Fertilizer deep placement could be a technology employed to increase the efficiency of nitrogen fertilizer use. In this study, a deep fertilization device that can be coupled to a tractor and used to inject fertilizer into the soil was developed. The deep fertilization device consisted of a tractor attachment part, fertilizer amount control and supply part, and an underground fertilizer input part. The fertilization depth was designed to be adjustable from the soil surface down to a depth of 40 cm in the soil. This device injected fertilizer at a speed of 2,000 m2/hr to a depth of 25 to 30 cm through an underground fertilizer injection pipe while being attached to and towed by a 62-horsepower agricultural tractor. Furthermore, it had no difficulty in employing various fertilizers currently utilized in agricultural fields, and it operated well. It could also perform fertilization and plowing work, thereby further simplifying agricultural labor. In this study, a newly developed device was used to investigate the effects of deep fertilizer placement (FDP) compared to those with urea surface broadcasting, in terms of rice and soybean grain yields. FDP increased the number of rice grains, resulting in an average improvement of 9% in rice yields across three regions. It also increased the number of soybean pods, resulting in an average increase of 23% in soybean yields across the three regions. The results of this study suggest that the newly developed deep fertilization device can efficiently and rapidly inject fertilizer into the soil at depths of 25 to 30 cm. This fertilizer deep placement strategy will be an effective fertilizer application method used to increase rice and soybean yields, in addition to reducing nitrogen fertilizer use, under conventional rice and soybean cultivation conditions.

A Point of Production System for Semiconductor Wafer Dicing Process (반도체 웨이퍼 다이싱 공정을 위한 생산시점 정보관리시스템)

  • Kim, In-Ho
    • Journal of the Korea Society of Computer and Information
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    • v.14 no.10
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    • pp.55-61
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    • 2009
  • This paper describes a point of production(POP) system which collects and manages real-time shop floor machining information in a wafer dicing process. The system are composed of POP terminal, line controller and network. In the configuration of the system, LAN and RS485 network are used for connection with the upper management system and down stratum respectively. As a bridge between POP terminal and server, a line controller is used. The real-time information which is the base of production management are collected from information resources such as machine, product and worker. The collected information are used for the calculation of optimal cutting condition. The collection of the information includes cutting speed, spout of pure water, accumulated count of cut in process for blade and wafer defect. In order to manage machining information in wafer dicing process, production planning information is delivered to the shop floor, and production result information is collected from the shop floor, delivered to the server and used for managing production plan. From the result of the system application, production progress status, work and non-working hour analysis for each machine, and wafer defect analysis are available, and they are used for quality and productivity improvements in wafer dicing process. A case study is implemented to evaluate the performance of the system.

Study on the Applicability of CPT Based Soil Classification Chart (콘관입시험결과를 이용한 흙분류차트의 적용성에 관한 연구)

  • Kim, Chan-Hong;Im, Jong-Chul;Kim, Young-Sang
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.28 no.5C
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    • pp.293-301
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    • 2008
  • Soil profiling is one of the most important work among geotehnical engineering practice. Generally, soil profile is estimated from the observation of soil samples during subsurface exploration but such estimation also includes some experiencing aspects such as flushed water from the borehole, slime colour, boring speed and so on. In addition, since the capacity of hydraulic drill rig is significantly increased, thin layers might be easily missed. So, continuous soil profile is almost impossible over all depth to be bored from conventional subsurface exploration. While CPT or CPTu can serve continuous soil profile information over all depth generally in 5cm interval. Many charts or methods for soil profile from CPT result have been proposed during last several decades over the world. However they have not been verified in local ground condition in Korea. In this research, CPT results and soil classification results based on USCS were compiled from 17 sites over the Korea. Soil classification results by using 7 CPT soil classification charts were compared with those of USCS for the compiled database. Most proper CPT soil classification chart for Korean soil characteristics was evaluated and effective parameters for the soil classification from CPT were discussed. Finally interrelationship between CPT soil classification chart and USCS soil classification was evaluated.

The need for mechanization in todays canal building program in korea and overseas (수로의 기계화 시공의 필요성)

  • Ha, Gordon P.wkins
    • Magazine of the Korean Society of Agricultural Engineers
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    • v.21 no.2
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    • pp.21-27
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    • 1979
  • Canal construction is not the only area in which mechanization has advanced with great strides. All phases of the construction industry, including earthmoving, land clearing and levelling, road construction, and drainage and water control projects, have benefited from today's technological advancements. Lasers, an excellant example of advanced technology, have been refined for use as guidance systems for construction machinery, increasing accuracy and the speed of operation. The use of explosives by contractors is becoming more commonplace. One of the most valuable modern tools available today is the two-way radio. On today's sophisticated projects a single machine being down can frequently stop the progress of the entire project, delaying hundreds of men and machines from completing their assigned work for the day. The use of two-way radios in all the pickups and cars being used on a project facilitates communication so that emergency repairs can be effected immediately, and costly down time on any project can be reduced to a minimum. Not every construction project is suitable to mechanization. However, on the majority of projects mechanization has a great deal to offer the Korean contractor, and all contractors, in savings of time and money. Each and every project being considered by a contractor, should be closely examined for the most effective and efficient machinery application available. The International Commission on Irrigation and Drainage (ICID) has formed a committee on construction techniques being used in canal construction today. Two publications are now available describing the advances made in recent years. Standards for construction have been established for mechanized systems and this information is being distributed worldwide.

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Considerations for Implementing Online Art-Based Peer Supervision (온라인 미술기반 동료 슈퍼비전 실행에 대한 고려사항)

  • Yoon, Ra-Mi;Kim, Soo-In;Jung, HeeJae
    • The Journal of the Korea Contents Association
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    • v.22 no.5
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    • pp.404-415
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    • 2022
  • The purpose of this study is to propose considerations to help actual application based on the characteristics of the online art-based peer supervision execution process. Colleagues in the clinical art therapy doctoral program, including the researcher, attempted to repeatedly identify problems and apply improvements in the implementation process as research participants, and qualitatively analyzed the various data collected in the process. Looking at the characteristics of the analysis results, extensibility of materials and space was confirmed in terms of 'art-based' and initiative, convenience, and speed in terms of 'online'. The considerations identified through this are as follows. First, 'pre-structuring' should be based on clear boundaries and setting, prior consultation of the group, and self-directed preparation and attitude. Second, for the 'structural aspect of art', space and media to help immersion through creation, and stable implementation structure should be established. Third, in the 'technical aspect', it is necessary to apply a method that can deliver a work of art and a method that can communicate the creator's clear intention. Lastly, for the 'ethical aspect', it is necessary to use online software in accordance with the minimum security standards and to make efforts to repeatedly maintain confidentiality. This study is meaningful in that it suggested a practical method for maintaining the professional competence of art therapists and expanding networks among art therapists in various situations including pandemics.

Predicting Probability of Precipitation Using Artificial Neural Network and Mesoscale Numerical Weather Prediction (인공신경망과 중규모기상수치예보를 이용한 강수확률예측)

  • Kang, Boosik;Lee, Bongki
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.28 no.5B
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    • pp.485-493
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    • 2008
  • The Artificial Neural Network (ANN) model was suggested for predicting probability of precipitation (PoP) using RDAPS NWP model, observation at AWS and upper-air sounding station. The prediction work was implemented for flood season and the data period is the July, August of 2001 and June of 2002. Neural network input variables (predictors) were composed of geopotential height 500/750/1000 hPa, atmospheric thickness 500-1000 hPa, X & Y-component of wind at 500 hPa, X & Y-component of wind at 750 hPa, wind speed at surface, temperature at 500/750 hPa/surface, mean sea level pressure, 3-hr accumulated precipitation, occurrence of observed precipitation, precipitation accumulated in 6 & 12 hrs previous to RDAPS run, precipitation occurrence in 6 & 12 hrs previous to RDAPS run, relative humidity measured 0 & 12 hrs before RDAPS run, precipitable water measured 0 & 12 hrs before RDAPS run, precipitable water difference in 12 hrs previous to RDAPS run. The suggested ANN has a 3-layer perceptron (multi layer perceptron; MLP) and back-propagation learning algorithm. The result shows that there were 6.8% increase in Hit rate (H), especially 99.2% and 148.1% increase in Threat Score (TS) and Probability of Detection (POD). It illustrates that the suggested ANN model can be a useful tool for predicting rainfall event prediction. The Kuipers Skill Score (KSS) was increased 92.8%, which the ANN model improves the rainfall occurrence prediction over RDAPS.