• Asian Pacific Journal of Cancer Prevention
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• v.13 no.5
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• pp.1953-1956
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• 2012

Objective: The purpose of this study was to correlate the histological diagnosis made during intraoperative frozen section (FS) examination of hysterectomy samples with complex atypical endometrial hyperplasia (CAEH) diagnosed with definitive paraffin block histology. Methods: FS pathology results of 125 patients with a preoperative biopsy showing CAEH were compared retrospectively with paraffin block pathology findings. Results: Paraffin block results were consistent with FS in 78 of 125 patients (62.4%). The FS sensitivity and specificity of detecting cancer were 81.1% and 97.9%, with negative and positive predictive values of 76.7%, and 98.4%, respectively. Paraffin block results were reported as endometrial cancer in 77 of 125 (61.6%) patients. Final pathology was endometrial cancer in 45.3% patients diagnosed at our center and 76.9% for patients who had their diagnosis at other clinics (p=0.018). Paraffin block results were consistent with FS in 62.4% of all cases Consistence was 98.4% in patients who had endometrial cancer in FS. Conclusion: FS does not exclude the possibility of endometrial cancer in patients with the preoperative diagnosis of CAEH. In addition, sufficient endometrial sampling is important for an accurate diagnosis.

• Journal of The Korea Institute of Healthcare Architecture
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• v.8 no.2
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• pp.7-16
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• 2002

Modern society gradually change into diversification and specialization, the field of medical service also is specialized in these days. According to changes, A medical institution stress the need of women's min space of the concept "Well Women Clinic" Therefore, this study aims to propose improve way and architectural data after analysis the developing circumstances and problem on the architectural planning on the ward of women's hospital by case studies on the ward of women's hospital builded recently in korea.

• 대한생식의학회:학술대회논문집
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• 2006.06a
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• pp.174.1-174.1
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• 2006

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.8
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• pp.4877-4881
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• 2013

Background: The aim of the study was to assess the knowledge about HPV and HPV vaccines and attitudes towards vaccination among the females aged 9-24 years in Turkey. Materials and Methods: Self-administered questionnaires were filled out individually by the participants covering demographic information, knowledge about HPV infection and HPV vaccines, attitudes towards vaccination, and the perceptions of them about their parental attitudes about vaccination. Results: Of the 408 subjects participating in the study, 41.6% (n=170) had heard of HPV. Thirty-three percent (n=136) knew the causal relationship between HPV and cervical cancer. Only 27.9% (n=114) of them knew that HPV vaccines can prevent cervical cancer. Eleven percent (n=46) of the females participating in the study were willing to be vaccinated, and only 1.4% (n=6) were already vaccinated at the current time. The main reason listed among the participants who were not willing to be vaccinated was lack of information. Conclusions: Awareness and knowledge of Turkish female adolescents and young women about HPV, relation with cervical cancer and prevention of cervical cancer by Pap smear and vaccine are still limited. If the most important barrier to vaccination, which is reported as lack of information, were to be addressed, it would greatly impact the decision-making and vaccine acceptance.

• Journal of Genetic Medicine
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• v.14 no.1
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• pp.1-7
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• 2017

Purpose: The aim of this study was to assess the diagnostic efficacy of noninvasive prenatal screening for trisomy 18 by assessing the levels of unmethylated-maspin (U-maspin) and fetal nuchal translucency (NT) thickness during the first trimester of pregnancy. Materials and Methods: A nested case-control study was conducted using maternal plasma samples collected from 65 pregnant women carrying 11 fetuses with trisomy 18 and 54 normal fetuses. We compared the U-maspin levels, NT thicknesses, or a combination of both in the first trimester between the case and control groups. Results: U-maspin levels and NT thickness were significantly elevated in the first trimester in pregnant women carrying fetuses with trisomy 18 when compared to those carrying normal fetuses (27.2 vs. 6.6 copies/mL, P<0.001 for U-maspin; 5.9 vs. 2.0 mm, P<0.001 for NT). The sensitivities of the U-maspin levels and NT thickness in prenatal screening for fetal trisomy 18 were 90.9% and 90.9%, respectively, with a specificity of 98.1%. The combined U-maspin levels and NT thickness had a sensitivity of 100% in prenatal screening for fetal trisomy 18, with a specificity of 98.1%. Conclusion: A combination of U-maspin levels and NT thickness is highly efficacious for noninvasive prenatal screening of fetal trisomy 18 in the first trimester of pregnancy.

• 대한생식의학회:학술대회논문집
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• 2007.06a
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• pp.148-148
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• 2007

• Food Science and Biotechnology
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• v.18 no.1
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• pp.218-222
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• 2009

Ability of water extract from Prunella vulgaris Labiatae to stimulate immune system and inhibit tumor metastasis in mice was assessed. In experimental lung metastasis, prophylactic intravenous (i.v.) administration of water extract from P. vulgaris significantly inhibited lung metastasis in a dose-dependant manner. Peritoneal macrophages stimulated with P. vulgaris produced various cytokines such as tumor necrosis factor (TNF)-$\alpha$ and interlukin (IL)-12 as well as induced tumoricidal activity. In an assay for natural killer (NK) cell activity, i.v. administration of P. vulgaris significantly augmented NK cytotoxicity. The depletion of NK cells by injection of rabbit anti-asialo GM1 serum abolished the inhibitory effect of P. vulgaris on lung metastasis of colon26-M3.1 cells. These data demonstrate that P. vulgaris activate innate immune system to inhibit the growth of foreign materials including tumor cells in mice.

• The Korean Journal of Cytopathology
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• v.19 no.2
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• pp.164-167
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• 2008

Malakoplakia is an uncommon chronic granulomatous inflammation that usually involves the urinary and gastrointestinal tracts, but rarely affects the female genital tract. We experienced a case of malakoplakia in a cervicovaginal smear in a 54-year-old woman. Colposcopic examination showed a friable, easily bleeding tissue in the uterine cervix and the vaginal fornix. The cervicovaginal smear consisted of numerous isolated histiocytes, polymorphonuclear leukocytes, lymphocytes, and plasma cells. The histiocytes had an abundant, granular, and degenerated cytoplasm with inflammatory cell debris. Michaelis-Gutmann bodies were readily identified.

• 대한생식의학회:학술대회논문집
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• 2004.11a
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• pp.35-36
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• 2004

• Journal of Oriental Medical Thermology
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• v.9 no.1
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• pp.22-28
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• 2011

Purpose :To analyze body composition in postpartum women with cold-hypersensitivity, their edema index, skelectal muscle's weight and body fat were measured and analyzed with cold hypersensitive postpartum women compared with those of non-cold hypersensitivity. Methods : We studied 38 postpartum women visiting Gangnam Kyung-Hee Korean Hospital from 1 st October 2010 to 30th september 2011. they were subjected to Digital Infrared Thermal Imaging and those with thermal difference greater than $0.3^{\circ}C$ between anterior forearm and center of hand were diagnosed with cold hypersensitivity. Cold hypersensitivity group were consisted of 11 women, the other were consisted of 26 women. All of them were measured Edema index, skelectal muscle's weight and body fat by Inbody720(body composition scanner). We studied the difference of Body composition factor between two groups and relationship between cold-hypersensitivity, Edema index, skelectal muscle's weight and body fat by Independent Samples T-test and Spearman Correlation. Results : No significant differences were observed in edema index, skelectal muscle's weight and body fat between two groups. Conclusion : There was no significant relationship among the Cold-hypersensitivity and Body composition factor(Edema index, skelectal muscle's weight. body fat). But furthemore large scale study is required.