Effect of Prunella vulgaris Labiatae Extract on Innate Immune Cells and Anti-metastatic Effect in Mice
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Lee, Jun-Beom
(Shin Women's Hospital)
Kang, Tae-Bong (Department of Biological Chemistry, The Weizmann Institute of Science) Choi, Sang-Hoon (Department of Aquaculture Life Medicine, Kunsan National University) Lee, Ui-Young (Sanyacho-Nongwon) Kim, Ae-Jung (Department of Food and Nutrition, Hyejeon College) Jeong, Chang-Jin (Shin Women's Hospital) Lee, Hak-Cheon (Shin Women's Hospital) Cho, Yong-Sun (Shin Women's Hospital) Won, Jong-Gun (Shin Women's Hospital) Lim, Jong-Cheol (Shin Women's Hospital) Yoon, Taek-Joon (Department of Food and Nutrition, Yuhan College) |
1 | Wasser SP. Medicinal mushrooms as a source of antitumor and immunomodulating polysaccharides. Appl. Microbiol. Biot. 60:258-274 (2002) DOI PUBMED ScienceOn |
2 | Fisher M, Yang LX. Anticancer effects and mechanisms of polysaccharide-K (PSK): Implications of cancer immuno-therapy. Anticancer Res. 22: 1737-1754 (2002) PUBMED ScienceOn |
3 | An HJ, Um JY, Na HJ, Jeong S, Kim HM, Hong SH. Activation of inducible nitric oxide synthase by Kagamjuaguiem in peritoneal macrophages in mice. Indian J. Med. Res. 125: 740-746 (2007) |
4 | Azuma I, Seya T. Development of immunoadjuvants for immunotherapy of cancer. Int. Immunopharmaco. 1: 1249-1259 (2001) DOI ScienceOn |
5 |
Hunter CA, Chizzonite R, Remington JS. IL-1 |
6 | Fang X, Yu MM, Yuen WH, Zee SY, Chang RC. Immune modulatory effects of Prunella vulgaris L. on monocytes/macrophages. Int. J. Mol. Med. 16: 1109-1116 (2005) PUBMED ScienceOn |
7 | Markovic SN, Murasko DM. Role of natural killer and T-cells in interferon induced inhibition of spontaneous metastases of the B16F10L murine melanoma. Cancer Res. 51: 1124-1128 (1991) PUBMED ScienceOn |
8 | Chino A, Sakurai H, Choo MK, Koizumi K, Shimada Y, Terasawa K, Saiki I. Juzentaihoto, a Kampo medicine, enhances IL-12 production .by modulating toll-like receptor 4 signaling pathways in munne pentoneal exudate macrophages. Int. Immunopharmaco. 5:871-882 (2005) DOI ScienceOn |
9 | Kim SY, Kim SH, Shin HY, Lim JP, Chae BS, Park JS, Hong SG, Kim MS, Jo DG, Park WH, Shin TY. Effects of Prunella vulgaris on mast cell-mediated allergic reaction and inflammatory cytokine production. Exp. BioI. Med. 232: 921-926 (2007) |
10 | Schantz SP, Brown BW, Lira E, Taylor SL, Beddingfield N. Evidence for the role of natural immunity in the control of metastatic spread of head and neck cancer. Cancer Immunol. Immun. 25: 141-148 (1987) DOI ScienceOn |
11 | Pope BL, Sigindere J, Chourmouzis E, MacIntyre P, Goodman MG. 7-Allyl-8-oxoguanosine (loxoribine) inhibits the metastasis of B16 melanoma cells and has adjuvant activity in mice immunized with a B16 tumor vaccine. Cancer Immunol. Immun. 38: 83-91 (1994) DOI ScienceOn |
12 | Tanigawa K, Craig RA, Stoolman LM, Chang AE. Effects of tumor necrosis factor-alpha on the in vitro maturaton of tumor-reactive effector T cells. J. Immunother. 23: 528-535 (2000) DOI ScienceOn |
13 | Sung JY, Yoon TJ, Yu KW, Lee KH, Lee H. Enhancement of immunological activities in mice by oral administration of pectic polysaccharides from Eleutherococus senticosus. Food Sci. Biotechnol. 15: 117-121 (2006) 과학기술학회마을 |
14 | Colombo MP, Trinchieri G. Interleukin-12 in anti-tumor immunity and immunotherapy. Cytokine Growth F. R. 13: 155-168 (2002) DOI ScienceOn |
15 | Yoon TJ, Yoo YC, Kang TB, Baek YJ, Huh CS, Song SK, Lee KH, Azuma I, Kim JB. Prophylactic effect of Korean mistletoe (Viscum album coloratum) extract on tumor metastasis is mediated by enhancement of NK cell activity. Int. J. Immunopharmacol. 20: 163-172 (1998) DOI ScienceOn |
16 | Fang X, Chang RC, Yuen WH, Zee SY. Immune modulatory effects of Prunella vulgaris L. Int. J. Mol. Med. 15: 491-496 (2005) PUBMED ScienceOn |
17 | Kayagaki N, Yamaguchi N, Nakayama M, Takeda K, Akiba H, Tsutsui H, Okamura H, Nakanishi K, Okumura K, Yagita H. Expression and function of TNF-related apoptosis-inducing ligand on murine activated NK cells. J. Immunol. 163: 1906-1913 (1999) |
18 | Lee SJ, Saiki I, Hayakawa Y, Nunome S, Yamada H, Kim SH. Antimetastatic and immunomodulating properties of a new herbal prescription, Bojung-bangam-tang. Int. Immunopharmaco. 3: 147-157 (2003) DOI ScienceOn |
19 | Baxevanis CN, Voutsas IF, Tsitsilonis OE, Tsiatas ML, Gritzapis AD, Papamichail M. Compromised anti-tumor responses in tumor necrosis factor-alpha knockout mice. Eur. J. Immunol. 30: 1957-1966 (2000) DOI ScienceOn |
20 | Kim R, Emi M, Tanabe K. Cancer immunoediting from immune surveillance to immune escape. Immunology 121: 1-14 (2007) DOI ScienceOn |
21 | Saiki I, Saito S, Fujita C, Ishida H, Iida J, Murata J, Hasegawa A, Azuma I. Induction of tumoricidal macrophages and production of cytokines by synthetic muramyl dipeptide analogues. Vaccine 6:238-244 (1988) DOI ScienceOn |
22 | Villinger F. Cytokines as clinical adjuvants: How far are we? Expert Rev. Vaccines 2: 317-326 (2003) DOI ScienceOn |
23 | Lasek W, Feleszko W, Golab J, Stoklosa T, Marczak M, Dabrowska A, Malejczyk M, Jakobisiak M. Antitumor effects of the combination immunotherapy with interleukin-12 and tumor necrosis factor alpha in mice. Cancer Immunol. Immun. 45: 1000-1008 (1997) |
24 | Efferth T, Kaha S, Paulus K, Adams M, Rauh R, Boechzelt H, Hao X, Kaina B, Bauer R. Phytochemistry and pharmacogenomics of natural products derived from traditional Chinese medicine and Chinese materia medica with activity against tumor cells. Mol. Cancer Ther. 7: 152-162 (2008) DOI ScienceOn |
25 | Yoon n, Yoo YC, Lee SW, Shin KS, Choi WH, Hwang SH, Ha ES, Jo SK, Kim SH, Park WM. Anti-metastatic activity of Acanthopanax senticosus extract and its possible immunological mechanism of action. J. Ethnopharmacol. 93: 247-253 (2004) DOI PUBMED ScienceOn |
26 | Rubin H. The significance of biological heterogeneity. Cancer Metast. Rev. 1: 1-20 (1990) DOI |
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