• Journal of Korean Medical classics
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• v.23 no.1
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• pp.1-10
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• 2010

Wi Syndrome(痿證) mainly occurs from fluid damages[津液損傷] caused by heat in Gi(氣) phase of the Five viscera, while it sometimes come from the outside. Although the symptoms are presented in the limbs, the disorder roots in the Five viscera, most deeply located in the human body, Therefore, to approach the disorder, we must apply differentiation of the Five viscera in diagnosis. The Lungs, as the head of the Five viscera control the production and distribution of bodily fluids in the body. Functional disorder of the Lungs bring about Wi Syndrome regardless of it being in the Gi phase. Also, psychological depression leads to Wi Syndrome, In other words, depression and uneasiness easily results in the state of Gi blocking and fluid exhaustion in this modern society where there is less manual labor and excessive use of the brain. Besides Gi blockage, the top muscle[宗筋] theory is another important mechanism in the occurrence of Wi Syndrome. Moreover, the disorder is related to Yangmyeong(陽明), which is the sea of food, Chungmaek(衝脈) which is the sea of meridian, in addition to Immaek(任脈), Dokmeak (督脈) and Deameak(帶脈) which are all involved in Wi Syndrome. In conclusion, the Wi Syndrome happens when various factors involved lose balance and harmony with each other.

• Journal of Oriental Neuropsychiatry
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• v.18 no.2
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• pp.133-142
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• 2007

Wi syndrome is the syndrome that reveals muscle relaxation without contraction and muscle relaxation occurs in the low or upper limb, in severe case leads to death. We experienced a 80year-old woman who had a Wi syndrome, and treated by the way of reinforcing weakness of the spleen and stomach(脾胃虛弱). After being treated, the patient showed that symptoms (gait disturbance, ptosis, dysphonia) was improved. This result suggests that oriental medical treatment has good effect on Wi syndrome.

• Journal of Oriental Neuropsychiatry
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• v.22 no.2
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• pp.71-83
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• 2011

Delirium is an acute syndrome of disorientaion caused by dysfunction of brain and has many various symptoms. The characteristic symptoms of delirium are conscious disturbance with disorientation, dysarthria and emotional disturbance. We experienced 84-year-old man who had Wi syndrome(痿證) as well as delirium during the treatment of pneumonia, and whose condition was improved through Oriental medical treatment. The patient was diagnosed as Yangmyeong Disease(陽明病) that was caused by heat in the stomach and stool in the colon, and was treated with Daeseungki-tang (Dachengqi-tang, 大承氣湯). We were able to improve the delirium caused by high fever infection through Oriental medical treatment.

• Annals of Clinical Neurophysiology
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• v.10 no.1
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• pp.58-61
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• 2008

Sj$\ddot{o}$gren's syndrome (SS) is an autoimmune disease characterized by keratoconjunctivitis sicca and xerostomia. About thirty percent of patients with Sj$\ddot{o}$gren's syndrome experience nervous system involvement such as myelopaty, optic neuropathy, and peripheral neuropathy. The most common pattern of peripheral nerve involvement is axonal polyneuropathy. We present a case of demyelinating polyneuropathy in a patient with Sj$\ddot{o}$gren's syndrome, which had been proven by electrophysiology and pathology.

• Journal of Haehwa Medicine
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• v.17 no.1
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• pp.137-143
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• 2008

We have conclusions after the study of muscular system about large intestine channel of hand yangmyung muscle. 1. Judging from many studies of interrelation between Meridian muscle and muscle. it is considered that Meridian muscle theory has some similarities with modern anatomical muscular system. 2. There is a wide defference betwean myofacial pain syndrome and meridian muscle theory in that the former explains each muscle individually, while the latter classifies muscles systematically in the view of organism. 3. It is considered that large intestine channel of hand yangmyung muscle contains extensor digitorum muscle, extensor muscle of index finger, brachioradialis muscle, triceps brachii muscle, Rhomboid major muscle, trapezius muscle, sternocleidomastoid muscle and muscle levator labii. 4. The symptoms of large intestine channel of hand yangmyung muscle is similar to referred pain of modern Myofacial pain syndrome, and the medical treatment of "I-Tong-Wi-Su" is similar to that of Myofacial pain syndrome.

• Journal of fish pathology
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• v.32 no.1
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• pp.45-48
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• 2019

We developed and subsequently characterized mouse monoclonal antibodies (MAbs) against recombinant VP28 structural protein (rVP28) of white spot syndrome virus (WSSV). We established six hybridoma clones secreting MAbs against rVP28: 15A11, 20G6, 31H2, 34H6, 38D1 and 43A1. All six MAbs recognized the 25 kDa of protein in gill homogenates of WSSV-infected shrimp by western blot analysis, while no reactivity was observed in gill homogenates of normal shrimp. Moreover, high enzyme-linked immunosorbent assay (ELISA) optical density (OD) values (0.8-2.68) were observed in the hemolymphs from WSSV-infected shrimp, while low OD values (less than 0.24) were recorded in the hemolymphs from normal shrimp, by using these six MAbs produced in this study. These results suggest that these six MAbs are useful for the detection of WSSV.

• Journal of fish pathology
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• v.33 no.1
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• pp.71-75
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• 2020

A survey was conducted to investigate viral infections in 184 whiteleg shrimp (Litopenaeus vannamei) collected from nine farms and one wholesale fish vendor during 2018 and 2019. Gill and abdominal muscle of shrimp were tested for the presence of five viruses, viz. infectious hypodermal and haematopoietic necrosis virus, taura syndrome virus, infectious myonecrosis virus, yellow head virus genotype 1, and covert mortality nodavirus by reverse transcription-polymerase chain reaction (RT-PCR) and PCR. These viruses were not detected in any of 184 samples, screened under the study.

• Korean Journal of Ichthyology
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• v.29 no.1
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• pp.75-79
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• 2017

About 10% mortality occurred in cultured rainbow trout Oncorhynchus mykiss at a marine farm in Jeju in 2014. Diseased fish showed markedly abdominal distension and distended stomach. Although parasites, bacteria or viruses were not isolated from diseased fish, numerous Candida sp. were isolated from distended stomach. In experimental infection with Candida sp., mortality was not observed in most fish and clinical sign of distended stomach was not observed in the fish. These results suggest that Candida sp. may not be the etiologic agent of stomach distension syndrome. This is the first report of stomach distension syndrome in seawater farmed rainbow trout in Korea.

• Journal of fish pathology
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• v.35 no.2
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• pp.241-246
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• 2022

White spot syndrome virus (WSSV) is a prevalent and virulent pathogen affecting cultured whiteleg shrimp (Litopenaeus vannamei) in Korea. In this study, seven monoclonal antibodies (mAbs) (10A12, 16C3, 17G4, 21G5, 22C4, 23B6 and 24G6) were produced by using purified WSSV. The reactivity of these mAbs was analysed by Western blot (WB), indirect immunofluorescence (IIF), and lateral flow immunochromatographic assay (LFIA). WB analysis demonstrated that three mAbs (17G4, 22C4, and 23B6) reacted specifically to VP28 with an approximate molecular weight of 24 kDa, mAb 16C3 reacted with approximately 17 kDa. IIF analysis demonstrated specific fluorescence signals on gill tissues of WSSV-infected shrimp, with five mAbs (10A12, 16C3, 22C4, 23B6, and 24G6), pleopods from WSSV-infected shrimp were used for LFIA, where, two mAbs (21G5 and 22C4) exhibited positive reaction. In conclusion, it can be inferred that the mAbs usage and specificity depends on the nature of assay used for diagnosis.

• Journal of fish pathology
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• v.35 no.1
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• pp.129-133
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• 2022

The full genome sequence of a Korean white spot syndrome virus (WSSV, isolate: WSSV-GoC18) is presented here. We obtained a total of 12,320,554 reads with 291,172 bases, 170 gene, and 170 coding DNA sequence, which were assembled in 1 contig. Phylogenetic analysis revealed that the WSSV-GoC18 was closely related to Chinese isolate (WSSV-PC) and distinctly different with previously reported a Korean isolate (WSSV K-LV1). The complete genome sequence of WSSV isolates will be of great help in molecular epidemiological studies, contributing to molecular diagnosis and disease prevention in shrimp aquaculture.