• Journal of Nutrition and Health
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• v.28 no.9
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• pp.846-854
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• 1995

Taurine concentrations in blood and various tissues were measured in cats fed normal trurine diet(0.15% taurine) and trurine-free diet(0% taurine) for 5 weeks and 12 weeks, respectively. Cumulative body weight gain in young cats fed normal taurine diet and taurine-free diet for the initial 5 weeks were 463$\pm$43g and 383$\pm$53g respectively. Taurine concentration was one to two orders magnitude higher in most tissues than in plasma, among which the liver taurine-free diet for 12 weeks resulted in 98% reduction in plasma taurine concentration, 93% reduction in whole blood tarurine concentration, and 40~90% reduction in tissue taurine concentrations compared to the values for normal taurine diet group. Among the tissues tested, taurine depletion was most profound in heart and kidney, while liver and intestine were relatively resistant to taurine depletion. Whole blood taruined concentration appeared to be a better index for the body taurine status of cats as in more closely reflects the rate of taurine depletion in tissues. Taurine depletion in cats significantly increased the concentrations of essential and non-essential free amino acids in liver, while free amino acid concentrations in other tissues were not affected by taurine depletion.

• Journal of Chest Surgery
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• v.6 no.1
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• pp.41-46
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• 1973

This is a report on four cases of atelectasis which were implicated as one case of mucoid impaction and three cases of blood clots in main bronchus. The 1st case was found to be massive atelectasis on Lt. entire lung due to mucoid impaction with pulmonary tuberculosis. This case was performed the Lt. pneumonectomy. There are contain-ing impacted yellowish-gray jelly like thick materials on the Lt. whole bronchial trees and pathologic findings were consistent with tuberculosis including caseation necrosis and multinucleated giant cell on whole left lung thoroughly in microscopic findings. The 2nd and 3rd case [25 years old female and 30 years old female] were diagnosed as one sided entire lung ateletasis which were led by accumulation of old blood clots on bronchus following incomplete expectoration of sudden massive hemoptysis from pulmonary tuberculosis lesion. These two cases were recovered by removal of blood clots and bronchial irrigation under bronchoscopy. Follow up chest film revealed well aeration. The 4th case [45 years old] was taken the removal of old blood clots and tissue debris under the bronchoscopy as bronchial obstruction following massive hemoptysis. The cytologic findings revealed the class III in fresh sputum and class 1V in bronchial irrigation which may suggest of malignancy. However, we could not found the causative lesions suggestive malignancy by the bronchography and other diagnostic measurements.

• Journal of Acupuncture Research
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• v.20 no.1
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• pp.35-50
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• 2003

In order to study the effect of Bee venom(BV) on the subarachnoid hemorrhage animal model, the autologous whole blood was applied to the vicinity of the sprague dawley rat right femoral artery. Following periarterial application of autologous whole blood(PAB) and intraperitoneal injection of BV(1:5,000 nd 1:500), the vasomotor responses to BV(from 1:500,000 to 1:500) were identified and the histological changes, neovascularized blood vessel were observed. We have shown that alterations in vasomotor and histological findings are elicited following application of periarterial blood and i.p. injection of BV(1:5,000 and 1:500) induced heavy vasospasm and neovascularization on the subarachnoid hemorrhage like model form peripheral artery.

• Korean Journal of Optics and Photonics
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• v.24 no.6
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• pp.338-341
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• 2013

Prothrombin Time (PT) is used as a measure of blood coagulation time. An optical analysis of the signal generating mechanism is described here for the reflection-type arrangement. Thromboplastin added into serum or whole blood initiates the coagulation process. We added a sufficient amount of magnetic particles into the sample before adding thromboplastin and subjected the mixture to a rotating magnetic field. The laser light gets reflected in a periodically modulated fashion with respect to the magnetic field rotation. Analysis of this decaying modulation could produce a reasonable coagulation time. We also introduce a simulation model to explain the signal generating mechanism using LightTools.$^{TM}$

• The Journal of Korean Physical Therapy
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• v.17 no.3
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• pp.403-412
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• 2005

The purpose of this investigation is examining how treatment for foot reflex massage affect the changes in body temperature and blood composition. The cases of experiment are 10 male(n=2) and female(n=8) who don't have special clinical problems. This is the process of experiment. First, we photograph the anterior part and posterior of the upper, lower half of the body with an infrared imaging system. Second, among same parts, we compare the temperature of the whole body before treatment for foot reflex massage with the temperature after it. Then we draw blood from the body and observe a change: in numerical value of blood before and after treatment. Before and after treatment, we come to measure temperature of the whole body, the numerical value of WBC, RBC, platelet, HCT, Hb through analysis of blood, and the result of AST(GOT), ALT(GPT), ALP, GGT through analysis of serum enzyme activity of blood. There were no significant differences in blood composition. In terms of SPSS statistic program, when we explain each numerical value before and after foot massage, the abdominal, the buttocks, the femoral region universally take successful results about a change in body temperature(p<0.05).

• Journal of Biomedical Engineering Research
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• v.17 no.2
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• pp.227-234
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• 1996

This paper is the study of the diffusion constant in order to calculate the percent oxygenation and percent blood volume using reflectance light within biological tissue. The diffusion constant play major role in percent oxygenation and percent blood volume and varies with the biological material such as hemolyzed blood, whole blood, dermis and epidermis in vivo tissue. The diffusion constant can be modeled to consist of a contribution from bloodless tissue and blood present in tissue. The reflectance light for experimental are red light of 660nm, infrared light of 880nm, green light of 569nm. The correlation between the diffusion constant and biological tissue was analyzed by the intensity of reflectance light at different depth within human limb. The reflectance light was changed in response to physiological changes within biological tissue. The data for diffusion constant were obtained at different depth beneath the surface of the skin and will be utilized to amen the percent oxygenation and percent blood volume.

• Journal of Chest Surgery
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• v.35 no.6
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• pp.471-474
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• 2002

Transfusion associated graft-versus-host disease is a rare but fatal disease reported after open heart surgeries mainly in Asian people. It can be prevented by pretransfusion gamma irradiation of the fresh whole blood. In this presentation, we report a case of transfusion associated graft-versus-host disease following coronary artery bypass surgery in a 61 year-old male patient. Postoperatively the patient was transfused urgently with 2 units of fresh whole blood from his two sons. He was discharged on postoperative 10 day with only symptom of mild diarrhea. Two days after discharge, he was readmitted because of persistent diarrhea, systemic erythema and high fever. On laboratory examinations, he showed findings of failure in liver, kidney, gastrointestinal tract, and bone marrow. Hemodynamically he deteriorated acutely and died of multiple organ failure on 17th postoperative day. This has been our first experience since we started open heart program at our hospital and we changed our policy for the transfusion of the fresh whole blood after this event.

• 순환기질환의공학회:학술대회논문집
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• 2003.11a
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• pp.42-43
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• 2003

• IE interfaces
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• v.10 no.1
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• pp.119-134
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• 1997

The management of blood inventory is very important within the medical care system. The efficient management of blood supplies and demands for transfusions is of great economic and social importance to both hospitals and patients. For any blood type, there is a complex interaction among the optimal inventory level, daily demand level, daily supply level, transfusion to crossmatch ratio, crossmatch release period, issuing policy and the age of arriving units that determine the shortage and outdate rate. In this paper, we develop an efficient decision rule for blood inventory management in a hospital blood bank which can support efficient hospital blood inventory management using simulation. The primary use of the efficient decision rule will be to establish minimum cost function which consists of inventory levels, period in inventory, outdate and shortage rate for whole blood and various component inventories for a hospital blood bank or a transfusion service. If the administrator compute the mean daily demand for each blood type, the mean daily supply for each blood type, the length of the crossmatch release period and the average transfusion to crossmatch ratio, then it is possible to apply the efficient decision rule to compute the optimal inventory level, inventory period, outdate and shortage rate. This rule can also be used as a decision support system that allows the blood bank administrator to do sensitivity analysis related to controllable blood inventory parameters.

• Journal of the Korea Society for Simulation
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• v.5 no.1
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• pp.13-27
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• 1996

The management of blood inventory is very important within the medical care system. The efficient management of blood supplies and demands for transfusion is of great economic and social importance to both hospitals and patients. Fro any blood type, there is a complex interaction among the optimal inventory level, daily demand level , daily supply level, transfusion to crossmatch ratio, crossmatch release period, issuing policy and the age of arriving units that determine the shortage and outdate rate. In this paper, we develop an efficient decision rule for blood inventory management in a hospital blood bank which can support efficient hospital blood inventory management using simulation, The primary use of the efficient decision rule will be to establish minimum cost function which consists of inventory levels , period in inventory, outdate and shortage rate for whole blood and various component inventories for a hospital blood bank or a transfusion service, If the adminstrator compute the mean daily demand for each blood type, the mean daily supply for each blood type, the length of the crossmatch release period and the average transfusion to crossmatch ratio , then it is possible to apply the efficient decision rule to compute the optimal inventory level, inventory period , outdate and shortage rate. This rule can also be used as a decision support system that allows the blood bank adminstrator to do sensitivity analysis related to controlled blood inventory parameters.