Journal of Acupuncture Research

Korean Acupuncture & Moxibustion Medicine Society (대한침구의학회)
권호 표지

Effect of Bee Venom Therapy in a Rat Femoral Artery Model induced Vasospasm

봉독약침(蜂毒藥鍼)이 백서(白鼠) 대퇴동맥(大腿動脈)의 혈관연축(血管攣縮)에 미치는 영향(影響)

  • Kim, Jae-soo (Department of Acupuncture and Moxibustion, College of Oriental Medicine, Kyung-Hee University) ;
  • Kim, Hyung-hwan (Department of Herbology, College of Oriental Medicine, Kyung-Hee University) ;
  • Choi, Ho-young (Department of Herbology, College of Oriental Medicine, Kyung-Hee University) ;
  • Kim, Chang-hwan (Department of Acupuncture and Moxibustion, College of Oriental Medicine, Kyung-Hee University)
  • 김재수 (경희대학교 한의과대학 침구학교실) ;
  • 김형환 (경희대학교 한의과대학 본초학교실) ;
  • 최호영 (경희대학교 한의과대학 본초학교실) ;
  • 김창환 (경희대학교 한의과대학 침구학교실)
  • Received : 2002.12.03
  • Accepted : 2003.01.18
  • Published : 2003.02.20
Download PDF
⟨ Previous Next ⟩

Abstract

In order to study the effect of Bee venom(BV) on the subarachnoid hemorrhage animal model, the autologous whole blood was applied to the vicinity of the sprague dawley rat right femoral artery. Following periarterial application of autologous whole blood(PAB) and intraperitoneal injection of BV(1:5,000 nd 1:500), the vasomotor responses to BV(from 1:500,000 to 1:500) were identified and the histological changes, neovascularized blood vessel were observed. We have shown that alterations in vasomotor and histological findings are elicited following application of periarterial blood and i.p. injection of BV(1:5,000 and 1:500) induced heavy vasospasm and neovascularization on the subarachnoid hemorrhage like model form peripheral artery.

Keywords