• Title/Summary/Keyword: White Matter

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Apparent Digestibility Coefficients of Various Feed Ingredients for Olive Flounder, Paralichthys olivaceus (사료원료에 대한 넙치 Paralichthys olivaceus 소화율 평가)

  • Kim, Kyoung-Duck;Kim, Dong-Gyu;Kim, Shin-Kwon;Kim, Kang-Woong;Son, Maeng-Hyun;Lee, Sang-Min
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.43 no.4
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    • pp.325-330
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    • 2010
  • The apparent digestibility coefficients of dry matter, crude protein and energy in white fishmeal, herring meal, anchovy meal, salmon meal, sardine meal, mackerel meal, squid meal, soybean meal, corn gluten meal and wheat flour were determined for olive flounder. Digestibility coefficients were determined using a reference diet and test diets that contained 70% of the reference diet mixture and 30% test ingredients. All diets contained 0.5% chromic oxide as a digestibility indicator. The fish averaging 220 g were held in 500 L tanks at a density of 20 fish per tank. Feces were collected from three replicated groups of fish using a fecal collection column attached to a fish-rearing tank. The apparent dry matter, crude protein and energy digestibility coefficient values observed were in the ranges 29-79%, 59-95% and 45-91%, respectively, for various test ingredients. The apparent dry matter, crude protein and energy digestibility of white fishmeal, herring meal, anchovy meal, salmon meal, sardine meal, mackerel meal and squid meal were significantly higher than those of soybean meal, corn gluten meal and wheat flour.

Association between Characteristics of Brain Magnetic Resonance Imaging and Atypical Antipsychotics Use in Dementia Patients (치매 환자에서 뇌 자기공명영상의 특징과 비정형 항정신병 약제 사용여부의 상관 관계)

  • Choi, Jongtaek;Kim, Jiwon;Roh, Yangho;Rhu, Sukhwan;Woo, Sungil;Hahn, Sangwoo;Hwang, Jaeuk
    • Korean Journal of Biological Psychiatry
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    • v.20 no.3
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    • pp.97-103
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    • 2013
  • Objectives We aimed to identify the neuroimaging marker for prediction of the use of atypical antipsychotics (AAP) in dementia patients. Methods From April 2010 to March 2013, 31 patients who were diagnosed as dementia at the psychiatric department of Soonchunhyang University Hospital, completed the brain magnetic resonance imaging scan and cognitive test for dementia. Ten patients were treated with AAP for the improvement of behavioral and psychological symptoms of dementia (BPSD) and the other 21patients were not. Using T1 weighted and Fluid Attenuated Inversion Recovery (FLAIR) images of brain, areas of white matter (WM), gray matter (GM), cerebrospinal fluid (CSF) and white matter hyperintensities (WMH) have been segmented and measured. Multivariate logistic regression models were applied for assessment of association between AAP use and the GM/WM ratio, the WMH/whole brain (GM + WM + CSF) ratio. Results There was a significant association between AAP use and the GM/WM ratio (odds ratio, OR = 1.18, 95% confidence interval, CI 1.01-1.38, p = 0.037), while there was no association between AAP use and the WMH/whole brain ratio (OR = 0.82, 95% CI 0.27-2.48, p = 0.73). Conclusions The GM/WM ratio could be a biological marker for the prediction of AAP use and BPSD in patients with dementia. It was more likely to increase as dementia progress since atrophy of WM was more prominent than that of GM over aging.

A study on the food habits of Korean native goats fed with roughage sources (조사료원에 따른 한국 재래산양의 채식습성에 관한 연구)

  • Gang, Byung-Ho;Lee, In-Duk;Lee, Soo-Kee;Lee, Hyung-Suk
    • Korean Journal of Agricultural Science
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    • v.38 no.3
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    • pp.445-452
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    • 2011
  • The object of this experiment was to investigate the food habits of Korean native goats fed with various roughage sources. The experimental trials were conducted at Unbong Animal Genetic Resources Station in 2008. The experimental roughages include five sources and 25 species in all; grasses and legumes: 5 species (mixed grasses, orchardgrass, tall fescue, alfalfa, white clover), native grasses and weeds: 5 species (mixed native grasses, Miscanthus sinensis Anderss, Arundinella hirta (Thunb.) Tanaka, Barnyard grass, short awn, forage crops and straw: 5 species (barley + hairy vetch, wheat + hairy vetch, rye silage, barley silage, baled rice straw), browse and fallen leaves: 5 species (Mixed browse, Oriental white oak, Quercus serrta Thunb., Oriental cherry fallen leaves, Japanese chestnut fallen leaves), and imported hay and straw: 5 species(timothy hay, tall fescue straw, annual ryegrass straw, klinegrass hay, alfalfa hay). Ten Korean native goats were selected which had nearly the same body weight (average $24{\pm}2.8$ kg). The chemical composition and dry matter digestibility of each roughage source and species were significantly different at the sampling area, plant species, growth stages and cutting period (p<0.05). Among all the 25 species of roughages, the favorite intake species order by Korean native goat was observed like this: Quercus aliena, Querancas serrta Thunb and Mixed browse, which was a lower intake compared to other domestic herbivores. The Korean native goats ate more roughages which had low fibrous contents, but high dry matter digestibility. The Korean native goats ate more roughages which had low fibrous contents, but high dry matter digestibility. On the other hand, compared to each roughage source, total intake amount by Korean native goats was showed as browse and fallen leaves (33.1%) among trials roughage sources. Based on these results, the food habit of Korean native goats seems to be closer to the browser.

Acute disseminated encephalomyelitis in children: differential diagnosis from multiple sclerosis on the basis of clinical course

  • Lee, Yun-Jin
    • Clinical and Experimental Pediatrics
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    • v.54 no.6
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    • pp.234-240
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    • 2011
  • Acute disseminated encephalomyelitis (ADEM) is a demyelinating disease of the central nervous system (CNS) that typically presents as a monophasic disorder associated with multifocal neurologic symptoms and encephalopathy. ADEM is considered an autoimmune disorder that is triggered by an environmental stimulus in genetically susceptible individuals. The diagnosis of ADEM is based on clinical and radiological features. Most children with ADEM initially present with fever, meningeal signs, and acute encephalopathy. The level of consciousness ranges from lethargy to frank coma. Deep and subcortical white-matter lesions and gray-matter lesions such as thalami and basal ganglia on magnetic resonance imaging (MRI) are associated with ADEM. In a child who presents with signs of encephalitis, bacterial and viral meningitis or encephalitis must be ruled out. Sequential MRI is required to confirm the diagnosis of ADEM, as relapses with the appearance of new lesions on MRI may suggest either multiphasic ADEM or multiple sclerosis (MS). Pediatric MS, defined as onset of MS before the age of 16, is being increasingly recognized. MS is characterized by recurrent episodes of demyelination in the CNS separated in space and time. The McDonald criteria for diagnosis of MS include evidence from MRI and allow the clinician to make a diagnosis of clinically definite MS on the basis of the interval preceding the development of new white matter lesions, even in the absence of new clinical findings. The most important alternative diagnosis to MS is ADEM. At the initial presentation, the 2 disorders cannot be distinguished with certainty. Therefore, prolonged follow-up is needed to establish a diagnosis.

Large-Scale Environmental Effects on the Mass Assembly of Dark Matter Halos

  • Jung, Intae;Lee, Jaehyun;Yi, Sukyoung K.
    • The Bulletin of The Korean Astronomical Society
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    • v.38 no.1
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    • pp.32.2-32.2
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    • 2013
  • We examine large-scale environmental effects on the formation and the mass growth of dark matter halos. To facilitate this, we constructed dark matter halo merger trees from a cosmological N-body simulation, which enabled us to trace the merger information and the assembly history of individual halos. In fact, since the massive halos are more likely to be distributed in denser regions than in less dense regions (Mo & White, 1996), the large-scale environment dependence of the properties of halos can be partly originated from the halo mass effect. In order to avoid such contamination, caused by the mass dependence of halo properties, we carefully measured the local overdensity as the indicator of large-scale environment, which was calculated to be as independent of halo mass as possible. Small halos (${\sim}10^{11-12}M_{\odot}$), which usually host isolated single galaxies, show a notable difference on the formation time of galaxies depending on their large-scale environments, which reconfirms halo assembly bias (Gao & White, 2007). Furthermore, we investigate how this environmental effect on small halos is correlated with the mass assembly history of galaxies by using our semi-analytic model. We found that assembly bias in small halos does not have significant effects on the formation time or on the star formation history of galaxies residing in those halos except for the individual stellar mass of galaxies at z = 0. On average, isolated galaxies in high-density regions tend to be slightly more massive than those in low-density regions. Although the observational data from the current galaxy surveys is not yet sufficient for testing this prediction, future galaxy surveys will be able to explore these small galaxies more thoroughly.

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Usefulness of Brain Phantom Made by Fused Filament Fabrication Type 3D Printer (적층 제조형 방식의 3D 프린터로 제작한 뇌 팬텀의 유용성)

  • Lee, Yong-Ki;Ahn, Sung-Min
    • Journal of radiological science and technology
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    • v.43 no.6
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    • pp.453-460
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    • 2020
  • The price of the Brain phantom (Hoffman 3D brain phantom) used in nuclear medicine is quite expensive, it is difficult to be purchased by a medical institution or an educational institution. Therefore, the purpose of present research is to produce a low-price 3D brain phantom and evaluate its usefulness by using a 3D printer capable of producing 3D structures. The New 3D brain phantom consisted of 36 slices 0.7 mm thick and 58 slices 1.5 mm thick. A 0.7 mm thick slice was placed between 1. 5 mm thick slices to produce a composite slice. ROI was set at the gray matter and white matter scanned with CT to measure and compare the HU, in order to verify the similarity between PLA which was used as the material for the New 3D brain phantom and acrylic which was used as the material for Hoffman 3D brain phantom. As a result of measuring the volume of each Phantom, the error rate was 3.2% and there was no difference in the signal intensity in five areas. However, there was a significant difference in the average values of HU which was measured at the gray and white matter to verify the similarity between PLA and acrylic. By reproducing the previous Hoffman 3D brain phantom with a 100 times less cost, I hope this research could contribute to be used as the fundamental data in the areas of 3D printer, nuclear medicine and molecular imaging and to increasing the distribution rate of 3D brain phantom.

Productivity of Mixed Pasture as Affected by White Clover Varieties and Plant Height in Cutting Dates (화이트 클로바 품종 및 예취시 초장이 혼파 초지의 생산성에 미치는 영향)

  • Kim, M.C.;Ko, S.B.;Choi, D.Y.;Lee, J.E.;Kim, D.A.
    • Journal of The Korean Society of Grassland and Forage Science
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    • v.19 no.1
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    • pp.1-10
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    • 1999
  • To find out the way to be able to prolong the grazing years of mixed pasture under Cheju summer-hot weather, an experiment designed with split plot (main plot : 3 cutting-plant height such as 15cm, 30cm and 45cm and sub plot : 4 white clover varieties such as Regal, Tahora, Brown and SRVR) was carried out at Cheju Agricultural Experiment Station during the period from Sept. 1994 to Oct. 1996 Dry matter yield in 15cm plant height in cutting dates has shown significantly lower increase than those in 30 and 45cm(P<0.05). There was highiy significant increase in dry matter yield of Brown plot when compared with other varieties of white clover in 2nd year(P<0.01). There was no difference on botanical composition of mixed sward as affected by plant height in cuttings dates in 2nd year. The percentage of white clover tends to lower in white clover varieties Brown and SRVR when compared with Regal and Tahora. The rate of weed was not affected by plant height in cutting dates and white clover variety in mixed pasture at last cutting time of 2nd year. In 15cm plant height, concentration of ADE and NDF was the lowest one while P contents was the highest one(P<0.01). Potassium contents was the lowest one in 30cm plant cutting height(P<0.05), and nitrogen showed statistically interaction between plant cutting height and white clover variety(P<0.01). White clover variety was no effective on concentration of constituents in mixed pastures. In conclusion, white clover variety SRVR harvested at 15cm plant height is effective on nutrient value of pasture and balance of grass and white clover in botanical composition.

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Characteristics of White Charcoal Produced from the Charcoal Kiln for Thermotherapy (온열욕 겸용 숯가마에서 생산된 백탄의 특성)

  • Kwon, Gu Joong;Kim, Ah Ran;Lee, Hee Soo;Lee, Seung Hwan;Hidayat, Wahyu;Febrianto, Fauzi;Kim, Nam Hun
    • Journal of the Korean Wood Science and Technology
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    • v.46 no.5
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    • pp.527-540
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    • 2018
  • In this study, the characteristics of the white charcoal from charcoal kilns made for both charcoal production and thermotherapy and from the traditional charcoal kiln were compared and examined. A charcoal kiln for thermotherapy as a secondary purpose was made to minimize environmental problems such as fine dust and harmful gas generated from sealed charcoal kiln in consideration of comfort and safety. White Charcoal produced from the charcoal kiln for both charcoal production and thermotherapy had higher ash and volatile matter and lower fixed carbon than that from the traditional charcoal kiln. The density of the white charcoal produced from the charcoal kiln for both charcoal production and thermotherapy was slightly higher than that of the traditional one, but the equilibrium moisture content and pH were not significantly different. The calorific value, refinement degree, hardness and anatomical structure were not different between the two. It was concluded that the white charcoal produced from the advanced charcoal kiln for thermotherapy as a secondary purpose meets the quality certification standards of Korea Forest Research Institute.

Chemical Compositions and Microscopic observation of White Powder Formed in the Surface of Dried Persimmon (곶감표면에 생성되는 백색분말의 화학조성 및 현미경적 관찰)

  • Moon, Kwang-Deok;Lee, Nak-Hoon;Kim, Jong-Kuk;Kim, Jun-Han
    • Journal of the Korean Society of Food Culture
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    • v.11 no.1
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    • pp.1-5
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    • 1996
  • Chemical composition and microscopic observation of white powder developed in the surface of dried persimmon which produced in several region in Korea were studied. Sugar content in flesh of dried persimmon was $56{\sim}59%$ and composed of glucose and fructose. White powder developed in the surface of dried persimmon was composed of sugar 84.6%, moisture 12.5% and insoluble matter 2.7%, respectively. The major sugar of white powder was glucose with 83.3% and fructose was 16.7%. With scanning electron microscopic obsevation, white powder was seen the shape like a plate, flower, needle and horn, and it was similiar to the shape of recrystalized glucose after hydration. White powder in surface of dried persimmon was seemed that glucose and fructose in flesh were migrated with moisture to drying surface during drying process and glucose was crystalized in the surface of dried persimmon.

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A Case of Childhood Cerebral Form Adrenoleukodystrophy with Novel Mutation in the ABCD1 Gene (새로운 ABCD1 유전자의 돌연변이를 가지는 소아 대뇌형 부신백질이영양증 1례)

  • Shin, Young-Lim
    • Journal of The Korean Society of Inherited Metabolic disease
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    • v.12 no.1
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    • pp.49-53
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    • 2012
  • X-linked adrenoleukodystrophy (ALD) is a rare inherited metabolic disease which results in impaired peroxisomal ${\beta}$-oxidation and the accumulation of very long chain fatty acids (VLCFA) in the adrenal cortex, the myelin of the central nervous system, and the testes. X-linked ALD is caused by mutations in the ABCD1 gene encoding an ATP-binding cassette transporter superfamily located in the peroxisomal membrane. This disease is characterized by a variety of phenotypes. The classic childhood cerebral ALD is a rapidly progressive demyelinating condition affecting the cerebral white matter before the age of 10 years in boys. We report the case of a 8-year-old with childhood cerebral X-linked ALD who developed inattention, hyperactivity, motor incoordination and hemiparesis. We diagnosed ALD with elevated plasma very long chain fatty acid level and diffuse high signal intensity lesions in both parieto-occipital white matter and cerebellar white matter in brain MRI. We identified a novel c.983delT (p.Met329CysfsX7) mutation of the ABCD1 gene. There is no correlation between X-ALD phenotype and mutations in the ABCD1 gene. Further studies for searching additional non-genetic factor which determine the phenotypic variation will be needed.

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