• Title/Summary/Keyword: Weighted synthesis

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Large-scale Synthesis of Uniform-sized Nanoparticles for Multifunctional Medical Applications

  • Hyeon, Taeg-Hwan
    • Proceedings of the Korean Vacuum Society Conference
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    • 2011.02a
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    • pp.1-1
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    • 2011
  • We developed a new generalized synthetic procedure, called as "heat-up process," to produce uniform-sized nanocrystals of many transition metals and oxides without a size selection process. We were able to synthesize uniform magnetite nanocrystals as much as 1 kilogram-scale from the thermolysis of Fe-oleate complex. Clever combination of different nanoscale materials will lead to the development of multifunctional nano-biomedical platforms for simultaneous targeted delivery, fast diagnosis, and efficient therapy. In this presentation, I would like to present some of our group's recent results on the designed fabrication of multifunctional nanostructured materials based on uniform-sized magnetite nanoparticles and their medical applications. Uniform ultrasmall iron oxide nanoparticles of <3 nm were synthesized by thermal decomposition of iron-oleate complex in the presence of oleyl alcohol. These ultrasmall iron oxide nanoparticles exhibited good T1 contrast effect. In in vivo T1 weighted blood pool magnetic resonance imaging (MRI), iron oxide nanoparticles showed longer circulation time than commercial gadolinium complex, enabling high resolution imaging. We used 80 nm-sized ferrimagnetic iron oxide nanocrystals for T2 MRI contrast agent for tracking transplanted pancreatic islet cells and single-cell MR imaging. We reported on the fabrication of monodisperse magnetite nanoparticles immobilized with uniform pore-sized mesoporous silica spheres for simultaneous MRI, fluorescence imaging, and drug delivery. We synthesized hollow magnetite nanocapsules and used them for both the MRI contrast agent and magnetic guided drug delivery vehicle.

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VOICE SOURCE ESTIMATION USING SEQUENTIAL SVD AND EXTRACTION OF COMPOSITE SOURCE PARAMETERS USING EM ALGORITHM

  • Hong, Sung-Hoon;Choi, Hong-Sub;Ann, Sou-Guil
    • Proceedings of the Acoustical Society of Korea Conference
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    • 1994.06a
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    • pp.893-898
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    • 1994
  • In this paper, the influence of voice source estimation and modeling on speech synthesis and coding is examined and then their new estimation and modeling techniques are proposed and verified by computer simulation. It is known that the existing speech synthesizer produced the speech which is dull and inanimated. These problems are arised from the fact that existing estimation and modeling techniques can not give more accurate voice parameters. Therefore, in this paper we propose a new voice source estimation algorithm and modeling techniques which can not give more accurate voice parameters. Therefore, in this paper we propose a new voice source estimation algorithm and modeling techniques which can represent a variety of source characteristics. First, we divide speech samples in one pitch region into four parts having different characteristics. Second, the vocal-tract parameters and voice source waveforms are estimated in each regions differently using sequential SVD. Third, we propose composite source model as a new voice source model which is represented by weighted sum of pre-defined basis functions. And finally, the weights and time-shift parameters of the proposed composite source model are estimeted uning EM(estimate maximize) algorithm. Experimental results indicate that the proposed estimation and modeling methods can estimate more accurate voice source waveforms and represent various source characteristics.

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Galaxy Rotation Coherent with the Average Motion of Neighbors

  • Lee, Joon Hyeop;Pak, Mina;Lee, Hye-Ran;Song, Hyunmi
    • The Bulletin of The Korean Astronomical Society
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    • v.44 no.1
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    • pp.34.3-34.3
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    • 2019
  • We report our discovery of observational evidence for the coherence between galaxy rotation and the average motion of neighbors. Using the Calar Alto Legacy Integral Field Area (CALIFA) survey data analyzed with the Python CALIFA STARLIGHT Synthesis Organizer (PyCASSO) platform, and the NASA-Sloan Atlas (NSA) catalog, we estimate the angular momentum vectors of 445 CALIFA galaxies and build composite maps of their neighbor galaxies on the parameter space of velocity versus distance. The composite radial profiles of the luminosity-weighted mean velocity of neighbors show striking evidence for dynamical coherence between the rotational direction of the CALIFA galaxies and the average moving direction of their neighbor galaxies. The signal of such dynamical coherence is significant for the neighbors within 800 kpc distance from the CALIFA galaxies with a confidence level of $3.5{\sigma}$, when the angular momentum is measured at the outskirt ($Re<R{\leq}2Re$) of each CALIFA galaxy. We also find that faint or kinematically misaligned galaxies show stronger coherence with neighbor motions than bright or kinematically well-aligned galaxies do. Our results show that the rotation of a galaxy, particularly at its outskirt, may be significantly influenced by recent interactions with its neighbors.

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Crystallographic Evidence for the Reduction of CO in Partially Dehydrated Silver Zeolite A

  • Kim, Yang;Song, Seong-Hwan;Seff, Karl
    • Bulletin of the Korean Chemical Society
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    • v.10 no.3
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    • pp.230-234
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    • 1989
  • The crystal structure of $Ag^+$-exchanged zeolite A vacuum-dehydrated at $370^{\circ}C$ and then treated with carbon monoxide at $$23^{\circ}C$ has been determined by single crystal x-ray diffraction methods in the cubic space group Pm3m at $23^(1){\circ}C$ ; a = 12.116 (2)${\AA}$. The structure was refined to the final error indices $R_1\;=\;0.061\;and\;R_2$(weighted) = 0.068 using 349 independent reflections for which I > 3${\sigma}(I).\;3.6\;Ag_+-CO$ complexes, where -CO may represent -CHO or -$CH_2OH$, were found in each large cavity. By coordination to silver atoms followed by reaction with $Ag^{\circ}and\;H^+$ within the zeolite, carbon monoxide has been partially reduced. In about 28% of the sodalite units, a $Ag_6(Ag^+)_2$ cluster may be present. In about 37% of the sodalite units, three $Ag^+$ ions are found on threefold axes where they may be bridged by three water molecules. The remaining 35% of the sodalite units are empty of silver species. Two $Ag^+$ ions per unit cell are associated with 8-ring oxygens. The remaining ca $$3Ag^+$ ions per unit cell have been reduced during the synthesis and have migrated to form small silver crystallities on the surface of the zeolite single crystal.

Henry gas solubility optimization for control of a nuclear reactor: A case study

  • Mousakazemi, Seyed Mohammad Hossein
    • Nuclear Engineering and Technology
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    • v.54 no.3
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    • pp.940-947
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    • 2022
  • Meta-heuristic algorithms have found their place in optimization problems. Henry gas solubility optimization (HGSO) is one of the newest population-based algorithms. This algorithm is inspired by Henry's law of physics. To evaluate the performance of a new algorithm, it must be used in various problems. On the other hand, the optimization of the proportional-integral-derivative (PID) gains for load-following of a nuclear power plant (NPP) is a good challenge to assess the performance of HGSO. Accordingly, the power control of a pressurized water reactor (PWR) is targeted, based on the point kinetics model with six groups of delayed-neutron precursors. In any optimization problem based on meta-heuristic algorithms, an efficient objective function is required. Therefore, the integral of the time-weighted square error (ITSE) performance index is utilized as the objective (cost) function of HGSO, which is constrained by a stability criterion in steady-state operations. A Lyapunov approach guarantees this stability. The results show that this method provides superior results compared to an empirically tuned PID controller with the least error. It also achieves good accuracy compared to an established GA-tuned PID controller.

Spine Computed Tomography to Magnetic Resonance Image Synthesis Using Generative Adversarial Networks : A Preliminary Study

  • Lee, Jung Hwan;Han, In Ho;Kim, Dong Hwan;Yu, Seunghan;Lee, In Sook;Song, You Seon;Joo, Seongsu;Jin, Cheng-Bin;Kim, Hakil
    • Journal of Korean Neurosurgical Society
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    • v.63 no.3
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    • pp.386-396
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    • 2020
  • Objective : To generate synthetic spine magnetic resonance (MR) images from spine computed tomography (CT) using generative adversarial networks (GANs), as well as to determine the similarities between synthesized and real MR images. Methods : GANs were trained to transform spine CT image slices into spine magnetic resonance T2 weighted (MRT2) axial image slices by combining adversarial loss and voxel-wise loss. Experiments were performed using 280 pairs of lumbar spine CT scans and MRT2 images. The MRT2 images were then synthesized from 15 other spine CT scans. To evaluate whether the synthetic MR images were realistic, two radiologists, two spine surgeons, and two residents blindly classified the real and synthetic MRT2 images. Two experienced radiologists then evaluated the similarities between subdivisions of the real and synthetic MRT2 images. Quantitative analysis of the synthetic MRT2 images was performed using the mean absolute error (MAE) and peak signal-to-noise ratio (PSNR). Results : The mean overall similarity of the synthetic MRT2 images evaluated by radiologists was 80.2%. In the blind classification of the real MRT2 images, the failure rate ranged from 0% to 40%. The MAE value of each image ranged from 13.75 to 34.24 pixels (mean, 21.19 pixels), and the PSNR of each image ranged from 61.96 to 68.16 dB (mean, 64.92 dB). Conclusion : This was the first study to apply GANs to synthesize spine MR images from CT images. Despite the small dataset of 280 pairs, the synthetic MR images were relatively well implemented. Synthesis of medical images using GANs is a new paradigm of artificial intelligence application in medical imaging. We expect that synthesis of MR images from spine CT images using GANs will improve the diagnostic usefulness of CT. To better inform the clinical applications of this technique, further studies are needed involving a large dataset, a variety of pathologies, and other MR sequence of the lumbar spine.

Communication and data processing strategy for the electromagnetic wave precipitation gauge system (전파강수계 시스템의 통신 및 자료처리 전략 개발)

  • Lee, Jeong Deok;Kim, Minwook;Park, Yeon Gu
    • Journal of Satellite, Information and Communications
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    • v.12 no.4
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    • pp.62-66
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    • 2017
  • In this paper, we present the development of communication and data processing strategy for the electromagnetic wave precipitation gauge system. The electromagnetic wave precipitation gauge system is a small system for deriving area rainfall rates within 1 km radius through dual polarization radar observation at 24GHz band. It is necessary to take consider for measurement of accurate precipitation under limited computing resources originating from small systems and to minimize the use of network for the unattended operation and remote management. To overcome computational resource limitations, we adopted the fuzzy logic for quality control to eliminate non-precipitation echoes and developed the method by weighted synthesis of various rain rate fields using multiple radar QPE formulas. Also we have designed variable data packets rules to minimize the network traffic.

Pansharpening Method for KOMPSAT-2/3 High-Spatial Resolution Satellite Image (아리랑 2/3호 고해상도 위성영상에 적합한 융합기법)

  • Oh, Kwan-Young;Jung, Hyung-Sup;Jeong, Nam-Ki
    • Korean Journal of Remote Sensing
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    • v.31 no.2
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    • pp.161-170
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    • 2015
  • This paper presents an efficient image fusion method to be appropriate for the KOMPSAT-2 and 3 satellites. The proposed method is based on the well-established component substitution (CS) approach. The proposed method is divided into two parts: 1) The first step is to create a intensity image by the weighted-averaging operation of a multi-spectral (MS) image and 2) the second step is to produce an optimal high-frequency image using the statistical properties of the original MS and panchromatic (PAN) images. The performance of the proposed method is evaluated in both quantitative and visual analysis. Quantitative assessments are performed by using the relative global dimensional synthesis error (Spatial and Spectral ERGAS), the image quality index (Q4), and the spectral angle mapper index (SAM). The qualitative and quantitative assessment results show that the fusion performance of the proposed method is improved in both the spectral and spatial qualities when it is compared with previous CS-based fusion methods.

Dynamic risk assessment of water inrush in tunnelling and software development

  • Li, L.P.;Lei, T.;Li, S.C.;Xu, Z.H.;Xue, Y.G.;Shi, S.S.
    • Geomechanics and Engineering
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    • v.9 no.1
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    • pp.57-81
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    • 2015
  • Water inrush and mud outburst always restricts the tunnel constructions in mountain area, which becomes a major geological barrier against the development of underground engineering. In view of the complex disaster-causing mechanism and difficult quantitative predictions of water inrush and mud outburst, several theoretical methods are adopted to realize dynamic assessment of water inrush in the progressive process of tunnel construction. Concerning both the geological condition and construction situation, eleven risk factors are quantitatively described and an assessment system is developed to evaluate the water inrush risk. In the static assessment, the weights of eight risk factors about the geological condition are determined using Analytic Hierarchy Process (AHP). Each factor is scored by experts and the synthesis scores are weighted. The risk level is ultimately determined based on the scoring outcome which is derived from the sum of products of weights and comprehensive scores. In the secondary assessment, the eight risk factors in static assessment and three factors about construction situation are quantitatively analyzed using fuzzy evaluation method. Subordinate levels and weight of factors are prepared and then used to calculate the comprehensive subordinate degree and risk level. In the dynamic assessment, the classical field of the eleven risk factors is normalized by using the extension evaluation method. From the input of the matter-element, weights of risk factors are determined and correlation analysis is carried out to determine the risk level. This system has been applied to the dynamic assessment of water inrush during construction of the Yuanliangshan tunnel of Yuhuai Railway. The assessment results are consistent with the actual excavation, which verifies the rationality and feasibility of the software. The developed system is believed capable to be back-up and applied for risk assessment of water inrush in the underground engineering construction.

Effectiveness of low-level laser therapy on recovery from neurosensory disturbance after sagittal split ramus osteotomy: a systematic review and meta-analysis

  • Firoozi, Parsa;Keyhan, Seied Omid;Kim, Seong-Gon;Fallahi, Hamid Reza
    • Maxillofacial Plastic and Reconstructive Surgery
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    • v.42
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    • pp.41.1-41.11
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    • 2020
  • Background: Orthognathic surgery such as bilateral sagittal split ramus osteotomy (BSSRO) for the treatment of mandibular deformities is one of the most common procedures in maxillofacial operations that may lead to neurosensory disturbance. In this study, we aimed to evaluate the effectiveness of low-level laser therapy (LLLT) on augmenting recovery of neurosensory disturbance of inferior alveolar nerve (IAN) in patients who underwent BSSRO surgery. Methods: A comprehensive literature search was conducted by two independent authors in PubMed, Cochrane Central Register of Controlled Trials (CENTRAL), Scopus, Embase, and Google Scholar electronic databases. Besides, a manual search of all textbooks and relevant articles were conducted. Searches took place in August 2020 and were limited to published and peer-reviewed articles from 2000 to 2020. All analysis was performed using the comprehensive meta-analysis (CMA) and the STATA MP (version:16) software. The weighted mean difference (WMD) using the inverse variance method and the standard mean difference (SMD) was considered for continuous variables. Results: Seventy-four papers were retrieved after removing duplicate studies and finally, eight studies were assessed for qualitative synthesis and five for meta-analysis. Totally, 94 patients were included in the meta-analysis. Based on the meta-analysis, it was shown that LLLT was not effective in a short interval (0 to 48 h) after surgery, but in a period of more than 1 month after surgery, the positive results of treatment can be observed strikingly. Also, LLLT side/group showed no significant difference in some aspects of neurosensory recovery such as thermal sensation compared to the placebo side/group. Conclusions: The meta-analysis of randomized controlled trials revealed that LLLT generally improves IAN sensory disturbance caused by BSSRO. Further high-quality clinical trials with longer follow-up periods and larger sample sizes are recommended.