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Epr Study of the 10-Tungsto-2-vanado(Ⅳ, Ⅴ)phosphate Anion, [PV(Ⅳ)VW$_{10}O_{40}]^{6-}$

  • Lee, Chul-Wee;So, Hyun-Soo;Lee, Kyu-Ryong
    • Bulletin of the Korean Chemical Society
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    • v.7 no.1
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    • pp.39-41
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    • 1986
  • The polycrystalline epr spectrum of ${\alpha}-1,\;2-[PV(IV)VW_{10}O_{40}]^{6-}$ doped into host crystals and its solution spectrum are reported. The solution spectrum consists of fifteen lines, indicating that the unpaired electron is hopping fast between the two vanadium atoms. The polycrystalline spectrum, which consists of three sets of fifteen lines, was analyzed as a spectrum of an I = 7 system and the epr parameters were determined. The spectrum cannot be interpreted by assuming that each line appears at the average magnetic field of two hyperfine lines expected for two uncoupled vanadium atoms.

Prediction of hub genes of Alzheimer's disease using a protein interaction network and functional enrichment analysis

  • Wee, Jia Jin;Kumar, Suresh
    • Genomics & Informatics
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    • v.18 no.4
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    • pp.39.1-39.8
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    • 2020
  • Alzheimer's disease (AD) is a chronic, progressive brain disorder that slowly destroys affected individuals' memory and reasoning faculties, and consequently, their ability to perform the simplest tasks. This study investigated the hub genes of AD. Proteins interact with other proteins and non-protein molecules, and these interactions play an important role in understanding protein function. Computational methods are useful for understanding biological problems, in particular, network analyses of protein-protein interactions. Through a protein network analysis, we identified the following top 10 hub genes associated with AD: PTGER3, C3AR1, NPY, ADCY2, CXCL12, CCR5, MTNR1A, CNR2, GRM2, and CXCL8. Through gene enrichment, it was identified that most gene functions could be classified as integral to the plasma membrane, G-protein coupled receptor activity, and cell communication under gene ontology, as well as involvement in signal transduction pathways. Based on the convergent functional genomics ranking, the prioritized genes were NPY, CXCL12, CCR5, and CNR2.

Analysis of the Gene Expression by Laser Capture Microdissection(II) : Differential Gene Expression between Primordial and Primary Follicles (Laser Capture Microdissection을 이용한 유전자 발현 연구(II) : 원시난포와 1차난포 유전자 발현의 차이에 대한 분석)

  • 박창은;고정재;이숙환;차광렬;김격진;이경아
    • Development and Reproduction
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    • v.6 no.2
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    • pp.89-96
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    • 2002
  • The present study was conducted to elucidate genes involved in the primordial-primary follicular transition. By using suppression subtractive hybridization, day1- and day5-subtracted cDNA libraries were obtained with the forward and reverse subtraction method, respectively. In toto, 357 clones were sequenced and analyzed by BLAST and RIKEN program. Sequences of 330 clones significantly matched database entries while 27 clones were novel. Forty-two and 47 genes with known functions were different between day1 and day5 ovaries. Four genes, GDF8, lats2, septin2, and wee1, from the day1 subtracted cDNA library, and 6 genes, HSP84, laminin2, MATER, MTi7, PTP, and wrn, from day5-subtracted cDNA library were chosen, and their differential expression was evaluated using RNAs from whole ovaries as well as captured primordial and primary follicles by laser captured microdissection. Results from the present study would provide insight for the future study on the mechanisms involved in primordial-primary follicle transition in the mouse in addition to the human ovary.

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Effects of Hafnium, Boron and Zirconium on the Ductility of Ni$_3$(Al, Fe) Intermetallic Compounds

  • Lim, S.H.;No, J.Y.;No, K.S.;Wee, D.M.
    • Korean Journal of Materials Research
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    • v.2 no.4
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    • pp.306-310
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    • 1992
  • Effects of hafnium, boron and zirconium on the ductility of Ni$_3$(Al, Fe) intermetallic compounds were studied using tensile test and SIMS analysis. Ni$_3$(Al, Fe) alloy with 0.1 at.% Hf, 0.05 at.% B and 0.1 at.% Zr additions showed maximum elongations of about 30% at 300K, 10% at 300K and 14% at 473K, respectively. The fracture mode of the alloy without the additive was the mixture of intergranular and transgranular fractures, but the addition of Hf, Zr or B changed the fracture mode to transgranular only. SIMS analysis showed that the beneficial effects of Hf, Zr or B segregation on the grain boundary strength are consistent with the grain boundary cohesion theory.

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Near-end Cross-talk Analysis of Unshielded Twisted Pair Cable using the Transmission Line Model (전송선로 모델을 이용한 UTP 케이블의 NEXT 해석)

  • Lee, Won-Hui;Park, Wee-Sang
    • The Journal of the Institute of Internet, Broadcasting and Communication
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    • v.9 no.2
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    • pp.59-63
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    • 2009
  • The UTP cable has been widely used, recently it is being developed for use in the UHF frequency band. One important characteristic of the UTP cable is NEXT. This research is to develop a pitch selection technique for an UTP cable which leads to a satisfactory NEXT. The transmission line model involving mutual inductances and capacitances between line pairs is used, and the simulation was carried out for frequencies from 1 MHz to 600 MHz. With respect to the worst margin of the NEXT for a Cat. 6 cable the simulation and measurement results show a good agreement.

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Effectiveness of Oriental Medical Therapy and Bongchuna on Anterior Cruciate Ligament Rupture of Knee, Two Case Reports (슬관절의 전방십자인대파열에 대한 한방치료와 봉추나의 치료효과 증례 2)

  • Oh, Won-Kyo;Kwon, Young-Dal;Song, Yung-Sun
    • Journal of Korean Medicine Rehabilitation
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    • v.20 no.4
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    • pp.241-254
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    • 2010
  • Anterior cruciate ligament tear is a common disease of knee injury. We report 1 case of anterior cruciate ligament complete tear diagnosed by MRI(magnetic resonance imaging) imaging and 1 case after reconstruction. Outcomes were measured by visual analogue scale(VAS) and Lysholm knee scoring scale. We applied acupuncture treatment, bee venom injection, bongchuna and prescribed herbal medication. Patients who treated by oriental medical treatments had a significant effect on the pain decrease and range of motion and knee function. Oriental medical treatments are very useful on pain reduction and prevention of muscle contraction, leading to satisfied rehabilitation, as wee as diminishing recurrence after operation.

A Comparision of Mghr Prescription to Doses at Ponts A and B in Intracavitary Radiotherapy of Cervix Cancer (자궁경구암(子宮頸口癌) 강내조사치료시(腔內照射治療時) A점(點) B점(點) 선량계산방법(線量計算方法)과 mghr 단위(單位) 방법(方法)의 비교(比較))

  • Park, Charn-Il;Ha, Sung-Whan;Kang, Wee-Saing
    • Journal of Radiation Protection and Research
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    • v.6 no.1
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    • pp.31-33
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    • 1981
  • The 42 patients with carcinoma of the cervix, performed intracavitary radiotherapy, were analysed the doses at points A and B comparing to the mghr prescription. The doses at points A and B were calculated by PC-12 computer planning system. Correlation coefficienty between doses at points A and B and the mghr prescription are 0.82 (p<0.001) and 0.90 (p<0.001) respectively. The slope of the point A line is 0.70 and the slope of the point B is 0.21. Therefore, the dose at point A is approximately 3/4 the mghr prescription and the dose at point B is approximately 1/4 the mghr precription.

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Collaboration Inventory System with Limited Resources and Weibull Distribution Deterioration

  • Wee, Hui-Ming;Law, Sh-Tyan;Yu, Jonas
    • Industrial Engineering and Management Systems
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    • v.6 no.1
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    • pp.1-10
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    • 2007
  • The objective of this study is to develop an optimal joint cost from the perspectives of both the manufacturer and the retailer. The integrated production-inventory model with Weibull distribution deteriorating items is assumed to have a constant demand rate. A limited retailer storage space and multiple delivery per order are considered in this model. A numerical example including the sensitivity analysis is given to validate the results of the production-inventory model.

Incidence and Morphology of Buxtonella sulcata from Cattle in Chonnam Area (전남지방(全南地方) 소의 Buxtonella sulcata 감염실태(感染實態)와 충(蟲)의 형태(形態))

  • Wee, Seong-hwan;Park, Young-jun;Lee, Chung-gil
    • Korean Journal of Veterinary Research
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    • v.26 no.1
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    • pp.157-161
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    • 1986
  • Samples of feces from 1,080 cattle in Chonnam area were examined for Buxtonella sulcata, Of these, 231 cattle (21.4%) were found to be infected with the ciliate. The incidence was higher in the dairy cattle than in the beef cattle. The cysts of the ciliate are almost spherical or sub-spherical and the mean length of $79.58{\pm}11.76{\mu}m$ corresponds quite closely with the mean width of $77.29{\pm}11.41{\mu}m$. The trophozoite is characterized by the position of the cytostome near the open cytopyge and by the curved groove running down from cytostome to the end of the body. Macronuclei of the cyst and trophozoite were only stained green by MFS solution.

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