• Animal cells and systems
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• v.16 no.1
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• pp.11-19
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• 2012

A major concern regarding the collection and storage of biodiversity information is the inefficiency of conventional taxonomic approaches in dealing with a large number of species. This inefficiency has increased the demand for automated, rapid, and reliable molecular identification systems and large-scale biological databases. DNA-based taxonomic approaches are now arguably a necessity in biodiversity studies. In particular, DNA barcoding using short DNA sequences provides an effective molecular tool for species identification. We constructed a large-scale database system that holds a collection of 5531 barcode sequences from 2429 Korean species. The Korea Barcode of Life database (KBOL, http://koreabarcode.org) is a web-based database system that is used for compiling a high volume of DNA barcode data and identifying unknown biological specimens. With the KBOL system, users can not only link DNA barcodes and biological information but can also undertake conservation activities, including environmental management, monitoring, and detecting significant organisms.

• Journal of KIISE:Databases
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• v.37 no.5
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• pp.258-266
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• 2010

In this paper, we introduce a novel method to predict next update of blogs. The number of RSS feeds registered on meta-blogs is on the order of several million. Checking for updates is very time consuming and imposes a heavy burden on network resources. Since blog search engine has limited resources, there is a fix number of blogs that it can visit on a day. Nevertheless we need to maximize chances of getting new data, and the proposed method which predicts update probability on blogs could bring better chances for it. Also this work is important to avoid distributed denial-of-service attack for the owners of blogs. Furthermore, for the internet as whole this work is important, too, because our approach could minimize traffic. In this study, we assumed that there is a specific pattern to when a blogger is actively posting, in terms of days of the week and, more specifically, hours of the day. We analyzed 15,119 blogs to determine a blogger's posting preference. This paper proposes a method to predict the update probability based on a blogger's posting history and preferred days of the week. We applied proposed method to 12,115 blogs to check the precision of our predictions. The evaluation shows that the model has a precision of 0.5 for over 93.06% of the blogs examined.

• Journal of Nuclear Fuel Cycle and Waste Technology(JNFCWT)
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• v.4 no.1
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• pp.65-75
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• 2006

Transparency on the Total System Performance Assessment (TSPA) is the key issue to enhance the public acceptance for a radioactive repository. To approve it, all performances on TSPA through Quality Assurance is necessary. The integrated Cyber R&D Platform is developed by KAERI using the T2R3 principles applicable for five major steps : planning, research work, documentation, and internal & external audits in R&D's. The proposed system is implemented in the web-based system so that all participants in TSPA are able to access the system. It is composed of three sub-systems; FEAS (FEp to Assessment through Scenario development) showing systematic approach from the FEPs to Assessment methods flow chart, PAID (Performance Assessment Input Databases) being designed to easily search and review field data for TSPA and QA system containing the administrative system for QA on five key steps in R&D's in addition to approval and disapproval processes, corrective actions, and permanent record keeping. All information being recorded in QA system through T2R3 principles is integrated into Cyber R&D Platform so that every data in the system can be checked whenever necessary. Throughout the next phase R&D, Cyber R&D Platform will be connected with the assessment tool for TSPA so that it will be expected to search the whole information in one unified system.

• Journal of KIISE:Databases
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• v.34 no.6
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• pp.528-545
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• 2007

Recently ontology has been an attractive technology along with the business strategy of providing a plenty of more intelligent services. The essential problem in application domains using ontology is that all members, agents, and application programs in the domains must share the same ontology concepts. However, a variety of mobile devices, sensing devices, and network components manufactured by various companies, a variety of common carriers, and a variety of contents providers make multiple heterogeneous ontologies more likely to coexist. We can see many past researches fallen into resolving this semantic interoperability. Such methods can be broadly classified into by-mapping, by-merging, and by-translation. In this research, we focus on by-translation among them which uses a translation rule directly made between two heterogeneous ontology data like OntoMorph. However, the manual composition of the direct translation rule is not convenient by itself and if there are N ontologies, the direct method has the rule composition complexity of $O(N^2)$ in the worst case. Therefore, in this paper we introduce the cascade composition of translation rules based on web openness in order to improve the complexity. The research result made us recognize some important factors in an ontology translation system, that is speediness of translation, and conveniency of translation rule composition, and some experiments and comparing analysis with existing methods showed that our cascade method has more conveniency with insuring the speediness and the correctness.

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.1
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• pp.399-403
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• 2013

Background: Several studies have reported the role of the miR-146a rs2910164 G > C polymorphism as a susceptibility factor for several digestive cancers. However, the results have been controversial. Therefore, we conducted the present meta-analysis to obtain the most reliable estimate of the association. Methods: PubMed, Embase and Web of Science databases were searched. Crude odds ratios (ORs) with 95% confidence intervals (CIs) were extracted and pooled to assess the strength of the association between miR-146a rs2910164 G > C polymorphism and digestive cancer risk. A total of four eligible studies including 3,447 cases and 5,041 controls based on the search criteria were included. Results: We observed that miR-146a rs2910164 G > C polymorphism was not significantly correlated with digestive cancer risks when all studies were pooled into the meta-analysis. While we found that miR-146a rs2910164 polymorphism was not associated with gastric cancer, it was significantly linked with hepatocellular cancer risk (the homozygote codominant model: OR = 1.40, 95% CI = 1.04-1.87). In the stratified analysis by ethnicity, significant associations were observed in Chinese population for the allele contrast model (OR = 1.25; 95% CI = 1.12-1.38), for the homozygote codominant model (OR = 1.62; 95% CI = 1.28-2.04), and for the recessive model (OR = 1.38; 95% CI = 1.16-1.64). However, studies with Asian groups presented no significant association for all genetic models. Conclusions: This meta-analysis suggests that the miR-146a rs2910164 G > C polymorphism is a low-penetrant risk factor for digestive cancers in Chinese.

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.3
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• pp.1925-1929
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• 2013

Background: As a negative regulator of P53, MDM2 plays an important role in carcinogenesis; a polymorphism in its promoter region. SNP309 T>G, is known to increase the expression of MDM2, thus being considered related to higher susceptibility to neoplasia. However, no agreement has been achieved regarding its effects on gastric cancer. Methods: The present systematic meta-analysis was performed based on comprehensive literature search from Pubmed, Web of science and CBM databases. Results: It was suggested from 6 independent studies that the GG genotype is associated with a significantly increased risk of gastric cancer (Recessive: OR = 1.43, 95% CI = 1.08-1.91, P = 0.013), and subgroup analysis also confirmed the relationship (English publications-recessive model: OR = 1.45, 95% CI = 1.10-1.91, P = 0.009; Studies in China-recessive model: OR = 1.58, 95% CI = 1.08-2.30, P = 0.017). No publication bias was detected. Conclusion: The meta-analysis indicated a significant inverse association between GG genotype carriage and elevated risk of gastric cancer. However, more studies and detailed information are needed to fully address the topic.

• Asian Pacific Journal of Cancer Prevention
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• v.13 no.8
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• pp.3637-3643
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• 2012

Objective: Non-homologous end joining (NHEJ) is a pathway for repairing DNA double-strand breaks. Recent publications indicated that XRCC5, XRCC6 and XRCC7 genes may participate in the pathogenesis of breast cancer. The aim of this Human Genome Epidemiology (HuGE) review and meta-analysis was to investigate associations between XRCC5, XRCC6 and XRCC7 genetic polymorphisms in the NHEJ pathway and breast cancer risk. Methods: Studies focusing on the relationship between genetic polymorphisms in XRCC5, XRCC6 and XRCC7 genes and susceptibility to breast cancer were selected from the Pubmed, Cochrane library, Embase, Web of Science, Springerlink, CNKI and CBM databases. Data were extracted by two independent reviewers. The meta-analysis was performed with Review Manager Version 5.1.6 and STATA Version 12.0 software. The odds ratio (OR) with 95% confidence interval (95%CI) was calculated based on the extracted data. Results: According to the inclusion criteria, we final included seven studies with a total of 2,864 breast cancer cases and 3,060 healthy controls. Meta-analysis results showed that rs3835 (G>A) and rs828907 (G>T) in XRCC5 gene, and rs132793 (G>A) in XRCC6 gene might increase the risk of breast cancer, while rs132788 G>T and rs6002421 (A>G) might be protective factors. However, there was no relationship between XRCC7 genetic polymorphisms and the risk of breast cancer. Conclusion: This meta-analysis suggests that the rs3835 G>A and rs828907 G>T in XRCC5 gene, rs6002421 (A>G), rs132788 (G>T) and rs132793 (G>A) in XRCC6 gene might be risk factors for breast cancer, while the rs132788 (G>T) and rs6002421 (A>G) in XRCC6 gene might be protective.

• Journal of KIISE:Databases
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• v.35 no.6
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• pp.459-468
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• 2008

A data stream which is a massive unbounded sequence of data elements continuously generated at a rapid rate. Many recent research activities for emerging applications often need to deal with the data stream. Such applications can be web click monitoring, sensor data processing, network traffic analysis. telephone records and multi-media data. For this. data processing over a data stream are not performed on the stored data but performed the newly updated data with pre-registered queries, and then return a result immediately or periodically. Recently, many studies are focused on dealing with a data stream more than a stored data set. Especially. there are many researches to optimize continuous queries in order to perform them efficiently. This paper proposes a query optimization algorithm to manage continuous query which has multiple join operators(Multi-way join) over data streams. It is called by an Extended Greedy query optimization based on a greedy algorithm. It defines a join cost by a required operation to compute a join and an operation to process a result and then stores all information for computing join cost and join cost in the statistics catalog. To overcome a weak point of greedy algorithm which has poor performance, the algorithm selects the set of operators with a small lay, instead of operator with the smallest cost. The set is influenced the accuracy and execution time of the algorithm and can be controlled adaptively by two user-defined values. Experiment results illustrate the performance of the EGA algorithm in various stream environments.

• Journal of KIISE:Databases
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• v.41 no.4
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• pp.226-241
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• 2014

LOD(Linked Open Data) is composed of RDF triples which are based on ontologies. They are identified, linked, and accessed under the principles of linked data. Publications of LOD data sets lead to the extension of LOD cloud and ultimately progress to the web of data. However, if ontologically the same things in different LOD data sets are identified by different URIs, it is difficult to figure out their sameness and to provide trustworthy links among them. To solve this problem, we suggest a Trustworthiness Improving Link Evaluation, TILE for short, technique. TILE evaluates links in 4 steps. Step 1 is to consider the inference property of syntactic elements in LOD data set and then generate RDF triples which have existed implicitly. In Step 2, TILE appoints predicates, compares their objects in triples, and then evaluates links between the subjects in the triples. In Step 3, TILE evaluates the predicates' syntactic property at the standpoints of subject description and vocabulary definition and compensates the evaluation results of Step 2. The syntactic elements considered by TILE contain RDFS, OWL, OWL2 which are recommended by W3C. Finally, TILE makes the publisher of LOD data set review the evaluation results and then decide whether to re-evaluate or finalize the links. This leads the publishers' responsibility to be reflected in the trustworthiness of links among the data published.

• Proceedings of the Korean Information Science Society Conference
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• 2006.06c
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• pp.265-267
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• 2006

사용목적(Purpose)은 최근 개인 프라이버시 보호와 관련하여 데이타 수집과 수집 후 보안관리에 있어서 중요한 요소로 사용되고 있다. W3C(World Wide Web Consortium)는 데이타 제공자가 자신이 방문한 웹 사이트에 개인정보를 제공하는 것을 통제할 수 있도록 하는 표준을 제시하였다. 그러나 데이타 수집 후 유통과정에서 개인정보에 대한 보안관리에 대한 언급이 없다. 현재 히포크라테스 데이타베이스(Hippocratic Databases), 사용목적기반 접근제어(Purpose Based Access Control)등은 W3C의 데이타 수집 메커니즘을 따르고 있으며, 데이타 수집 후 보안관리에 대하여 사용목적 관리와 접근제어 기법을 사용하여 관리를 하고 있으나 사용목적에 대한 표현과 사용목적 관리의 미흡함으로 인하여 그에 따르는 개인정보의 프라이버시 보호에 있어서 효과적인 해결책을 제시하지 못하고 있다. 본 논문은 사용목적의 표현력을 향상시키면서. 사용목적의 효과적인 관리기법을 제시한다. 또한 개인의 프라이버시 보호를 위한 방법으로 사용목적의 분류화를 통해 최소권한의 원칙을 따르는 접근제어 기법을 제시한다. 본 논문에서는 사용목적을 상속적, 시간적 그리고 독립적 구조로 분류화하였으며, 이렇게 분류화된 사용목적에 대한 각기 다른 관리기법을 제시한다. 또한 접근제어의 유연성을 위해 RBAC의 역할계층 구조를 사용하였으며, 일의 최소 단위인 태스크(task)의 최소권한을 얻기 위한 조건으로 몇몇 특성의 사용목적을 사용하여 만족할 경우 태스크를 처리하기 위한 기존 모델보다 향상된 최소사용권한을 제공하는 기법을 제시한다. Interference Contrast)에 의한 내부구조 관찰이 최종 동정기준이 되어야할 것으로 나타났다.cillus로 구성되었다. 한편, DAL세균군(42균주)은 high G+C 및 low G+C gram positive 계통군 이외에도 proteobacteria -subdivision에 속하는 Afipia와 Ralstonia, proteobacteria -subdivision에 속하는 Variovorax, proteobacteria $\beta$-subdivision에 속하는Pseudomonas로 구성되어 계통학적으로 다양한 세균임이 확인되었다. 40%까지 대체가 가능하였으며, 아울러 높은 라이신 부산물의 대체 수준에 있어서 사료효율과 단백질 전환효율을 고려한다면 아미노산 첨가(라이신과 아르지닌)와 중화 효과에 좋은 결과가 있을 것으로 사료된다.의한 적정 양성수용밀도는 각고 5~6cm 크기의 경우 10~15개체가 적합하였다. 수증별 성장은 15~20 m 수층에서 빨랐으며, 성장촉진과 폐사를 줄이기 위해서는 고수온이 지속되는 7~10월에는 20~30m수층으로 채롱을 내려 양성하고 그 외 시기에는 15 m층 내외가 좋은 것으로 나타났다. 상품으로 출하 가능한 크기 인 각고 10 cm이상, 전중량 140 g 내외로 성장시 키기까지는 채묘후 22개월이 소요되었고, 출하시기는 전중량 증가가 최대에 이르는 3월에서 4월 중순이 경제적일 것으로 판단된다.er 90 % of good relative dynamic modulus of elasticity due to fineness of formation caused by the