• 한국정보통신학회:학술대회논문집
• /
• 한국정보통신학회 2021년도 추계학술대회
• /
• pp.397-399
• /
• 2021

본 논문에서는 폐암 세포 증식을 억제하기 위해 멀티모달 시스템 개발에 관한 기본연구를 수행하였다. 광 자극 시스템과 특정한 주파수를 발생시키는 초음파를 이용하여 폐암 세포를 대상으로 자극을 인가하였고, 세포의 증식 억제 효과를 영상화하여 정량적으로 평가하였다. 실험 결과, 초음파와 LED 단일 자극을 인가하였을 때와 동시에 인가하였을 때 폐암 세포의 증식률에서 의미 있는 결과를 보였다.

• 대한조선학회논문집
• /
• 제50권2호
• /
• pp.79-87
• /
• 2013

In this paper, an Euler equation solver based on a Cartesian-grid method and non-uniform staggered grid system is applied to predict the ship motion response and added resistance in waves. Water, air, and solid domains are identified by a volume-fraction function for each phase and in each cell. For capturing the interface between air and water, the tangent of hyperbola for interface capturing (THINC) scheme is used with a weighed line interface calculation (WLIC) method. The volume fraction of solid body embedded in a Cartesian-grid system is calculated by a level-set based algorithm, and the body boundary condition is imposed by volume weighted formula. Added resistance is calculated by direct pressure integration on the ship surface. Numerical simulations for a Wigley III hull and an S175 containership in regular waves have been carried out to validate the newly developed code, and the ship motion responses and added resistances are compared with experimental data. For S175 containership, grid convergence test has been conducted to investigate the sensitivity of grid spacing on the motion responses and added resistances.

• 동의생리병리학회지
• /
• 제25권4호
• /
• pp.603-607
• /
• 2011

The purpose of this study is to investigate the effects of Carthami Flos on interstitial cells of Cajal in the gastrointestinal tract. Many regions of the tunica muscularis of the gastrointestinal (GI) tract display spontaneous contraction. These spontaneous contractions are mediated by periodic generation of electrical slow waves. Recent studies have shown that the interstitial cells of Cajal (ICCs) act as pacemakers and conductors of electrical slow waves in gastrointestinal smooth muscles. We investigated the cytotoxicity activity, antioxidant activity, and pacemaking activity. The cytotoxicity activity was measured by MTT (3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyltetrazolium bromide) assay. Antioxidant activities were determined by DPPH (1.1-diphenyl-2-picrylhydrazyl) radical scavenging capacity assay and DCFH-DA (2,7-dichlorofluorescein diacetate) method. The effects of Carthami Flos on the pacemaker potentials in cultured ICCs from murine small intestine were investigated by using whole-cell patch-clamp techniques at $30^{\circ}C$. The addition of Carthami Flos (5, 10, $30{\mu}g$/ml) depolarized the resting membrane potentials in a concentration dependent manner. These results suggest that the GI tract can be targets for Carthami Flos, and their interaction can affect intestinal motility.

• 대한조선학회논문집
• /
• 제49권6호
• /
• pp.461-468
• /
• 2012

In this study, a Cartesian-grid method based on finite volume approach is applied to simulate the ship motions in large amplitude waves. Fractional step method is applied for pressure-velocity coupling and TVD limiter is used to interpolate the cell face value for the discretization of convective term. Water, air, and solid phases are identified by using the concept of volume-fraction function for each phase. In order to capture the interface between air and water, the tangent of hyperbola for interface capturing (THINC) scheme is used with weighed line interface calculation (WLIC) method which considers multidimensional information. The volume fraction of solid body embedded in the Cartesian grid system is calculated using a level-set based algorithm, and the body boundary condition is imposed by a volume weighted formula. Numerical simulations for the two-dimensional barge type model and Wigley hull in linear waves have been carried out to validate the newly developed code. To demonstrate the applicability for highly nonlinear wave-body interactions such as green water on the deck, numerical analysis on the large-amplitude motion of S175 containership is conducted and all computational results are compared with experimental data.

• 한국해양환경ㆍ에너지학회지
• /
• 제10권4호
• /
• pp.187-192
• /
• 2007

플런징 쇄파에 의해 실린더에 작용하는 충격력을 실험적으로 고찰하였다. 쇄파는 조파기의 구동주파수를 선형적으로 감소시켜 수조의 목표지점에 파랑을 집중시킴으로써 생성되며, 쇄파의 파형은 등파기울기 스펙트럼을 채택하였다. 실린더와 쇄파 전면의 접촉각이 충격력에 미치는 영향을 고찰하기 위해 3개의 경사각을 적용하였으며, 압력 분포 및 정점 값에 대한 실린더 직경의 영향을 살피기 위해 3개의 서로 다른 직경을 갖는 실린더가 사용되었다. 충격 압력의 최대 값을 찾기 위해 실린더를 수조 길이방향으로 조금씩 이동하며 총 8개 지점에서 실험을 수행하였다. 실린더 표면의 압력과 합력은 piezo-electric형 압력계와 3축 로드셀을 사용하여 30 kHz의 빈도로 계측하였다. 실린더 직경, 경사각 및 회전각에 따른 정점 충격압력과 충격력의 변화를 분석하였으며, 실린더 표면의 압력분포를 고찰하였다. 실린더의 수조 내 위치 및 실린더 표면의 위치는 정점압력의 크기와 시계열 형상을 지배하는 주요 인자이며, 반면에 실린더 직경과 경사각의 영향은 상대적으로 미미하다. 충격현상은 매우 불안정하기 때문에 동일조건의 반복 실험에서도 계측 값의 넓은 분포가 발생한다.

• Journal of Mechanical Science and Technology
• /
• 제15권3호
• /
• pp.384-391
• /
• 2001

The aerodynamic effects of a 3-dimensional Wing in Ground Effect (WIG) which moves above the free surface has been numerically investigated via finite difference techniques. The air flow field around a WIG is analyzed by a Marker & Cell (MAC) based method, and the interactions between WIG and the free surface are studied by the pressure distributions on the free surface. Waves are generated by the surface pressure distribution, and a Navier-Stokes solver has been employed, to include the nonlinearities in the free surface conditions. The pressure values Cp and lift/drag ratio are reviewed by changing the height/chord ratio. In the present computations a NACA0012 airfoil with a span/chord ratio of 3.0 are treated. Through computational results, it is confirmed that the free surface can be treated as a rigid wavy wall.

• 한국광학회지
• /
• 제3권4호
• /
• pp.239-243
• /
• 1992

KDP 결정에서 2차 고조파가 발생될 때와 질소기체에서 CARS신호가 발생될 때 나타나는 간섭현상을 조사하였다. 비선형 신호들의 위상차이를 주기 위하여 광학유리를 이용하여 제작된 위상변이장치와 고압기체셀을 사용하였으며 각 매질에 대한 가간섭길이를 측정하였다. 특정한 스톡스광의 파장에서 CARS신호가 상쇄간섭을 일으키도록 위상변이장치의 두께를 조정한 후, 넓은 파장영역에서 상쇄간섭된 질소 CARS 스펙트럼을 얻었다. 위상변이장치의 두께를 바꾸면서 상쇄간섭정도의 변화를 관찰하였다.

• 한국가시화정보학회:학술대회논문집
• /
• 한국가시화정보학회 2006년도 추계학술대회 논문집
• /
• pp.145-148
• /
• 2006

In order to design a micro-thruster which controls the altitude of a space vehicle for a very long lifetime, the flow field should be analyzed considering the nozzle geometry and the difference between stagnation and environmental pressures and so on. This paper describes the axisymmetric non-reacted computational results which were carried out to understand the basic flow phenomena according to the high nozzle pressure ratio. The area ratio is about 56 and the diameter of a nozzle exit is about 0.46 inch. The Mach cell and waves are predicted well.

• 천문학회보
• /
• 제45권1호
• /
• pp.55.2-55.2
• /
• 2020

Radio relics in the outskirts of galaxy clusters are interpreted as synchrotron radiation due to the relativistic electrons produced via diffusive shock acceleration (DSA) in shocks with low sonic Mach numbers, Ms ≤ 3 in high beta ICM plasma. Electron injection into the DSA process at such weak shocks is one of the key elements, which has yet to be fully understood. In this study, we explore the nature of kinetic microinstabilities excited in weak quasi-perpendicular shocks through 2D particle-in-cell simulations. We find Alfven-ion cyclotron (AIC), whistler, and mirror instabilities can be triggered by ion and electron temperature anisotropy in the immediate downstream of supercritical shocks with Ms > Mcrit ~ 2.3. In particular, AIC instability causes rippling of the shock surface, which in turn generates plasma waves on multi-scales and faciliates the electron preacceleration. Our results may contribute to understanding the origins of radio relics.

• 한국지구물리탐사학회:학술대회논문집
• /
• 한국지구물리탐사학회 2005년도 공동학술대회 논문집
• /
• pp.223-226
• /
• 2005

동일한 파원에서 발생된 P, SH, SV 파를 3성분 지오폰으로 동시에 기록하는 방법을 연구하기 위해서, 94 m의 측선을 따라 2 m 간격으로 설치한 수신점에서 기록된 24채널 자료를 512 ms동안 기록하였다. 원시자료의 수직성분에는 P파가 초동으로 뚜렷하게 나타나며, 측선방향과 수직한 수평성분은 P파가 약화된 반면 S파의 신호/잡음비가 향상된 모습을 보인다. 토모그래피 역산을 통해 계산된 P파 및 S파의 속도 토모그램을 이용하여 동포아송비의 2차원적 분포를 산출한 결과, 동포아송비는 $0.2{\~}0.3$의 범위로 분포하며, 이는 한번의 타격으로 P파 및 S파의 속도분포와 더불어 및 동포아송비의 2차원적 분포까지 획득할 수 있다는데 큰 의의가 있다고 판단된다.