• Journal of the Korean Institute of Navigation
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• v.15 no.1
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• pp.12-47
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• 1991

This work aims to introduce the concept of microcomputer aided port design simulation methodology including the analysis of the mathematical models to be implemented and apply it to the Third Stage Busan Port Development Project. In the Busan case study, the size of the proposed turning basin of the new terminal, together with the operational strategies of berthing and unberthing, was examined, In addition, the safety on ship's entry and exit through the projected new breakwaters was ascertained. From the application of simulation to the Busan project, it was found that the proposed dredging area was not sufficiently wide enough for the modelled container ship to perform A time unberthing (in which the ship turns to port as she manoeuvres away from N.1. Berth with the assistance of tugs), especially in a strong easterly wind. It is therefore, recommended that Busan pilots should be advised to sue B type unberthing strategy, in which the ship goes astern from no.1 berth tot he turning area in front of No.2 berth(where the ship turns 180 degrees clockwise), especially when the wind is very strong, It is also recommended that a sea buoy be placed outside the new breakwaters, as this was found to improve the safety of ship manoeuvres through the breakwaters significantly . Another recommendation is that the Korean hydrodynamic Office carry out a detailed survey of the currents in the water area near the new breakwaters once they have been constructed. In addition, it is to be recommended that a current meter be placed at the recommended sea buoy to improve the safety of ship manoeuvres which could otherwise be jeopardised by eeroneos current information.

• Journal of Dental Anesthesia and Pain Medicine
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• v.17 no.1
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• pp.21-28
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• 2017

Background: The skin consists of tightly connected keratinocytes, and prevents extensive water loss while simultaneously protecting against the entry of microbial pathogens. Excessive cellular levels of reactive oxygen species can induce cell apoptosis and also damage skin integrity. Propofol (2,6-diisopropylphenol) has antioxidant properties. In this study, we investigated how propofol influences intracellular autophagy and apoptotic cell death induced by oxidative stress in human keratinocytes. Method: The following groups were used for experimentation: control, cells were incubated under normoxia (5% $CO_2$, 21% $O_2$, and 74% $N_2$) without propofol; hydrogen peroxide ($H_2O_2$), cells were exposed to $H_2O_2$ ($300{\mu}M$) for 2 h; propofol preconditioning (PPC)/$H_2O_2$, cells pretreated with propofol ($100{\mu}M$) for 2 h were exposed to $H_2O_2$; and 3-methyladenine $(3-MA)/PPC/H_2O_2$, cells pretreated with 3-MA (1 mM) for 1 h and propofol were exposed to $H_2O_2$. Cell viability, apoptosis, and migration capability were evaluated. Relation to autophagy was detected by western blot analysis. Results: Cell viability decreased significantly in the $H_2O_2$ group compared to that in the control group and was improved by propofol preconditioning. Propofol preconditioning effectively decreased $H_2O_2$-induced cell apoptosis and increased cell migration. However, pretreatment with 3-MA inhibited the protective effect of propofol on cell apoptosis. Autophagy was activated in the $PPC/H_2O_2$ group compared to that in the $H_2O_2$ group as demonstrated by western blot analysis and autophagosome staining. Conclusion: The results suggest that propofol preconditioning induces an endogenous cellular protective effect in human keratinocytes against oxidative stress through the activation of signaling pathways related to autophagy.

• Journal of the Korean Society of Fisheries and Ocean Technology
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• v.40 no.1
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• pp.37-46
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• 2004

In order to increase fishing efficiencies of the fyke net used in the coast of Jeju Island, water tank experiment was caried out entering and escaping behavior using nets that were reduced to 1/20 of the size of the full scale fyke net and were improved to have antrance structure, and mackerel Scomber japonicus as experimental fish. The results of measurement are as follows : 1. Fish school behavior in the main net was showed two different patterns : swimming in a circle in the right space of the main net and swimming back and forth in ellipse in the right and left space. 2. The swimming speed of mackerel school was 23.9. 12.6 and 32.0cm/sec in the center space, right space of main net and in the mouth 3. The entering rate of fish school was 40% in net with 35cm length of the upper and funnel net in the mouth of fyke model net and 49% in conventional type fyke model net. 4. The escaping rate of fish school was 10% in net with 35cm length of the upper and funnel net in the mouth of fyke model net and 69% in conventional type fyke model net. 5. The remain rate of fish school was 90% in net with 35cm length of the upper and funnel net in the mouth of fyke model net and 31% in conventional type fyke model net.

• Journal of the Korean Society of Fisheries and Ocean Technology
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• v.53 no.4
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• pp.423-429
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• 2017

As invigoration plan of the marine tourism, Busan City has the plan to operate the cruise ship inside of the harbor, but the area has narrow water way with heavy traffic. As a result it is requested to evaluate the safety for the preparation of actual navigation. In this study, the Ship Handling Simulation (SHS) Assessment was conducted, which is regulated by the Maritime Traffic Safety Audit Scheme (MTSAS) in compliance with the Marine Safety Law and the Maritime Traffic Risk Assessment System based on the Electronic Chart Display and Information System (ECDIS). The proximity assessment, control assessment and subjective assessment were implemented, which is enacted by the Marine Safety Law by using the SHS. In the case of proximity assessment, the probability of trespass was not analyzed. As the control assessment, the swept path was measured at 11.7 m and 11.5 m for port entry and port departure respectively, which exceeded the width of the model vessel, 10.4 m over; it was considered as a marginal factor. As a result of the subjective evaluation of the navigator, there would be no difficulty on ship maneuvering by paying particular attention to the mooring vessel nearby the Busan Bridge and Yeongdo Bridge as well as the coming vessel from the invisible sea area when the vessel is entering and departing the port. The Marine Traffic Risk Assessment System analyzed as [Cautious] level until the vessel passed the Busan bridge and the curved area at 5 kts and it became to [Dangerous] level from where it left 75 m to the Busan Bridge. When the vessel passed the Busan Bridge and the curved area at 10 kts and entered the narrow area, it indicated the [Dangerous] level and became to [Very dangerous] level from where it left 410 m to the Busan bridge. In conclusion, the vessel should maintain at the speed of 5 kts to reduce the risk when it passes this area.

• Journal of Korea Port Economic Association
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• v.30 no.2
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• pp.113-132
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• 2014

With the global warming phenomenon, the deep sea water area that fishing vessels can enter and operate is ever widening. For example, the Arctic Ocean recently has overall competitive advantages due to having many deep-sea fish stocks. The North Pacific region is a strategic coastal district, the closest access point of Arctic Ocean. For Korean fishing vessels which now operate in North Pacific region, and want to entry the Arctic Ocean, the analysis of technical efficiency is needed for preparing the better industry's future. This paper aims to analyze the relative efficiency, and select the low effective deep-sea fishing vessels in the North Pacific, and to suggest their desirables strategies. As a research methodology, Data Envelopment Analysis (DEA) and Malmquist Index are applied to 16 fishing vessels for the periods(2009 to 2013). To draw out the efficiency of targeted deep-sea fishing vessels, gross tons, horsepowers, and operating days are used as input variables while total catch stands for an output variable. As a result, CCR efficiency, BCC efficiency and scalability efficiency are measured to be 0.8405, 0.9484 and 0.8858 respectively for 5 years (2009 to 2013). In conclusion, 38% of total tons, 36% of horsepowers and 29% of operating days each fishing vessel should be reduced to keep their competitive powers.

• Membrane Journal
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• v.8 no.4
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• pp.203-209
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• 1998

The cutting oil emulsion microfiltration was carried out on dead-end call and crossflow systems equipped with 0.22 $\mu$m GVHP Millipore and 0.2 m stainless steel Mott microfiltration membranes, respectivdy. The oil drop size in the emulsion was varied from 0.07 to 0.22 $\mu$m. Cake filtration(CFM) and standard pore blocking models(SPBM) were applied to predict the permeation flux. The permeation fluxes of 0.01 vol% oil emulsion followed CFM for dead-end system very well under the condition of 400 rpm and below 100 kPa. The SPBM was, however, suitable for the permeation flux at 400 rpm and above 150 kPa. The oil layer on the membrane surface was destroyed and reproduced repeatedly as operating pressure was suddenly changed from 60 to 200 kPa, and then returned to 60 kPa. Also, we estimated the critical entry pressure(CEP) which is changed from CFM to SPBM, and CEP for dead-end system was around 100 kPa. The CEP increased from around 100 to 150 kPa for the crossflow system as the oil concentration increased from 0.01 to 0.03 vol% when Reynolds number was 7080.

• Journal of Life Science
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• v.15 no.4 s.71
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• pp.626-632
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• 2005

The polyamines are essential components of all eukaryotic cells and absolutely necessary for cell growth. In the present study, the cytoprotective role of polyamine was characterized. When $Ac_2F$ rat liver cells were treated with 1M 2,2'-azobis (2-amidinopropane) dehydrochloride (AAPH), a water soluble free radical initiator, viability of the cells was noticeably decreased due to the increase of reactive oxygen species (ROS). The cytotoxic effect of AAPH as well as ROS generation were significantly inhibited by the treatment of polyamines. Among polyamines, especially spermine at $20{\mu}M$ concentration exerted over $45\%$ inhibition of AAPH-induced ROS generation. Western blotting was performed to determine whether superoxide dismutase(SOD) or catalase (CAT) expression was involved in oxidative stress. The AAPH treatment blocked both SOD and CAT protein expressions. Spermine could recover those protein expressions to the untreated control levels. According to the result of cycline E measurement, AAPH might block the entry of the cells into S phase of the cell cycle. The reduced expression of cyclin E protein could be fully recovered by the addition of spermine. The antioxidative effects of spermine was also further proved by the apopotitic morphological analysis using ethidium bromide and acridine orange.

• Journal of the Korean Institute of Navigation
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• v.24 no.1
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• pp.1-12
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• 2000

The ships over the certain navigation area or her length are required to carry charts under the relevant laws. Charts are indispensible to the ships and fishing vessel, because their crew should know the water depth and location of obstacle in order to avoid danger in the navigation and fishing area. But it was found that many ships do not carry proper charts onboard according to the research marine accidents files of marine accident inquiry agency, and questionnaire survey. Consequently, many ships run aground on the coast and port. This study examined the present status of the coastal ship and the fishing vessels, and explained some problems in the aspect of the covering area, the place, the number of the selling agent and adjoining chart, as well as the geographical and traffic density, the crew on board the ship's characteristics, and so on. In this study we propose the way to solve the problem. firstly, the category of the fishing vessel which should carry the chart on bard under the related laws are required to be lowered to 10 gross tons. Besides a ship inspector should examine if the charts covering the area where to navigate even when the temporary inspection is done are carried on board property. Secondly, the inspection body or the controlling office of ship's entry and departure should check throughly whether the ships concerned carry the chart on board. Thirdly the fishing vessels should used the fishing charts, and the body concerned should train the offices about how to use chart, especiany the difference between Tokyo datum and WGS-84 datum. Fourthly the customized chart such as an atlas like a map, a calenda-type chart, a small chart, as a coated chart needs to be publish for the safety of small ship and fishing vessel. Fifthly, it is advisable to draw a recommended course in the route where the coastal navigate mainly and in the narrow channel, The adjoining area should be improved, as well as the qualify of the chart paper. Sixthly, publication of additional new chart in the southern part of East Sea, the eastern part of South Sea, the western part of South Sea and middle part of Yellow Sea near Incheon port should be thought over. Seventhly, the number of chart selling agent should be increased for the sake of purchaser in proportion to the number of port, and small correction of charts in selling agent must be carried out completely.

• Journal of Navigation and Port Research
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• v.44 no.3
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• pp.174-180
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• 2020

With the removal of underwater obstacles in the Busan New Port, the water depth of the pier has been secured up to 17m, and the port authority is constantly responding to the trend of container vessels becoming larger. Also, in 2020, 24,000TEU class container ships are entering to the port, and it is planned to secure the depth in the port to 23 m later in line with this trend. Mega container ships must check in advance the factors to be considered depending on the situation at the time, and for this, it is judged that information sharing among stakeholders is necessary. In this paper, to understand the effect of the corresponding route because of the mega container ships, a transit safety evaluation was conducted based on statistical data on ship entry and departure and maneuver characteristics of corresponding ships. The result showed that the transit of the mega container ships has increased up to 8.4% comparing to the risk of 4,000TEU class container ships. Additionally, safety measures such as minimum safety depth and tug operation plans were presented by gathering opinions on operational characteristics from the perspective of pilotage for safe transit in the Busan New Port area. Through this, it is considered that it will be possible to contribute to the prevention of accidents when entering and leaving the Busan New Port.

• Korean Journal of Construction Engineering and Management
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• v.19 no.5
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• pp.10-21
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• 2018

This study analyzes difficulties of enterprise activities in Chinese construction market by surveys on early entrants and interviews with experts. This study also suggests future strategy to enter the market by using inducement coefficient model. Korean construction companies in China are under heavy pressure to maintain requirement of licenses, despite recent deregulation. They are in dire predicament for market entry due to the Foreign Direct Investment System. It is almost impossible to participate in public projects and also it is not easy to do PPP projects. Therefore, Korean government should make more efforts to solve those issues through negotiations in FTA and GPA. For future expansion in Chinese construction market, it is highly recommended to boost cooperation models between Korea and China according to the empirical results of inducement coefficient model. Korean companies should collaborate with Chinese companies in some fields: smart city, environment and water treatment. Also, Korean government should support Korean companies by diplomatic means such as requesting for further opening of China's market. In GPA or GATS negotiation, Korean government should ask Chinese government that Korean companies can obtain order independently (without joint venture with Chinese companies) in China. Lastly, Korean construction companies should participate in construction projects ordered by international organizations such as ADB, AIIB.