• 제목/요약/키워드: Water-damaged

검색결과 679건 처리시간 0.027초

손상된 핵산의 구조와 분자동력학적 특성 (Conformational and Molecular Dynamical Properties of Damaged DNA)

  • 박경래;드 로스 산토스 카를로스
    • 약학회지
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    • 제54권1호
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    • pp.67-74
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    • 2010
  • Some of the benzopyrene (BP)-DNA adduct are known to build intercalated motif between flanking base pairs in damaged DNA depending on the structural condition. The size of benzopyrene itself is definitely not comparable with any of the DNA bases and thus the question whether the lesion of some base pair by insertion of benzopyrene can happen with or without a dramatic distortion of the helical structure is a highly interesting theme. In this work we used a molecular dynamics simulation based on the theory of molecular mechanics. The specific consequences about the structural properties of the intercalated structures and benzopyrene motif in minor groove of the double helix are deduced after 5 ns simulation time.

손상된 콘크리트 구조물에 에폭시수지를 이용한 보수·보강효과에 대한 연구 (A Study on the Repair and Strengthening Effects of Epoxy Grout for the Damaged Concrete Structure)

  • 신성우;조태관
    • 한국구조물진단유지관리공학회 논문집
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    • 제1권1호
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    • pp.125-132
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    • 1997
  • This study was intended to investigate the effects of epoxy grout on compressive strength for damaged concrete structures. For this purpose, concrete molds were manufactured and tested for compressive strength at 28 days after water curing. Two kinds of Korea-made and one Japan-made epoxy grouts were injected into the broken concrete molds with the automatic low-pressure injecting method or the hand injecting method.

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가상 지진해일에 의한 동해안에서의 피해 예측 (The prediction of maximum wave height for virtual tsunami in the eastern coast of the Korea)

  • 심주열;최문규;조용식
    • 한국방재학회:학술대회논문집
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    • 한국방재학회 2008년도 정기총회 및 학술발표대회
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    • pp.229-232
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    • 2008
  • The Central East Sea Tsunami caused huge damage to the eastern coast of the Korean Peninsula, eapecially Imwon port was damaged relatively strongly beacause of water depth variation which makes the wave concentration on this port. there are many virtual tsunami in east sea which has a possibility of happening. So, it is very important to expect the region which may be damaged by vritual tsunmis. In this study, modified dispersion-correction terms are used. The modified scheme has the advantage of using the constant spatial grid size and time step size even in real topography. Dynamic linking technique and staggered grid system are used. Using this model some cases of virtual tsunami was simulated and check the region which is occured maximum wave heights on the eastern sea of the Korean peninsula.

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Effects of Petrolatum and Glycerin on Acetone Damaged Canine Skin Barrier

  • Oh, Won-Seok;Oh, Tae-Ho
    • 한국임상수의학회지
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    • 제25권6호
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    • pp.466-470
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    • 2008
  • The purpose of this study is to investigate whether the effects of topically applied petrolatum and glycerin on the barrier repair of acetone-induced skin damage in 6 beagle dogs. To confirm the effects of petrolatum and glycerin on acetone disrupted skin models, we performed to evaluate the characteristics of transepidermal water loss and SC hydration and scanning electron microscopic observations. TEWL and SC hydration measurements were carried out 3, 6, 12, 24, 48h after applying petrolatum and glycerin during recovery from acute disruption. Our results showed that there were some different effects between petrolatum and glycerin on the acetone damaged skin such as barrier function repair process and SC hydration status. The results indicate that the significant improvement could be observed in glycerin apply more than petrolatum after acetone damages, and further study will be required.

유기안료 농도를 이용한 동절기 초기동해 피해 콘크리트의 깊이 진단 (Diagnose of Impaired Depth due to Early Frost Damage of the Concrete Using Organic Pigment Concentration)

  • 최윤호;임군수;김상민;김종;한민철;한천구
    • 한국건축시공학회:학술대회논문집
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    • 한국건축시공학회 2020년도 봄 학술논문 발표대회
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    • pp.167-168
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    • 2020
  • In this study, we attempted to present a method for diagnosing the depth of the early frost damage concrete using organic pigments under the cold weather. As a result, it is considered that the organic pigment did not penetrate into the voids of the concrete that had been damaged by the early frost damage and only the surface was adhered. Therefore, when fine particles that can be melted in water and pass through voids are used, it is analyzed that it can penetrate damaged part of the concrete.

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CASE STUDY ON SEVERELY-DAMAGED REINFORCED EARTH WALL WITH GEO-TEXTILE IN HYOGO, JAPAN Part I: Site Investigation into the cause of damage

  • Jung, Min-Su;Kawajiri, Shunzo;Hur, Jin-Suk;Shibuya, Satoru
    • 한국지반공학회:학술대회논문집
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    • 한국지반공학회 2010년도 추계 학술발표회 3차
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    • pp.3-10
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    • 2010
  • Case study was carried out on the interpretation of the mechanical behavior of a severely damaged reinforced earth wall comprising geotextile with the concrete panel facing. In this part I, the outline of the damaged reinforced earth wall is in detail described. The background and cause of the damage are discussed based on the results of site investigation. The engineering properties of the fill were examined by performing various in-situ and laboratory tests, including the surface wave survey (SWS), PS-logging, RI-logging, soaking test, the direct shear box (DSB) test, bender element (BE) test, etc. The background as well as the cause for the damage of the wall may be described such that i) a considerable amount of settlement took place over a 3m thick weak soil layer in the lower part of the reinforced earth due to seepage of rainfall water, ii) the weight of the upper fill was partially supported by the geo-textile hooked on the concrete panels (n.b., named conveniently "hammock state" in this paper), and iii) the concrete panels to form the hammock were severely damaged by the unexpectedly large downwards compression force triggered by the tension force of the geotextile. The numerical simulation for the hammock state of the wall, together with counter-measures to re- stabilize the wall is subsequently described in Part II.

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손상 선박의 기름 유출량 예측을 위한 CFD 시뮬레이션 (Prediction of Oil Outflows from Damaged Ships using CFD Simulations)

  • 문요섭;박일룡;김제인;서성부;이승국;최혁진;홍사영
    • 해양환경안전학회지
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    • 제28권2호
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    • pp.394-405
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    • 2022
  • 본 논문은 CFD 해석법을 이용한 단일선체 및 이중선체 선박의 손상에 따른 기름 유출량 추정 결과를 소개한다. 수치해석 기법으로 다상유동 해석법을 사용하고 기름 유출 유동에 대한 다양한 수치해석적 조건의 변화에 대한 영향을 조사하였다. 좌초 또는 충돌에 의한 다양한 손상 조건에서의 기름 유출량의 변화를 해석하였으며 실험 결과를 통해 검증하였다. 본 논문의 수치해석 결과는 단일선체와 이중선체의 기하학적 특성을 따라 실험 결과와 잘 일치하였다. 특별히 물과 기름의 복잡한 상호작용이 나타나는 이중선체의 기름 유출 상황도 실험과 동일하게 타당하게 예측하였다. 본 연구를 통해 사고 선박의 기름 유출량 추정에 필요한 CFD기법을 정립할 수 있었다.

지의류(地衣類) 추출물을 섭취한 흰쥐 간의 산화적 인산화 과정 및 대사물 측정(II) (Effect of Water Soluble Extract of Lichens on Oxidative Phosphorylation and Level of Metabolite in Rat Liver)

  • 안미정;서정순;이인자;조성희
    • 한국식품영양과학회지
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    • 제14권2호
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    • pp.145-150
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    • 1985
  • 지의류(lichens) 수용성 추출물에 약리적인 효과를 알기위해 $CCl_4$로 흰쥐의 간손상을 유도시킨 후 단기간, 장기간 사육시켜서 간장조직의 mitochondrial respiration측정을 하였고 간장조직내의 lactate, malate와 fumarate glutamate, 혈청 glucose 및 간장조직의 glucose-6-phosphatase의 활성도를 측정하였다. 그 결과 급성 만성의 간장애를 받은 쥐에서 4가지호흡지수(state 3 respiration P/O ratio, respiratory control, 합성된 ATP)로 측정된 mitochondrial respiration 기능이 지의류(lichens) 추출물을 섭취한 실험군이 대조군 보다 높았고, serum glucose, 간장내의 lactate, glutamate, malate와 fumarate및 glucose-6-phosphatase 활성도 실험군이 높은값을 나타내었다. 이것으로 지의류추출물은 간장조직의 mitochondrial respiration에 대해 보호작용과 해당과정을 촉진하는 작용이 있다는 것으로 추정된다.

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대형매트기초의 관통균열 보수시 WATER JET을 이용한 천공과 저면보수에 관한 연구 (When mend piercing crack of large size mat basis, study of perforation and vottom repair that use water jet)

  • 박성우;한송수;이상헌;박찬규
    • 한국콘크리트학회:학술대회논문집
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    • 한국콘크리트학회 2003년도 가을 학술발표회 논문집
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    • pp.577-580
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    • 2003
  • Problem of repairing by boring is that it deteriorates stabelety and durability of structure by permeation of seawater from underneath after damage and repair of reinforcing rod regarding of spot. The purpose of this study is to improve the porblem by using the repair method of general boring to mend the of large mat basis. Direction of thes experiment is to apply the new repair material and the method to control the blazing fire factor caused by the crack from the foundation of large mat and also to estimate it's integrity. New method of construction is method of contruction that do speace scurity in vertical drilling and bottom useing water jet. New material used bantonite and rubberized asphalt. Test result existent repair method of construction large size mat basis perforation is difficult and reinforcing rod can be damaged coule there were a lot of problems with re-water leakage of crack repair region, but overcomes existent short coming by method that apply in this study.

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Non-dimensional analysis of cylindrical objects freely dropped into water in two dimensions (2D)

  • Zhen, Yi;Yu, Xiaochuan;Meng, Haozhan;Li, Linxiong
    • Ocean Systems Engineering
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    • 제10권3호
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    • pp.267-287
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    • 2020
  • The dropped objects are identified as one of the top ten causes of fatalities and serious injuries in the oil and gas industry. It is of importance to understand dynamics of dropped objects under water to accurately predict the motion of dropped objects and protect the underwater structures and facilities from being damaged. In this paper, we study non-dimensionalization of two-dimensional (2D) theory for dropped cylindrical objects. Non-dimensionalization helps to reduce the number of free parameters, identify the relative size of effects of force and moments, and gain a deeper insight of the essential nature of dynamics of dropped cylindrical objects under water. The resulting simulations of dimensionless trajectory confirms that drop angle, trailing edge and drag coefficient have the significant effects on dynamics of trajectories and landing location of dropped cylindrical objects under water.