• 한국한의학연구원논문집
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• 제1권1호
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• pp.509-520
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• 1995

The effect of water extract of antler on serum level of female hormones was investigated in ovariectemized rats. Sprague-Dawley rats were ovariectomized(ox). After a further 40 days the animals were administrated with water extract of antler (625mg/kg daily) for 10, 20 and 30 days, respectively. Serum level of estradiol, progesterone, leutenizing hormone and follicle stimulating hormone were measured. Significant increase of serum estradiol level was elicited at 20 and 30 days after treatment with water extract of antler, respectively, Associated with the increase of serum estradiol level, there was a concomitant decrease in serum follicle stimulating hormone level. Serum progesterone level was also significantly increased at 30 days after treatment with water extract of antler. Although serum leutenizing hormone level of ox rats treated with water extract of anther was slightly lower than that of untreated ox rats, the decrease was not significant.

• Nutrition Research and Practice
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• 제7권2호
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• pp.96-102
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• 2013

Obesity, an intractable metabolic disease, currently has no medical treatment without side effects, so studies have been actively carried out to find natural compounds that have anti-obesity activity with minimum side effects. In this study, the anti-obesity effects of water extracts of seven Capsicum annuum L. varieties being Putgochu (Pca), Oyee gochu (Oca), Kwari putgochu (Kca), Green pepper (Gca), Yellow paprika (Yca), Red paprika (Rca) and Cheongyang gochu (Cca), were examined through the evaluation of lipoprotein lipase (LPL) mRNA expression level in 3T3-L1 cells (mouse pre-adipocytes). After capsaicin elimination by chloroform defatting, freeze-dried powder of Cca was treated to 3T3-L1 cells and anti-obesity effects were examined by determining the LPL mRNA level using the RT-PCR method. Of the primary fractions, only proven fractions underwent secondary and tertiary refractionating to determine anti-obesity effects. From seven different Capsicum annuum L., there was a significant decrease of the LPL mRNA expression level of 50.9% in Cca treatment compared to the control group. A significant decrease of the LPL mRNA expression level was shown in primary fractions (Fr) 5 (36.2% decrease) and 6 (30.5% decrease) of the Cca water extracts. Due to the impurities checked by UPLC chromatography, Fr 5 and 6 were refractionated to determine the LPL mRNA expression level. Treatment of Fr 6-6 (35.8% decrease) and Fr 5-6 (35.3% decrease) showed a significant decrease in the LPL mRNA expression level. When analyzed using UPLC, major compounds of Fr 6-6 and Fr 5-6 were very similar. Subsequently, we refractionated Fr 6-6 and Fr 5-6 to isolate the major peak for structure elucidation. Treatment of Fr 5-6-1 (26.6% decrease) and Fr 6-6-1 (29.7% decrease) showed a significant decrease in the LPL mRNA expression level. Consequently, the fractions may have a possibility to ameliorate obesity through the decrease of the LPL mRNA expression level.

• 한국식생활문화학회지
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• 제4권3호
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• pp.253-256
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• 1989

In order to study the mechanism of the parts of omiza (Schizandra chinensis baillon) on metabolism in normal rats, the metabolites and enzyme activities both in serum and liver were determined. The rats were treated with water extract of the parts of omiza and the results showed a significant decrease of GOT, Glucose (excepted for water extract of fruits), Urea nitrogen, and increase of LDH in serum. Free fatty acid level tended to decrease in serum of rats treated with water extracts of fruits and endocarps and increase in seeds extract treated group. Serum GPT level was unchanged. The level of hapatic metabolites and enzyme activity showed a significant increase, but Pyruvate level was not significantly decreased.

• Asian-Australasian Journal of Animal Sciences
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• 제13권11호
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• pp.1536-1541
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• 2000

The present study was carried out to measure changes of feed intake and thirst level caused by water deprivation in goats fed on dry feed and to elucidate the relationship between those two parameters. Water deprivation significantly (p<0.01) decreased cumulative feed intake and rate of eating at 30, 60, 90 and 120 min, respectively, after feed presentation. Cumulative feed intake, after completion of 2 h feeding, was reduced by about 20, 21 and 64 % due to water deprivation during feeding for 2 h (WD2), for 22 h (WD22) and for 46 h (WD46), respectively, compared to free access to water (FAW). Compared to the FAW, WD2, WD22 and WD46 increased thirst level by about 5, 5 and 9 times, respectively. Mean thirst level (X, g/30 min) was negatively correlated with cumulative feed intake (Y, g DM) after completion of 2h feeding (Y=1302-0.2 X, $r^2=0.97$, p<0.05). Water deprivation depressed plasma volume and there was a significant positive regression between plasma volume (X, ml) and cumulative feed intake (Y, g DM) after completion of 2h feeding (Y=-1003+0.6 X, $r^2=0.99$, p<0.01). Mean plasma osmolality (X, mOsmol/l) correlated significantly and negatively with cumulative feed intake (Y, g DM) after completion of 2h feeding (Y=27004-84.9 X, $r^2=0.95$, p<0.05). In conclusion, a decrease of feed intake during water deprivation is mainly due to an increase of thirst level quantitatively, and the act of feeding itself induces thirst more than the length of water-deprivation periods in goats fed on dry feeds. The present findings suggest that plasma osmolality and plasma volume which affect thirst level are involved in the decrease of feed intake in water-deprived goats.

• 한국농공학회논문집
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• 제53권6호
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• pp.51-58
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• 2011

The objective of this study is to identify whether or not the ground water level is decreasing. We suggest a method of estimating the change in groundwater level using newly developed groundwater pumping station data. The Goseong area located in Gyeongnam province was selected considering three factors. First, this area demands relatively large amount of irrigation water because most of the land is used as a paddy field and the proportion of the paddy field within total arable land is increasing. Second, groundwater level data in nearby area are available since these are monitored by Water Management Information System (WAMIS). Third, many groundwater pumping stations have been developed in this area in order to overcome droughts thus detail information for pumping stations are available. Regression results indicate groundwater level has been decreased for over 20 years. This decreasing trend is due to the shortage of surface irrigation water which was caused by the decrease in rainfall.

• 한국양식학회지
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• 제12권3호
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• pp.221-228
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• 1999

The effects of sparp changes of water temperature (WT) on the stree response and physiological change of the cultured olive flounder (Paralichthys olivaceus) were examined by manipulating WT (3 patterns) in a running seawater culture system. In the first group (Exp. I), the WT was decreased from 18$^{\circ}C$ to 11$^{\circ}C$ within 6 hours and increased back to the original WT quickly. WT was decreased from 2$0^{\circ}C$ to 11$^{\circ}C$ within 5 hours and main-tained at 11$^{\circ}C$ for 10 hours. and then increased to 2$0^{\circ}C$ in the second group (Exp. II). In the third group(Exp. III) WT was decreased to 11$^{\circ}C$ within 5 hours (type A) or 10 hrs. (type B). In Exp. I and III, the level of serum cortisol was increased from 2.5$\pm$0.3 ng/ml and 2.6$\pm$0.9 ng/ml to 13.6$\pm$3.0 ng/ml and 12.4$\pm$3.2ng/ml, respectively, with WT decrease. However, no consistent tendency in the change of serum glucose level was shown according to WT decrease. In Exp. III, the glucose level of fish in type A was decreased until 5 hours and increased at 7 hours, then decreased until 12 hours where as the glucose level in type B was decreased until 5 hours and stayed at the level of 15.7 mg/dl. The serum osmolality was reduced with WT decrease and the response of serum electrolytes in this experiment conflicted, and a tendency in total protein, AST and ALT was not found following WT decrease. In conclusion, olive flounder responded to the stress caused by WT decrease and acclimated to this condition when the lower temperature was maintained. But there was no stress response in the blood of olive flounder when WT was increased. On the other hand, the degree of stress response in olive flounder was various according to the range and gradient of WT change.

• 한국수자원학회:학술대회논문집
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• 한국수자원학회 2006년도 학술발표회 논문집
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• pp.546-551
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• 2006

It considered the population decrease and becoming older in age of the Rural area and operates by unmaned-non power which self-controlled gate developed. The operational principal used a buoyancy and when water level in the canal arrived to the set water level, in order for gate to be opened. The plate in order to fix to the shape in the canal which begs, it did in the quadrilateral and the rainfall it is sour intensively, canal bank comfort plate in order to ascend completely, it designed. The result which establishes Self-controlled gate, the gate upstream 1km until degree there was water level synergistic effect. It developed 4 as the research project and it established in Ah San city, and it establishes the Self-controlled gate of $B3.2m{\times}H2.4m$ size in Damyang and 100ha it does water supply in the rice field.

• Applied Biological Chemistry
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• 제41권4호
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• pp.228-234
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• 1998

An adaptive measure of photosynthetic cells to a condition identified with a reduction of cellular energy charge, caused by water deficit-induced impairment of photosynthetic ATP production, was investigated using hydroponically cultured rice seedlings. Water stress treatment of the seedlings resulted in a marked decrease in cellular ATP level, a significant increase in the content of NAD(H) and concurrent decrease in that of NADP(H) in shoots, which accompanied a decrease in the activity of NAD kinase (EC 2.7.1.23) that specifically converts NAD(H) to NADP(H). The decline in the enzyme activity was particularly evident in the $Ca^{2+}/calmodulin-dependent$ kinase, the major form of NAD kinase in plants, whereas the level of active calmodulin remained unchanged during water deficit. The ratio of $NADP^+$ to NADPH was maintained nearly constant and no increases were seen in the level of $H_2O_2$ and the activities of $superoxide/H_2O_2-detoxifying$ enzymes in shoots stress-treated for two days. Based on these results, it may be suggested that rice plants take a strategy to cope with an adverse situation of limited photophosphorylation created by water deficit in that cells facilitate ATP production through glycolysis and oxidative phosphorylation; in doing so, rice cells suppress NAD kinase activity, consequently up-sizing the NAD(H) pool at the expense of the NADP(H) pool. Several parameters associated with the stress symptoms are also of implicative that there is no overproduction of superoxide radical or the related active oxygen at least in rice seedlings.

• 한국지하수토양환경학회지:지하수토양환경
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• 제21권6호
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• pp.22-35
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• 2016

Global climate change could have an impact on hydrological process of a watershed and result in problems with future water supply by influencing the recharge process into the aquifer. This study aims to assess the change of groundwater recharge rate by climate change and to predict the sustainability of groundwater resource in Pyoseon watershed, Jeju Island. For the prediction, the groundwater recharge rate of the study area was estimated based on two future climate scenarios (RCP 4.5, RCP 8.5) by using the Soil Water Balance (SWB) computer code. The calculated groundwater recharge rate was used for groundwater flow simulation and the change of groundwater level according to the climate change was predicted using a numerical simulation program (FEFLOW 6.1). The average recharge rate from 2020 to 2100 was predicted to decrease by 10~12% compared to the current situation (1990~2015) while the evapotranspiration and the direct runoff rate would increase at both climate scenarios. The decrease in groundwater recharge rate due to the climate change results in the decline of groundwater level. In some monitoring wells, the predicted mean groundwater level at the year of the lowest water level was estimated to be lower by 60~70 m than the current situation. The model also predicted that temporal fluctuation of groundwater recharge, runoff and evapotranspiration would become more severe as a result of climate change, making the sustainable management of water resource more challenging in the future. Our study results demonstrate that the future availability of water resources highly depends on climate change. Thus, intensive studies on climate changes and water resources should be performed based on the sufficient data, advanced climate change scenarios, and improved modeling methodology.

• 한국철도학회:학술대회논문집
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• 한국철도학회 2008년도 추계학술대회 논문집
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• pp.789-795
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• 2008

Slope stability is affected by various factors. For safety management of slopes, monitoring systems have been widely constructed along railway lines. The representative data from the systems are variations of ground profile such like ground water level and pore water pressure etc. and direct displacement measured by ground clinometer and tension wire sensor. Slopes are mainly effected by rainfall and rainfall causes the decrease of factor of safety(FOS). Because FOS varies linearly by the variation of ground water level and pore pressure, it has a weak point that could not define the time and proper warning sign to secure the safety of the train. In this study, alternative of FOS such as reliability index and probability of failure is applied to slope stability analysis introducing the reliability concept. FOS, reliability index, probability of failure and velocity of probability of failure of the slopes by variation of ground water level are investigated for setting up the specification of safety management of slopes. By executing case study of a slope(ILLO-IMSUNGLI), it is showed to be applied to specification of safety management.