• Title/Summary/Keyword: Water Channels

Search Result 651, Processing Time 0.028 seconds

Ameliorating Effects of Sulfonylurea Drugs on Insulin Resistance in Otsuka Long-Evans Tokushima Fatty Rats

  • Park, Jeong-Kwon;Kim, Sang-Pyo;Song, Dae-Kyu
    • The Korean Journal of Physiology and Pharmacology
    • /
    • v.12 no.1
    • /
    • pp.7-12
    • /
    • 2008
  • OLETF (Otsuka Long-Evans Tokushima Fatty) rats are characterized by obesity-related insulin resistance, which is a phenotype of type 2 diabetes. Sulfonylurea drugs or benzoic acid derivatives as inhibitors of the ATP-sensitive potassium $(K_{ATP})$ channel are commercially available to treat diabetes. The present study compared sulfonylurea drugs (glimepiride and gliclazide) with one of benzoic acid derivatives (repaglinide) in regard to their long-term effect on ameliorating insulin sensitivity in OLETF rats. Each drug was dissolved and fed with drinking water from 29 weeks of age. On high glucose loading at 45 weeks of age, response of blood glucose recovery was the greatest in the group treated with glimepiride. On immunohistochemistry analysis for the Kir6.2 subunit of $K_{ATP}$ channels, insulin receptor ${\beta}$-subunits, and glucose transporters (GLUT) type 2 and 4 in liver, fat and skeletal muscle tissues, the sulfonylurea drugs (glimepiride and gliclazide) were more effective than repaglinide in recovery from their decreased expressions in OLETF rats. From these results, it seems to be plausible that $K_{ATP}$-channel inhibitors containing sulfonylurea moiety may be much more effective in reducing insulin resistance than those with benzoic acid moiety. In contrast to gliclazide, non-tissue selectivity of glimepiride on $K_{ATP}$ channel inhibition may further strengthen an amelioration of insulin sensitivity unless considering other side effects.

Landscape Characteristics and Suggestions in Chinese Traditional Village - Cases Study of Ping-shan Village - (중국 전통마을의 경관 특성과 시사점 - 병산촌을 대상 지역으로 -)

  • Huai, Kang;Jang, Byoung-Kwan;Yun, Ju-Cheul
    • Journal of Korean Society of Rural Planning
    • /
    • v.22 no.2
    • /
    • pp.67-75
    • /
    • 2016
  • This Research was carried out to investigate landscape characteristics of the traditional Chinese village through the landscape analysis. The Purpose of this study was to offer suggestions for improving Korea's traditional village scenery. This research was conducted by analysis about an important component of the landscape in Ping-shan traditional village. It was studied natural landscape, life landscapes, agricultural production landscapes and symbols landscape. This study was carried out through literature research, field research and interviews. The results of Chinese traditional village's landscape characteristic was First, Ping-shan traditional village was located on the basis of Feng-Shui settings. Second, Ping-shan traditional village was clan-based. Third, It is composed of a large green space on the outskirts of the village. Fourth, Ping-shan traditional village was a typical channel village. Fifth, Ping-shan traditional village was a living landscape with various features. sixth, Ping-shan traditional village was a lot of space to agricultural production, most of the arable land surround village. Suggestions for improving Korea's traditional village scenery are as follows ; First, proposes actively re-design on the base of defense fengshi landscape interpreted as a modern sense. Seconds, when large-scale farmland project is established in Korea, you can expect to gain knowledge from traditional Chinese village spacing. Thirds, It seems to require a study of the public space for festival. in the case of china, ancestral shrine space is center and space for festival. Fourth, It was important to seek knowledge about protection for frequent in flood plains in Korea's traditional village. Ping-shan traditional village was well-known for housing with contact water, connected channels and beautiful defense pond. Fifth, for improving Korea's traditional village scenery, we need to make various focus landscape features. Most of the visitors to Ping-shan traditional village was interested in the big and small beautiful landscapes and shelters.

Hydrodynamic Interaction Effects Between Vessels in Confined Waters (제한수역에서 항행선박이 계류중인 선박에 미치는 간섭영향에 관한 연구)

  • Lee, Chun-Ki
    • Journal of Navigation and Port Research
    • /
    • v.35 no.10
    • /
    • pp.799-804
    • /
    • 2011
  • The hydrodynamic interaction effects between the multi-bodies can not be neglected when vessels are close to each other in congested and confined waters, such as in a harbour or narrow channel. Increase in speed and size of modern vessels make it necessary to consider this interaction effects when designing harbours and navigation channels. In this research, the hydrodynamic interaction effects of the spacing between vessels and water depth along with ship's velocity are summarized and discussed. The goal of this research is to propose a guideline of appropriate speed and distance between passing and moored vessels to avoid the influence of hydrodynamic forces and to navigate safely in confined sea areas.

Establishment of Equi-Distance River Cross Section and Finite Element Mesh Using ArcView and Observed Cross Section (ArcView와 실측단면을 이용한 등간격 하도단면 및 유한요소망 구축)

  • Choi, Seung-Yong;Han, Kun-Yeun
    • Journal of the Korean Association of Geographic Information Studies
    • /
    • v.12 no.4
    • /
    • pp.95-112
    • /
    • 2009
  • The river cross section in the input/output data which are needed in the area of river flow analysis is very important factor. The bottom elevation of actual river cross section has to be correctly reflected to obtain correct results when two dimensional flow analysis is conducted for natural river. But to reflect virtually the bottom elevation of river cross section is impossible. The objective of this study is to suggest a method for creating equi-distance river cross section by using both HEC section and ArcView and constructing the finite element mesh. The main channels of Han and Nakdong river were selected and equi-distance river cross sections constructed in this study have shown good agreement with the observed river cross sections. In addition, high quality finite element meshes can be applied to many areas of study such as finite element analysis for water quality and two dimensional flow analysis using the suggested method for equi-distance river cross sections in this study.

  • PDF

Power Save of Marine Tracker Buoy System Based on NB-IoT for Identification of Fishing Gear (어구 자동 식별을 위한 NB-IoT 기반의 해양 트래커 부이 시스템의 전력 절감)

  • Nam, Sung-Il;Kim, Min-Hoon
    • Journal of Advanced Navigation Technology
    • /
    • v.22 no.6
    • /
    • pp.545-550
    • /
    • 2018
  • Ministry of Oceans and Fisheries declared action plan for the electric fishing gear using real name in order to prevent overusing the fishing gear and to reduce discarded fishing gear. It is needed for a technique that can efficiently transmit the information including the type and location of the fishing gear and the user's real name to the fishing boat and the control center using IoT-based communication. The marine tracker buoy system, which is placed on the water for a long time, transmit the position data and the state data of the buoys to the control center in the ground by using NB-IoT channels. In this paper, we propose the algorithm for the low-power operation of the marine tracker buoy system is proposed and test results of current consumption in the marine tracker buoy system with the proposed algorithm is investigated.

The Maximum Temperature Distribution and Improvement Plan of Protected Horticulture Planning Area in Saemanguem Using CFD Simulation (CFD를 활용한 새만금 시설원예 예정지 최고온도 분포 및 개선방안)

  • Son, Jinkwan;Choi, Deuggyu;Park, Minjung;Yun, Sungwook;Kong, Minjae;Lee, Seungchul;Kim, Changhyun;Kang, Donghyeon
    • Journal of Korean Society of Rural Planning
    • /
    • v.25 no.3
    • /
    • pp.115-128
    • /
    • 2019
  • The A1B scenario predicts that the mean air temperature of South Korea will rise up to $3.8^{\circ}C$ by 2071. However, the effects of ecosystem services are declining because of various environmental problems, including climate change, land use change, stream intensification, non-point pollution, and untreated garbage. Moreover, horticultural sites which have various ecosystem services suffer highly absorbed heat from the heat island phenomenon associated with climate change. Therefore, we analyzed the heat island phenomenon occurring in an protected horticulture estimated area in Saemanguem, South Korea. Using an advanced measurement method, we examined the air temperature change derived from water channels as well as open spaces. The CFD analysis of coverage ratio 85% design showed wind speed of 2.09 m/s and temperature of $38.07^{\circ}C$. At a coverage ratio of 70%, the wind speed was improved to 2.61 m/s and the temperature was improved to $36.89^{\circ}C$. In Alternative 2 with wetlands and trees, the wind speed was 2.71 m/s and the temperature was $35.90^{\circ}C$. When the coverage ratio decreases to 55%, the wind speed increases showing 3.06 m/s and the temperature decreases showing $35.18^{\circ}C$.

Molecular Dynamics Study to Investigate Ion Selectivity of Functionalized Carbon Nanotube Membranes (기능화된 탄소나노튜브 멤브레인의 이온 선택성에 관한 분자동역학 연구)

  • Suk, Myung Eun
    • Membrane Journal
    • /
    • v.28 no.6
    • /
    • pp.388-394
    • /
    • 2018
  • Carbon nanotube (CNT) based membranes are promising candidates for separation membranes by showing high water transport rate and ion rejection rate according to their radii. The ion selectivity is an important factor to discover the full potential of CNT membranes, and it is affected by the functionalization of CNTs. With multivalent/size ion mixtures, the ion selectivity is affected by not only ion-functional groups interaction but also ion-ion interactions and ion size exclusion in a complex manner. In this study, molecular dynamics simulations are performed to study the ion selectivity of functionalized carbon nanotubes when multivalent/size ions are contained. The permeation energy barriers are calculated by plotting potential of mean force profiles, and various factors, such as CNT size and partial charges, affecting ion selectivity are investigated. The results presented here will be useful for designing CNT membranes for ion separation, biomimetic ion channels, etc.

Measurement and simulation of high-frequency bistatic sea surface scattering channel in shallow water of Geoje bay (거제 내만해역에서의 고주파 양상태 해수면 음파산란 채널 측정 및 모의)

  • Choi, Kang-Hoon;Kim, Yongbin;Kim, Sea-Moon;Choi, Jee Woong
    • The Journal of the Acoustical Society of Korea
    • /
    • v.40 no.1
    • /
    • pp.1-9
    • /
    • 2021
  • High-frequency bistatic sea surface scattering channels according to sea state were measured at an experimental site of Geoje bay in April 2020, and compared with predictions based on scattering theory. A linear frequency-modulated signal with a center frequency of 128 kHz and a bandwidth of 32 kHz was used for the acoustic measurements. Sea surface wavenumber spectrum was calculated from surface roughness data measured by a wave buoy, and bistatic scattering cross-section of Small Slope Approximation (SSA) based on the wavenumber spectrum was estimated. In addition, scattering from near-surface bubbles using wind speed measured during experiments was considered. Surface scattering channel intensity impulse responses were simulated using the scattering cross-section and the simulation results were compared and analyzed with the field data.

A Study on the Path Loss of Underwater Acoustic Channel Based on At-sea Experiment at the South Sea of Korea (남해 실해역 시험 기반 수중음향채널 경로손실에 관한 연구)

  • Kim, Min-Sang;Lee, Tae-Seok;Cho, Yong-Ho;Im, Tae-Ho;Ko, Hak-Lim
    • Journal of the Korea Institute of Information and Communication Engineering
    • /
    • v.24 no.3
    • /
    • pp.405-411
    • /
    • 2020
  • Recently, studies on underwater communication, related to the development of underwater resources, disaster monitoring and defense, have been actively carried out. In the design of wireless communication systems, path loss is the most important information to derive a link budget that is required to guarantee communication reliability by calculating received power level for the given communication link. The underwater acoustic channel have different characteristics according to geographical location and relevant environmental factors such as water temperature, depth, wave height, algae, and turbidity. Subsequently, many research institutes aiming to develop underwater acoustic communication systems are researching actively on the underwater acoustic channels in various sea areas. In Korea, however, studies on the path loss of the acoustic channel are still insufficient. Therefore, in this study, the path loss of the acoustic channel are studied based on measurement data of the at-sea experiment conducted at Geohae-do, southern sea of Korea.

Performance of selective combining according to channel selection decision method of frequency diversity in underwater frequency selective channel (수중 주파수 선택적 채널에서 주파수 다이버시티의 채널 선택 판정법에 따른 선택 합성법의 성능)

  • Lee, Chaehui;Jeong, Hyunsoo;Park, Kyu-Chil;Park, Jihyun
    • Journal of the Korea Institute of Information and Communication Engineering
    • /
    • v.26 no.3
    • /
    • pp.436-442
    • /
    • 2022
  • In this paper, the performance of the selective combining according to the channel selection decision method of frequency diversity is evaluated in the underwater frequency selective channel. The underwater acoustic channel in the shallow sea has a complex multipath characteristic by combining various environmental factors such as boundary surface reflection and sound wave refraction according to the water temperature layer. In particular, frequency selectivity due to multipath causes energy fluctuation in a communication channel, which reduces SNR (Signal to Noise Ratio) and deteriorates communication performance. In this paper, we applied the frequency diversity technique using multiple channels to secure the communication performance according to the frequency selectivity by multipath. For each channel, 4-FSK (Frequency Shift Keying) and selective combining were applied, the performance was evaluated by applying the maximum value, average value, and majority decision of the signal in order to decide the demodulation channel selection of the selective combining.