• Title/Summary/Keyword: Wallace

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Urgent Recanalization with Stenting for Severe Intracranial Atherosclerosis after Transient Ischemic Attack or Minor Stroke

  • Park, Tae-Sik;Choi, Beom-Jin;Lee, Tae-Hong;Song, Joon-Suk;Lee, Dong-Youl;Sung, Sang-Min
    • Journal of Korean Neurosurgical Society
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    • v.50 no.4
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    • pp.322-326
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    • 2011
  • Objective : Stenting of symptomatic intracranial stenosis has recently become an alternative treatment modality. However, urgent intracranial stenting in patients with intracranial stenosis following a transient ischemic attack (TIA) or minor stroke is open to dispute. We sought to assess the feasibility, safety, and effectiveness of urgent intracranial stenting for severe stenosis (>70%) in TIA or minor stroke patients. Methods : Between June 2009 and October 2010, stent-assisted angioplasty by using a balloon-expandable coronary stent for intracranial severe stenosis (>70%) was performed in 7 patients after TIA and 5 patients after minor stroke (14 stenotic lesions). Technical success rates, complications, angiographic findings, and clinical outcomes were retrospectively analyzed. Results : Stenting was successful in all 12 patients. The mean time from symptom onset to stenting was 2.1 days (1-8 days). Post-procedural angiography showed restoration to a normal luminal diameter in all patients. In-stent thrombosis occurred in one patient (n=1, 8.3%), and was lysed with abciximab. No device-related complications, such as perforations or dissections at the target arteries or intracranial hemorrhaging, occurred in any patient. The mortality rate was 0%. No patient had an ischemic event over the mean follow-up period of 12.5 months (range, 7-21 months), and follow-up angiography (n=7) revealed no significant in-stent restenosis (>50%). Conclusion : Urgent recanalization with stenting is feasible, safe, and effective in patients with TIA or acute minor stroke with intracranial stenosis of ${\geq}$ 70%.

Snapping Knee due to Impingement between Atypical Wrisberg Ligament and Expanded Anterior Cruciate Ligament - Report of One Case - (비전형적 리스버그인대와 비후된 전방십자인대의 충돌에 의한 탄발음 -1례 보고-)

  • Kang, Jae Do;Kim, Hyung Chun;Lee, Gi Jun
    • Journal of the Korean Arthroscopy Society
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    • v.2 no.2
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    • pp.168-172
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    • 1998
  • Discoid lateral menisci were common morphological anomaly and several classifications were proposed. Watanabe et al classified all discoid menisci, as seen arthroscopically, into three types 1) complete 2) incomplete and 3) Wrisberg ligament type. The purpose of this study is to report a rare case of both painful snapping knee joints in 6 year-old female. On arthroscopic examination, complete lateral discoid meniscus which consisted of taut Wrisberg ligament and intact tibial insertion of posterior horn was found, and abnormal anterior cruciate ligament(ACL) which has expanded femoral origin over the posterior articular surface of lateral femoral condyle was also found. At the time of arthroscopic surgery, hypertrophied high-riding Wrisberg ligament was resected, and expanded femoral origin of the anterior cruciate ligament was partially resected nearly to normal margin, and discoid lateral meniscus was saucerized. After these procedures, abnormal snapping sound was disappeared in full range of motion. On the follow-up examination after 1 year, pain and snapping sound were disappeared and any instability and limping were not found.

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CT Classification and Treatment of Intraarticular Calcaneal Fractures - Conservative vs. Surgical Treatment by Prospective Study - (관절내 종골 골절의 전산화 단층 촬영에 따른 분류 및 치료)

  • Kang, Jae-Do;Kim, Hyung-Chun;Kim, Jin-Hyung
    • Journal of Korean Foot and Ankle Society
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    • v.5 no.1
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    • pp.35-42
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    • 2001
  • Purpose: To analyze the results of conservative or surgical treatment after computed tomograhy(CT) classification in intraarticular calcaneal fractures. Materials and methods: From January 1996 to May 1999, we prospectively analyze 23 cases of intraarticular calcaneal fractures who were treated conservatively or operated by open reduction and internal fixation by extensive L-shaped lateral approach after CT classification. Results: A functional scoring system of 0-100 points which was based upon the responses to AOFAS Ankle-Hindfoot Scale for the operative group was at 82.8, compared with 73.2 for the non-operative group, and these were meaningful statistically(P<0.05). Of type I fracture, in the operative group there were 2 excellent results and in the non-operative group there were 2 excellent results, 1 good result. or type II fractures, in the operative group there were 2 excellent results, 3 good results, 1 fair result and in the non-operative group there were 1 good result, 1 fair result, 2 poor results. Of type III fractures, in the operative group there were 2 fair results, 2 poor results and in the non-operative group there were 1 fair result, 3 poor results. Bohler angles of subtalar joint were changed from initial average $13.3^{\circ}$ to postoperative average $20.9^{\circ}$ for the operative group compared with from initial average $15.5^{\circ}$ to follow-up average $14.8^{\circ}$ of the non-operative group(P<0.01). Conclusions: Computed tomography in the evaluation of intraarticular calcaneal fractures is effective tool. We believed that open reduction and internal fixation in all Crosby & Fitzgibbons type II and according to degrees of comminution reducible type III for the intraarticular calcaneal fractures is more effective method than conservative treatment.

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Acutrak Screw Fixation for Radial Head Fracture -7 Cases Report- (Acutrak 나사를 이용한 요골두 골절의 치료 -7례 보고-)

  • Kim, Kwang-Yul;Lim, Moon-Sup;Shin, Heung-Sub;Choi, Shin-Kwon
    • Journal of Korean Orthopaedic Sports Medicine
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    • v.5 no.1
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    • pp.75-80
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    • 2006
  • Purpose: To evaluate the efficiency of Acutrak screw fixation for radial head fracture (Mason type 2) without considering the safe Bone of radial head. Materials and Methods: Consecutive seven radial head fracture of Mason type II underwent internal fixation with Acutrak screws from May 2001 to February 2003. The mean follow-up period was 1.2years (ranged, $6 months{\sim}2.5 years$). The mean age of patients was 47 years old (ranged, $36{\sim}60years$ old). The cause of injury were fall down -4 cases and traffic accident -3 cases. The results were evaluated by Mayo Clinic results scoring system. Results: Functional Rating Index of Mayo Clinic was excellent- 2 cases and good- 5 cases. There were no nonunion, loosening, heterotopic ossification, infection or degenerative changes. The postoperative range of motion in elbow joint is nearly full for flexion, extension, pronation and supination in this study Conclusion: Consideration of safe zone is not necessary when Acutrak screws are used for radial head fracture. It seems to be a useful method that Acutrak screw fixation for radial head fracture (Mason type II) could achieve good radiologic and clinical results without influencing proximal radio-ulnar joint and has powerful fixation.

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Comparison of Absorption Rate Between Piroxicam-$\beta$-Cyclodextrin and Piroxicam in Korean Healthy Subjects After A Single Dose Administration (정상 성인 한국인에서 Piroxicam-$\beta$-cyclodextrin 정과 Piroxicam 확산정의 1회 투여시의 흡수속도 비교)

  • Jeon, Seong Sill;Cha, Hye Ri;Park, Yun Ju;Lee, Byung Chul;Kim, Nam Deuk
    • Korean Journal of Clinical Pharmacy
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    • v.8 no.2
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    • pp.95-100
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    • 1998
  • Piroxicam-$\beta$-cyclodextrin은 piroxicam을 $\beta$-cyclodextrin으로 포접시킨 비스테로이드성 항염증약물이다. 이러한 포접형 약물은 위장관에서의 흡수속도가 증가하는 것으로 외국자료에서 보고되고 있으며 이는 이 약물의 위장관 내성에 보다 나은 영향을 끼칠 수 있음을 시사하고 있다. 본 연구는 정상성인 한국인을 대상으로 randomized, crossover design에 의해 piroxicam-$\beta-cyclodextrin(Brexin^{(R)})$과 piroxicam 확산정$(Feldene^{(R)})$ 흡수속도를 비교하고자 하였다. 건강한 성인 8명의 피험자를 2군으로 나누어 시험약 또는 대조약을 각각 20 mg씩 20일의 휴약 기간을 두고 이중 맹검으로 교차 투여하였다. 시험약 또는 대조약의 투여 후 24시간 동안 일정 간격으로 채혈하여 HPLC 방법으로 혈장 내 piroxicam 농도를 측정하였다. $AUC_{0-24}\;({\mu}g/mL)$는 piroxicam-$\beta$-cyclodextrin군에서 $56.1\pm4.9$, piroxicam군에서 $57.3\pm5.6$으로 통계적인 유의성이 없었으나, 투여 후 0.5시간에서의 혈중농도는 piroxicam-$\beta$-cyclodextrin군 $2.9\pm0.4\;{\mu}g/mL$, piroxicam군 $1.6\pm0.3\;{\mu}g/mL$으로 통계적인 유의성을 보였다(p<0.05). 또한 최고혈중농도는 piroxicam-$\beta$-cyclodextrin$(4.3\pm0.5\;{\mu} g/mL)\;piroxicam(3.5\pm0.3\l{\mu}g/mL)$,으로 유의성이 있었으며(p<0.05), 흡수 속도상수는 piroxicam-$\beta$-cyclodextrin$(3.00\pm0.49\;h^{-1}), \;piroxicam(1.80\pm0.21\;h^{-1})$이었다(p<0.1). 이상의 결과에서, piroxicam-$\beta$-cyclodextrin정은 piroxicam 확산정과 비교하여 흡수되는 정도는 서로 비슷하지만 흡수 초기의 혈장농도 및 흡수속도상수에서 보다 빠른 약동학적 특성을 나타내었다.

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Clinical Pharmacy Research: Theory and Practice (임상약학 연구의 이론과 실제)

  • Sands Charles D.
    • 한국임상약학회:학술대회논문집
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    • 1994.11a
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    • pp.97-130
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    • 1994
  • 'The formulation of a research problem is far more often essential than its solution, which may be merely a matter of mathematical or experimental skill. To raise new questions, new possibilities, to regard old problems from a new angle requires creative imagination and marks real edvance in science.'

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Implementation of 2,048-bit RSA Based on RNS(Residue Number Systems) (RNS(Residue Number Systems) 기반의 2,048 비트 RSA 설계)

  • 권택원;최준림
    • Journal of the Institute of Electronics Engineers of Korea SD
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    • v.41 no.4
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    • pp.57-66
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    • 2004
  • This paper proposes the design of a 2,048-bit RSA based on RNS(residue number systems) Montgomery modular multiplier As the systems that RNS processes a fast parallel modular multiplication for a large word partitioned into small words, we introduce Montgomery reduction method(MRM)[1]based on Wallace tree modular multiplier and 33 RNS bases with 64-bit size for RNS Montgomery modular multiplication in this paper. Also, for fast RNS modular multiplication, a modified method based on Chinese remainder theorem(CRT)[2] is presented. We have verified 2,048-bit RSA based on RNS using Samsung 0.35${\mu}{\textrm}{m}$ technology and the 2,048-bit RSA is performed in 2.54㎳ at 100MHz.