• Transactions of the Korean Society of Mechanical Engineers B
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• v.21 no.1
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• pp.68-78
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• 1997

A numerical study on the transient vapor flow and heat transfer is performed to investigate the ideal switching operation of heat source in a high temperature heat pipe. The cylindrical 2-dimensional compressible laminar vapor flow is assumed for the vapor space and the conjugate heat transfer for the heat pipe wall, wick and vapor space is calculated. The different boundary conditions such as constant heat flux, convective or radiative boundary at the outer wall are used respectively to compare the influence of boundary conditions on the transient operation. The transient temperature profile and the internal flow of the entire pipe for the switching operation are described as a result. The results show that the transient time is not significantly affected by the boundary conditions at the outer wall in present study. During the transition, two independent flows are observed temporarily on the right side and left side of the heat pipe. It is also found that the trend of temperature variation in the vapor region is different from the variation in the wick and wall region.

• ALGAE
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• v.31 no.4
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• pp.379-390
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• 2016

When a multinucleate cell of Bryopsis plumosa was collapsed by a physical wounding, the extruded protoplasm aggregated into numerous protoplasmic masses in sea water. A polysaccharide envelope which initially covered the protoplasmic mass was peeled off when a cell membrane developed on the surface of protoplast in 12 h after the wounding. Transmission electron microscopy showed that the protoplasmic mass began to form a continuous cell membrane at 6 h after the wounding. The newly generated cell membrane repeated collapse and rebuilding process several times until cell wall developed on the surface. Golgi bodies with numerous vesicles accumulated at the peripheral region of the rebuilding cell at 24 h after the wounding when the cell wall began to develop. Several layers of cell wall with distinctive electron density developed within 48-72 h after the wounding. Proteome profile changed dramatically at each stage of cell rebuilding process. Most proteins, which were up-regulated during the early stage of cell rebuilding disappeared or reduced significantly by 24-48 h. About 70-80% of protein spots detected at 48 h after the wounding were newly appeared ones. The expression pattern of 29 representative proteins was analyzed and the internal amino acid sequences were obtained using mass spectrometry. Our results showed that a massive shift of gene expression occurs during the cell-rebuilding process of B. plumosa.

• Journal of Microbiology and Biotechnology
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• v.30 no.12
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• pp.1927-1936
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• 2020

Tunicates are known to contain biologically active materials and one species in particular, the sea peach (Halocynthia aurantium), has not been thoroughly studied. In this study we aimed to analyze the fatty acids profile of the H. aurantium body wall and its immunomodulatory effects on RAW264.7 macrophage-like cells. The fatty acids were classified into three categories: saturated fatty acids (SFAs), monounsaturated fatty acids (MUFAs), and polyunsaturated fatty acids (PUFAs). Omega-3 fatty acid content, including EPA and DHA, was higher than omega-6 fatty acids. H. aurantium body wall fatty acids exhibited enhanced immune response and anti-inflammatory effects on RAW264.7 macrophage-like cells. Under normal conditions, fatty acids significantly increase nitric oxide (NO) and PGE2 production in a dose-dependent manner, thereby improving the immune response. On the other hand, in LPS-treated RAW264.7 cells, fatty acids significantly decreased nitric oxide (NO) and PGE2 production in a dose-dependent manner, thereby enhancing anti-inflammatory effects. Fatty acids transcriptionally control the expression of the immune-associated genes, iNOS, IL-1β, IL-6, COX-2, and TNF-α, via the MAPK and NF-κB signaling cascades in RAW264.7 cells. However, in LPS-stimulated RAW264.7 cells, H. aurantium body wall fatty acids significantly inhibited expression of inflammatory cytokine; similarly, production of COX-2 and PGE2 was inhibited. The results of our present study provide insight into the immune-improving and anti-inflammatory effects of H. aurantium body wall fatty acids on macrophages. In addition, our study demonstrates that H. aurantium body wall is a potential source of immune regulatory components.

• Journal of Biomedical Engineering Research
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• v.21 no.4
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• pp.363-372
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• 2000

The present study investigated flow dynamics of a straight elastic blood vessel under sinusoidal flow conditions in order to understand influence of wall motion and impedance phase angle(time delay between pressure and flow waveforms) on wall shear stress distribution using computational fluid dynamics. For the straight elastic tube model considered in the our method of computation. The results showed that wall motion induced additional terms in the axial velocity profile and the pressure gradient. These additional terms due to wall motion reduced the amplitude of wall shear stress and also changed the mean wall shear stress. Te trend of the changes was very different depending on the impedance phase angle. As the wall shear stress increased. As the phase angle was reduced from 0$^{\circ}$to -90$^{\circ}$for ${\pm}$4% wall motion case, the mean wall shear stress decreased by 10.5% and the amplitude of wasll shear stress increased by 17.5%. Therefore, for hypertensive patients vulnerable state to atherosclerosis according to low and oscillatory shear stress theory.

• Earthquakes and Structures
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• v.8 no.5
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• pp.1255-1276
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• 2015

The importance of considering soil-structure interaction effect in the analysis and design of RC frame buildings is increasingly recognized but still not penetrated to the grass root level owing to various complexities involved. It is well established fact that the soil-structure interaction effect considerably influence the design of multi-storey buildings subjected to lateral seismic loads. The shear walls are often provided in such buildings to increase the lateral stability to resist seismic lateral loads. In the present work, the linear soil-structure analysis of a G+5 storey RC shear wall building frame resting on isolated column footings and supported by deformable soil is presented. The finite element modelling and analysis is carried out using ANSYS software under normal loads as well as under seismic loads. Various load combinations are considered as per IS-1893 (Part-1):2002. The interaction analysis is carried out with and without shear wall to investigate the effect of inclusion of shear wall on the total and differential settlements in the footings due to deformations in the soil mass. The frame and soil mass both are considered to behave in linear elastic manner. It is observed that the soil-structure interaction effect causes significant total and differential settlements in the footings. Maximum total settlement in footings occurs under vertical loads and inner footings settle more than outer footings creating a saucer shaped settlement profile of the footings. Each combination of seismic loads causes maximum differential settlement in one or more footings. Presence of shear wall decreases pulling/pushing effect of seismic forces on footings resulting in more stability to the structures.

• 한국전산유체공학회:학술대회논문집
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• 2005.10a
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• pp.49-53
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• 2005

This paper presents a multi-scale hybrid simulation for the design of a catalytic multi-tubular reactor with high performance. The multi-tubular reactor consists of shell and a large number of tubes in which various catalytic chemical reactions occur. To consider fluid dynamics in the shell-side and kinetics in the tube-side at the same time, commercial CFD package and process simulation tool are coupled. This hybrid approach allowed us to predict many kinds of meaningful results such as tube center temperature profile, heat transfer coefficients on the tube wall, temperature rise of cooling medium, pressure drop through shell and tube side, concentration profile of each chemical species along the tube, and so on., and to achieve the optimal reactor design.

• Journal of Korea Technical Association of The Pulp and Paper Industry
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• v.35 no.5
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• pp.37-45
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• 2003

To investigate the influence of the design and operating parameters of the headbox on hydrodynamics, a pilot headbox system and pressure monitoring apparatus were constructed. The pilot headbox system consisted of a circulating water reservoir, centrifugal pump, distributor, turbulence generator and slice. The distributor was designed to function as a pressure attenuator. Flow rate to the headbox and MD and CD velocity profiles in the slice zone were monitored using an ultrasonic flowmeter and Pitot tubes, respectively. As the distance from the step diffusor increased, evener CD velocity profile was observed. Wall effect increased with the increase of the velocity. Flow stability in the headbox was evaluated by injecting a dye at the outlet of the distributor. Application of theoretical analysis based on CFD in designing headboxes is briefly discussed.

• International Journal of Concrete Structures and Materials
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• v.7 no.2
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• pp.135-153
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• 2013

This study investigates the direct displacement based design (DDBD) approach for different types of reinforced concrete structural systems including single moment-resisting, dual wall-frame and dual steel-braced systems. In this methodology, the displacement profile is calculated and the equivalent single degree of freedom system is then modeled considering the damping characteristics of each member. Having calculated the effective period and secant stiffness of the structure, the base shear is obtained, based on which the design process can be carried out. For each system three frames are designed using DDBD approach. The frames are then analyzed using nonlinear time-history analysis with 7 earthquake accelerograms and the damage index is investigated through lateral drift profile of the models. Results of the analyses and comparison of the nonlinear time-history analysis results indicate efficiency of the DDBD approach for different reinforced concrete structural systems.

• Proceedings of the KSME Conference
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• 2000.11a
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• pp.452-457
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• 2000

The object of this study is to develop a reliable FEM simulation technique for the analysis of can making process using PAM-STAMP software. The processes consist of doming and necking in addition to drawing, redrawing. After body making process, this study analyzed the stability for internal pressure by simulating buckling test. Through these technique, we estimated the dome reversal pressure of steel D&I Can for various can profile and process conditions. From this study, we found the cause and mechanism of wrinkling during necking process. This mechanism is largely affected by can wall thickness and the clearance between knock out punch and necking die. The dome reversal pressure improves with increasing dome depth. These results validate the usefulness of the developed simulation technique for the analysis of body making process and optimization of the dome profile.

• Journal of the Society of Naval Architects of Korea
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• v.41 no.2
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• pp.61-69
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• 2004

In this study, flow around rudder is analyzed by utilizing the numerical calculation, and the rudder open water test is performed to validate the calculation. The aim of this study is to design the new rudder shape to improve manoeuvring performance. In first, flow around two-dimensional rudder section is analyzed to understand the characteristics of section profile. And the calculation for all-movable rudders is performed and compared with results of rudder open water test. It is hard to numerically predict the drag force because the value is sensitive to the turbulence modeling and grid spacing near the wall. However, the lift force is predicted well. And we can prove that concave profile of the rudder section produce more lift and torque than convex one as a experiment. However PANEL method that ignore viscous effect cannot distinguish the difference of them. So, we can look for the numerical tool to be developed the new rudder shape.