• The Journal of Pediatrics of Korean Medicine
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• v.27 no.4
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• pp.87-98
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• 2013

Objectives The purpose of this study is to find a literature study of infantile anorexia clinical cases with Traditional Chinese Medicine (TCM) to utilize with Korean medicine treatment methods. Methods 5 TCM journals with the highest impact factors were searched and selected among the journals listed in www.cnki.net. The search keywords were, "Children's Anorexia", "Infantile Apositia", "Infantile Anorexia", "Anorexia Nervosa", and "child of anorexia". he search was limited to the publication date from 2000 to 2012. Results Total 20 studies were selected: Acupuncture (5), Herbal medicine (9), Complex Treatment (3), External Application (2) and Moxibustion (1). Among the Acupuncture related studies, 1 study tested the effect of Sifeng (EX-UE10, 四縫), 3 studies tested the effect of Sifeng (EX-UE10, 四縫) and other acupoints treatment together, and 1 study tested the effect of combination of other acupoints. In all these studies, the study groups showed better therapeutic effects compared to the control groups. The Herbal medicine related studies showed the improvement in appetite and weight as a result of Herbal Medicines treatment. Among the Complex Treatment related studies, 2 studies tested the effect of Acupuncture and Chiropractic co-treatment, 1 study tested the effect of Moxibustion and Herbal medicine co-treatment. In all these studies, symptoms of Infantile anorexia showed significantly improved. Other papers related to External Application and Moxibustion treatment were reported improving in appetite and had other the clinical effects as well. Conclusions Clinical studies testing the effect of TCM for the treatment of Infantile Anorexia have been conducted in small scales, and all the studies showed a certain level of symptom improvement of the patients in the study groups. These results implicate that the methods in Korean medicine can be highly potential treatment options for the treatment of Infantile Anorexia. Accurate and well-controlled studies in large scale would be required to prove the effect of Korean medicine for the treatment of patients with Infantile Anorexia.

• Journal of KIISE:Computer Systems and Theory
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• v.29 no.5
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• pp.265-273
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• 2002

With the explosive growth of WWW traffic, there is an increasing demand for the high performance Web servers to provide a stable Web service to users. The cluster-based Web server is a solution to core with the heavy access from users, easily scaling the server according to the loads. In the cluster-based Web sewer, a back-end node may not be able to serve some HTTP requests directly because it does not have the requested contents in its main memory. In this case, the back-end node has to retrieve the requested contents from its local disk or other back-end nodes in the cluster. To reduce service latency, we introduce a new prefetch scheme. The back-end nodes predict the next HTTP requests and prefetch the contents of predicted requests before the next requests arrive. We develop three prefetch algorithms bated on some useful information gathered from many clients'HTTP requests. Through trace-driven simulation, the service latency of the prefetch scheme is reduced by 10 ~ 25% as compared with no prefetch scheme. Among the proposed prefetch algorithms, Time and Access Probability-based Prefetch (TAP2) algorithm, which uses the access probability and the inter-reference time of Web object, shows the best performance.

• Journal of KIISE:Information Networking
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• v.28 no.4
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• pp.463-476
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• 2001

To support the mobility, mobile computers are generally equipped with lower capability than desktop PCs or workstations in terms of the size of a display, the processing power of CPU and so on. This may give a rise to limitation in mobile computers of supporting multimedia services such as World Wide Web which users would otherwise fully enjoy in desktop PCs. Approaches to reducing the limitations are distillating original multimedia data or converting them to text. Conventional proxy servers for mobile computer simply send distillated image files with the fixed size regardless of the display size of a target mobile computer. Since the cached data is kept separately for each user, they cannot be shared among users with the same display configuration and thus the proxy server could be overloaded. In this paper, we first classify various mobile computers based on their display capability in terms of display sizes and colors. We propose an enhanced proxy server called Class-based proxy that provides a mobile computer with distillated image files in proportion to its class display capacity. The proposed proxy server allows a mobile computer user to have a homepage view similar to that in PC or Workstation. Mobile computers with the same class share the cached image files, which are distillated appropriately for that class. This helps the proxy server to get higher cache hit ratio with improved efficiency and scalability.

• Journal of the Korean Society for information Management
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• v.24 no.2
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• pp.161-179
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• 2007

As increasingly diverse kinds of information materials are available on the Internet, it becomes a challenge to define an adequate level of metadata provision for each different type of material in the context of digital libraries. This study explores issues of metadata provision for a particular type of material, statistical tables. Statistical data always involves numbers and numeric values which should be interpreted with an understanding of underlying concepts and constructs. Because of the unique data characteristics, metadata in the statistical domain is essential not only for finding and discovering relevant data, but also for understanding and using the data found. However, in statistical metadata research, more emphasis has been put on the question of what metadata is necessary for processing the data and less on what metadata should be presented to users. In this study, a case study was conducted to gauge the status of metadata provision for statistical tables on the Internet. The websites of two federal statistical agencies in the United States were selected and a content analysis method was used for that purpose. The result showing insufficient and inconsistent provision of metadata demonstrate the need for more discussions on statistical metadata from the ordinary web users' perspective.

• The KIPS Transactions:PartD
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• v.11D no.5
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• pp.1049-1062
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• 2004

With the popularization of a World Wide Web (WWW), the quantity of web information has been increased. Therefore, an efficient searching system is needed to offer the exact result of diverse Information to user. Due to this reason, it is important to extract and analysis of user requirements in the distributed information environment. The conventional searching method used the only keyword for the web searching. However, the searching method proposed in this paper adds the context information of keyword for the effective searching. In addition, this searching method extracts keywords by the new keyword extraction method proposed in this paper and it executes the web searching based on a keyword mining profile generated by the extracted keywords. Unlike the conventional searching method which searched for information by a representative word, this searching method proposed in this paper is much more efficient and exact. This is because this searching method proposed in this paper is searched by the example based query included content information as well as a representative word. Moreover, this searching method makes a domain keyword list in order to perform search quietly. The domain keyword is a representative word of a special domain. The performance of the proposed algorithm is analyzed by a series of experiments to identify its various characteristic.

• Journal of Korean Medicine for Obesity Research
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• v.9 no.1
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• pp.15-22
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• 2009

Objectives The aim of this study is to review and analyze the status on the recent clinical trials of 'obesity' and 'metabolic syndrome'. Methods We search 'www.clinicaltrail.gov' for research trend of Obesity and metabolic syndrome. Search terms used were 'obesity' and 'metabolic syndrome'. In order to see detail review, searching was performed from 01, 01, 2007 to 05, 31, 2009 with intervention, phase III or phase IV, And we classified all the searched studies into design, intervention, purpose, end point, diseases and condition Results We could search total 232 trials. Of them, we found 32 trials with intervention, phase III or phase IV from 01, 01, 2007 to 05, 31, 2009 Also we could see various design of clinical trials. Conclusion To improve obesity and metabolic study in Traditional Korean Medicine, it is need to activate clinical trial, meta analysis, develope of clinical practice guidelines, co-works with conventional medicine and etc.

• Proceedings of the Plant Resources Society of Korea Conference
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• 2018.10a
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• pp.44-44
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• 2018

경상북도 봉화군에 위치한 각화산(1,177m)은 태백산맥에서 소백산맥으로 갈라지는 기점을 이루는 산으로 구령산, 청옥산, 옥석산 등과 함께 백두대간 일대의 중요한 산으로 인식된다. 특히 각화산은 조선왕조실록을 보관했던 태백산 사고지터(사적 제 348호)를 품고 있는 역사적인 장소이기도 하다. 본 연구는 각화산 일대 관속식물의 분포상을 파악하고자 2017년 5월부터 2018년 9월까지 진행되었다. 연구 결과 조사지 내 관속식물은 92과 291속 413종 4아종 38변종 6품종으로 총 461분류군이 확인되었다. 이는 경상북도 관속식물 1,684분류군(Korea National Arboretum, 2016)의 27.4%, 한반도 관속식물 4,499분류군(Korea National Arboretum, 2018; Http://www.nature.go.kr/kpni/)의 10.2%에 해당되는 것으로 분석되었다. 각화산 일대의 주요 식물 가운데 한국특산식물은 12분류군(할미밀망, 진범, 처녀치마, 지리대사초 등)이 확인되었고, 산림청 지정 희귀식물은 VU등급(꼬리진달래, 노랑무늬붓꽃) 2분류군, LC등급(너도바람꽃, 쥐방울덩굴, 도깨비부채) 3분류군으로 총 5분류군의 희귀식물이 분포하는 것으로 조사되었다. 또한, 식물구계학적 특정식물 IV등급 5분류군, III등급 13분류군, II등급 21분류군, I 등급 25분류군이 확인되었고, 외래식물은 총 24분류군으로 도시화지수(%) 6.8%, 귀화율은 5.2%에 해당되는 것으로 분석되었다. 조사된 식물의 유용성 분석 결과, 식용식물 348분류군(75.5%), 섬유용식물 1분류군(0.2%), 약용식물 기분류군(15.4%), 관상용식물 18분류군(3.9%), 목초용식물 102분류군(22.1%) 목재용식물 14분류군(3.0%) 등으로 확인되었다. 본 연구 결과물은 각화산의 식물 현황을 제시함과 동시에 생태축으로 연결된 백두대간 일대의 효율적인 관리 및 보전 방안을 마련하기 위한 기초자료로 활용 될 것이라 기대한다.

• Proceedings of the Plant Resources Society of Korea Conference
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• 2018.10a
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• pp.45-45
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• 2018

경상북도 봉화군에 위치한 갈방산(712m)은 백두대간 옥석산(1,244m)에서 분기한 문수지맥의 산지 가운데 하나다. 본 연구는 갈방산 일대 관속식물의 분포상을 파악하고자 2017년 5월부터 2018년 9월까지 진행되었다. 연구 결과 92과 265속 373종 4아종 44변종 5품종으로 총 426분류군의 관속식물이 조사지에서 확인되었다. 이는 경상북도 관속식물 1,684분류군(Korea National Arboretum, 2016)의 25.3%, 한반도 관속식물 4,499분류군(Korea National Arboretum, 2018; Http://www.nature.go.kr/kpni/)의 9.5%에 해당되는 것으로 분석되었다. 갈방산 일대의 주요 식물 가운데 한국특산식물은 11분류군(키버들, 병꽃나무, 처녀치마 등)이 확인되었고, 산림청 지정 희귀식물은 VU등급(세잎승마) 1분류군, LC등급(도깨비부채, 태백제비꽃) 2분류군으로 총 3분류군의 희귀식물이 분포하는 것으로 조사되었다. 또한, 식물구계학적 특정식물 V등급 1분류군, IV등급 2분류군, III등급 10분류군, II등급 16분류군, I 등급 23분류군이 확인되었고, 외래식물은 총 22분류군으로 도시화지수(%) 6.3%, 귀화율은 5.2%에 해당되는 것으로 분석되었다. 조사된 식물의 유용성 분석 결과, 식용식물 345분류군(81%), 섬유용식물 4분류군(0.9%), 약용식물 85분류군(20.0%), 관상용식물 18분류군(4.2%), 목초용식물 109분류군(25.6%) 목재용식물 15분류군(3.5%) 등으로 확인되었다. 요컨대 갈방산 일대의 식물 현황을 제시함으로써 본 연구 결과물이 갈방산 일대의 희귀특산식물과 유용식물의 보전 및 활용 방안을 마련하기 위한 기초자료로 활용 될 것이라 기대한다.

• Asian Pacific Journal of Cancer Prevention
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• v.17 no.8
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• pp.4003-4007
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• 2016

Long interspersed elements-1s (LINE-1s) are dispersed all over the human genome. There is evidence that hypomethylation of LINE-1s and levels of sex steroids regulate gene expression leading to cancer development. Here, we compared mRNA levels of genes containing an intragenic LINE-1 in breast cancer cells treated with various sex steroids from Gene Expression Omnibus (GEO), with the gene expression database using chi-square analysis (http://www.ncbi.nlm.nih.gov/geo). We evaluated whether sex steroids influence expression of genes containing an intragenic LINE-1. Three sex steroids at various concentrations, 1 and 10 nM estradiol (E2), 10 nM progesterone (PG) and 10 nM androgen (AN), were assessed. In breast cancer cells treated with 1 or 10 nM E2, a significant percentage of genes containing an intragenic LINE-1 were down-regulated. A highly significant percentage of E2-regulated genes containing an intragenic LINE-1 was down-regulated in cells treated with 1 nM E2 for 3 hours (p<3.70E-25; OR=1.91; 95% CI=2.16-1.69). Similarly, high percentages of PG or AN-regulated genes containing an intragenic LINE-1 wwere also down-regulated in cells treated with 10 nM PG or 10 nM AN for 16 hr (p=9.53E-06; OR=1.65; 95% CI=2.06-1.32 and p=3.81E-14; OR=2.01; 95% CI=2.42-1.67). Interestingly, a significant percentage of AN-regulated genes containing an intragenic LINE-1 was up-regulated in cells treated with 10 nM AN for 16 hr (p=4.03E-02; OR=1.40; 95% CI=1.95-1.01). These findings suggest that intragenic LINE-1s may play roles in sex steroid mediated gene expression in breast cancer cells, which could have significant implications for the development and progression of sex steroid-dependent cancers.

• International Commerce and Information Review
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• v.16 no.1
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• pp.227-245
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• 2014

It was ten yeas ago that Bolero Bill of Lading was been introduced on the base of efforts of UN and CMI to solve the crisis of Bill of Lading, but Electronic Bill of Lading is not utilized in practice owing to the problems to be settled. Bolero Bill of Lading is not in widespread use owing to absence of collaboration model between Bolero and e-Trade service providers in each nation in the early stage. In the situation that Bolero Bill of Lading is not utilized in practice, Korean Commercial Law regulates the designation of the registration authority of Electronic Bill of Lading. Therefore, the Minister of Justice designated KTNET as Registration Authority of Electronic Bill of Lading and KTNET opened the e-B/L Korea (www.eblkorea.or.kr) to provide the Electronic Bill of Lading service to domestic trade community. But there is many problems in supplying the Electronic Bill of Lading service by the e-B/L Korea in compared with Bolero Bill of Lading. These problems are related with the characteristics of designation of Registration authority of Electronic Bill of Lading. Therefore the purpose of this paper is to contribute to the activation of Electronic Bill of Lading domestically by studying the designation of Registration authority of Electronic Bill of Lading in Korea and finding the characteristics of the designation and the issues and problems regarding the characteristics.