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Effects of Herbal-Acupuncture with Inzinsammultang on the Recovery of Liver Injury in Rats (인진삼물탕(茵蔯三物湯) 약침처리(藥針處理)가 백서(白鼠)의 간손상(肝損傷) 회부(回復)에 미치는 영향(影響))

  • Choi, Sung-Hoon;Park, Hee-Soo
    • Journal of Pharmacopuncture
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    • v.2 no.1 s.2
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    • pp.111-133
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    • 1999
  • These studies were carried out to investigate the effect of Herbal-acupuncture with Inzinsammultang extract on the recovery from liver injury of rats. The liver injury of rats induced with 0.3ml/ea carbon tetrachloride. The Herbal-acupunture with Inzinsam multang extract solution inserted into corresponding focus of Kansu(BL18) in rats. In this study, SD-Rats(Sprague-Dawley) were divided into 4 groups ; Normal group (None treated group), Control-group(The group not treated after $CCI_4$-intoxication), Treated group; Example I-group(Saline-injected groups after $CCl_4$-intoxication) and Example II-group(Inzinsammultang-injected groups after $CCl_4$-intoxication). Through histological observation, Example II-group sho-ws that liver injury is weaker than Control group.(p<0.05) Biochemical assays for each serum enzyme activities of AST, ALT and LDH, levels of albumin, ${\gamma}$-GT, TG, total cholesterol were performed. The results were summarized as follows 1. AST(Aspartate aminotransferase) activity in serum significantly decreased in the Inzinsammultang-injected groups after $CCl_4$-intoxication. Inzinsammultang-injected groups after $CCl_4$-intoxication showed significantly higher AST activities, compared with the Saline-injected groups after $CCl_4$-intoxication.(p<0.05) 2. ALT(Alanine aminotransferase) activity in serum significantly decreased in the Inzinsammultang-injected groups after $CCl_4$-intoxication. The Inzinsammultang-injected groups after $CCl_4$-intoxication showed significantly higher AST activities, compared with the Saline-injected groups after $CCl_4$-intoxication(p<0.05) 3. Level of Albumin in serum significantly increased in the Inzinsarnmultang-injected groups after $CCl_4$-intoxication. 4. LDH(Lactate dehydrogenase) activities in serum significantly decreased in the Inzinsammultang-injected groups after $CCl_4$-intoxication.(p<0.05) 5. ${\gamma}$-GT(Glutamyl transferase) in serum significantly decreased in the Inzinsammultang-injected groups after $CCl_4$-intoxication(p<0.05) 6. As for the TG(Triglyceride) levels in serum, Inzinsammultang-injected groups after $CCl_4$-intoxication is no significant differences compared with the Saline-injected groups after $CCl_4$-intoxication.(p<0.05) 7. Total cholesterol in serum significantly increased in the Inzinsarnmultang-injected groups after $CCl_4$-intoxication.(p<0.05) Those results indicate that the Inzinsammultang Herbal-acupuncture have significant effects on the liver injury induced by $CCl_4$. So it is expected that the Inzinsammultang Herbal-acupuncture can be used to cure inflammations and recover the functions of damaged liver cells.

A study on the methodology for the automatic semantic web service composition problem (자동적인 시맨틱 웹 서비스 구성문제를 위한 방법론에 관한 연구)

  • Yang, Jin-Hyuk;Lee, Kang-Chan;Kim, Sung-Han;Min, Jae-Hong;Chung, In-Jeong
    • Annual Conference of KIPS
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    • 2002.11c
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    • pp.2265-2268
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    • 2002
  • 인터넷 사용자들의 기하급수적인 증가와 웹 페이지의 폭발적인 증가로 인하여 정보공유를 위한 인터넷에서 효율적으로 원하는 정보를 발견하고 이용하기에 매우 힘든 상황에 처해있다. 따라서, 이러한 문제점들을 근본적으로 해결하기 위한 노력의 일환으로 기계가 이해하고 추론할 수 있는 시맨틱 웹이 등장하였다. 시맨틱 웹과 관련된 여러 가지 기술들 중 시맨틱 웹 서비스는 사용자에게 현재의 인터넷 환경에서 제공할 수 있는 서비스보다 향상된 고품질의 서비스를 제공하는 것을 목적으로 삼고 있다. 이러한 시맨틱 웹 서비스는 웹 서비스의 발견, 실행 및 구성으로 구성된다. 본 논문에서는 시맨틱 웹 서비스를 자동화하기 위한 노력의 일환으로서 시맨틱 웹에서 웹 서비스를 구성하는 문제에 대하여 언급한다. 시맨틱 웹 서비스 구성문제는 사용자의 요구사항을 충족시키기 위하여 다양한 웹 서비스들을 조합하는 문제이다. 그러나, WSFL, X-LANG 및 BPEL4WS 그리고, DAML-S와 같은 웹 서비스 구성문제에 대한 일련의 노력들에서는 사용자 요구사항에 대한 검증이나 서비스의 품질에 대한 사항들을 확인 및 제공할 수 있는 방법들이 없다. 따라서, 본 논문에서는 시맨틱 웹 서비스 구성문제와 관련된 상기와 같은 문제점들을 해결할 수 있는 방법론을 제시한다. 본 논문에서 제시된 방법론에서는 시맨틱 웹 구성문제를 제약만족문제로 변환함으로써 제약만족문제에 있어 늘리 알려진 다양한 알고리즘들을 활용할 수 있는 장점들이 있을 뿐만 아니라 사용자들의 요구사항에 대한 검증과 서비스의 품질을 확인할 수 있는 장점들이 있다.의 위상변화에 대한 적응성을 높일 수 있도록 한다. SQL Server 2000 그리고 LSF를 이용하였다. 그리고 구현 환경과 구성요소에 대한 수행 화면을 보였다.ool)을 사용하더라도 단순 다중 쓰레드 모델보다 더 많은 수의 클라이언트를 수용할 수 있는 장점이 있다. 이러한 결과를 바탕으로 본 연구팀에서 수행중인 MoIM-Messge서버의 네트워크 모듈로 다중 쓰레드 소켓폴링 모델을 적용하였다.n rate compared with conventional face recognition algorithms. 아니라 실내에서도 발생하고 있었다. 정량한 8개 화합물 각각과 총 휘발성 유기화합물의 스피어만 상관계수는 벤젠을 제외하고는 모두 유의하였다. 이중 톨루엔과 크실렌은 총 휘발성 유기화합물과 좋은 상관성 (톨루엔 0.76, 크실렌, 0.87)을 나타내었다. 이 연구는 톨루엔과 크실렌이 총 휘발성 유기화합물의 좋은 지표를 사용될 있고, 톨루엔, 에틸벤젠, 크실렌 등 많은 휘발성 유기화합물의 발생원은 실외뿐 아니라 실내에도 있음을 나타내고 있다.>10)의 $[^{18}F]F_2$를 얻었다. 결론: $^{18}O(p,n)^{18}F$ 핵반응을 이용하여 친전자성 방사성동위원소 $[^{18}F]F_2$를 생산하였다. 표적 챔버는 알루미늄으로 제작하였으며 본 연구에서 연구된 $[^{18}F]F_2$가스는 친핵성 치환반응으로 방사성동위원소를 도입하기 어려운 다양한 방사성의 약품개발에 유용하게 이용될 수 있을 것이다.었으나

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Concentration of Arsenic in Rice Plants and Paddy Soils in the Vicinity of Abandoned Zinc Mine (폐광산 인근 논토양과 수도의 비소함량 조사)

  • Kim, Chan-Yong;Park, Man;Lee, Dong-Hoon;Choi, Choong-Lyeal;Kim, Kwang-Seop;Choi, Jung;Seo, Young-Jin
    • Applied Biological Chemistry
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    • v.45 no.3
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    • pp.152-156
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    • 2002
  • Soils near abandoned zinc mines were known to be contaminated with arsenic-rich mining by-products. To examine the potential impacts of arsenic- contaminated soils on plant growth, surface soils were subjected to sequential extraction. Results revealed that 54% and 74% total As and 74% total extractable As were bound to iron hydrous oxide, and water soluble fraction was below detection limit. Arsenic faction extracted using the Koran standard method(dissolution of metals via treatment of 1 N HCI) was strongly correlated with the Fe-bound As fraction ($r^2=0.884**$). Arsenic level in rice plant roots was the highest with a maximum value of 154.9 mg/kg, whereas it was below 0.6 mg/kg in grains. Arsenic level in rice plant roots was strongly correlated with those of Al-bound As ($r^2=0.821**$) and 1N HCI-extractable As levels ($r^2=0.801**$).

The Comparison between Shanghanlun's and Medicine of Sasang's Viewpoins of a Diarrhea (하리(下利)의 상한론적(傷寒論的) 관점(觀點)과 사상의학적(四象醫學的) 관점(觀點)의 비교(比較)·고찰(考察))

  • Kim, Jong-Ju;Kim, June-Ki;Choi, Dall-Young
    • The Journal of Dong Guk Oriental Medicine
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    • v.7 no.2
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    • pp.9-25
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    • 1999
  • The results of the pathogenesis analysis of a diarrhea of the differential diagnosis s uggested in Sanghaulun and Dongyishoushibaoyuan are as followings. 1. The various factors such as cold, asthenia and sthenia are the pathogenesis of a diarrhea. Among of them, the asthenia-cold is the main pathogenesis, and theis sho ws that the above pathogenesis could belong under the constitutional pathogenesis of Shaoyinren. 2. Dong-Mu proved that all the symptoms of Sanyinbing were the symptom of Shao yinern. The case of Shanyinbing involved by the heat-evil, however, indicates that I t is not the pathogenesis of Shaoyangren. 3. To understand the various differential diagnosis of the pathogenesis in Sanghanlu n. the study on the theoretical relation with the constitutional pathogenesis in Dong yishibaoyuan will be necessary.

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The Impact of Brightness, Polarity, and Hue Difference on Legibility and Emotional Effect of Word in Visual Display (시각디스플레이에서 단어와 배경간의 밝기, 대비부호, 색상차이에 따른 가독성 및 감성효과)

  • Jung, Hye-Heon;Cho, Kyung-Ja;Han, Kwang-Hee
    • Korean Journal of Cognitive Science
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    • v.17 no.4
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    • pp.337-356
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    • 2006
  • This research was conducted to see the impact of brightness, polarity, and hue diference on legibility and emotional effcts of the word. In the experiment 1, stimuli with three levels of brightness difference and two-typed polarity were used. The results showed that legibility, aesthetics, and preference increased with increasing brightness difference. In the experiment 2, the same stimuli if experiment 1 included four hues: red, green, blue, yellow. As a result, the effects of brightness and polarity and the interaction effect of brightness and polarity on legibility were significant. Also, the effects of brightness, polarity, and hue and the interaction effect of brightness and hue on aesthetics and preference were significant. These results showed that legibility, aesthetics, and preference increased with increasing brightness difference of word and background and positive polarity was better than negative. Aesthetics and preference rating increased according to the following order: red, blue, green, yellow. In addition, the interaction effect of brightness and polarity on legibility was because reaction time of negative polarity was longer than positive at the small brightness difference condition. The interaction effect of brightness and hue on aesthetics and preference ws because the aesthetics rating of hue at the large brightness difference condition had significant difference compared with small brightness difference. In the experiment 3, participants rated text designs and simple color stimuli with 18 emotional adjectives to see the similarity of their emotion. The conclusion was that to reflect the subjective feelings of a rotor on the text design, it would be appropriate to use the rotor on background of the text design.

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Current Studies on Browning Reaction Products and Acidic Polysaccharide in Korean Red Ginseng (홍삼에 함유된 갈변물질 및 산성다당체에 대한 연구현황)

  • Lee, Jong-Won;Do, Jae-Ho
    • Journal of Ginseng Research
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    • v.30 no.1
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    • pp.41-48
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    • 2006
  • In the browning reaction of Korean ginseng, it appears that enzymatic and non-enzymatic browning reaction occurred In initial stage of steaming fresh ginseng at low temperature, and then non-enzymatic browning reaction followed in the drying period after steaming. Browning reaction of red ginseng occurred between $60{\sim}90$ min of steaming at $100^{\circ}C$, and browning pigments of red ginseng were mostly water soluble substances. The structural characteristics of water soluble browning reaction products(WS-BRPs) isolated from Korean red ginseng were showed the presence of hydroxyl, amide carbonyl and aliphatic methane groups. From sugar analysis it was identified that L and S-1, melanoidins isolated from red ginseng, contained two kinds of sugars, glucose and xylose, and the other melanoidin S-2 contained the previous and fructose. In order to find out pertinent methods for the acceleration of browning during ginseng processing, various treatment were made on fresh ginseng with sugars, amino acids and inorganic nitrogenous compounds and the extent of browning was measured. Among sugar tested, maltose resulted in the greatest acceleration of browning followed in decreasing order by glucose and lactose, whereas pentoses, fructose, sucrose and raffinose had negligible effect. A marked browning occurred in ginseng treated with basic amino acids, while the extent of browning was not greatly increased when ginseng was treated with aliphatic amino acids, hydroxyl amino acids, or acidic amino acids. The brown color intensity gradually increased with an increase of glucose concentration far up to 0.5M. L, S-1, and S-2 were found to have an ability to donate hydrogen to DPPH, and also they had anti-oxidative activity in the experiments of hydrogen peroxide scavenging, inhibitory activity in the formation of MDA from linoleic acid, auto oxidation of ok-brain homogenates, lipid peroxidation by the enzymatic and non-enzymatic system in liver microsome fraction, and mitochondrial fraction etc. The amounts of acidic polysaccharide(AP) in red ginseng were higher than those of wild and cultured Panax quinquefolius, Panax notoginseng as well as white ginseng (Panax ginseng). In white ginseng, the AP amount is no difference in root ages or sizes, also, the AP amount of ginseng body was similar to that of rhizome, but was higher than that of leaf and epidermis. Addition of red ginseng acidic polysaccharide(RGAP) increased production of nitric oxide(NO) and tumor necrosis factor (TNF)-$\alpha$ in the rodent macrophage cultures, and treatment of RGAP in vivo stimulated tumoricidal activities of natural killer (NK) cells.

Influence of Openings on the Structural Behavior of Shear Walls with Slabs (슬래브가 있는 전단벽의 구조적 거동에 대한 개구부의 영향)

  • Choi, Youn-Cheul;Choi, Hyun-Ki;Choi, Chang-Sik
    • Journal of the Korea Concrete Institute
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    • v.20 no.1
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    • pp.3-11
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    • 2008
  • An experimental investigation was conducted with half-scale representations of the reinforced concrete shear walls with the opening subjected to cyclic loads. Specimens were half scale representations of a one-story wall in the apartment built in 1980. The area ratio of the opening section, as well as the size and critical section of coupling slabs, were decided based on results from a previous researches. The test result of WS-0.23 specimen, which has artificial damages to install the opening, the strength of the wall decreased due to the opening. It is apparent that influence of cutting reinforcing bars and decrease of effective section area lead to early first yield of the reinforcing bars before the allowable limit of drift ratio of the shear walls was reached. Therefore, proper reinforcing method is needed to prevent this. The decrease of strength of the shear walls by installation of openings shows a great deal of difference compared to previous researches. This is because flexural capacity of the slabs is working as coupling elements for the shear walls. The critical section of coupling slabs that works as coupling elements for shear walls was a little different from the results of previous researches.

Patient Radiation Exposure Dose Evaluation of Whole Spine Scanography Due to Exposure Direction (Whole Spine Scanography의 검사방향에 따른 환자 선량 평가)

  • Kim, Jung-Su;Seo, Deok-Nam;Kwon, Soon-Mu;Kim, Jung-Min
    • Journal of radiological science and technology
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    • v.38 no.1
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    • pp.1-6
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    • 2015
  • Whole spine scanography (WSS) is a radiological examination that exposes the whole body of the individual being examined to x-ray radiation. WSS is often repeated during the treatment period, which results in a much greater radiation exposure than that in routine x-ray examinations. The aims of the current study were to evaluate the patient dose of WSS using computer simulation, image magnification and angulation of phantom image using different patient position. We evaluated the effective dose(ED) of 23 consecutive patients (M : F = 13:10) who underwent WSS, based on the automatic image pasting method for multiple exposure digital radiography. The Anterior-Posterior position(AP) and Posterior-Anterior position( PA) projection EDs were evaluated based on the PC based Monte Carlo simulation. We measured spine transverse process distance and angulation using DICOM measurement. For all patient, the average ED was 0.069 mSv for AP position and 0.0361 mSv for PA position. AP position calculated double exposure then PA position. For male patient, the average ED was 0.089 mSv(AP) and 0.050 mSv(PA). For female patient, the average ED was 0.0431 mSv(AP) and 0.026 mSv(PA). The transverse process of PA spine image measured 5% higher than AP but angulation of transverse process was no significant differences. In clinical practice, just by change the patient position was conformed to reduce the ED of patient. Therefor we need to redefine of protocol for digital radiography such as WSS. whole spine scanography, effective dose, patient exposure dose, exposure direction. protocol optimization.

Applicability of Various Biomasses to Pulverized Coal Power Plants in Terms of their Grindability (다양한 바이오매스의 분쇄도 실험을 통한 미분탄 화력발전 적용가능성 연구)

  • Kang, Byeol;Lee, Yongwoon;Ryu, Changkook;Yang, Won
    • Clean Technology
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    • v.23 no.1
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    • pp.73-79
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    • 2017
  • Recently usage of biomass is increased in pulverized coal power plants for reduction of $CO_2$ emission. Many problems arise when thermal share of the biomass is increased, and milling of the biomasses is one of the most important problems due to their low grindability when existing coal pulverizer is used. Grindability of coal can be measured through the HGI (Hardgrove grindability index) equipment as a standard, but method of measuring biomass grindability has not been established yet. In this study, grinding experiment of coal and biomass was performed using a lab-scale ball mill. One type of coal (Adaro coal) and six biomasses (wood pellet (WP), empty fruit bunch (EFB), palm kernel shell (PKS), walnut shell (WS), torrefied wood chip (TBC) and torrefied wood pellet (TWP)) were used in the experiment. Particle size distributions of the fuels were measured after being milled in various pulverization times. Pulverization characteristics were evaluated by portion of particles under the diameter of $75{\mu}m$. As a result, about 70% of the TBC and TWP were observed to be pulverized to sizes of under $75{\mu}m$, which implies that they can be used as alternative biomass fuels without modification of the existing mill. Other biomass was observed to have low grindability compared with torrefied biomass. Power consumption of the mill for various fuels was measured as well, and the results show that lower power was consumed for torrefied biomasses. This result can be used for characterization of biomass as an alternative fuel for pulverized coal power plants.

Lycopene Content and Fruit Morphology of Red, Pink, Orange, and Yellow Fleshed Watermelon (Citrullus lanatus) Germplasm Collections

  • Noh, Jae-Jong;Hur, On-Sook;Ro, Na-Young;Lee, Jae-Eun;Hwang, Ae-Jin;Kim, Bit-Sam;Rhee, Ju-hee;Yi, Jung Yoon;Kim, Ji Hyun;Lee, Ho-Sun;Sung, Jung-Sook;Kim, Myung-Kon;Assefa, Awraris Derbie
    • Korean Journal of Plant Resources
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    • v.33 no.6
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    • pp.624-637
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    • 2020
  • High-quality and high-phytonutrient watermelon fruits have strong market opportunities besides their health related benefits. Hence, investigating quality and nutritional related traits of watermelon genetic resources could provide important baseline data in breeding for increased lycopene content thereby increasing the marketability of watermelon. To this end, we have examined some fruit morphological traits and lycopene content of 105 genetic resources. Seeds, originally obtained from 22+ countries, were obtained from the National Agrobiodiversity Center, Jeonju, South Korea, grown in an experimental field and harvested at a fully mature stage. The size of pistil scar (SPS), the width of stripes (WS), weight of fruit (WF), length of fruit (LF), width of fruit (WIF), the thickness of pericarp (TP), soluble solids content (SSC), fruit shape in longitudinal section, ground color of skin, the intensity of the green color of skin, fruit shape at the apical part, grooving distribution, conspicuousness of stripes, and main color of the flesh were recorded on the field and inside laboratory and the lycopene was measured using spectrophotometric and HPLC methods. Watermelon fruits have shown a diverse morphological characters. Red and pink fleshed fruits dominated in the entire collections. Fruits with higher thickness of rind were found to exhibit less soluble solid content (SSC). Korean origin fruits were characterized by intermediate SSC while the United States of America (USA), Russia (RUS), Tajikistan (TJK), Turkmenistan (TKM), Taiwan (TWN), and Uruguay (URY) originated fruits had the highest SSC. The lycopene content varied between 41.37 and 182.82 ㎍/g, 2.81 and 163.72 ㎍/g, and 3.54 and 255.47 ㎍/g using HPLC, UV-Vis spectrophotometer, and microplate reader spectrophotometer, respectively. Red- and pink-fleshed fruits had the highest levels of lycopene content compared to the yellow- and orange-fleshed. Lycopene content had a significant positive correlation with SSC, however, no correlations were detected between lycopene and other quantitative fruit morphological characters. Our study demonstrated high diversity exists in fruit morphological traits and lycopene content of the germplasm collections which provide beneficial baseline data for a future breeding program and utilization of watermelon germplasm collections in gene banks for the maintenance and improvement of the current levels of production, marketability, and health-related benefit of watermelon fruits.