• 간호행정학회지
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• 제4권1호
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• pp.151-181
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• 1998

This study purports to find out the meanings of chemotherapy among cancer patients. The subjects of this study were selected from those patients who have taken chemotherapy at least twice at a hospital affiliated with a university. The twelve subjects agreed to join the present study and had no problem in communication with others. The data were collected through observations and interviews by the researcher. The phenomenological analysis method proposed by Giorgi was adopted for analyzing the data. The experiences of the subjects to chemotherapy were classified into 24 atributes. These attributes were also categorized into four groups such as hope, pain, fear, and ordea according to their meanings. The subjects expressed hope through the attributes such as "the wish for a new life." "the wish for healing." "the plasure form improvement of cancer." "the wish for being discharged form a hospital." "the interest in dietectic treatment." and "the trust in medical staff." Pain was represented by such attributes as "the physical pain", "the suffering from intravenous injection." "the discomfort of hospital environment." and "the economic burden." As for the attributes represention fear, "fear of being hospitalized." "tehr obscurity of uncertain situations." "the fear of side effects." "the fear of recurrence of cancer," "the lack of knowledge of the disease." Finally, nine attributes werw frouped to ordeal "the will endeavouring to recover cancer" "the adaptation to the present situation." "the giving up of being healthy," "the regret of the past life." "the recognition of significant others." "the physical changes." "the emotional changes." "the social changes." "the recollection of illness experiences." The above findings indicate that chemotherapy means hope, pain, fear, and ordeal to those cancer patinests under treatment. Hence, the nursing interventions for those cancer patients need to be directed to maintaining hope, alleviating pain and fear, and overcoming ordeal. There are some suggestions in achieving these goals : (1) the nurses caring for cancer patients need to understand the meaning of chemotherapy experienced by those patients, (2) a nursing specialty of intravenous injection needs to be developed, (3) interventions for providing emotional support should be devised, (4) nursing care should also be available to those cancer patients being dischaged at home.

• Asian Pacific Journal of Cancer Prevention
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• 제16권14호
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• pp.5635-5641
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• 2015

Background: Cirrhosis is regarded as a possible end stage of many liver diseases, including viral infection. It occurs when healthy liver tissue becomes damaged and is replaced by scar tissue and finally may lead to hepatocellular carcinoma. Interferons (IFNs)are two general categories, type I and II. Type I includes one beta interferon and over 20 different alpha interferons. Alpha interferons are very similar in how they work, interacting with other proteins on cells like receptors. The main objective of this study was to compare Mx gene productivity post different cell line treatment with imported and Egyptian biosimilar locally produced IFNs, as well as the efficacy of those tested IFNs. Also, an assessment was made of sensitivity of different cell lines as alternatives to that recommended for evaluation of antiviral activity. Materials and Methods: Different cell lines (Vero, MDBK and Wish) were employed to evaluate cytotoxicity using the MTT assay. Antiviral activity was evaluated compared with standard IFN against VSV, Indiana strain -156, on tested rh-IFNs (imported; innovated and Egyptian biosimilar locally produced IFNs) in the pre-treated cell lines previously mentioned. The virus was propagated in the Wish cell line as recommended. Finally we estimated up-regulation of the Mx gene as a biomarker. Results: Data recorded revealed that test IFNs were safe in test cell lines. Viability was around 100%. Locally tested interferon did not realize the international potency limits, while the imported one was accepted compared with the standard IFN. These results were the same either using infectivity titer reduction assay or crystal violet staining of residual non- infected cells. Mx protein production was cell type related and confirmed by the detected Mx gene expressed in imported and locally produced IFN pre-treated cell lines. The expression of the gene was arranged in the order of Vero> wish > MDBK for the imported IFN, while for the Egyptian biosimillar locally produced one it was MDBK> Vero> wish. With regard to the antiviral activity there was a significant difference of imported IFN potency compared with the locally produced IFN (P<0.05), the IFN potential (antiviral activity) was not cell line related and showed non-significant difference for each separate product. Conclusions: Vero cells can be used as an alternative cell line for evaluation of IFN potency in case of unavailable USP recommended cell lines. Alternative potency evaluation assay could be used and proved significant difference in IFN potency in case of local and imported agents. Evaluation of antiviral activity could be used in parallel to viral infectivity reduction assay for better accuracy. Mx gene can be used as a marker for IFN potential.

• Kyungpook Mathematical Journal
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• 제27권2호
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• pp.145-152
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• 1987

In this paper we wish to establish some new integral in equalities of the Gronwall-Bellman-Reid type that have a wide range of applications in the differential and integral equations.

• 대한약학회:학술대회논문집
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• 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.1
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• pp.90-90
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• 2003

Sample size calculations play an important role in bioequivalence trials. In almost all clinical trials sample size is determined by considering power under the alternative hypothesis. The alternative hypothesis is the hypothesis that we wish to prove with experiments. Hence, in bioequivalence trials the alternative hypothesis is that two formulations are bioequivalent, while the null hypothesis is that the two formulations are not bioequivalent. (omitted)

• 한국철도학회:학술대회논문집
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• 한국철도학회 2004년도 춘계학술대회 논문집
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• pp.613-618
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• 2004

Is confirming safety of derailment when wish to develop new vehicles or upgrade running speed of vehicles. This means the measure of wheel load and lateral force that act between wheel and rail. So far, problem in continuous measuring method of derailment coefficient was sensitivity decline and noise growth. This research supplemented these problems by composition of new bridge circuit.

• 호남수학학술지
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• 제1권1호
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• pp.77-81
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• 1979

Almost mathematicians wish to study on the classification of the objects within isomorphism and determination of effective and computable invariants to distinguish the isomorphism classes. In topology, the concepts of homotopy and homeomorphism are such examples. In this lecture I shall speak of with respect to (i) Thom's cobordism group (ii) Cobordism category (iii) finally, the semigroup in cobordism category is isomorphic to the Thom's cobordism group.

• 대한수학회논문집
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• 제34권3호
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• pp.799-809
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• 2019

In this note our aim is to extend the Huygens type inequalities to the Bessel and modified Bessel functions of the first kind. Our main motivation to write this note is a recent publication of Zhu, which we wish to complement.

• Asian Pacific Journal of Cancer Prevention
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• 제13권9호
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• pp.4267-4272
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• 2012

Purpose: The aim of this study was to identify the opinions of Turkish adolesecent girls and their parents about HPV vaccination and the consistency. Methods: This descriptive study covered 301 girls and their parents. Questionnares were developed by the researchers based on findings within the literature and applied for data collection. Results: The mean age was 19.4 for girls, 44.2 for mothers and 47.9 for fathers. It was found that 43.5 percent of girls and 31.9 percent of mothers wish to be vaccinated against HPV. Also, 45.5 percent of mothers and 44.9 percent of fathers wish for their daughters to be vaccinated against HPV. A moderate consistency was found between mothers and fathers; a low consistency was found between fathers and girls, and between mothers and girls. Conclusions: The study indicates that an appropriate background has been partially provided about the acceptability of the vaccine between parents and their daughters in Turkey. However, the vast majority of adolescent girls and parents are indecisive or reluctant about HPV vaccination. This study also showed that the decisions of adolescents about vaccination may be affected by the opinions of the parents.

• 한국콘텐츠학회:학술대회논문집
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• 한국콘텐츠학회 2006년도 추계 종합학술대회 논문집
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• pp.849-852
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• 2006

본 연구에서는 전자파를 차단 및 흡수하는 물질을 개발하는 추세에 발맞추어 전자파를 흡수할 수 있는 물질을 이용하여 상품화 시키는 것에 초점을 두었다. 예컨대 휴대폰에서 전자파가 많이 발생하게 되는데 전자파를 흡수할 수 있는 물질을 이용하여 만든 캐릭터를 핸드폰 밧테리 부분에 부착 사용하여 전자파를 차단하고자 하는 것이다. 이때 차단하는 부위를 전자파 차단이란 본래 기능외에 캐릭터 개념을 도입하여 악세사리 겸용으로 부착하여 사용할 수 있는 캐릭터를 연구하고자 한다. 캐릭터디자인은 소비자설문조사를 실시하여 선호도가 가장 높은 것을 적용 반영하여 마무리하였다.

• 한국언어정보학회지:언어와정보
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• 제18권1호
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• pp.1-32
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• 2014

This paper provides a corpus study on subjunctives in Korean in a way of comparative semantics. The whole arguments of this paper are bolstered by distributional evidence taken from naturally occurring bitexts (i.e. a bilingual corpus), in which one sentence in a language is aligned with one translation in the other language. Since previous studies regard past tense morphology as the main component to express irrealis and uncertainty, this paper accordingly checks out whether the past tense morpheme (e/a)ss in Korean is also responsible for conveying the meaning of subjunctives. My finding is that the past tense morpheme (e/a)ss is a sufficient condition for forming subjunctives in Korean. The current corpus study verifies that the past tense morpheme is not obligatorily used in present conditional counterfactuals in Korean, unlike English. Yet, if (e/a)ss is used and the antecedent denotes a present situation, the conditional sentence can only be interpreted as conveying counterfactuality. On the other hand, wish constructions in Korean, irrespective of the semantic tense, often contain the past tense morpheme. Hence, this work substantiates Iatridou (2000)'s theory of 'fake past tense' is applicable to Korean subjunctives. The present corpus study, additionally, reveals that a conditional marker telamyen is a component of expressing past counterfactuals in Korean.