• Korean Journal of Clinical Pharmacy
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• v.21 no.2
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• pp.74-80
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• 2011

Population pharmacokinetics for gentamicin were compared with 20 Korean patients (14 male and 6 female) and 25 Caucasian appendicitis patients (16 male and 9 female). Two to six blood specimens were collected from all patients at the following times : just before a regularly scheduled infusion and at 0.5 hour after the end of a 0.5 hour infusion. Nonparametric expected maximum(NPEM) algorithm for population modeling was used. The estimated parameters were the elimination rate constant(K), the slope(KS) of the relationship between K versus creatinine clearance(Ccr), the apparent volume of distribution (V), the slope(VS) of the relationship between V versus weight, gentamicin clearance(CL) and the slope(CS) of the relationship between CL versus Ccr and the V. The output includes two marginal probability density function(PDF), means, medians, modes, variance, skewness, kurtosis, and CV%. The mean K(KS) were$0.402{\pm}0.129hr^{-1}$ ($0.00486{\pm}0.00197[hr{\cdot}mL/min/1.73m^2]^{-1}$) and $0.425{\pm}0.137hr^{-1}$($0.00432{\pm}0.00168[hr{\cdot}mL/min/1.73m^2]^{-1}$) for Korean and Caucasian populations, respectively. The mean V(VS) were not different at $14.3{\pm}3.69L$($0.241{\pm}0.0511L/kg$) and $15.8{\pm}4.81L$($0.236{\pm}0.0531L/kg$) for Korean and Caucasian populations, respectively (P>0.2). The mean CL(CS) were $5.68{\pm}1.69L/hr$ ($0.0714{\pm}0.0222L/kg[hr{\cdot}mL/min/1.73m^2]$) and $6.29{\pm}1.84L/hr$ ($0.0629{\pm}0.0189L/kg[hr{\cdot}mL/min/1.73m^2]$) for Korean and Caucasian populations, respectively. There are no differences in gentamicin pharmacokinetics between Korean and Caucasian appendicitis patients.

• Journal of the Korea Institute of Information Security & Cryptology
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• v.28 no.2
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• pp.429-436
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• 2018

Electronic documents are efficient to be created and managed, but they are liable to lose their originality because copies are created during distribution and delivery. For this reason, various security technologies for electronic documents have been applied. However, most security technologies currently used are for document management such as file access privilege control, file version and history management, and therefore can not be used in environments where authenticity is absolutely required, such as confidential documents. In this paper, we propose a method to detect document forgery and tampering through analysis of file system without installing an agent inside the instance operating system in cloud computing environment. BubbleDoc monitors the minimum amount of virtual volume storage in an instance, so it can efficiently detect forgery and tampering of documents. Experimental results show that the proposed technique has 0.16% disk read operation overhead when it is set to 1,000ms cycle for monitoring for document falsification and modulation detection.

• 한국신재생에너지학회:학술대회논문집
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• 2009.06a
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• pp.286-286
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• 2009

A small PEM fuel cell has two different stack configurations such as active and passive stacks. The active stack has a distintion of high power density although it makes system complex by using alr blower and related BOPs resulting in large system volume. On the contrary, passive stack has an advantage of compact system because it doesn't need air supplying devices although it reveals relatively low stack power density. In this study we fabricated two 10W PEMFC stacks with different stack configurations, active and passive stacks, and tested their performance and stability. The active stack consists of 13cells with an active area of $5cm^2$. The passive stack has 12cells with an active area of $16cm^2$. When we compared the stack performance of those stacks, the active stack showed higher power density compared to the passive stack, particularly at high voltage regions. However, at low voltage and high current regions, the passive stack performance was comparable to the active stack. The stack stability was largely dependent on the fuel humidity, particularly for active stack. At low humidity conditions, the active stack performance was decreased continuously and the cell voltage distribution was not uniform showing seriously low cell voltage at center cells mainly due to the cell drying. The passive stack showed relatively stable behavior at low humidity and the stack performance was largely dependent on the atmospheric conditions.

• Biomedical Science Letters
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• v.13 no.1
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• pp.11-15
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• 2007

We examined the effects of pregnancy and pregnancy-induced hypertension (PIH) on platelet activation. Thirty-six women with PIH (blood pressure > 140/90 mm Hg after two consecutive measurements after the $24^{th}$ weeks of gestation) without proteinuria, fifty-six normotensive pregnant women, and fifty non-pregnant women were studied. WBC, RBC, platelet related variables, including mean platelet component (MPC), mean platelet volume (MPV) and platelet component distribution width (PCDW) were determined for this study. MPC levels were significantly lower in women with PIH compared with normotensive pregnant women and non-pregnant women (P<0.05). MPC levels were inversely con-elated with PIH (r=-0.49, P<0.001), systolic BP (r=-0.22, P<0.01), diastolic BP (r=-0.17, P<0.005), WBC (r=-0.30, P<0.001), MPV (r=-0.41, P<0.001), and PCDW (r=-0.68, P<0.001), and positively con-elated with RBC (r=0.32, P<0.001), platelet count (r=0.21, P<0.05), and mean platelet mass (MPM) (r=0.18, P<0.05). MPC levels were found to be an independent factor associated with PIH and PCDW (P<0.01) after adjustments were made for potential confounding factors such as gestational age, systolic blood pressure, diastolic blood pressure, WBC, RBC, Platelet count, and PCDW. In conclusion, MPC levels were significantly lower in women with PIH, and MPC levels were found to be an independent factor associated with PIH and PCDW. Therefore, platelet activation is suggested as a useful predictor for patients with PIH.

• Journal of the Korean Society for Aeronautical & Space Sciences
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• v.42 no.6
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• pp.515-521
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• 2014

In this paper, we designed axis-displaced Gregorian antenna by using Ray-tracing method. This antenna improves gain, VSWR by rotating the axis of the sub-reflector to get rid of E-field wave returned from sub-reflector to feed horn. Therefore it reduce the sub-reflector size and the volume of antenna. This method is used to track the propagation path for radiation pattern of feed horn from feed horn to sub-reflector, main-reflector and air. We get E-field distribution of this antenna aperture and calculate antenna radiation pattern and optimize the antenna performance. The Ray-tracing Method was verified because the gain, radiation patterns, side lobe level, beam width and return loss of the designed antenna are very similar to CST simulation result and a measured result of the fabricated antenna.

• Composites Research
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• v.12 no.1
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• pp.68-75
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• 1999

This study has observed that the dynamic behavior of Metal Matrix Composites (MMCs) in low velocity impact varies with impact velocity. MMCs with 15 fiber volume percent were fabricated by using the squeeze casting method. The AC8A was used as the matrix, and the alumina and the carbon were used as reinforcements. The tensile and vibration tests conducted yielded the yielded the tensile stress and elastic modulus of MMCs The low pass filter and instrumented impact test machine was adopted to study dynamic behaviors of MMCs corresponding to impact velocity. Stable impact signals were obtained by using the low pass filter. Impact corresponding to impact velocity. Stable impact signals were obtained by using the low pass filter. Impact energy of unreinforced alloy and MM s increased as the impact velocity increased. The increase of crack propagation energy was especially prominent, but the dynamic toughness of each material did not change much. To show the relation between crack initiation energy and dynamic fracture toughness, a simple model was proposed by using the strain energy and stress distribution at notch. The model revealed that crack initiation energy is proportional to the square of dynamic fracture toughness and inversely proportional to elastic modulus.

• Journal of the Korean Geophysical Society
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• v.8 no.2
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• pp.89-92
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• 2005

For the understanding the locus of the Quinling-Dabie-Sulu continental collision’s boundary and the underground structure of the sedimentray basin in the Yellow Sea, three dimensional density modelling is carrid out by using gravity dataset (Free Air Anomaly), which is measured by Tamhae 2, GIGAM in a period 2000-2002. The measured gravity anomaly in the investigations area is mainly responsed by depth distribution of the sedimentary basin. After comparing the sea-measured gravity data to CHAMP-GRACE satellite gravity data, I suggested that the high density model bodies extend mainly from the southern part of China to the middle-western part of the Korean Peninsula, which might be emplaced along the continental collision’s boundary. The total volume of very low density bodies modified by modelling might be about 20 000 km3.

• Journal of Convergence for Information Technology
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• v.12 no.4
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• pp.270-277
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• 2022

Today, due to the serviceization of the economy, volume and position Global trade in Services have gradually increased. Stable and fair trade can be achieved through solid international trade law. Multilateral discussions on service trade agreement have been stagnant, but have recently shown considerable outcome. Service trade agreement(GATS) deal with various service trade barriers in member countries that hinder free trade in services. Recently, a group of WTO members have established the 「Joint Initiative on Services Domestic Regulation」. The agreement aims to ensure that licensing and qualification requirements and procedures, as well as technical standards do not constitute unnecessary barriers to services trade. This study is to understand the type and statistics of service trade barriers that affect actual service transactions. At the same time, It aims to examine the progress of discussions on multilateral service trade agreement for resolving service trade barriers.

• Composites Research
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• v.13 no.3
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• pp.9-20
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• 2000

Free vibration characteristics of a cantilevered laminated composite beam with multiple non-propagating transverse open cracks are investigated. In the present analysis a special ply-angle distribution referred to as asymmetric stiffness configuration inducing the elastic coupling between chord-wise bending and extension is considered. The multiple open cracks are modelled as equivalent rotational springs whose spring constants are calculated based on the fracture mechanics of composite material structures. Governing equations of a composite beam with open cracks are derived via Hamilton's Principle and Timoshenko beam theory encompassing transverse shear and rotary inertia effect is adopted. The effects of various parameters such as the ply angle, fiber volume fraction, crack numbers, crack positions and crack depthes on the free vibration characteristics of the beam with multiple cracks are highlighted. The numerical results show that the existence of the multiple cracks in an anisotropic composite beam affects the free vibration characteristics in a more complex fashion compared with the beam with a single crack.

• Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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• v.29 no.2
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• pp.209-217
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• 2011

This study incorporate hydroacoustic sampling for bathymetry and sediment survey in Won Cheon reservoir, Suwon city, Korea. Bathymetric and sedimentation surveys were conducted using a echo sounder system and subbottom profiler in the reservoirs. Data were collected using echo sounder systems and subbottom profiler linked to a GPS, to maximize data accuracy and vessel use, and geo-referenced using a DGPS enabling the acoustic data to be used in a GIS. Echo sounder and subbottom survey data were merged within geographic information system(GIS) software to provide detailed visualization and analyses of current depths, pre-impoundment topography, distribution, thickness, and volume estimates of lacustrine sediment, and water storage capacity. These data and analyses are, necessary for development of long term management plans for these reservoirs and their watersheds.