• Proceedings of the Korea Water Resources Association Conference
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• 2022.05a
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• pp.245-245
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• 2022

최근 국내 기후변화에 따른 국지성 집중호우로 인한 시간당 강우량의 증가로 도로부 유출량의 증가와 배수관거에서의 내수배제 불량에 따른 도심지 내수침수 피해가 증가함에 따라 이를 해결하기 위한 우수유출저감시설이 설치되고 있다. 그러나 대단위의 지하 저류시설의 지속적인 설치는 과밀화된 도심지에서 설치 지하공간의 구조적인 한계 및 적정 설치 위치의 미확보 등의 다양한 문제가 발생하여 저류시설의 침수저감 효과에 대한 추가적이고 새로운 저류시설에 대한 연구가 필요한 실정이다. 이에 내수 침수 저감 및 배수 능력 향상을 위한 도로 배수시설과 연계된 도로 측구부 저류시스템 구축이 필요하다. 이를 위해 역류 방지 및 노면수 저류 빗물받이에 적용되는 부력식 역류차단장치를 개발하였으며, 역류차단장치의 최적 형상 개발을 위해서 기존 빗물받이 연결관과의 통수능 비교 및 분석이 필요한 실정이다. 따라서 본 연구에서는 기존 빗물받이 연결관 및 연결관 내에 역류차단장치가 적용된 역류차단 빗물받이의 흐름분석을 위해 Fluent 모형을 이용하여 3차원 수치모의를 수행하였다. 수치모의 구성으로는 전체 형상을 40×50cm의 빗물받이 유입부와 50×50cm의 빗물받이로 결정하고 격자는 빗물받이 내부의 복잡한 3차원 흐름을 모의하기 위해 1.2~2mm 크기로 생성하였다. 다상유동 해석을 위해 VOF(Volume of Fluid)방법을 적용하였고, 수치해석 방법으로는 비정상류, 난류 모형으로는 SST k-𝜔모형을 적용하였다. 해석조건으로는 김정수(2021) 등이 제시한 4차선 기준 설계빈도별(5~30년) 빗물받이 유입유량을 산정하여 빗물받이 유입조건으로 선정하였으며, 빗물받이와 연결관에서의 통수능력 분석 조건으로는 빗물받이에 기존 연결관이 부착된 조건과 연결관 내에 역류차단장치가 설치되어 역류차단장치가 개방된 조건에서의 통수능을 비교하였으며, 역류상황을 가정한 연결관에서의 통수능을 비교하기 위하여 역류차단장치의 개폐정도를 15도(통수단면 33%감소) 닫힌 상태 및 30도(통수단면 67% 감소) 닫힌 상태 조건을 대상으로 빗물받이와 연결관에서의 흐름을 모의하였다. 수치모의 결과 역류차단장치의 계폐조건에 상관없이 5년 빈도유입량 조건에서는 완전 배수가 되었으며, 개폐조건 15도에서는 10년 빈도의 유입량에서는 완전 배수가 되었으나 20년 빈도 이상의 유입량 조건에서 빗물받이 유입부로의 역류가 발생하였으며, 개폐조건 30도에서는 5년 빈도 이상 유입량 조건에서 빗물받이 유입부로 역류가 발생하는 것으로 나타났다. 특히, 30년 빈도 이상의 유입량부터는 빗물받이 연결관 내에 역류차단장치 개페조건과 관계없이 빗물받이 유입부로의 역류로 인한 도로 침수가 발생하기 때문에 유휴공간인 도로 측구부를 저류공간으로 활용할 수 있는 도로 측구부 저류시스템의 구축은 필수적이라고 판단되며, 유량 조건에 따른 빗물받이 내부 와 흐름과 유출부에서의 유속 변화 특성을 확인하였다. 그러므로 측구 저류조 개발 형상과 연결한 3차원 흐름의 구현 및 분석에 Fluent 모형의 적용이 가능하다고 판단된다.

• Proceedings of the Korea Water Resources Association Conference
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• 2022.05a
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• pp.234-234
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• 2022

도로에서의 우수를 원활하게 처리하기 위해서 빗물받이 및 연결관 등의 노면 배수시설이 설치되고 있으며, 노면 배수는 측구부를 통해 흘러 빗물받이 유입부로 차집되고 연결관을 통해 하수관거로 배수된다. 그러나 최근 국내 기상패턴의 변화로 국지성 집중호우와 같이 시간당 강우량 증가로 도로부와 저지대에서 배수시설의 배수불량에 따른 도심지 내수침수 피해가 발생하고 있다. 이에 정부에서는 다양한 우수관거 개선사업, 빗물펌프장, 지하저류조와 같은 방재시설을 설치하고 있으나 우수유출저감시설은 대규모 예산이 소요되고 실제 침수지역에 피해 저감효과에 대한 효용성 문제에 대한 제기뿐만 아니라 과밀화된 도심지에서는 지하공간 활용에 한계가 있는 실정이므로 도심지의 다양한 공간을 활용한 도시 배수 및 저류시설에 대한 연구가 필요하다. 따라서 본 연구에서는 유휴 공간인 도로 측구부 공간을 활용하여 도로 노면수를 저류 및 지체할 수 있는 노면수 측구 저류시설의 개념을 제시하고 측구저류조의 활용성을 판단하기 위하여 빗물받이 유입구, 빗물받이, 측구 저류조 및 빗물받이와 측구저류조 연결부에서의 노면수 유입, 유출 및 저류 등의 다양한 흐름 변화를 확인하기 위하여 Fluent 모형의 적용성을 분석하였다. 수치모의 전체 형상은 50x50cm 크기의 빗물받이를 기준으로 양쪽에 2m 길이의 측구 저류조를 원형관으로 연결하여 1/5 축소모형으로 구성하고 격자는 빗물받이 유입부, 빗물받이 및 측구 저류조 내부의 복잡한 3차원 흐름을 모의하기 위해 사면체와 육면체로 조밀하게 생성하였다. 다상유동해석을 위해 VOF(Volume of Fluid)방법을 적용하였고, 수치해석 방법으로는 비정상류, 난류 모형으로는 SST k-ω모형을 적용하였다. 수치모의 조건으로는 설계빈도별(5~30년) 우수유출량을 산정하여 유입 유량별 기존 빗물받이 유입부에서의 유입흐름, 빗물받이 내부에서의 와 발생흐름, 측구 저류조 및 연결관에서의 흐름을 구현하여 분석하였다. 수치모의 결과 빗물받이 유입부에서 연결관을 통한 측구 저류조로 유입되는 유입흐름과 빗물받이 하단부의 배수관을 통해 유출되는 흐름을 정상적으로 구현하였으며, 빗물받이 유입부 및 측구 저류조 연결관에서의 유속변화도 확인할 수 있었다. 또한 빗물받이와 측구 저류조에서 다양한 흐름을 구현하기 위한 Flunet 모형의 적용성을 검토하였으며, 향후 수리실험을 통하여 실제 흐름과의 매개변수 최적화 및 다양한 도로 조건의 변화를 고려한 수치모의 분석을 통하여 지속적인 모형의 검증이 가능할 것으로 판단된다.

• Clinical and Experimental Pediatrics
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• v.50 no.7
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• pp.660-664
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• 2007

Purpose : Pleural effusion is a common complications of pediatric bacterial pneumonia. Intrapleural administration of fibrinolytic agents such as urokinase have been used in the management of complicated parapneumonic effusions. But the safety and effectiveness of intrapleural urokinase instillations in children has not been confirmed. The aim of this study is to evaluate the safety and effectiveness of intraperitoneal urokinase in children. Methods : We reviewed a total of 29 children diagnosed as parapneumonic effusion with septation by chest CT or chest ultrasonography. We divided them into two groups. Fourteen children treated with urokinase after thoracostomy (Group A) were compared with 15 children treated only with thoracostomy (Group B). The urokinase, 3,000 IU/kg/day, was injected into the pleural cavity twice a day. Results : There was no statistical difference in sex and age between the two groups. Total drainage volume during thoracostomy in group A and B was 375.5 mL and 350.0 mL, respectively. It was not statistically significant. But the amounts of pleural fluid of group A on day 1, day 2 and day 3 were 102.5 mL, 100.0 mL, and 70.0 mL respectively and those of group B on day 1, day 2 and say 3 were 120.0 mL, 50.0 mL and 15.0 mL respectively. To compare group A with group B in the amounts of drainage volume on day 1 was not statistically significant, but the amounts of drainage volumes on day 2 and day 3 in group A were statistically more significant than group B (Day 1 P=0.371, Day 2 P=0.049, Day 3 P=0.048, respectively). The duration of fever, antibiotics, thoracostomy and total hospital days. Were not statistically significant between the two groups. But the frequency of complications in Group A was statictically significantly lower than in group B. Conclusion : Intrapleural instillation of urokinase facilitates the drainage of loculated pleural effusions, especially during the first 3 days, and it could reduce complications, such as pleural thickening, surgical managements, re-positioning of tube and re-thoracostomy. So intrapleural urokinase injection was and effective and safe treatment of pleural effusion in children (P=0.014).

• Journal of Korea Water Resources Association
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• v.52 no.10
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• pp.743-752
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• 2019

The flow in the meandering channel is characterized by the spiral motion of secondary currents that typically cause the erosion along the outer bank. Hydraulic structures, such as spur dike and groyne, are commonly installed on the channel bottom near the outer bank to mitigate the strength of secondary currents. This study is to investigate the effects of submerged vanes installed in a $90^{\circ}$ meandering channel on the development of secondary currents through three-dimensional numerical modeling using the hybrid RANS/LES method for turbulence and the volume of fluid method, based on OpenFOAM open source toolbox, for capturing the free surface at the Froude number of 0.43. We employ the second-order-accurate finite volume methods in the space and time for the numerical modeling and compare numerical results with experimental measurements for evaluating the numerical predictions. Numerical results show that the present simulations well reproduce the experimental measurements, in terms of the time-averaged streamwise velocity and secondary velocity vector fields in the bend with submerged vanes. The computed flow fields reveal that the streamwise velocity near the bed along the outer bank at the end section of bend dramatically decrease by one third of mean velocity after the installation of vanes, which support that submerged vanes mitigate the strength of primary secondary flow and are helpful for the channel stability along the outer bank. The flow between the top of vanes and the free surface accelerates and the maximum velocity of free surface flow near the flow impingement along the outer bank increases about 20% due to the installation of submerged vanes. Numerical solutions show the formations of the horseshoe vortices at the front of vanes and the lee wakes behind the vanes, which are responsible for strong local scour around vanes. Additional study on the shapes and arrangement of vanes is required for mitigate the local scour.

• Investigative Magnetic Resonance Imaging
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• v.17 no.2
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• pp.110-122
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• 2013

Purpose : To compare the image quality and ligament traceability in ankle images obtained using Volume Isotropic Turbo Spin Echo Acquisition (VISTA) MRI with and without fat suppression. Materials and Methods: The signal-to-noise ratios (SNRs) in images from a phantom and from the ankle of a volunteer were compared. Ten ankles from 10 non-symptomatic volunteers were imaged for comparisons of contrast ratio (CR) and ligament traceability. All examinations were performed using VISTA sequences with and without fat suppression on a 3T MRI scanner. The SNRs were obtained from images with subjects and without subjects (noise-only). Contrast ratios from images of the 10 ankles were acquired between fluid and tendon (F-T), F-cartilage (C), F-ligament (L), fat (f)-T, f-C and f-L. Two musculoskeletal radiologists independently scored the traceability of 7 ligaments, in sagittal, axial and coronal images respectively, based on a 4-point scale (1 as not traceable through 4 as clearly traceable). The Wilcoxon signed-rank test was used to compare the CR. Fisher's exact test and Pearson's chi-squared test were used to compare the ligament traceability. Results: The SNRs did not differ significantly between the two sequences except in bone marrow. VISTA SPAIR showed the higher CR only in F-T (p = 0.04), whereas VISTA showed higher CR in f-T (p = 0.005), f-C (p = 0.005) and f-L (p = 0.005). The calcaneofibular ligament traceability with VISTA was superior to that obtained with VISTA SPAIR (p < 0.05) in all planes. Conclusion: VISTA showed significant superiority to VISTA SPAIR in tracing CFL due to the superior CR between fat and ligament.

• Tuberculosis and Respiratory Diseases
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• v.43 no.5
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• pp.683-692
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• 1996

Background: Although most of the patients with tuberculous pleural effusions completely reabsorbed their effusions and became asymptomatic within 2 to 4 months, later surgical procedures such as decortication is needed in some patients because of dyspnea caused by pleural loculations and thickening despite anti-tuberculous chemotherapy. It is obligatory to secure adequate drainage to prevent the development of complications. But, the best methods for treating loculated tuberculous pleural effusions remain debatable. Recent several reports revealed that intrapleural instillation of fibrinolytic agents is an effective adjunct in the management of complicated empyema and may reduce the need of surgery. Purpose : The effects of catheterization with intrapleural urokinase instillation were prospectively evaluated in the patients with septated tuberculous pleural effusion, and compared with other therapeutic effects of different modalities of therapy such as repeated thoracentesis and small-bored catheterization. Methods : Forty-eight patients diagnosed with tuberculous pleurisy were randomly separated into three groups; control group(n=13), catheter group(n=12), urokinase group(n=22). In urokinase group, dose of 100.000U urokinase was instilled into the pleural cavity via a percutaneous drainage catheter for complete drainage or total dose of 700,000U of urokinase. After two hours clamping, the catheter was opened and intermittently irrigated. The early and late effectiveness of therapies was assessed by radiographically and by measuring the volume of fluid drained from the catheter. Results : There was statistically significantly better result in the urokinase group in respect of frequency of catheterization, frequency of catheter obstruction and the duration of catheterization in early effectiveness(p < 0.05). There were no difference in radiologic improvement of follow-up in later phase chest X-ray between urokinase group and catheter group in later phase(p > 0.05). But there were more failure rates in control group especially honeycomb septa in pleural effusion sonographically than former two groups. And there were no complications of urokinase such as fever or hemorrhage. Conclusion : In the treatment of septated tuberculous pleurisy, there were better results in urokinase than those of catheterization alone in early effectiveness. And there was no difference in radiographic improvement between urokinase group and catheter group. Intrapleural instillation of urokinase is an effective and safe mode of treatment for septated tuberculous pleural effusions and alleviates the need for thoracotomy.

• Journal of Dairy Science and Biotechnology
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• v.33 no.1
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• pp.47-57
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• 2015

Sodium is an essential nutrient with very important functions, including regulation of the extracellular fluid volume and active transport of molecules across the cell membranes. Since high levels of dietary sodium are associated with a high prevalence of hypertension, prehypertension, and other adverse effects on health, many national and international health organizations (WHO, FAO, etc.) recommend that sodium intake should be significantly decreased. In developed nations, cheese products, from among many processed foods, can cause high salt intake. Hence, there is an urgent need to reduce the content of salt in cheese processing, using various substitutes of sodium chloride (NaCl). In general, salt (NaCl) has been used as a food preservative to limit and (or) kill the growth of foodborne pathogens and spoilage organisms by decreasing the water activity, and to improve texture and flavor. To maintain public health, the salt content in cheese should be decreased without influencing the physicochemical properties of cheese. Therefore, the objective of this review is to outline the upcoming technologies used to reduce the salt content in different types of cheese using various substitutes.

• Journal of Korea Water Resources Association
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• v.56 no.2
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• pp.103-113
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• 2023

The river confluence is a section in which two rivers with different topographical and hyrodynamic characteristics are combined into one, and it is a section in which rapid flow, inflow of sediments, and hydrological topographic changes occur. In the confluence section, the flow of fluid occurs due to the difference in density due to the type of material or temperature difference, which is called a density flow. It is necessary to accurately measure and observe the confluence section including a certain section of the main stream and tributaries in order to understand the mixing behavior of the water body caused by the density difference. A comprehensive analysis of this water mixture can be obtained by obtaining flow field and flow rate information, but there is a limit to understanding the mixing of water bodies with different physical properties and water quality characteristics of rivers flowing with stratigraphic flow. Therefore, this study attempts to grasp the density flow through the water temperature distribution in the confluence section. Among the extensive data of the river, vertical data and water surface data were acquired, and through this, the stratification phenomenon of the confluence was to be confirmed. It was intended to analyze the mixed pattern of the confluence by analyzing the water mixing pattern according to the water temperature difference using the vertical data obtained by measuring the repair volume by installing the ADCP on the side of the boat and measuring the real-time concentration using YSI. This study can supplement the analysis results of the existing water quality measurement in two dimensions. Based on the comparative analysis, it will be used to investigate the current status of stratified sections in the water layer and identify the mixing characteristics of the downstream section of the river.

• Tuberculosis and Respiratory Diseases
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• v.60 no.3
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• pp.330-336
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• 2006

Background : Aquaporins (AQPs) may play a role in the pathogenesis of pulmonary inflammation and edema. This study investigated the role ofAQPs in acute lung injury following bleomycin inhalation in rats. Methods : Sprague-Dawley rats were treated via inhalation with 10 U/kg bleomycin hydrochloride dissolved in 5 ml of normal saline. The control rats were treated with 5 ml normal saline. The animals (n = 6-8 rats per group) were sacrificed at 4, 7, and 14 d. The changes in AQP1, AQP4, and AQP5 expression levels over time were analyzed by Western blotting. The nitrate and nitrite concentrations in the bronchoalveolar lavage fluid (BALF) were measured using a modified Griess reaction. ELISA was used to check cytokines. Results : The respiration rates were significantly higher 4 and 7 days after the bleomycin treatment compared with those of the control rats. The tidal volume was lower in rats at 4 days after the bleomycin treatment, and the wet/dry weights of the lung were significantly higher than those of the control group. The nitrite and nitrate concentrations in the BALF from the rats at 4 days after exposure to bleomycin were greater than those from the saline-treated rats. Immunoblotting studies demonstrated that the AQP1 and AQP4 expression levels were lower in the rats at 4 days. However, the AQP4 expression level was higher at 7 days. The AQP5 expression level increased at 4, 7 and 14 days after the bleomycin treatment. Conclusion : This study demonstrates that AQPs are expressed differently in bleomycin-induced pulmonary edema.

• Progress in Medical Physics
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• v.14 no.1
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• pp.34-42
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• 2003

In medical imaging, three-dimensional (3D) display using Virtual Reality Modeling Language (VRML) as a portable file format can give intuitive information more efficiently on the World Wide Web (WWW). The web-based 3D visualization of functional images combined with anatomical images has not studied much in systematic ways. The goal of this study was to achieve a simultaneous observation of 3D anatomic and functional models with planar images on the WWW, providing their locational information in 3D space with a measuring implement using VRML. MRI and ictal-interictal SPECT images were obtained from one epileptic patient. Subtraction ictal SPECT co-registered to MRI (SISCOM) was performed to improve identification of a seizure focus. SISCOM image volumes were held by thresholds above one standard deviation (1-SD) and two standard deviations (2-SD). SISCOM foci and boundaries of gray matter, white matter, and cerebrospinal fluid (CSF) in the MRI volume were segmented and rendered to VRML polygonal surfaces by marching cube algorithm. Line profiles of x and y-axis that represent real lengths on an image were acquired and their maximum lengths were the same as 211.67 mm. The real size vs. the rendered VRML surface size was approximately the ratio of 1 to 605.9. A VRML measuring tool was made and merged with previous VRML surfaces. User interface tools were embedded with Java Script routines to display MRI planar images as cross sections of 3D surface models and to set transparencies of 3D surface models. When transparencies of 3D surface models were properly controlled, a fused display of the brain geometry with 3D distributions of focal activated regions provided intuitively spatial correlations among three 3D surface models. The epileptic seizure focus was in the right temporal lobe of the brain. The real position of the seizure focus could be verified by the VRML measuring tool and the anatomy corresponding to the seizure focus could be confirmed by MRI planar images crossing 3D surface models. The VRML application developed in this study may have several advantages. Firstly, 3D fused display and control of anatomic and functional image were achieved on the m. Secondly, the vector analysis of a 3D surface model was defined by the VRML measuring tool based on the real size. Finally, the anatomy corresponding to the seizure focus was intuitively detected by correlations with MRI images. Our web based visualization of 3-D fusion image and its localization will be a help to online research and education in diagnostic radiology, therapeutic radiology, and surgery applications.