• 한국재료학회:학술대회논문집
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• 한국재료학회 2012년도 춘계학술발표대회
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• pp.73-73
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• 2012

Modern technology-driven society largely relies on hybrid electric vehicles or electric vehicles for eco-friendly transportation and the use of high technology devices. Lithium rechargeable batteries are the most promising power sources because of its high energy density but still have a challenge. Graphite is the most widely used anode material in the field of lithium rechargeable batteries due to its many advantages such as good cyclic performances, and high charge/discharge efficiency in the initial cycle. However, it has an important safety issue associated with the dendritic lithium growth on the anode surface at high charging current because the conventional graphite approaches almost 0 V vs $Li/Li^+$ at the end of lithium insertion. Therefore, a fundamental solution is to use an electrochemical redox couple with higher equilibrium potentials, which suppresses lithium metal formation on the anode surface. Among the candidates, $Li_4Ti_5O_{12}$ is a very interesting intercalation compound with safe operation, high rate capability, no volume change, and excellent cycleability. But the insulating character of $Li_4Ti_5O_{12}$ has raised concerns about its electrochemical performance. The initial insulating character associated with Ti4+ in $Li_4Ti_5O_{12}$ limits the electronic transfer between particles and to the external circuit, thereby worsening its high rate performance. In order to overcome these weak points, several alternative synthetic methods are highly required. Hence, in this presentation, novel ways using a synergetic strategy based on 1D architecture and surface coating will be introduced to enhance the kinetic property of Ti-based electrode. In addition, first-principle calculation will prove its significance to design Ti-based electrode for the most optimized electrochemical performance.

• Nuclear Engineering and Technology
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• 제16권4호
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• pp.181-194
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• 1984

변분법을 사용하여 원자로의 핵연료 관리문제를 연구하였다. 원자력 발전소에 영향을 미치는 두 함수 즉 이윤함수와 가격함수는 원자로의 연소도방정식과 최대허용출력 밀도에 대한 부등 제약조건이며, 이들은 임계성의 제약조건이 된다. 초기이윤의 변분해는 원자로에 뚜렷한 두 영역이 있음을 보여 주었다. 즉 일정 출력 영역과 최소 재고량 또는 평활 중성자속 영역이 그것이다. 이들 든 영역의 변이점은 전력에 대한 이윤과 연료에 대한 이자 지급에 상당히 중요하다. 그러므로 각 영역에서 동일 농축도의 핵연료를 가질 동일 부피의 세 영역으로 된 원자로를 최적화 하기 위하여 핵연료 주기 가격 함수가 사용 되었다. 최대 허용 출력 밀도에 대한 부등 제약조건들은 이들 부등 제약 조건이 원자로심의 어느 특정 점이나 로심주기를 통하여 항상 동일 제약조건이 되어야 한다. 원자로의 임계성과 출력밀도에 대한 동일 제약조건에 관계된 핵연료의 연소도에 대한 계차 방정식의 해를 구하였으며 최적 농축도의 위치를 구하기-위하여 구배법을 사용하였다. 이들 계산결과는 부동 제약 조건들을 적절히 적용하면 원자로를 최적화하기 위하여 비선형 최적 기술이 사용될 수 있음을 보여 주었다.

• 대한조선학회논문집
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• 제48권2호
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• pp.99-106
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• 2011

The appearance of CSR changes the concept of the hull form design as well as structural design, since the application of CSR inevitably brings the lightweight increase of a ship. Keeping the original design constraints such as principal particulars, deadweight, and speed performance, designers have to increase the volume of the hull form. As a result, the entrance angle at bow end should become larger, which results in blunter waterline shape. For a slow and full ship having high $C_B$ more than 0.85, a new concept of bow shape has been required to alleviate the increase of wave-making resistance, since it is very difficult to improve waterline and frameline shape for such a full ship. In this paper a new bow shape of Capesize Bulk Carrier was developed to improve its wave-making characteristics without incompliance with the design constraints. For loading manual calculation, NAPA software was used. FLUENT6.3.26 and WAVIS1.4 were used to evaluate resistance performance of the subject hull forms. The newly designed hull form was tested at SSPA model basin for the final confirmation of resistance and propulsion performance of the ship. It was found that the new bow shape of a Capesize Bulk Carrier improved the resistance characteristics greatly compared to a conventional bulbous bow. The other benefits of new bow shape on the manufacturability were also investigated.

• 대한한의학회지
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• 제31권3호
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• pp.1-7
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• 2010

Objectives: To introduce to TKM scientific dose conversion methods of human to animal or animal to human for new drug investigations. Methods: We searched guidelines of the FDA and KFDA, and compared them with references for drug-dose conversion from various databases such as PubMed and Google. Then, we analyzed the potential issues and problems related to dose conversion in safety documentation of new herbal drugs based on our experiences during Investigational New Drug (IND) applications of TKM. Results: Dose conversion from human to animal or animal to human must be appropriately translated during new drug development. From time to time, investigators have some difficulty in determining the appropriate dose, because of misunderstandings of dose conversion, especially when they estimate starting dose in clinical or animal studies to investigate efficacy, toxicology and mechanisms. Therefore, education of appropriate dose calculation is crucial for investigators. The animal dose should not be extrapolated to humans by a simple conversion method based only on body weight, because many studies suggest the normalization method is based mainly on body surface area (BSA). In general, the body surface area seems to have good correlation among species with several parameters including oxygen utilization, caloric expenditure, basal metabolism, blood volume and circulating plasma protein. Likewise, a safety factor should be taken into consideration when deciding high dose in animal toxicology study. Conclusion: Herein, we explain the significance of dose conversion based on body surface area and starting dose estimation for clinical trials with safety factor.

• Journal of Microbiology and Biotechnology
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• 제23권3호
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• pp.289-296
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• 2013

Cryptomonads are unicellular, biflagellate algae. Generally, cryptomonad cells cannot be preserved well because of their fragile nature, and an improved methodology should be developed to identify cryptomonads from natural habitats. In this study, we tried using several cytological fixatives, including glutaraldehyde, formaldehyde, and their combinations to preserve field samples collected from various waters, and the currently used fixative, Lugol's solution was tested for comparison. Results showed that among the fixatives tested, glutaraldehyde preserved the samples best, and the optimal concentration of glutaraldehyde was 2%. The cell morphology was well preserved by glutaraldehyde. Cells kept their original color, volume, and shape, and important taxonomic features such as furrow/gullet complex, ejectosomes, as well as flagella could be observed clearly, whereas these organelles frequently disappeared in Lugol's solution preserved samples. The osmotic adjustments and buffers tested could not preserve cell density significantly higher. Statistical calculation showed the cell density in the samples preserved by 2% glutaraldehyde remained stable after 43 days of the fixation procedure. In addition, DNA was extracted from glutaraldehyde preserved samples by grinding with liquid nitrogen and the 18S rDNA sequence was amplified by PCR. The sequence was virtually identical to the reference sequence, and phylogenetic analyses showed very close relationship between it and sequences from the same organism. To sum up, the present study demonstrated that 2% unbuffered glutaraldehyde, without osmotic adjustments, can preserve cryptomonads cells for identification, in terms of both light microscopy and phylogenetic analyses based on DNA sequences.

• 한국환경보건학회지
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• 제30권3호
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• pp.293-299
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• 2004

Traffic represents one of the largest sources of primary air pollutants in urban area. As a consequence, numerous abatement strategies are being pursued to decrease the ambient concentration of pollutants. A characteristics of most of the these strategies is a requirement for accurate data on both the quantity and spatial distribution of emissions to air in the form of an atmospheric emission inventory database. In the case of traffic pollution, such an inventory must be compiled using activity statistics and emission factors for vehicle types. The majority of inventories are compiled using passive data from either surveys or transportation models and by their very nature tend to be out-of-date by the time they are compiled. The study of current trends is towards integrating urban traffic control systems and assessments of the environmental effects of motor vehicles. In this study, a model of vehicle emission calculation by using real-time traffic data was studied. Traffic data, which are required on a street-by-street basis, is obtained from induction loops of traffic control system. It is possible that characteristics of hourly air pollutants emission rates is obtained from hourly traffic volume and speed. An emission rates model is allocated with a high resolution space by using geographic information system (GIS). Vehicle emission model was developed with a high resolution spatial, gridded and hourly emission rates.

• 한국정보통신학회:학술대회논문집
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• 한국해양정보통신학회 2002년도 추계종합학술대회
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• pp.440-447
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• 2002

본 연구에서는 호흡량 측정에 영향을 주는 요인들로부터 정확한 유량을 산출해내는 방법에 대해 고찰하고, 마취용 인공호흡기에 적용하여 수술환자의 호홉특성을 알아내는 호흡측정기를 구현하였다. 차동압력형 유량센서를 이용하여 압력, 온도, 가스구성의 상관관계에 따라 호흡량을 계측하였으며, 휴대형 기기에 적합하도록 전력 효율을 최대화 할 수 있게 시스템을 설계하였다. 구현 시스템은 크게 아날로그 인터페이스(analog interface)부, 신호처리부, 그리고 화면출력부로 나눌 수 있다. 아날로그 인터페이스부는 차동 압력 유량 센서와 차동 압력 센서로 구성된다. 전력소모를 최소화하기 위하여 여러 가지 기능을 단일소자로 수행할 수 있고, 저전력의 8비트 RISC 계열인 AVR프로세서를 중앙처리장치로 선택하였다. 데이터 전송부에서는 직렬(serial)통신(RS232, SPI)으로 측정된 값들의 출력 파형을 PC화면에 표시하거나 마취기로 전송한다. 차동 압력과 유량의 비선형적 관계를 선형화하였고, 센서 보정 기능은 일정 주기로 보정을 자동적으로 수행함으로써, 보다 안정적인 동작이 가능하게 한다. 아날로그 필터와 고속의 디지털 신호처리 알고리즘 구현으로 생체신호의 노이즈를 줄일 수 있었다. 작고, 가벼우며, 저전력인 시스템의 특징은 응급 환자나 이동중인 환자에게 적용될 수 있으며, 가래, 침, 습기와 같은 이물질에 영향이 적은 유량 센서의 사용으로 점액의 발생이 많은 마취기에서 유용하게 사용될 수 있다.

• 대한기계학회논문집
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• 제18권1호
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• pp.139-149
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• 1994

A numerical simulation of unsteady axisymmetric turbulent flow was performed for a reciprocating engine including port/valve assembly. The governing equations based on a nonorthogonal coordinate formulation with Cartesian velocity components were used and discretised by the finite volume method with non-staggered variable arrangements. The modified $\kappa-\xi$. turbulence model which included the effect of compressibility was used. The results of twodimensional transient calculation for the axisymmetric configuration were compared with the experimental data. Although slightly low rms velocity was predicted compared to the experimental data, predicted velocity distributions at the valve exit and in-cylinder region showed good agreements with the experimental data. The flow at the valve exit was separated at the same valve lift position with the experimental data. Two vortices incylinder region were generated during the initial intake process. The clockwise main vortex became strong and moved upward to the top wall. The counter-clockwise second vortex became weak and stick to the upper left corner of the cylinder. After middle intake process, new vortex adjacent to upper cylinder wall appeared by the piston motion and therefore, the in-cylinder flow was formed into three vortices. The cylinder pressure just before bottom dead center of piston was higher than inlet pressure and then the reverse flow occured at the valve exit. The in-cylinder flow characteristics were strongly dependent on piston motion, but insensitive to valve motion.

• 대한기계학회논문집 C: 기술과 교육
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• 제3권1호
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• pp.15-21
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• 2015

가스 엔진 히트 펌프는 가스 엔진의 축동력으로 압축기를 구동하는 시스템으로 전력을 거의 사용하지 않고, 엔진 폐열을 활용하기 때문에 하절기와 동절기에 전력 Peak 를 억제하는 공조기로 주목을 받고 있는 제품이다. 제품 개발 시 시스템 성능 예측이 중요하므로 이를 위해 초기 설정한 운전점에서 열교환기 및 압축기의 특성을 반영하여 반복 계산을 수행하면 최종적인 운전점을 도출할 수 있고, 가스 엔진의 성능 데이터를 활용하면 가스 엔진 히트 펌프의 정확한 효율을 예측할 수 있다. 난방 성능을 예측할 때에는 엔진 폐열이 시스템에 공급되기 때문에 외부 열을 흡입하는 구간과 엔진 폐열을 흡입하는 구간을 동시에 고려해야 예측의 정확도를 높일 수 있다. 25 마력 가스 엔진 히트 펌프의 성능을 예측한 값은 실제 측정한 값과 비교하였을 경우 5% 정도의 오차가 발생하며 향후 성능 예측 모델을 구성되는 부품 특성을 반영하면 오차의 폭이 감소될 것으로 예상된다.

• 대한화학회지
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• 제20권2호
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• pp.118-128
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• 1976

액체에 대한 significant structure theory 와 상의 전이에 대한 Bragg-Williams근사를 사용하여 액정 화합물인 p-azoxyanisole의 열역학적 성질을 nematic phase와 isotropic phase의 온도범위에 걸쳐 계산하였다. Isotropic phase는 일반적인 액체로 보았으며 nematic phase는 액체적인 성질외에도 분자쌍극자의 배열에 의한 영향도 고려하였다. p-Azoxyanisole의 액체적인 성질은 significant structure theory로 기술하였으며 분자쌍극과 배열에 의한 영향은 Bragg-Williams 근사로써 고려하였다. 부피, 증기압, 정압비열, 열팽창계수, nematic-isotropic 전이점에서의 엔트로피 엔탈피 변화, 절대엔트로피, Helmholtz free energy등을 계산하여 실험치와 비교하였다.