• Title/Summary/Keyword: Vitamin-D

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Protective Effect of Quercus salicina Blume Extract in Calcium Oxalate Urolithiasis Model (참가시나무 추출물이 신장결석유도 랫드에 미치는 저해효과)

  • Heo, Jin-Sun;Kim, Jong-Bok;You, Han-Choon;Lee, Min-Su;Choi, Jong-Won
    • Korean Journal of Plant Resources
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    • v.25 no.5
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    • pp.507-516
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    • 2012
  • Kidney stones occur in approximately 1% of the population during their lifetime. Although the development of extracorporeal shock wave lithotripsy (SWL) has revolutionized the theraphy of urolithiasis, the rate of recurrence of urothiasis, the rate of recurrenece of stones after SWL is about 50% within 10 years, which still represents serious problems for patienes. So to clarify the mechanism of Urocalum, and QS (Quercus salicina Blume) extract in the treatment of urolithiasis. Rat calcium oxalate urolithiasis was induced by oral administration of ethylene glycol and the vitamin D3 analog alfacalcidol for 14 days and QS extract was given to rats. After the last administration, we measured in urine, serum and renal oxidative stress marker. Ethylene glycol and alfacalcidol treatment increased BUN, creatinine, uric acid and XO. This increase was significantly suppressed by the administration of QS extract. These finding suggest that the QS extract plays a role in the prevention of stone formation and recureence in urolithiasis.

Evaluation of Nattokinase for Antithrombotic Effect and Pharmacological Efficacy by a Biological Test and Clinical Trial (동물 및 인체시험을 통한 Nattokinase의 항응고 작용 및 섬유소 용해능 평가)

  • Kim, Jae-Bum;Yoo, Chul-Bae;Shin, Hyun-Man;Jung, Joon-Ki;Jang, Hyung-Wook
    • KSBB Journal
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    • v.26 no.5
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    • pp.393-399
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    • 2011
  • Bacillus subtilis natto producing high level of a fibrinolytic enzyme was selected and Ultra Nattokinase$^{(R)}$ was manufactured by fermentation and purification. It was performed the evaluation of the antithrombotic effect of Ultra Nattokinase$^{(R)}$ (20,000 FU/g) with rat blood plasma. The maximum aggregation (inhibition ratio) was 71% (0%), 69% (2.8%), 62% (12.7%), 16% (77.5%) and 9% (87.3%), respectively, in the order of 0, 5, 10, 50 and 100 mg/mL of Ultra Nattokinase$^{(R)}$ solutions. Ultra Nattokinase$^{(R)}$ had antithrombotic effect, which was associated with the suppression of collagen-induced platelet aggregation. Ultra Nattokinase$^{(R)}$ in the topic of the FDP (fibrinogen degradation products) in blood coagulation tests showed a significant increasing trend. And based on the daily record of meal 39 people of ITT (what ?) group consisted with 19 people of NP (what ?) group and 20 people of PN (what ?) group except four people, two people who took vitamin K affecting the experiment and two people who took alcohol, finding to be taken Ultra Nattokinase$^{(R)}$ showed an increase in the FDP value after four weeks. In addition, FDP value of 41 people of ITT group except two people having metabolic syndrome was increased by Ultra Nattokinase$^{(R)}$.

Nutritional Functions of Milk and Dairy Products in Improving Human Health

  • Chon, Jung-Whan;Kim, Hyunsook;Kim, Dong-Hyeon;Lee, Soo-Kyung;Kim, Hong-Seok;Yim, Jin-Hyuk;Song, Kwang-Young;Kim, Young-Ji;Kang, Il-Byung;Jeong, Dana;Park, Jin-Hyeong;Jang, Ho-Seok;Seo, Kun-Ho
    • Journal of Dairy Science and Biotechnology
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    • v.34 no.3
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    • pp.145-155
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    • 2016
  • Cow's milk and dairy products are elements of the human diet that could play an important role in improving human health. The macronutrients and micronutrients found in milk could supply the nutrients required to maintain human health. Among them, milk-derived bioactive peptides have been identified as potential ingredients found in health promoting functional foods. These bioactive peptides target diet-related chronic diseases, particularly non-communicable ones such as cardiovascular disease, diabetes and obesity. Additionally probiotics such as lactic acid bacteria (LAB) are can be considered live microorganisms that confer health benefits for the host-, when administered in adequate amounts. Further, the calcium, vitamin D, and protein content of milk and dairy products could play a role in proving bone health. The effect of milk and calcium on bone mineral density could prevent against fracture, osteoporosis and rickets. Furthermore, milk and dairy products also contain which factors that, which protect against dental caries (anti-cariogenic properties). This paper reviews the various nutritional functions of milk and dairy products in improving human health.

Comparison of Growth and Essential Oil Composition in Two Hydroponically Grown Species of Thymes at Different Nutrient Solution Strength (수경재배시 배양액 내 이온농도에 따른 두 종의 백리향 생육 및 정유 성분 비교)

  • 김예희;이문정;박권우
    • Journal of Bio-Environment Control
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    • v.9 no.2
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    • pp.79-84
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    • 2000
  • The growth and quality differences between common thyme(Thymus vulgaris L.) and lemon thym (Thymus$\times$citriodorus) were investigated. They were grown in a hydroponics culture system (DFT) with a nutrient solution developed by the European Vegetable R&D Center in Belgium. Nutrient solution ionic strength used were 1.2, 2.4, 4.8 and 7.2 mS.cm-1. The dry matter of two thymes were increased with increasing ionic strength, while shoot length, root length and fresh weight were decreased. Chlorophyll content was higher in lemon thyme, while vitamin C content and essential oil content were higher in common thyme. The essential oil content showed a similar trend as those of growth. The main compostion of essential oil were thymol and carvacrol in common thyme, and geraniol and $\alpha$-citral in lemon thyme. The highest content of these compounds was obtained in 1.2mS.cm-1 treatment. Consequently, the ionic strength of 1.2mS.cm-1 was suitable for the production of quality thymes.

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The association of potassium intake with bone mineral density and the prevalence of osteoporosis among older Korean adults

  • Ha, Jinwoo;Kim, Seong-Ah;Lim, Kyungjoon;Shin, Sangah
    • Nutrition Research and Practice
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    • v.14 no.1
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    • pp.55-61
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    • 2020
  • BACKGROUND/OBJECTIVES: Osteoporosis is characterized by low bone mass and results in vulnerability to fracture. Calcium and vitamin D are known to play an important role in bone health. Recently, potassium has been identified as another important factor in skeletal health. We examined the link between potassium intake and bone health among the Korean older adult population. SUBJECTS/METHODS: This retrospective, cross-sectional study included 8,732 men and postmenopausal women over 50 years old who completed the Korean National Health and Nutrition Survey (KNHANES) between 2008 and 2011. Potassium consumption was evaluated using a 24-hour recall method. Bone mineral density (BMD) was measured at three sites (total hip, femur neck, and lumbar spine) by dual-energy X-ray absorptiometry (DEXA). Multinomial logistic regression was used to examine the link between potassium intake and prevalence of osteoporosis and osteopenia, after controlling for potential confounding variables. RESULTS: The BMD of the total femur and Ward's triangle were significantly different according to the potassium intake among men (P = 0.031 and P = 0.010, respectively). Women in the top tertile for potassium intake showed higher BMD than those in the bottom tertile at all measurement sites (all P < 0.05). Daily potassium intake was significantly related to a decreased risk of osteoporosis at the lumbar spine in postmenopausal women (odds ratios: 0.68, 95% confidence interval: 0.48-0.96, P trend = 0.031). However, the dietary potassium level was not related to the risk of osteoporosis in men. CONCLUSION: Current findings indicate that higher dietary potassium levels have a favorable effect on bone health and preventing osteoporosis in older Korean women.

The Dietary Intake and Nutritional Status of Fatty Liver Patients (지방간 환자의 식품섭취 및 영양상태에 관한 조사-남성을 중심으로-)

  • 이석화;기춘석;장유경
    • Korean Journal of Community Nutrition
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    • v.3 no.4
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    • pp.622-629
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    • 1998
  • This study was performed to investigate the effect of dietary intakes and nutritional status for fatty liver male patients with fatty livers. General characteristics, nutritional knowledge, and dietary intakes were obtained from fatty liver male patients aged 20-60yr living in Seoul and Kyunggi province by individual interview and blood samples. The Results were as follows : the mean age of the subjects was 39yrs. Old and over half the subjects were overweight. Although nutritional knowledge, recognition, and accuracy scores were good, these did not affect the subject's health. The average alcohol intake of subjects was 79.8g/day and the drinking duration was 5-40yrs(average : 17yrs). The subjects drank alcohol over 4tiles/week and preferred Soju. Most side dishes taken with alcohol drinking by the subjects were foods from animal sources. Half of the subjects also drank alcohol the next day for breakfast as a hangover-chaser. The reasons for drinking were due to social relationships and by habit. Vitamin D and folate were lower than the RDA for Koreans, and other nutrient amounts were higher than the RDA. The amounts of aspartate amino-transferase(AST), Alanine amino-transferase(ALT), ${\gamma}$-glutamyl transpeptidase(${\gamma}$-GTP), Triglyceride(TG) for the subjects were higher. In conclusion, fatty liver patients drank excessively and frequently. It seems that heavy alcohol drinking is more prone to overweight or obese people and contributes to fatty livers. Therefore, the subjects need to be taken effectively educated about alcohol-induced liver damage and the importance of a balanced diet for on healthy liver.

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A New Potato Cultivar "Early Valley", with High Yield and Early Maturity

  • Lim, H.T.;Dhital, S.P.;Khu, D.M.;Choi, S.P.;Kang, C.W.;Kim, T.J.;Mo, H.S.;Hwang, W.N.;Lee, W.J.
    • Korean Journal of Breeding Science
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    • v.41 no.1
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    • pp.61-67
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    • 2009
  • "Early Valley", is an early maturing potato cultivar with high yield potential. "Early Valley" is a clonal selection resulting from the cross between 'Suncrisp' and 'A87109-10'. It has medium plant height and light green foliage. "Early Valley" has medium flowering habit and white flowers. Tubers are smooth, yellow skin, light yellow flesh, round tuber shape, medium eye depth, and medium dormancy and good keeping quality. It has stable yield under wide range of climatic conditions. "Early Valley" is resistance to late blight, but moderately susceptible to common scab and hollow heart. This cultivar is also resistant to potato rotting at harvesting during the raining season. "Early Valley" has high level of antioxidant activity (about three times higher) and vitamin C (higher by 40%) than the 'Superior'. This cultivar has high level of tuber uniformity and capable of yielding 36.56 t/ha which is 17.07% higher than the control potato cultivar 'Superior' under optimum agronomical practices.

Diet and Metabolic Disease Risk Related to Sarcopenia in Pre- and Postmenopausal Adult Women: Based on the Korea National Health and Nutrition Examination Survey (2009-2011) (폐경 전·후 성인 여성에서 근감소증과 관련된 식생활 요인 및 대사성 질환 위험도: 국민건강영양조사(2009-2011) 자료를 활용하여)

  • Kim, Mi Hyun
    • Journal of the Korean Society of Food Culture
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    • v.36 no.4
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    • pp.401-411
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    • 2021
  • Diet is important for muscle health and offers a protective effects against the loss of skeletal muscle mass and physical functions with advancing age. We analyzed the relationship between diet, metabolic disease risk, and sarcopenia in Korean female adults using the 2009-2011 Korea National Health and Nutrition Examination Survey (KNHANES). A total of 2038 adult women aged 50-64 years were classified into four groups based on the diagnosis of menopause and sarcopenia. The groups were the non-menopause and non-sarcopenia group (NMNS, n=249), the non-menopause and sarcopenia group (NMS, n=14), the menopause and non-sarcopenia group (MNS, n=1,653), and the menopause and sarcopenia group (MS, n=122). The socio-demographics, anthropometrics, blood profile, and dietary data of the subjects were collected. Those who were in both the sarcopenia groups were more obese (p<0.001), had greater waist circumferences (p<0.001), higher body mass index (p<0.001), and higher obesity rates (p<0.001) after adjustment for covariants. Both the sarcopenia groups also had higher plasma levels of total cholesterol (p<0.001), HbA1c (p=0.001), and vitamin D (p=0.020) than both the non-sarcopenia groups. Both the sarcopenia groups demonstrated a decreased intake of calcium (p=0.05), potassium (p=0.008), and niacin (p=0.008) than both the non-sarcopenia ones. Among the four groups, the NMS group showed the highest levels of total cholesterol, obesity, and lowest intake of micronutrients such as calcium, niacin, and potassium. Thus, muscle mass maintenance through weight control and adequate nutrient intake appears to demonstrate a potential association with preventing sarcopenia in Korean middle-aged women.

Differences in Nutrient Intake with Homemade versus Chef-Prepared Specific Carbohydrate Diet Therapy in Inflammatory Bowel Disease: Insights into Dietary Research

  • Morrison, Alex;Braly, Kimberly;Singh, Namita;Suskind, David L.;Lee, Dale
    • Pediatric Gastroenterology, Hepatology & Nutrition
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    • v.24 no.5
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    • pp.432-442
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    • 2021
  • Purpose: The aim of this study was to evaluate the nutrient content consumed by children and adolescents on home-prepared versus chef-prepared specific carbohydrate diets (SCD) as therapy for inflammatory bowel disease (IBD). Methods: Dietary intake of two cohorts with active IBD initiating the SCD over 12 weeks was assessed. The home-prepared cohort received detailed guidance from dietitians on implementation of the SCD. The chef in the other cohort was knowledgeable in the SCD and prepared meals from a fixed set of recipes. Data from 3-day diet diaries at 4 different time points were collected. US Recommended Daily Allowances (RDA) were calculated for macronutrients, vitamins, and minerals. Results: Eight participants on the homemade SCD and 5 participants on the chef-prepared SCD were included in analysis. Mean % RDA for energy intake was 115% and 87% for homemade and chef-prepared groups (p<0.01). Mean % RDA for protein intake was 337% for homemade SCD and 216% for chef-prepared SCD (p<0.01). The homemade SCD group had higher mean % RDA values for vitamin A and iron, while the chef-prepared SCD group had higher intake of vitamins B1, B2, D, phosphorus and zinc (p<0.01 for all). Conclusion: The SCD implemented homemade versus chef-prepared can result in significantly different intake of nutrients and this may influence efficacy of this dietary therapy. Meal preparation dynamics and the motivation of families who pursue dietary treatment may play an important role on the foods consumed and the outcomes on dietary therapy with the SCD.

Factors associated with paravertebral muscle cross-sectional area in patients with chronic low back pain

  • Cankurtaran, Damla;Yigman, Zeynep Aykin;Umay, Ebru
    • The Korean Journal of Pain
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    • v.34 no.4
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    • pp.454-462
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    • 2021
  • Background: This study was performed to reveal the relationships between the cross-sectional areas (CSAs) of the paraspinal muscles and the severity of low back pain (LBP), including the level of disability. Methods: This single-center cross-sectional study was conducted on 164 patients with chronic LBP. The effects of demographic characteristics, posture, level of physical activity, disc herniation type, and sarcopenia risk on the CSAs of paraspinal muscles were evaluated along with the relationship between the CSAs and severity of pain and disability in all patients. The CSAs of paraspinal muscles were evaluated using the software program Image J 1.53. Results: A negative significant correlation was found between age and the paraspinal muscle's CSA (P < 0.05), whereas a positive correlation was present between the level of physical activity and the CSA of the paraspinal muscle at the L2-3 and L3-4 levels. The CSAs of paraspinal muscles in patients with sarcopenia risk was significantly lower than those in patients without sarcopenia risk (P < 0.05). The CSAs of paraspinal muscles at the L2-3 and L3-4 levels in obese patients were significantly higher than those in overweight patients (P = 0.028, P = 0.026, respectively). There was no relationship between the CSAs of paraspinal muscles and pain intensity or disability. Conclusions: Although this study did not find a relationship between paraspinal CSAs and pain or disability, treatment regimens for preventing paraspinal muscles from atrophy may aid pain physicians in relieving pain, restoring function, and preventing recurrence in patients with chronic LBP.