• Title/Summary/Keyword: Visual cell

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Estimation of Visual Stimulus Intensity From Retinal Ganglion Cell Spike Trains Using Optimal Linear Filter (최적선형필터를 이용한 망막신경절세포 Spike Train으로부터의 시각자극 세기 변화 추정)

  • Ryu, Sang-Baek;Kim, Doo-Hee;Ye, Jang-Hee;Kim, Kyung-Hwan;Goo, Yong-Sook
    • Journal of Biomedical Engineering Research
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    • v.28 no.2
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    • pp.212-217
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    • 2007
  • As a preliminary study for the development of electrical stimulation strategy of artificial retina, we set up a method fur the reconstruction of input intensity variation from retinal ganglion cell(RGC) responses. In order to estimate light intensity variation, we used an optimal linear filter trained from given stimulus intensity variation and multiple single unit spike trains from RGCs. By applying ON/OFF stimulation(ON duration: 2 sec, OFF duration: 5 sec) repetitively, we identified three functional types of ganglion cells according to when they respond to the ON/OFF stimulus actively: ON cell, OFF cell, and ON-OFF cell. Experiments were also performed using a Gaussian random stimulus and a binary random stimulus. The input intensity was updated once every 90 msec(i. e. 11 Hz) to present the stimulus. The result of reconstructing 11 Hz Gaussian and binary random stimulus was not satisfactory and showed low correlation between the original and reconstructed stimulus. In the case of ON/OFF stimulus in which temporal variation is slow, successful reconstruction was achieved and the correlation coefficient was as high as 0.8.

The Effect of Laser Irridation on the Ultrastructure of Retina (Laser 조사가 망막의 미세구조에 미치는 영향)

  • Kim, Douk Hoon;Mun, Jung Hak
    • Journal of Korean Ophthalmic Optics Society
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    • v.1 no.1
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    • pp.15-22
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    • 1996
  • The fine structure of retinal tissue was studied to investigate on effect of Laser irridation on the ICR mouse with electron microscope. The results obtained were as follows: 1. At the normal groups, the most retinal layers were a complex structure, consisting of several specific cells and nerve fiver. 2. In the increasing time of Laser irridation, each cell layer of retina was not uniform of the structure and band. The visual cells were severely heterochromatin swelling of cytoplasm, irregular shape & heterochromatin of nuclear, and disappear of some cytoplasm. The nucleus and nerve fiber of retinal layer was a very irregular shape, formation of vesicle, not identify of each intercellular boundary. The pigment epithelial cells were not an uniform, a large vesicle formation of cytoplasm, and a condensation & very irregular shape of nucleus.

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Study on Visual Patterns about Spatial Dimensions - Centered on the Golden Ratio, Fibonacci Sequence, and Fractal Theory - (공간 차원에 관한 시각적 패턴 연구 - 황금비, 피보나치 수열, 프랙털 이론을 중심으로 -)

  • Kim, Min-Suk;Kim, Kai-Chun
    • Korean Institute of Interior Design Journal
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    • v.23 no.1
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    • pp.88-95
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    • 2014
  • This study intended arousal of other viewpoints that deal with and understand spaces and shapes, by describing the concept of 'dimensions' into visual patterns. Above all, the core concept of spatial dimensions was defined as 'expandability'. Then, first, the 'golden ratio', 'Fibonacci sequence', and 'fractal theory' were defined as elements of each dimension by stage. Second, a 'unit cell' of one dimension as 'minimum unit particles' was set. Next, Fibonacci sequence was set as an extended concept into two dimensions. Expansion into three dimensions was applied to the concept of 'self-similarity repetition' of 'Fractal'. In 'fractal dimension', the concept of 'regularity of irregularity' was set as a core attribute. Plus, Platonic solids were applied as a background concept of the setting of the 'unit cell' from the viewpoint of 'minimum unit particles'. Third, while 'characteristic patterns' which are shown in the courses of 'expansion' of each dimension were embodied for the visual expression forms of dimensions, expansion forms of dimensions are based on the premise of volume, directional nature, and concept of axes. Expressed shapes of each dimension are shown into visually diverse patterns and unexpected formative aspects, along with the expression of relative blank spaces originated from dualism. On the basis of these results, the 'unit cell' that is set as a concept of theoretical factor can be defined as a minimum factor of a basic algorism caused by other purpose. In here, by applying diverse pattern types, the fact that meaning spaces, shapes, and dimensions can be extracted was suggested.

Study on the Implementation of Primitive Visual Cortex Model in Retina Using Gabor Wavelet (가버 웨이블릿을 이용한 원시 시각 피질 모델 구현에 관한 연구)

  • Lee, Youngseok
    • The Journal of Korea Institute of Information, Electronics, and Communication Technology
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    • v.13 no.6
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    • pp.477-482
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    • 2020
  • The human visual cortex has the characteristic that reacts sensitively to stimuli with special directional or temporal frequency changes while it is insensitive to selective stimuli of spatial phases. In this paper we implemented the model of complex cell using an image estimation iterative algorithm by Gabor wavelet transform. The performance of implemented model evaluated the consistency between the physiological experimental results in related papers. The implemented model is limited in the complete model of the receptive field in the retina where simple cells and complex cells are distributed together. But the implemented model express the reaction of the complex cells from the point of view of the detection of corners and edges.

Establishment of the cell lines with plant regeneration ability and low ploidy level in Dianthus acicularis with the aid of flow cytometry analysis

  • Shiba, Tomonori;Mii, Masahiro
    • Proceedings of the Korean Society of Plant Biotechnology Conference
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    • 2005.11a
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    • pp.112-119
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    • 2005
  • Efficient plant regenerationsystem from cell suspension cultures was established in D. acicularis (2n = 90) by monitoring ploidy level and visual selection of the cultures. The highly regenerable cell lines selected maintained original ploidy level and consisted of compact cell clumps with yellowish color and relatively moderate growth, suggesting that it is possible to select visually the highly regenerable cell lines with the original ploidy level. All the regenerated plantlets from the highly regenerable cell cultures exhibited normal phenotypes and no variations in ploidy level were observed by flow cytometry (FCM) analysis.

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The number and distribution of reinal ganglion cells in a Korean native cattle (한우(韓牛) 안구(眼球)의 망막신경절세포(網膜神經節細胞) 수(數)와 분포(分布)에 관(關)한 연구(硏究))

  • Kim, Moo-kang;Cho, Sung-whan;Ryu, Si-yun;Kim, Kyo-joon;Kim, Song-keun;Shin, Ta-kyun;Lee, Gang-iee
    • Korean Journal of Veterinary Research
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    • v.29 no.1
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    • pp.1-6
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    • 1989
  • The number and distribution of the retinal ganglion cells in the 2 years old Korean native cattle was determined from whole fiat mounted preparation stained with methylene blue and thionin. The results were summarized as follows. 1. The total number of retinal ganglion cells was estimated to be 3,085,200 in the bovine retina ranging from $2,214mm^2$ in total area. 2. Visual streak was recognized at the area 2.5mm superior to the optic disc and ganglion cell density drops off rapidly to the directions superior to and inferior to the visual streak. 3. Area centralis ($6,800cells/mm^2$) was located at the area 10mm temporally from the point of 3mm superior to the optic disc. 4. The number of ${\alpha}-type$ ganglion cells (above $15{\mu}$) was 57,000 in the bovine retina and ${\alpha}-type$ ganglion cells constituted 18.5% of the total cells. 5. The relative frequency of ${\alpha}-type$ ganglion cells was higher in the peripheral regions than in the visual streak, especially higher in the superior-temporal quadrant than in other region of the bovine retina.

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A Study on Image Recognition by Orientation Information (방향 정보 처리에 의한 영상 인식에 관한 연구)

  • Cho, Jae-hyun;Kim, Jin-hwan;Lee, Jong-hee
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2009.10a
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    • pp.308-309
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    • 2009
  • Human vision information processing has many characteristics when image information is transmitted from retina to visual cortex. Among them, we analyze the sensibility of the orientation on an image and compare the recognition rates by the response_weight of the vertical, horizontal and diagonal orientation. In statistics analysis, we show that a particular simple cell responds best to a bar with a vertical orientation. After then, we will apply the characteristics to Human visual system.

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Single Cell Gel Electrophoresis (comet assay) to Detect DNA Damage and Apoptosis in Cell Level (DNA damage와 Apoptosis를 정량화하는 단세포전기영동법)

  • 류재천;김현주;서영록;김경란
    • Environmental Mutagens and Carcinogens
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    • v.17 no.2
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    • pp.71-77
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    • 1997
  • The single cell gel electrophoressis(SCGE) assay, also known as the comet assay, is a rapid, simple, visual and sensitive technique for measuring and analysing DNA breakage in mammalian cells. The SCGE or comet assay is a promising test for the detection of DNA damage and repair in individnal cells. It has widespread potential applications in DNA damage and repair studies, genotoxicity testing and biomonitoring. In this microgel electrophoresis technique, cells are embedded in agarose gel on microscope slides, iysed and electrophoresed under alkaline conditions. Cells with increased DNA damage display increased migration of DNA from the nucleus towards the anode. The length of DNA migration indicates the amount of DNA breakage in the cell. The comet assay is also capable of identifying apoptotic cells which contain highly fragmented DNA. Here we review the development of the SCGE assay, existing protocols for the detection and analysis of comets, the relevant underlying principles determining the behaviour of DNA and the potential applications of the technique.

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Differential Diagnosis and Management of a Pituitary Mass with Renal Cell Carcinoma

  • Hwang, Joo Min;Kim, Yong Hwy;Kim, Tae Min;Park, Sung Hye
    • Journal of Korean Neurosurgical Society
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    • v.54 no.2
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    • pp.132-135
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    • 2013
  • The small pituitary mass was incidentally found in 40-years-old women with renal cell carcinoma. The endocrinological and ophthalmological evaluation revealed no deficit and the short-term follow-up was recommended. In 6 months later, the visual disturbance was reported and the size of mass was increased. The tumor was removed totally via the trans-sphenoid approach. The post-operative endocrinological insufficiency was not noticed. During one year of follow-up period, there was no evidence of recurrence without adjuvant radiotherapy. The clinical features of pituitary metastasis from renal cell carcinoma were similar to those of pituitary adenoma. The possibility of pituitary metastasis should be kept in mind in patients with sellar mass and renal cell carcinoma.

A Study on Image Recognition by Orientation Information (방향정보처리에 의한 영상 인식에 관한 연구)

  • Cho, Jae-Hyun;Kim, Jin-Hwan;Lee, Jong-Hee
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.13 no.11
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    • pp.2283-2288
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    • 2009
  • There are a lot of characteristics in Human visual information processing when image information is transmitted from retina to visual cortex. Among them, we analyze the sensibility of the orientation and cortical magnification on an image. The fact that the small fovea is allotted a large area on the cortex is called the cortical magnification factor. We compare recognition rates by weight of vertical, horizontal and diagonal response. In statistics analysis, we show that a particular simple cell responds best to a bar with a vertical orientation. After then, we will apply the characteristics to Human visual system.