• Asian Pacific Journal of Cancer Prevention
• /
• 제15권18호
• /
• pp.7805-7809
• /
• 2014

Objective: To explore the clinical efficacy and prognostic factors of chemoreduction combined with topical treatment of advanced intraocular retinoblastoma (RB). Materials and Methods: A total of 22 eyes from 17 children with RB were selected for the study and treated with chemoreduction combined with topical cryotherapy, transpupillary thermotherapy (TTT) or episcleral plaque brachytherapy. Clinical and follow-up data were retrospectively analyzed. Results: All children received 2~6 courses of chemoreduction treatment, ($4.5{\pm}0.8$ courses on average); 17 eyes from 13 children were treated by chemoreduction combined with cryotherapy or TTT and 5 eyes from 4 children with chemoreduction combined with $^{125}I$ episcleral plaque brachytherapy. The eye retention rate was 81.8% (18/22), among which 38.9% (7/18) featured restored or maintained good vision. Postoperative follow-up period was 7 to 34 months, ($18.6{\pm}5.2$ months on average). The recurrence rate was 41.2% (7/17), among which 57.1% (4/7) were controlled by supplementing or appending cryotherapy or TTT treatment during the follow-up period. The tumor basal diameter and thickness were significantly reduced (P<0.05 or P<0.01) after treatment. All children demonstrated different degrees of hair loss, 70.6% (12/17) with different degrees of gastrointestinal reactions, 5.88% (1/17) with neutropenia and 11.8% (2/17) being seriously infected during the chemotherapeutic treatment. Univariate and logistic regression analysis showed that tumor basal diameter before treatment had a significant effect on the prognosis (P<0.01). Conclusions: Chemoreduction combined with topical therapy can effectively control RB in the short term, and tumor basal diameter before treatment is an independent risk factor for prognosis.

• 농촌계획
• /
• 제21권1호
• /
• pp.117-127
• /
• 2015

This study evaluated properties and items for selecting on a forest healing village. In order to assign a weight value-between factors, this study was conducted the primary survey first and then the secondary survey for measuring the importance of items. Experts'surveys were conducted on 3 items on level 1, 9 items on level 2, 35 items on level 3 with use of AHP technique. In level 1, the main analysis result was that physical resource properties(0.387) indicated the highest importance. in level 2, healing resources of physical properties(0.402), community participation of human resource properties(0.425), and business competency in part of vision(-.438) showed the highest importance. The analysis result of 35 items on level 3 was that in physical resources properties, securing public land in the village(0.220), possessing recreation space(0.440) and resources available for link with healing(0.413) showed the highest importance. In part of human resources properties, the average age of residents(0.465), commitment to the promotion of the villagers(0.367) and support of local leaders(0.318) showed the highest importance. Adequacy of development plan(0.274), forest work experience-related(0.293), and building profit sharing system(0.282) were also evaluated to have a relatively high importance.

• 융합정보논문지
• /
• 제10권7호
• /
• pp.223-231
• /
• 2020

노인 운전자는 기능저하로 인해 사고 위험성이 증가하지만 스스로 변화를 점검하는 자가-조절 능력 또한 발달한다. 이에 실제 노인 운전자가 운전 능력과 위험성 변화에 대응하는 특성에 대한 정보는 노인의 운전 능력 평가 현장과 연구에 의미있는 근거를 제공할 수 있다. 따라서 본 연구의 목적은 한국 노인 운전자의 운전 위험성 자각 특성을 운전 중 행동과 운전관련 기능변화의 측면에서 분석하여 노인 운전자 평가를 위한 기초 자료를 제공하는 것이다. 지역사회에 거주하는 노인 운전자 500명을 대상으로 자가-보고식 평가를 실시하고 노인 운전자의 운전 위험성 자각 징후를 분석하였다. 그 결과 다수의 노인 운전자가 시각 및 청각이 저하되거나 운전 여건 변화에 적응하는데 어려움을 느낄 때 운전 위험성을 자각하는 특성이 있음을 확인하였다. 반면, 약물 복용이나 간질, 발작, 의식손실 등 의학적 건강 상태 변화에는 둔감하게 반응하는 특성이 확인되었다. 본 연구 결과가 고령화가 가속화되는 한국의 노인 운전자 안전 관리에 기여할 수 있기를 기대한다.

• Journal of Medicine and Life Science
• /
• 제16권3호
• /
• pp.96-100
• /
• 2019

Postural tachycardia syndrome (POTS) is common, although not so well-known variant of cardiovascular autonomic disorder characterized by an excessive heart rate increase on standing. POTS is probably underdiagnosed due to the heterogeneity in both presentation and etiology. This study aimed to evaluate the clinical and autonomic features in patients with POTS. We reviewed the medical records of patients with POTS. Medical records include onset age, sex, presenting symptoms, body mass index (BMI) and prognosis. All patients had an autonomic function and laboratory tests. Ninety-nine patients met the inclusion criteria for POTS (51.5% male; mean±SD age, 20.0±9.7 years; mean±SD, BMI 21.9±3.9). Common presenting symptoms were a brief loss of consciousness, dizziness, blurred vision and headache. Autonomic function tests showed abnormal quantitative sudomotor axon reflex testing in 20 patients of 99 POTS patients. The abnormal post-ganglionic sympathetic sudomotor function is generally considered to reflect a neuropathic form of POTS. In treatments, 83 patients were treated by non-pharmacological management including lifestyle changes and 16 patients required the initiation of pharmacological therapies. Most patients with POTS showed a relatively favorable prognosis. POTS is a chronic disease with a substantial subset of patients recovering within a few years after the initial presentation. Future efforts should focus on better understanding of POTS pathophysiology and designing randomized controlled trials for the selection of more effective therapy.

• Annals of Clinical Neurophysiology
• /
• 제20권1호
• /
• pp.31-35
• /
• 2018

Background: Although postural instability is one of the major symptoms of Parkinson's disease (PD), dopaminergic treatment is ineffective for treating postural instability. Recent reports have shown that somatosensory deficit is associated with postural instability, and that somatosensory input improved postural instability. The purpose of this study is to evaluate the effects of lateral wedges for quiet standing postural control in people with PD. Methods: Twenty-two patients who were diagnosed with PD were enrolled in this study. The participants stood on a force plate under two conditions (wedge and no wedge) with or without having their eyes open or closed. The center of pressure (COP) range and velocity were analyzed using a two-way repeated-measures analysis of variance. Results: The range and velocity of COP in the anterioposterior and mediolateral (ML) directions were significantly improved after the patients stood on the lateral wedge with their eyes closed (p < 0.05). The range in ML direction and velocity in both directions of COP were significantly decreased when their eyes were open (p < 0.05). Conclusions: Regardless of vision, standing on lateral wedges improved postural sway in people with PD.

• 의료ㆍ복지 건축 : 한국의료복지건축학회 논문집
• /
• 제15권1호
• /
• pp.23-32
• /
• 2009

Among welfare facilities for the elderly, necessity for the elderly welfare with diverse advantages is rising in the Small-scale Elderly Care Facilities. The government is expecting great demand in the future. However, current the Facilities lack construction plans that consider characteristics of the elderly. Accordingly, 14 case facilities located in JeollaNamdo and Gwangju were selected to comprehensively analyze the circulation of seniors at care facilities by computing spatial depth and visible area variables. As a result of this study, average spatial depth of bathroom, resting room, physical therapy room and dining hall that seniors frequently get in contact with was found to be deep, but visible area appropriate for the function of space was not available. It showed that the circulation for the elderly was deep spatially and long physically, and the spatial rank along circulation which is perceived visually by the admitted the elderly was clear, thus, providing them abundant visual experience supported by high openness as they move from private space to public space. The obtained visibility, however, was observed not to be matched with the function of each space. Since the Small-scale Elderly Care Facilities require various spaces within small surface area, actual functions of each space must be taken into consideration with hierarchical space organization to obtain an environment that stimulates senses such as vision and hearing. In addition, since the circulation of seniors using facilities must consider aging characteristics and delicate care on spatial depth and physical distances, in-depth studies on planning of the circulation in care facilities are deemed necessary.

• 한국산학기술학회논문지
• /
• 제20권6호
• /
• pp.150-157
• /
• 2019

본 연구의 목적은 장딴지근 길이가 동적 균형과 발의 앞뒤 압력분포에 어떤 영향을 미치는지 알아보는 것이다. 연구기간은 2018년 12월 3일부터 21일까지로 30명의 연구대상자를 장딴지근 길이 검사를 통해 장딴지근의 정상길이를 가진 대조군과 장딴지근 길이의 단축이 있는 실험군으로 분류하였다. 동적 균형과 발의 앞뒤 압력분포는 Biorescue장비를 사용하여 평가하였으며 동적 균형을 평가하기 위해 앞쪽과 뒤쪽 방향의 안정성 한계를 데이터로 수집하였다. 군간 동적 균형과 발의 앞뒤 압력분포에 유의한 차이가 있는지 알아보기 위하여 독립 t 검정을 이용하여 분석하였고, 통계학적 유의수준은 0.05로 하였다. 연구 결과 군간 동적 균형과 발의 앞뒤 압력분포는 유의한 차이가 있었다(p<0.05). 이러한 연구 결과를 통해 장딴지근 길이의 단축은 앞쪽으로 동적 균형 및 발의 앞쪽 압력 분포에 영향을 미친다는 것을 제안하고 그러므로 근골격계 질환 예방과 정상적인 균형능력을 위해 장딴지근의 적절한 길이를 유지하는 것은 중요하다.

• 한국융합학회논문지
• /
• 제12권2호
• /
• pp.113-120
• /
• 2021

본 연구는 시각적인 장애를 호소하는 ADHD로 진단받은 아동의 유형별 시각 기능의 특징을 확인하고자 하였다. 연구 대상자는 ADHD로 진단받은 아동 49명으로 시각기능이 정상범위에서 벗어난 경우이다. Korean-ADHD Rating Scale을 이용하여 ADHD 유형을 알아보았고 시각기능 검사를 통해 시각 기능의 문제를 알아보았다. 시각의 문제를 가지고 있는 ADHD 아동들은 부주의 유형(69.4%)이 가장 많았으며 시력은 좋지만 시각 기능 문제가 드러난 경우도 50% 정도 되었다. 주의력결핍 유형에서 근시 관련 시각장애, 과잉활동형 유형에서 난시 관련된 시각장애가 높게 나타났다. 버전스 기능 장애에서는 폭주부족이 가장 많았으며 유형별 차이는 나타나지 않았다. ADHD 아동의 유형별 시각장애의 특성은 차이가 나타나므로 시각 기능 장애의 검사와 선별을 통해 아동의 문제행동에 접근하는 것이 필요하다.

• 영미문화
• /
• 제14권1호
• /
• pp.73-94
• /
• 2014

Accounts from therapeutic culture seem often to associate the selfish, or at least self-centered quest for self-fulfillment with individual choice or satisfaction, self-expression, expressive individualism, and emotionalism. These associations point to the downside of therapy as they present it as constituting a culture of narcissism, selfishness, or irresponsibility. While some of these characterizations contain useful insights, they overlook what are maybe some of the most important features of a therapeutic outlook. This paper aims to reveal that the therapeutic imperative is not so much geared towards the realization of self-fulfillment, as it is the promotion of self-limitation. Therapeutic culture tends to posit the self in a fragile and feeble form and insist that the management of life requires the continuous intervention of therapeutic expertise. Because of this, the elevated concern with the self is underpinned by anxiety, pain, suffering, and survival, rather than seen as a positive vision of realizing the human potential. Therapeutic culture has in this way helped to construct a diminished sense of self by which one is seen as suffering from an emotional deficit and vulnerability. This paper demonstrates this downside of therapeutic culture concerning self-limitation and the sense of a diminished self by examining popular "misery memoirs." Misery memoirs are widely consumed by the general public, therefore tend to be treated by contemporary therapeutic culture as a gospel on the therapeutic ideal for self-fulfillment and self-discovery. This is, despite the existence of hidden evidence to the contrary, because of their redemptive, happy endings that show individuals overcoming difficult trials such as child abuse, incestuous rape, and domestic violence. Individual self-fulfillment and self-discovery in such stories are not achieved through the active agency of the subject but through the passive endurance of pathological symptoms and with the aid of expertise and outside support. Therefore, such stories put victims in the limited position.

• 한국엔터테인먼트산업학회논문지
• /
• 제14권8호
• /
• pp.391-396
• /
• 2020

본 연구는 하지 사슬운동 유형이 라이프케어먼트를 위한 운동 수행능력에 미치는 영향을 알아보고자 하였다. 이를 위해 전라북도 소재 J대학의 정상 성인 여성 20명이 참여하여 두 가지 유형의 사슬운동을 적용하여 배곧은근의 활성도와 균형 능력에 대한 운동 효과 차이를 검사하였다. 참여자들은 각 유형의 운동에 대해 4주 동안 운동을 시행하도록 하였고 그룹 내 및 그룹 간 차이를 비교하기 위해 대응표본 t-검정과 독립 표본 t- 검정을 이용해 분석하였다. 연구 결과, 근육활성도와 균형 기능에서 닫힌사슬 운동이 열린사슬 운동보다 더 효과적이라는 것을 알 수 있었다. 따라서 임상 치료 환경에서 환자에게 하지 운동기능 향상을 위해 사슬운동을 적용할 경우에 닫힌사슬 운동 적용이 보다 효과적일 수 있음을 제시한다.