• Title/Summary/Keyword: Verification and validation

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Validity and Reliability of Korean Version of Post-traumatic Stress Disorder Scale (K-PTSD) Measuring Attitudes and Knowledge of PTSD (한국판 외상 후 스트레스 장애에 대한 태도와 지식 측정도구(K-PTSD)의 타당도와 신뢰도)

  • Bang, Kyung-sook;Bang, Hwal Lan;Hong, Sun-Woo;Lim, Jihee
    • The Journal of Korean Academic Society of Nursing Education
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    • v.26 no.1
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    • pp.47-55
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    • 2020
  • Purpose: The aim of this study was to examine the validity and reliability of the Korean version of the PTSD scale (K-PTSD) for measuring attitudes and knowledge of PTSD. Methods: A cross-sectional study design was used. The K-PTSD scale consisted of 8 items for attitudes, 8 items for general knowledge of PTSD, and 3 items for knowledge of PTSD treatment; 211 nursing students and paramedic students participated. Content validity, item analysis, and factor analysis were used to examine the construct validity. Criterion validity was tested by using educational experience with PTSD as a criterion. Cronbach's α was used to identify internal consistency reliability in the attitude scale. Results: Construct validity of the K-PTSD was verified by exploratory factor analysis, with factor loadings for attitude ranging from .59 to .84. Criterion validity in comparing knowledge of PTSD (t=2.02, p=.044) and PTSD treatment (t=3.19, p=.022) showed a significant difference according to PTSD educational experience. Cronbach's α for the attitude scale was .79 and .59. Conclusion: The findings suggest that the K-PTSD is a valid and reliable tool that can measure attitudes and knowledge of PTSD among nursing and paramedic students. However, further study is needed to retest the verification of this scale with more diverse participants.

Classification of Red Wines by Near Infrared Transflectance Spectroscopy

  • W.Guggenbichler;Huck, C.W.;M.Popp;G.K.Bonn
    • Proceedings of the Korean Society of Near Infrared Spectroscopy Conference
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    • 2001.06a
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    • pp.1516-1516
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    • 2001
  • During the recent years, wine analysis has played an increasing role due the health benefits of phenolic ingredients in red wine [1]. On the other hand there is the need to be able to distinguish between different wine varieties. Consumers want to know if a wine is an adulterated one or if it is based on the pure grape. Producers need to certificate their wines in order to ensure compliance with legal regulations. Up to now, the attempts to investigate the origin of wines were based on high-performance liquid chromatography (HPLC), gas chromatography (GC) and pyrolysis mass spectrometry (PMS) [l,2,3]. These methods need sample pretreatment, long analysis times and therefore lack of high sample throughput. In contradiction to these techniques using near infrared spectroscopy (NIRS), no sample pretreatment is necessary and the analysis time for one sample is only about 10 seconds. Hence, a near infrared spectroscopic method is presented that allows a fast classification of wine varieties in bottled red wines. For this, the spectra of 50 bottles of Cabernet Sauvignon, Lagrein and Sangiovese (Chianti) were recorded without any sample pretreatment over a wavelength range from 1000 to 2500 nm with a resolution of 12 cm$\^$-1/. 10 scans were used for an average spectrum. In order to yield best reproducibility, wines were thermostated at 23$^{\circ}C$ and a optical layer thickness of 3 mm was used. All recorded spectra were partitioned into a calibration and validation set (70% and 30%). Finally, a 3d scatter plot of the different investigated varieties allowed to distinguish between Cabernet Sauvignon, Lagrein and Sangiovese (Chianti). Considering the short analysis times this NRS-method will be an interesting tool for the quality control of wine verification and also for experienced sommeliers.

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Structural evaluation of degradation products of Loteprednol using LC-MS/MS: Development of an HPLC method for analyzing process-related impurities of Loteprednol

  • Rajesh Varma Bhupatiraju;Bikshal Babu Kasimala;Lavanya Nagamalla;Fathima Sayed
    • Analytical Science and Technology
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    • v.37 no.2
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    • pp.98-113
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    • 2024
  • The current investigation entails the characterization of five degradation products (DPs) formed under different stress conditions of loteprednol using liquid chromatography-tandem mass spectrometry (LC-MS/MS). In addition, this study developed a stable high-performance liquid chromatography (HPLC) method for evaluating loteprednol along with impurities. The method conditions were meticulously fine-tuned which involved the exploration of the appropriate solvent, pH, flow of the mobile phase, columns, and wavelength. The method conditions were carefully chosen to successfully resolve the impurities of loteprednol and were employed in subsequent validation procedures. The stability profile of loteprednol was exposed to stress degradation experiments conducted under five conditions, and DPs were structurally characterized by employing LC-MS/MS. The chromatographic resolution of loteprednol and its impurities along with DPs was effectively achieved using a Phenomenex Luna 250 mm C18 column using 0.1 % phosphoric acid, methanol, and acetonitrile in 45:25:30 (v/v) pumped isocratically at 0.8 mL/min with 243 nm wavelength. The method produces an accurate fit calibration curve in 50-300 ㎍/mL for loteprednol and LOQ (0.05 ㎍/mL) - 0.30 ㎍/mL for its impurities with acceptable precision, accuracy, and recovery. The stress-induced degradation study revealed the degradation of loteprednol under basic, acidic, and photolytic conditions, resulting in the formation of seven distinct DPs. The efficacy of this method was validated through LC-MS/MS, which allowed for the verification of the chemical structures of the newly generated DPs of loteprednol. This method was appropriate for assessing the impurities of loteprednol and can also be appropriate for structural and quantitative assessment of its degradation products.

Development and Validation of Primary Method for the Determination of Glucose in Human Serum by Isotope Dilution Liquid Chromatography Tandem Mass Spectrometry and Comparison with Field Methods

  • Lee, Hwa Shim;Lee, Jong Man;Park, Sang Ryoul;Lee, Je Hoon;Kim, Yong Goo
    • Bulletin of the Korean Chemical Society
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    • v.34 no.6
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    • pp.1698-1702
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    • 2013
  • Glucose is a common medical analyte measuring in human serum or blood samples. The development of a primary method is necessary for the establishment of traceability in measurements. We have developed an isotope dilution liquid chromatography tandem mass spectrometry as a primary method for the measurement of glucose in human serum. Glucose and glucose-$^{13}C_6$ in sample were ionized in ESI negative mode and monitored at mass transfers of m/z 179/89 and 185/92 in MRM, respectively. Glucose was separated on $NH_2P$-50 2D column, and the mobile phase was 20 mM $NH_4OAc$ in 30% acetonitrile/70% water. Verification of this method was performed by the comparison with NIST SRMs. Our results agreed well with the SRM values. We have developed two levels of glucose serum certified reference material using this method and distributed them to the clinical laboratories in Korea as samples for proficiency testings. The expended uncertainty was about 1.2% on 95% confidence level. In proficiency testings, the results obtained from the clinical laboratories showed about 3.6% and 3.9% RSD to the certified values. Primary method can provide the traceability to the field laboratories through proficiency testings or certified reference materials.

Cloning of Korean Morphological Analyzers using Pre-analyzed Eojeol Dictionary and Syllable-based Probabilistic Model (기분석 어절 사전과 음절 단위의 확률 모델을 이용한 한국어 형태소 분석기 복제)

  • Shim, Kwangseob
    • KIISE Transactions on Computing Practices
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    • v.22 no.3
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    • pp.119-126
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    • 2016
  • In this study, we verified the feasibility of a Korean morphological analyzer that uses a pre-analyzed Eojeol dictionary and syllable-based probabilistic model. For the verification, MACH and KLT2000, Korean morphological analyzers, were cloned with a pre-analyzed eojeol dictionary and syllable-based probabilistic model. The analysis results were compared between the cloned morphological analyzer, MACH, and KLT2000. The 10 million Eojeol Sejong corpus was segmented into 10 sets for cross-validation. The 10-fold cross-validated precision and recall for cloned MACH and KLT2000 were 97.16%, 98.31% and 96.80%, 99.03%, respectively. Analysis speed of a cloned MACH was 308,000 Eojeols per second, and the speed of a cloned KLT2000 was 436,000 Eojeols per second. The experimental results indicated that a Korean morphological analyzer that uses a pre-analyzed eojeol dictionary and syllable-based probabilistic model could be used in practical applications.

A study of the Investigation Offices' Planning Standard and Criteria of the Police Station - By Analyzing the Actual Situation Survey of the Prototypes - (경찰서 수사부서 표준설계 공간모형과 지침 연구 - 환경개선 시범사례 실태조사를 중심으로 -)

  • Cho, Hyeonmi
    • Korean Institute of Interior Design Journal
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    • v.27 no.1
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    • pp.140-155
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    • 2018
  • In response to the development of IT technology in the 21st century and the advancement of the public human rights consciousness, it has become necessary to continuously evolve the office environments to support the changes of organizational structure and work methods of the police investigation departments. As a facility standard, continuous researches on standardized design space models and guidelines of the police investigation departments are needed. In respond to the organizational changes for the convenience of the working police investigators and the protection of the human rights of the visiting public, the environmental improvement projects for the office of the investigation department of the police stations are going on since 2014. In this study, analyzation and verification of the 3 cases of pilot projects for the improvement of police investigation departments would be done, based on the policy research project in 2014: 'the standard design direction of police officers for the protection of human rights and benefit of police investigation process.' The purpose of this study is, first of all, the actual situation survey for presenting the standard design space model and guidelines of investigation department of the police department. Secondly, the validation of the spatial model adequacy for for the past 3 years' case study of the police investigation department's environmental improvements by the application of standardized design space models and guidelines. The result of this study would be to enable the more effective police department investigation environment improvement policy by presenting the standard design space models and guidelines of the investigation departments of the police facilities.

NuSEE: AN INTEGRATED ENVIRONMENT OF SOFTWARE SPECIFICATION AND V&V FOR PLC BASED SAFETYCRITICAL SYSTEMS

  • Koo, Seo-Ryong;Seong, Poong-Hyun;Yoo, Jun-Beom;Cha, Sung-Deok;Youn, Cheong;Han, Hyun-Chul
    • Nuclear Engineering and Technology
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    • v.38 no.3
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    • pp.259-276
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    • 2006
  • As the use of digital systems becomes more prevalent, adequate techniques for software specification and analysis have become increasingly important in nuclear power plant (NPP) safety-critical systems. Additionally, the importance of software verification and validation (V&V) based on adequate specification has received greater emphasis in view of improving software quality. For thorough V&V of safety-critical systems, V&V should be performed throughout the software lifecycle. However, systematic V&V is difficult as it involves many manual-oriented tasks. Tool support is needed in order to more conveniently perform software V&V. In response, we developed four kinds of computer aided software engineering (CASE) tools to support system specification for a formal-based analysis according to the software lifecycle. In this work, we achieved optimized integration of each tool. The toolset, NuSEE, is an integrated environment for software specification and V&V for PLC based safety-critical systems. In accordance with the software lifecycle, NuSEE consists of NuSISRT for the concept phase, NuSRS for the requirements phase, NuSDS for the design phase and NuSCM for configuration management. It is believed that after further development our integrated environment will be a unique and promising software specification and analysis toolset that will support the entire software lifecycle for the development of PLC based NPP safety-critical systems.

Construction of the Regional Prediction System using a Regional Climate Model and Validation of its Wintertime Forecast (지역기후모델을 이용한 상세계절예측시스템 구축 및 겨울철 예측성 검증)

  • Kim, Moon-Hyun;Kang, Hyun-Suk;Byun, Young-Hwa;Park, Suhee;Kwon, Won-Tae
    • Atmosphere
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    • v.21 no.1
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    • pp.17-33
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    • 2011
  • A dynamical downscaling system for seasonal forecast has been constructed based on a regional climate model, and its predictability was investigated for 10 years' wintertime (December-January-February; DJF) climatology in East Asia. Initial and lateral boundary conditions were obtained from the operational seasonal forecasting data, which are realtime output of the Global Data Assimilation and Prediction System (GDAPS) at Korea Meteorological Administration (KMA). Sea surface temperature was also obtained from the operational forecasts, i.e., KMA El-Nino and Global Sea Surface Temperature Forecast System. In order to determine the better configuration of the regional climate model for East Asian regions, two sensitivity experiments were carried out for one winter season (97/98 DJF): One is for the topography blending and the other is for the cumulus parameterization scheme. After determining the proper configuration, the predictability of the regional forecasting system was validated with respect to 850 hPa temperature and precipitation. The results showed that mean fields error and other verification statistics were generally decreased compared to GDAPS, most evident in 500 hPa geopotential heights. These improved simulation affected season prediction, and then HSS was better 36% and 11% about 850 hPa temperature and precipitation, respectively.

The Effects of Coding Education Using the Unplugged Robot Education System on the Perceived Useful and Easy

  • Song, JeongBeom
    • Journal of the Korea Society of Computer and Information
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    • v.20 no.8
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    • pp.121-128
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    • 2015
  • This study aimed to investigate the effects of an unplugged robot education system capable of computerless coding education. Specifically, this study compared this education system with PicoCricket, an educational robot that can also be used with elementary students in lower grades, using assessment tools on perceived usefulness and ease. Using random sampling and randomized assignment for more objective validation, 30 participants were assigned to the unplugged robot education system group (experimental group) and 30 participants were assigned to the PicoCricket group (control group), for a total of 60 study participants. The research procedure included verification of the equivalence of the two groups by conducting a pretest after a 2-hour basic training session on algorithms and programming. The experimental and control groups learned the same content using different educational tools in accordance with software training guidelines for a total of 12 hours. Then, the difference in perceived usefulness and ease between the two groups was examined using a post-treatment test. The study results showed that scores on both dependent variables, perceived usefulness and perceived ease, were significantly higher in the experimental group than the control group. Moreover, scores on all sub-variables of the dependent variables were significantly higher in the experimental group than the control group. These results suggest that learners using the unplugged robot education system found it more useful and easier to use than learners using the existing educational robot, PicoCricket. This study's findings are significant, as according to the technology acceptance model, the perceived usefulness and ease of an educational tool are important variables that determine the acceptance of the tool (i.e., persistence of learning).

The Complementary Study for Operational Concept Document(OCD) and Operational Requirements Document(ORD) using MND-AF (MND-AF를 활용한 운용개념기술서(OCD) 및 운용요구서(ORD)에 대한 보완 연구)

  • Cha, Seung Hun;Jang, Jae Duck;Lee, Hye Jin;Choi, Sang Wook;Yoo, Jae Sang
    • Journal of the Korean Society of Systems Engineering
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    • v.16 no.2
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    • pp.118-130
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    • 2020
  • Modern weapon systems are composed of complex systems(System of Systems) and require a complex and advanced operational concept that performs missions through interoperability with various weapon systems. In order to derive the operational concept of the weapon system that the military wants to acquire (i.e., single mission, component operation, Joint and Alliance operations), it is necessary to identify the system related to the weapon system, environmental factors and restrictions of the weapon system to be developed. Through the derivation of the operational concept, the weapon system acquisition agency can reasonably and accurately extract various and complex requirements. In this paper, we propose a complementary method of using MND-AF to OCD and ORD required in weapon system acquisition process. MND-AF can increase the understanding and consensus of business stakeholders (users, acquirers, developers, etc.) by showing the results of weapon system analysis from various perspectives. We compare the items in the standard form of OCD and ORD with the MND-AF outputs.