• Title/Summary/Keyword: Ventilation rates

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Clinical Manifestations and Outcomes of Older Patients with COVID-19: A Comprehensive Review

  • Jeong Eun Lee;Da Hyun Kang;So-Yun Kim;Duk Ki Kim;Song I Lee
    • Tuberculosis and Respiratory Diseases
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    • v.87 no.2
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    • pp.145-154
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    • 2024
  • The consequences of coronavirus disease 2019 (COVID-19) are particularly severe in older adults with a disproportionate number of severe and fatal outcomes. Therefore, this integrative review aimed to provide a comprehensive overview of the clinical characteristics, management approaches, and prognosis of older patients diagnosed with COVID-19. Common clinical presentations in older patients include fever, cough, and dyspnea. Additionally, preexisting comorbidities, especially diabetes and pulmonary and cardiovascular diseases, were frequently observed and associated with adverse outcomes. Management strategies varied, however, early diagnosis, vigilant monitoring, and multidisciplinary care were identified as key factors for enhancing patient outcomes. Nonetheless, the prognosis remains guarded for older patients, with increased rates of hospitalization, mechanical ventilation, and mortality. However, timely therapeutic interventions, especially antiviral and supportive treatments, have demonstrated some efficacy in mitigating the severe consequences in this age group. In conclusion, while older adults remain highly susceptible to severe outcomes from COVID-19, early intervention, rigorous monitoring, and comprehensive care can play a pivotal role in improving their clinical outcomes.

Single or Dual Infection with Respiratory Syncytial Virus and Human Rhinovirus: Epidemiology and Clinical Characteristics in Hospitalized Children in a Rural Area of South Korea (호흡기세포융합바이러스와 라이노바이러스의 단독 혹은 동시감염의 역학 및 임상적 특성: 강원 지역 단일 기관의 후향적 연구)

  • Kwon, Yerim;Cho, Won Je;Kim, Hwang Min;Lee, Jeongmin
    • Pediatric Infection and Vaccine
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    • v.26 no.2
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    • pp.99-111
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    • 2019
  • Purpose: Respiratory syncytial virus (RSV) and human rhinovirus (hRV) are the most common causes of child respiratory viral infections. We aimed to investigate epidemiological and clinical characteristics of RSV and hRV single infections and coinfections. Methods: Nasopharyngeal aspirates of hospitalized children aged <5 years were tested using multiplex reverse transcription polymerase chain reaction (RT-PCR) from October 2014 to April 2017. Their medical records were retrospectively reviewed. Results: RSV or hRV was detected in 384 patients who divided into 3 groups: patients with RSV (R group, n=258); patients with hRV (H group, n=99); and patients with both (RH group, n=27). The R group (median age, 6 months) consisted of 248 (96.1%) patients with lower respiratory tract infection (LRTI), and 14 (5.4%) needed oxygen inhalation. Infants aged <12 months (63.2%) had respiratory difficulty and were supplied oxygen more often. The H group (median age, 16 months) consisted of 56 (56.6%) patients with LRTI, 4 (4%) required oxygen inhalation, and 1 (1.0%) required mechanical ventilation. Infants (40.4%) showed longer hospitalization compared to patients aged ${\geq}12$ months (5 vs. 4 days, P<0.05). The RH group consisted of 24 (88.9%) patients with LRTI, and 2 (7.4%) needed oxygen inhalation. Hospitalization days and oxygen inhalation and mechanical ventilation rates did not differ between single infections (R and H groups) and coinfections (RH group). Conclusions: RSV was detected more often in younger patients and showed higher LRTI rates compared to hRV. Single infections and coinfections of RSV and hRV showed no difference in severity.

Effects of Tropical Climate on Reproduction of Cross- and Purebred Friesian Cattle in Northern Thailand

  • Pongpiachan, P.;Rodtian, P.;Ota, K.
    • Asian-Australasian Journal of Animal Sciences
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    • v.16 no.7
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    • pp.952-961
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    • 2003
  • In the first part of the study, rates of estrus occurrence and success of A.I. service in the Thai-native and Friesian crossbred, and purebred Friesian cows fed in the National Dairy Training and Applied Research Institute in Chiang Mai, Thailand were traced monthly throughout a year. An electric fan and a water sprinkler cooled the stall for the purebred cows during the hot season (March-September). Both rates in pure Friesians were at their highest in the cold-dry season (October- February), but they decreased steadily during the hot-dry season (March-May) and were at their lowest in the hot-wet season (June-September). Seasonal change of a similar pattern was observed in the incidence of estrus, but not in the success rate of insemination in the crossbred cows. By the use of reproductive data, compiled in the same institute, on the 75 % cross- and purebred Friesian cows, and climatological data in Chiang Mai district, effects of ambient temperature and humidity on the reproductive traits of cows were examined by regression analysis in the second half of the study. Significant relationships in the crossbred, expressed by positive-linear and parabola regressions, were found between reproductive parameters such as days to the first estrus (DTFE), A.I. service (DTFAI), and conception, the number of A.I. services required for conception and some climatic factors. However, regarding this, no consistent or intelligible results were obtained in purebred cows, perhaps because electric fans and water sprinklers were used for this breed in the hot season. Among climatic factors examined, the minimum temperature (MINT) in early lactation affected reproductive activity most conspicuously. As the temperature during one or two months prior to the first estrus and A.I. service rose, DTFE and DTFAI steadily became longer, although, when MINT depleted below $17-18^{\circ}C$, the reproductive interval tended to be prolonged again on some occasions. The maximum temperature also affected DTFE and DTFAI, but only in limited conditions. The effect of humidity was not clear, although the inverse relationship between DTFE and minimum humidity during 2 months before the first estrus in the crossbred seemed to be significant. Failure to detect any definite effect of climate on the reproductive traits of pure Friesians seemed to indicate that forced ventilation by electric fans and water sprinklers were effective enough to protect the reproductive ability of this breed from the adverse effects of a hot climate.

Performance for a small on-site wastewater treatment system using the absorbent biofilter in rural areas (흡수성 Biofilter 를 이용한 농촌 소규모 오수처리 시설의 성능)

  • Kwun, Soon-Kuk;Yoon, Chun-Gyeong
    • Korean Journal of Environmental Agriculture
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    • v.18 no.4
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    • pp.310-315
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    • 1999
  • The feasibility of an absorbent biofilter system was examined for rural wastewater treatment. Hydraulic loading rates varied from 50 to 250 cm/day. Effluent of the septic tank was fed into the absorbent biofilter, and small ventilation fan was provided to supply air at the rate of 250 L/min to aerate the biofilter. The biofilter system demonstrated high removal rates for $BOD_5$ and TSS at the loading rate of 150 cm/day, generally meeting the Korean effluent water quality standard of 20 mg/L applicable to both. The nutrient removal was less satisfactory than the results of $BOD_5$ and TSS, but it was within the expected range of biological treatment processes. Considering the abnormally high influent concentration of nutrients during the experiment, better performance results could have been obtained if ordinary domestic wastewater was used. The system performance was not significantly affected by the hydraulic loading up to 150 cm/day, which is far more than the loading limit of the sand filter systems. Maintenance requirement was minimal, and no problems with noise, odor, flies or sludge arose. Since the biofilter system can be operated at a distance, operation in remote rural area and multi-system connected to one control office might be advantageous to the rural area. Overall, considering the cost-effectiveness, stable performance, and minimum maintenance, the biofilter system was thought to be a competitive alternative to treat wastewater in Korean rural communities.

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Separate type heat pipe performance comparison by the heat exchanger shapes (열교환기 형상에 따른 분리형 히트파이프 성능 비교)

  • Jeon, Sung-Taek;Cho, Jin-Pyo
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.17 no.12
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    • pp.723-729
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    • 2016
  • This study compared fin-tube and parallel-flow heat pipes for their sensible heat exchange rate, heat recovery amount, and air-side pressure drop. Tests were done with different refrigerant charging rates of 40-60% vol. and air flow rates of 300-1,400. The sensible heat exchange rate was highest for both types of heat pipes at a working fluid charge of 40% vol. and low flow rate. For the parallel-flow heat pipe, the 60% vol. charge is too high and results in a low sensible heat exchange rate. The reason is that the thicker liquid film of the tube wall deteriorates the heat transfer effect. Hence, the optimal charging rate is 40 to 50% vol. The evaporator heat pipe has a larger air-side pressure drop than the condenser section heat pipe. The reason is considered to be condensation water arising from the evaporator surface. Compared to the fin-tube heat pipe, the parallel-flow heat pipe showed better performance with a working fluid charging rate of 48%, volume of 41%, and an air-side pressure drop about 37%.

Changes of Heart Rate During Marathon Running (장거리 (마라톤)선수에서의 전 경기중 심박동수의 변화)

  • Kim, In-Kyo;Lee, Jung-Woo;Hah, Jong-Sik;Ryu, Yun-Hee;Choi, Jung-Ok;Kim, Ki-Ho
    • The Korean Journal of Physiology
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    • v.13 no.1_2
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    • pp.1-12
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    • 1979
  • To evaluate the present status of physical fittness of Korean long distance runners, body fat, pulmonary functions, maximal oxygen intake and oxygen debt were measured in 5 elite marathoners (A group), 6 college student runners (B group) and 3 middle school student runners (C group). After laboratory tests, full course marathon running was performed in 2 elite marathoners during which their heart rates were monitored continuously. The results are summerized as follows: 1) Total body fat in all three groups are in the range of 13-15% of their body weight. 2) In all three groups, average values of various pulmonary functions were within the normal limits, but those of tidal volume were higher and respiratory rate were lower in comparison to normal values. These phenomena may represent respiratory adaptations against training. The average resting oxygen consumptions in A,B and C were $322{\pm}23$, $278{\pm}14$ and $287{\pm}16$m1/min, respectively. 3) In all three groups, resting blood pressures were in the normal range, but the resting heart rate was slightly lower in groups A $(56{\pm}3\;beats/min)$ and B $(64{\pm}2\;beats/min)$ and higher in group C $(82{\pm}9\;beats/min)$ in comparison to normal values. These changes in cardiovascular functions in marathoners may also represent adaptive phenomena. 4) During treadmill running the minute ventilation and oxygen consumption of the runners increased lineally with work load in all three groups. When the oxygen consumption was related to heart rate, it appeared to be a exponential function of the heart rate in all three groups. 5) The average maximal heart rates during maximal work were $196{\pm}3$, $191{\pm}3$ and $196{\pm}5\;beats/min$ for groups A,B and C, respectively. Maximal oxygen intakes were $84.2{\pm}3.3\;ml/min/kg$ in group A, $65.2{\pm}1.1\;ml/min/kg$ in group B and $58.7{\pm}0.4\;ml/min/kg$ in group C. 6) In all three groups, oxygen debts and the rates of recovery of heart rate after treadmill running were lower than those of long ditsance runners reported previously. 7) The 40 km running time in 2 elite marathoners was recorded to be $2^{\circ}42'25'$, and their mean speed was 243 m/min (ranged 218 to 274 m/min). The heart rate appeared to increase lineally with running speed, and the total energy expenditure during 40 km running was approximately 1360.2 Calories. From these it can be speculated that if their heart rates were maintained at 166 beats/min during the full course of marathon running, their records would be arround $2^{\circ}15'$. Based on these results, we may suspect that a successful long distance running is, in part, dependent on the economical utilization of one's aerobic capacity.

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Safety and Significance of Surgical Lung Biopsy for Interstitial Lung Disease (간질성 폐질환에 대한 수술적 폐생검의 의의 및 안전성)

  • Lee, Yu Jin;Joung, Mi Kyong;Chung, Chae Uk;Park, Ji Won;Shin, Ji Young;Jung, Sun Young;Lee, Jeong Eun;Park, Hee Sun;Jung, Sung Soo;Kim, Ju Ock;Kim, Sun Young
    • Tuberculosis and Respiratory Diseases
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    • v.63 no.1
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    • pp.59-66
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    • 2007
  • Background: Surgical lung biopsy is required to establish the etiology and stage of interstitial lung disease(ILD). and this procedure can be safe and meaningful for making clinical decisions. We wanted to determine the safety of surgical lung biopsy(SLB) in patients with interstitial lung disease(ILD). Methods: We conducted a retrospective review of 40 patients with suspected ILD and they underwent surgical lung biopsy from January 2001 to June 2006 at Chungnam University Hospital. We analyzed retrospectively according to their age, gender, pulmonary function, chest tube duration, the arterial blood gases, the procedural technique, and the requirement for supplemental oxygen and mechanical ventilation(MV) at the time of SLB. Results: The mean age of the patients was 56.4${\pm}$16.13 years(range: 21 to 77 years). Overall, the 30-day and 90-day mortality rates were 15% and 20%, respectively. The predictors of perioperative mortality were either the need for mechanical ventilation(MV) at the time of SLB or the need for supplemental oxygen prior to undergoing SLB. Among the 32 patients who were 90-day survivors, the proportion of those patients using the oxygen supplement was 28.1% (n=9). All 8 patients who were 90-day non-survivors used oxygen supplement (p=0.000). The use of the MV was 12.5% (n=4) in the 90-day survivors (n=32) and 62.5% (n=5) in the 90-day non-survivors (n=8); there was a significant difference between the 90-day survivors and non-survivors (p=0.000). Conclusion: Patients who require MV and supplemental oxygen are associated with an increased risk for death following SLB.

Survey and model development of the mechanization for swine farming (양돈농가의 기계화 실태분석 및 모델개발)

  • 이성현;박원규;강창호;오권영
    • Journal of Bio-Environment Control
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    • v.7 no.2
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    • pp.91-108
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    • 1998
  • This study was carried out to survey basic information of swine farms on the machine holdings. facility type. management of manure by farm scale and operation, and then to develop the mechanization model. Manual feeding was common for sows and nursing sows. but automation feeding was normally furnished for weaners. growing pigs and castrated male pigs. Water supplies was completely automated for all of the surveyed swine farms. Fully mechanized and automated system would not be feasible and affordable for the small scale farms breeding less than 500 heads. Because the environmental control for the nursing sows and weaner was important, some swine houses were constructed with the windowless type. However, the furnished rates ranged from 22.2% to 44.4% of the surveyed nursing sow and weaner houses at the farm scales. In the future, a computerized ventilation system would be commended for the efficient use of heat energy and to maintain the desirable temperature of swine buildings. Over-investment for large scale farm and over-crowded pigpen of small farm would cause wasting construction expenses and spreading epidermic diseases Hence, the size of swine building should follow the recommended scale. The fermentation drier was recommended for the manure management. Urine could be recycled or discharged after treating by the activated sludge process.

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Assessment of VOCs Emission Characteristics from Building Materials such as Wall Paper, Paints, and Adhesives Using Small Chamber Method (소형챔버법을 이용한 건축자재 중 벽지, 페인트 및 접착제의 VOCs 방출특성 평가)

  • Lee Suk-Jo;Jang Seong-Ki;Cho Yong-Sung;Jung Kyung- Mi;Jeong Gi-Ho
    • Journal of Korean Society for Atmospheric Environment
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    • v.21 no.2
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    • pp.191-204
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    • 2005
  • Building and furnishing materials and consumer product are important sources of volatile organic compounds(VOCs) and other aldehydes in the indoor environment. Some available evidence indicates that VOCs can cause adverse health effects to the building occupants and contribute to some of the symptoms of what we call, 'Sick House Syndrome' in Korea. The aims of this study were to evaluate the efficiency of emission system and to investigate comparison of the emission characteristics of different building materials such as wall-papers, paints, and adhesives. The emission of VOCs from building materials were determined in the small chambers defining the temperature, relative humidity, and ventilation rate in this study. VOCs were sampled for 20 minutes using Tenax-TA tubes and analysed by GC-MS with thermal desorption. The stability of conditions for temperature and relative humidity in this small chamber system showed that the fluctuation of temperature was between 25.4$\pm$0.3$^{\circ}C$ and that of relative humidity was 50.2$\pm$0.6$\%$ under the airflow rate of 167 mL/min. The emission tests from building materials resulted in TVOC emission rates of 0.011 $\~$ 3.108 mg/m$^{2}$h after 7 days. The general wall-papers emitted toluene abundantly and the natural wall-papers mainly emitted n-butanol and a minor amount of alkanes compound such as n -tetradecane. The remainder consisted of toluene, m,p -xylene, and styrene. The paints mainly emitted toluene and the adhesives mainly emitted chloroform as well as toluene. As a result, this study is expected to suggest meaningful data for future studies in exposure control through selecting healthy building materials and for the establishment of guidelines for various building materials in Korea.

Effect of Fish Number in Respiratory Chamber on Routine Oxygen Consumption of Black Porgy Acanthopagrus schlegeli Reared in Seawater or Freshwater (해수 및 담수사육 감성돔, Acanthopagrus schlegeli의 호흡측정실내 수용개체수에 따른 산소소비 비교)

  • Jeong, Min-Hwan;Kim, Young-Soo;Min, Byung-Hwa;Chang, Young-Jin
    • Journal of Aquaculture
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    • v.20 no.2
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    • pp.121-126
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    • 2007
  • Comparison of fish number on routine oxygen consumption (OC) of black porgy (Acanthopagrus schlegeli) reared in seawater (SW) versus freshwater (FW) was performed in closed water-recirculating system containing respiratory chamber. Fish acclimated in separate indoor tanks with SW or FW were sampled as two groups (one or three of fish used, $mean\;{\pm}\;S.D.=36.4{\pm}9.8$). OC of fish reared in both SW and FW showed clear temporal rhythms, with higher values in the daytime and lower values at night, in accordance with light (09:00-21:00 h) and dark (21:00-09:00 h) phases of the diel cycle (12L:12D). The OC of the fish increased linearly with the water temperature. The OCs of black porgy reared in SW and FW at 15, 20, $25^{\circ}C$ were 140.0, 174.8, 282.3 mg $O^2{\cdot}kg^{-1}{\cdot}h^{-1}$ and 177.5, 307.8, 413.1 mg $O^2{\cdot}kg^{-1}{\cdot}h^{-1}$ for the one of fish used, and 200.5, 274.7, 339.1 mg $O^2{\cdot}kg^{-1}{\cdot}h^{-1}$ and 118.2, 188.2, 252.8 mg $O^2{\cdot}kg^{-1}{\cdot}h^{-1}$ for three of fish used, respectively. Black porgy reared in SW had higher ventilation rates than those in FW. These results indicate that black porgy reared in FW had higher OC than those in SW at the one of fish used, but the fish reared in SW had higher OC than those in FW at the three of fish used.