• Title/Summary/Keyword: Velocity response

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Association between periodontal bacteria and degenerative aortic stenosis: a pilot study

  • Kataoka, Akihisa;Katagiri, Sayaka;Kawashima, Hideyuki;Nagura, Fukuko;Nara, Yugo;Hioki, Hirofumi;Nakashima, Makoto;Sasaki, Naoki;Hatasa, Masahiro;Maekawa, Shogo;Ohsugi, Yujin;Shiba, Takahiko;Watanabe, Yusuke;Shimokawa, Tomoki;Iwata, Takanori;Kozuma, Ken
    • Journal of Periodontal and Implant Science
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    • v.51 no.4
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    • pp.226-238
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    • 2021
  • Purpose: Although several reports have described the relationship between periodontal disease and cardiovascular disease, information about the association between periodontal disease and the progression of degenerative aortic stenosis (AS) is lacking. Therefore, we performed a retrospective, single-center, pilot study to provide insight into this potential association. Methods: Data from 45 consecutive patients (19 men; median age, 83 years) with mild or moderate degenerative aortic stenosis were analyzed for a mean observation period of 3.3±1.9 years. The total amount of Aggregatibacter actinomycetemcomitans and Porphyromonas gingivalis and titers of serum immunoglobulin G (IgG) against periodontal bacteria and high-sensitivity C-reactive protein (hs-CRP) were evaluated. Aortic valve area (AVA), maximal velocity (Vmax), mean pressure gradient (mean PG), and the Doppler velocity index (DVI) were evaluated. The change in each parameter per year ([ParameterLATEST-ParameterBASELINE]/Follow-up Years) was calculated from the retrospective follow-up echocardiographic data (baseline vs. the most recently collected data [latest]). Results: No correlation was found between the concentration of periodontopathic bacteria in the saliva and AS status/progression. The anti-P. gingivalis antibody titer in the serum showed a significant positive correlation with AVA and DVI. Additionally, there was a negative correlation between the anti-P. gingivalis IgG antibody titer and mean PG. The hs-CRP concentration showed positive correlations with Vmax and mean PG. Meanwhile, a negative correlation was observed between the anti-P. gingivalis IgG antibody titer and ΔAVA/year and Δmean PG/year. The hs-CRP concentration showed positive correlations with Vmax and mean PG, and it was significantly higher in patients with rapid aortic stenosis progression (ΔAVA/year <-0.1) than in their counterparts. Conclusions: Our results suggest that periodontopathic bacteria such as A. actinomycetemcomitans and P. gingivalis are not directly related to the status/progression of degenerative AS. However, inflammation and a lower immune response may be associated with disease progression.

Feasibility Evaluation for Remediation of Groundwater Contaminated with Heavy Metal using Calcium Polysulfide in Homogeneous media (균질한 매질 내 Calcium polysulfide 주입에 따른 고농도 중금속 오염 지하수 정화 타당성 검토)

  • Hyeon Woo Go;Jin Chul Joo;Kyoungphile Nam;Hee Sun Moon;Sung Hee Yoon;Dong Hwi Lee;So Ye Jang
    • Journal of Soil and Groundwater Environment
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    • v.28 no.1
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    • pp.1-14
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    • 2023
  • In this study, column tests using relatively uniform Jumunjin sand media were conducted to evaluate the feasibility of calcium polysulfide (CaSx, CPS) in removing high concentration of Zn2+ in groundwater. The injected CPS solution reacted rapidly with Zn2+ in artificial groundwater and effectively reduced Zn2+ by more than 99% through metal sulfide precipitation. Since the density (d = 1.27 g/cm3 ) of CPS solution was greater than that of water, CPS solution settled down rapidly while capturing Zn2+ and formed stable CPS layer similar to dense nonaqueous phase liquid. Mass balance analysis on Zn2+ in CPS solution suggested that CPS solution effectively reacted with Zn2+ to form metal sulfide precipitates except for high groundwater seepage velocity of 400 cm/d. With greater groundwater seepage velocity, injected CPS did not completely dissolve at the CPS-water interface, but a partially-misible CPS layer continuously moved and reacted with Zn2++ in the direction of groundwater flow. Since hydraulic conductivity (Kh) decreased slightly due to the generated metal precipitates in the inter-pores of media, injection of CPS solution should be optimized to prevent clogging. As evidenced by both XRF and SEM/EDS results, ZnS precipitates were clearly observed through the reaction between the CPS solution and Zn2+. Further study is warranted to evaluate the feasibility of CPS to remove high-concentration heavy metalcontaminated groundwater in complex and heterogeneous media.

Evaluation of the applicability of the surface wave method to rock fill dams (사력댐에서의 표면파 기법 적용성 평가 연구)

  • Kim, Jong-Tae;Kim, Dong-Soo;Park, Heon-Joon;Bang, Eun-Seok;Kim, Sung-Woo
    • Geophysics and Geophysical Exploration
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    • v.13 no.1
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    • pp.9-23
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    • 2010
  • In current design practice, the shear wave velocity (Vs) of the core and rock-fill zone of a dam, one of the characteristics essential for seismic response design, is seldom determined by field tests. This is because the borehole seismic method is often restricted in application, due to stabilisation activities and concern for the security of the dam structure, and surface wave methods are limited by unfavourable in-situ site conditions. Consequently, seismic response design for a dam may be performed using Vs values that are assumed, or empirically determined. To estimate Vs for the core and rock-fill zone, and to find a reliable method for measuring Vs, seismic surface wave methods have been applied on the crest and sloping surface of the existing 'M' dam. Numerical analysis was also performed to verify the applicability of the surface wave method to a rock-fill dam. Through this numerical analysis and comparison with other test results, the applicability of the surface wave method to rock-fill dams was verified.

Analysis of Nocturnal Cold Air Flow Characteristics for Setting of Tropical Night Response Zone in Daegu (대구시 열대야 대응 구역 설정을 위한 야간 찬공기 유동성 분석)

  • SEO, Bo-Yong;LEE, Sang-Beom;GWON, Soon-Beom;CHA, Jae-Gyu;JUNG, Eung-Ho
    • Journal of the Korean Association of Geographic Information Studies
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    • v.23 no.3
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    • pp.220-235
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    • 2020
  • Heat wave generation in cities is basically affected by global warming, but it is further exacerbated by the impact of artificial heat emission and heat accumulation in the city. In particular, the effects of urban heat waves directly affect the occurrence of tropical nights. Basically, however, the choice of countermeasures against tropical nights is very limited compared to the daytime heat wave response. The purpose of this study was to analyze the characteristics of cold air flow at night as a countermeasure against tropical nights in Daegu Metropolitan City and to suggest its spatial applicability. As a research method, the spatial characteristics (flow velocity, flow rate, flow direction and range) of cold air flow in Daegu were quantitatively analyzed using KLAM_21, a cold air flow analysis program. As a result of the analysis, it was found that cold air generation and flow in the surrounding mountains of Daegu Metropolitan City was very active, but the inflow was limited to the urban area, which has tropical nights. However, it has been shown that the flow of cold air flowing from the surrounding mountains is very active in some urban areas, so it has spatial conditions that are very effective in countering tropical nights. If these spatial conditions are used for the urban planning, it will be very useful to develop countermeasures for tropical nights.

Identification of damage states and damge indices of single box tunnel from inelastic seismic analysis (비탄성 지진 해석을 통한 박스 터널의 손상 상태 및 손상 지수 규명)

  • Park, Duhee;Lee, Tae-Hyung;Kim, Hansup;Park, Jeong-Seon
    • Journal of Korean Tunnelling and Underground Space Association
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    • v.18 no.2
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    • pp.119-128
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    • 2016
  • In a performance-based design, the structural safety is estimated from pre-defined damage states and corresponding damage indices. Both damage states and damage indices are well defined for above-ground structures, but very limited studies have been performed on underground structures. In this study, we define the damage states and damage indices of a cut-and-cover box tunnel which is one of typical structures used in metro systems, under a seismic excitation from a series of inelastic frame analyses. Three damage states are defined in terms of the number of plastic hinges that develop within the structure. The damage index is defined as the ratio of the elastic moment to the yield moment. Through use of the proposed index, the inelastic behavior and failure mechanism of box tunnels can be simulated and predicted through elastic analysis. In addition, the damage indices are linked to free-field shear strains. Because the free-field shear strain can be easily calculated from a 1D site response analysis, the proposed method can be readily used in practice. Further studies are needed to determine the range of shear strains and associated uncertainties for various types of tunnels and site profiles. However, the inter-linked platform of damage state - damage index - shear wave velocity - shear strain provides a novel approach for estimating the inelastic response of tunnels, and can be widely used in practice for seismic designs.

Traveling-wave Ti:LiNbO3 optical modulator capable of complete switching (완전 스위칭이 가능한 Ti:LiNbO3 진행파 광변조기)

  • 곽재곤;김경암;김영문;정은주;피중호;박권동;김창민
    • Korean Journal of Optics and Photonics
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    • v.14 no.5
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    • pp.545-554
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    • 2003
  • Design of the optical modulator composed of a three-waveguide coupler and CPW traveling-wave electrodes was carried out. Switching phenomena of three-waveguide couplers were analyzed by using the coupled mode theory, and the coupling-lengths of the devices were calculated by means of the FDM. CPW traveling-wave electrodes were analysed by the CMM and SOR simulation technique in order to find the conditions of phase-velocity and impedance matching. Traveling-wave modulators were fabricated on z-cut LiNbO$_3$ substrate. Ti was in-diffused in LiNbO$_3$ to make waveguides and Au electrodes were built on the waveguides by the electrolyte technique. The fabricated modulator chip was end-polished, pig-tailed and packaged in a brass mount with K-connector. The insertion loss and the switching voltage of the optical modulator were about 4㏈ and 19V, respectively. Network analyzer was used to obtain the S parameter and the corresponding RF response. From the measurement, parameters of the traveling-wave electrodes were extracted to be Z$_{c}$= 45 Ω, N$_{eff}$=2.20, and $\alpha$$_{0}$=0.055/cm√GHZ. The measured optical response R($\omega$) was compared with the theoretically estimated one, showing both responses agree well. The measurement results revealed that 3㏈ bandwidth turned out to be about 13 GHz.

Analytical Evaluations of the Retrofit Performances of Concrete Wall Structures Subjected to Blast Load (폭발하중을 받는 콘크리트 벽체 구조물의 보강 성능에 대한 해석적 분석)

  • Kim, Ho-Jin;Nam, Jin-Won;Kim, Sung-Bae;Kim, Jang-Ho;Byun, Keun-Joo
    • Journal of the Korea Concrete Institute
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    • v.19 no.2
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    • pp.241-250
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    • 2007
  • In case of retrofitting a concrete structure subjected to blast load by using retrofit materials such as FRP (fiber-reinforced polymer), appropriate ductility as well as raising stiffness must be obtained. But the previous approximate and simplified models, which have been generally used in the design and analysis of structures subjected to blast load, cannot accurately consider effects on retrofit materials. Problems on the accuracy and reliability of analysis results have also been pointed out. In addition, as the response of concrete and reinforcement on dynamic load is different from that on static load, it is not appropriate to use material properties defined in the previous static or quasi-static conditions to in calculating the response on the blast load. In this study, therefore, an accurate HFPB (high fidelity physics based) finite element analysis technique, which includes material models considering strength increase, and strain rate effect on blast load with very fast loading velocity, has been suggested using LS-DYNA, an explicit analysis program. Through the suggested analysis technique, the behavior on the blast load of retrofitted concrete walls using CFRP (carbon fiber-reinforced polymer) and GFRP (glass fiber-reinforced polymer) have been analyzed, and the retrofit capacity analysis has also been carried out by comparing with the analysis results of a wall without retrofit. As a result of the analysis, the retrofit capacity showing an approximate $26{\sim}28%$ reduction of maximum deflection, according to the retrofit, was confirmed, and it is judged ate suggested analysis technique can be effectively applicable in evaluating effectiveness of retrofit materials and techniques.

Ti:LiNbO3 three-waveguide type traveling-wave optical modulator; outer fed, anti-symmetrical Detuning (Ti:LiNbO3 세 도파로형 진행파 광변조기;바깥입사, 반대칭 Detuning)

  • 이우진;정은주;피중호;김창민
    • Korean Journal of Optics and Photonics
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    • v.15 no.4
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    • pp.375-384
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    • 2004
  • Switching phenomenon of a three-waveguide optical coupler was analyzed by using the coupled mode theory, and the coupling-length of the device was calculated by means of the FDM. CPW traveling-wave electrodes were designed by the CMM and SOR simulation techniques so as to satisfy the conditions of phase-velocity and impedance matching. Traveling-wave modulators were fabricated on a z-cut LiNbO$_3$ substrate. Ti was in-diffused in LiNbO$_3$ to make waveguides and Au electrodes were built on the waveguides by the electroplating technique. Insertion loss and switching voltage of the optical modulator were about 4 ㏈ and 15.6V. Network analyzer was used to obtain S parameters and corresponding RF response. From the measurement, parameters of the traveling-wave electrodes were extracted as such Z$_{c}$=39.2 $\Omega$, Neff=2.48, and a0=0.0665/cm((GHz) (1/2)). The measured optical response R(w) was compared with the theoretically estimated and both responses were shown to agree well. The measurement results revealed that the ㏈ bandwidth turned out to be about 13 GHz.

Application of ultrasonic energy to enhance capability of soil improving material (지반보강용 주입재의 성능향상을 위한 초음파 에너지의 활용)

  • Moon, Jun-ho;Xin, Zhenhua;Jeong, Ghang-bok;Kim, Young-uk
    • Journal of Korean Tunnelling and Underground Space Association
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    • v.19 no.4
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    • pp.567-576
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    • 2017
  • In a performance-based design, the structural safety is estimated from pre- defined damage states and corresponding damage indices. Both damage states and damage indices are well defined for above-ground structures, but very limited studies have been performed on underground structures. In this study, we define the damage states and damage indices of a cut-and-cover box tunnel which is one of typical structures used in metro systems, under a seismic excitation from a series of inelastic frame analyses. Three damage states are defined in terms of the number of plastic hinges that develop within the structure. The damage index is defined as the ratio of the elastic moment to the yield moment. Through use of the proposed index, the inelastic behavior and failure mechanism of box tunnels can be simulated and predicted through elastic analysis. In addition, the damage indices are linked to free-field shear strains. Because the free-field shear strain can be easily calculated from a 1D site response analysis, the proposed method can be readily used in practice. Further studies are needed to determine the range of shear strains and associated uncertainties for various types of tunnels and site profiles. However, the inter-linked platform of damage state - damage index - shear wave velocity - shear strain provides a novel approach for estimating the inelastic response of tunnels, and can be widely used in practice for seismic designs.

Formation and Evolution of Turbidity Maximum in thd Keum Estuary, West Coast of Korea (금강 하구에서의 최대혼탁수 형성 및 변화에 대한 연구)

  • 이창복;김태인
    • 한국해양학회지
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    • v.22 no.2
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    • pp.105-118
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    • 1987
  • A series of anchor stations were occupied along the Keum EAstuary during six different periods of tidal and fluvial regimes. The results clearly show that the formation and evolution of the turbidity maximum play an important role in the sedimentary processes in this environment. The turbidity maximum in the Keum Estuary is primarily related to the tidal range at the mouth and is caused by the resuspension of bottom sediments. In this estuary, the turbidity maximum is not a permanent feature and shows semidiurnal, fortnightly and seasonal variations. Repetition of deposition and resuspension of fine sediments occur in response to the variation in current velocity associated with semidiurnal tidal cycles. The core of turbidity maximum shifts landward or seaward accordion to the flood-ebb succession. The turbidity maximum also shows a fortnightly variation in response to the spring-neap cycles. Thus, the turbidity maximum degenerates during neap-tide and regenerates during spring-tide. The freshwater discharge is also an important factor in the formation and destruction of the turbidity maximum. The increase in freshwater discharge in rainy season can create an ebb-dominant current pattern which enhances the seaward transport of suspended sediments, resulting in the shortening of residence time of suspended materials in the estuary. Thus, under this high discharge condition, the turbidity maximum exists only during spring-tide and starts to disappear as the tidal amplitude decreases.

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