• Title/Summary/Keyword: Vascular

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Expression of Tumor Necrosis Factor (TNF)-z${\alpha}$ from Cells Undergoing Death by FADD

  • Kim, Koanhoi
    • Journal of Life Science
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    • v.12 no.2
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    • pp.57-60
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    • 2002
  • Apoptosis of vascular smooth muscle cell is observed in the vascular diseases such as atherosclerosis and restenosis. The death of vascular smooth muscle cells can be induced by cytokines and activation of Fas-pathways. It is widely accepted that apoptosis occurs without inflammation. There are, however, reports that apoptosis is not silent. Vascular smooth muscle cells dying by Fas-pathway secreted inflammatory cytokines including monocyte chemoattractant protein-1. This study have investigated whether apoptosis is associated with potent inflammatory cytokine tumor tumor necrosis factor (TNF)-${\alpha}$. The cells which undergo apoptosis by expressing FADD in the absence of tetracycline expressed and secreted TNF-${\alpha}$. When the level of TNF-${\alpha}$ transcript was investigated, dying smooth muscle cells exhibited transcriptional activation of TNF-${\alpha}$. The data indicate that dying vascular smooth muscle cells contribute to inflammation by expressing inflammatory cytokines. The present study suggests that apoptosis could not be silent in certain pathological situations.

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Cardamonin inhibits agonist-induced vascular contractility via Rho-kinase and MEK inhibition

  • Je, Hyun Dong;Jeong, Ji Hoon
    • The Korean Journal of Physiology and Pharmacology
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    • v.20 no.1
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    • pp.69-74
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    • 2016
  • The present study was undertaken to investigate the influence of cardamonin on vascular smooth muscle contractility and to determine the mechanism(s) involved. Denuded aortic rings from male rats were used and isometric contractions were recorded and combined with molecular experiments. Cardamonin significantly relaxed fluoride-, phenylephrine-, and phorbol ester-induced vascular contractions, suggesting that it has an anti-hypertensive effect on agonist-induced vascular contraction regardless of endothelial nitric oxide synthesis. Furthermore, cardamonin significantly inhibited the fluoride-induced increase in pMYPT1 level and phenylephrine-induced increase in pERK1/2 level, suggesting inhibition of Rho-kinase and MEK activity and subsequent phosphorylation of MYPT1 and ERK1/2. This study provides evidence that the relaxing effect of cardamonin on agonist-induced vascular contraction regardless of endothelial function involves inhibition of Rho-kinase and MEK activity.

Mediastinal Bronchogenic Cyst Misdiagnosed as Asthma and Dysphagia in a Child - One Case Report - (소아에서 천식과 연하곤란으로 진단된 종격동 기관지 낭종 - 1예 보고 -)

  • Lee, Seock-Yeol;Jeon, Cheol-Woo;Lee, Seung-Jin;Lee, Cheol-Sae;Lee, Kihl-Rho
    • Advances in pediatric surgery
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    • v.14 no.1
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    • pp.94-97
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    • 2008
  • A 19-month-old boy suffered from stridor and dysphagia. He was taking asthma medication for a few months, but symptoms did not improve. After admission, a chest CT showed a posterior mediastinal mass, which compressed the trachea and esophagus. The removed mass via open thoracotomy was a bronchogenic cyst on histopathology. Postoperatively, stridor and dysphagia disappeared. In case of persistent and refractory stridor or dysphagia in children, congenital lesions including bronchogenic cyst need to be ruled out.

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Early Ontogeny of Vascular Cambium in Cotyledonary Node of Seedlings in Pinus koraiensis S. et Z. (잣나무(Pinus koraiensis S. et Z.) 유식물의 자엽절에서 유관속 형성층의 초기 발생)

  • 홍성식
    • Journal of Plant Biology
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    • v.36 no.1
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    • pp.29-34
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    • 1993
  • Observation was made on early ontogeny of vascular cambium in the cotyledonary node of Pinus koraiensis seedling in order to clarify the cambial ontogeny of the node which was hardly elongated. In transverse view, the derivatives by the early periclinal divisions at the outer region of the procambial strands differentiated to protophloem with establishing a certain degree of radial seriations. Later, some cells in the central region of the procambial strands begin divide periclinally, eventually the cells, differentiate gradually to the vascular cambium. In tangential view, early procambium is consisted of homogeneous short cells with transverse end walls which are tansformed into the long cells and short cells gradually. The long cells continue intrusive growth and the short cells repeat transverse division. Finally, the long and short cells differentiated to cambial fusiform initials and ray initials respectively. In tangential section, the differentiation pattern of cambial initials resembles that of the stem of Ginkgo biloba. But in transverse view, the characteristics in the origin of vascular cambium of the cotyledonary node resembles that of root. The vascular cambium in cotyledonary node is completed after eleven prophylls were formed.

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Fast Template Matching for the Recognition of Hand Vascular Pattern (정맥패턴인식을 위한 고속 원형정합)

  • Choi, Kwang-Wook;Choi, Hwan-Soo;Pyo, Kwang-Soo
    • Proceedings of the KIEE Conference
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    • 2003.11c
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    • pp.532-535
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    • 2003
  • In this paper, we propose a new algorithm that can enhance the speed of template matching of hand vascular pattern person verification or recognition system. Various template matching algorithms have advantages in the matching accuracy, but most of the algorithms suffer from computational burden. To reduce the computational amount, with accuracy maintained, we propose following template matching scenario as follows. firstly, original hand vascular image is re-sampled in order to reduce spatial resolution. Secondly, reconstructed image is projected to vertical and horizontal direction, being converted to two one dimensional (1D) data. Thirdly, converted data is used to estimate spatial discrepancy between stored template image and target image. Finally, matching begins from where the estimated order is highest, and finishes when matching decision function is computed to be over certain threshold. We've applied the proposed algorithm to hand vascular pattern identification application for biometrics, and observed dramatic matching speed enhancement. This paper presents detailed explanation of the proposed algorithm and evaluation results.

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Treatment for Maior Vascular Injuries of Lower Lumbar Disc Surgery -2 Cases Report (요추 추간판 제거술중 발생한 대혈관 손상 수술 치험 -2례 보고-)

  • Kim, Seung-U;Hwang, Yun-Ho
    • Journal of Chest Surgery
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    • v.30 no.6
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    • pp.621-624
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    • 1997
  • Conventional surgery for lower lumbar disc herniation is a common practice and its vascular complications have been reported rarely. If the hypotension is severe or prolonged postoperatively, one should suspect vascular injury and perform urgent laparotomy. We experienced two cases of major vascular injuries following semi-laminectomy and discectomy.

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Video-Assisted Thoracoscopic Division of Vascular Rings

  • Lee, Jung Hee;Yang, Ji-Hyuk;Jun, Tae-Gook
    • Journal of Chest Surgery
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    • v.48 no.1
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    • pp.78-81
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    • 2015
  • This study reports our early experience with thoracoscopic division of vascular rings. Three patients were reviewed; their ages at surgery were 25 months, 4 years, and 57 years. All patients were suffering from complete vascular rings involving combinations of the right aortic arch, left ligamentum arteriosum, Kommerell's diverticulum, and retroesophageal left subclavian artery. The median surgical time was 180.5 minutes, and the patients showed immediate recovery. Three complications, namely chylothorax, transient supraventricular tachycardia, and left vocal cord palsy, were observed. Our early experience indicates that thoracoscopic division of a vascular ring may provide early recovery and could be a promising operative choice.

Vascular tumors of the liver: A brief review

  • Sujata Sarangi;Balamurugan Thirunavukkarasu;Sudeep Khera;Selvakumar B;Taruna Yadav
    • Annals of Hepato-Biliary-Pancreatic Surgery
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    • v.27 no.4
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    • pp.329-341
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    • 2023
  • Vascular tumors of the liver are mesenchymal lesions from endothelial cells. They range from common benign lesions such as haemangioma, intermediate tumors like Kaposi sarcoma, and perivascular epithelioid cell tumor to malignant tumors such as hepatic epithelioid hemangioendothelioma and hepatic angiosarcoma in adults. Pediatric vascular tumors of the liver also include benign, locally aggressive, borderline, and malignant masses with haemangiomas being the most common benign tumors and epithelioid hemangioendothelioma being an uncommon pediatric malignancy. The list of these lesions is completed by nodular regenerative hyperplasia, solitary fibrous tumour, and hepatic small vessel neoplasms (HSVN). Some of these tumors are uncommon and rare. This review article aimed to enumerate hepatic vascular tumors along with their imaging, histopathology, molecular findings for accurate diagnosis that can result in better management.

CT and MRI Findings of Low-Flow Mediastinal Vascular Malformation: A Case Report (종격동에 발생한 저혈류성 혈관 기형의 영상 소견: 증례 보고)

  • Hanlim Song;Mi Sook Lee;Soo-yeon Jeong
    • Journal of the Korean Society of Radiology
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    • v.85 no.1
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    • pp.204-209
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    • 2024
  • Mediastinal vascular malformations are rare and their diagnosis can be challenging. Imaging is vital for diagnosing mediastinal vascular malformations and can help avoid unnecessary invasive procedures. Herein, we report the detailed CT and MRI findings of a rare low-flow mediastinal vascular malformation in an asymptomatic 63-year-old male.

Vascular Augmentation in Renal Transplantation: Supercharging and Turbocharging

  • Jeong, Euicheol C.;Hwang, Seung Hwan;Eo, Su Rak
    • Archives of Plastic Surgery
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    • v.44 no.3
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    • pp.238-242
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    • 2017
  • The most common anatomic variant seen in donor kidneys for renal transplantation is the presence of multiple renal arteries, which can cause an increased risk of complications. Accessory renal arteries should be anastomosed to the proper source arteries to improve renal perfusion via the appropriate vascular reconstruction techniques. In microsurgery, 2 kinds of vascular augmentation methods, known as 'supercharging' and 'turbocharging,' have been introduced to ensure vascular perfusion in the transferred flap. Supercharging uses a distant source of the vessels, while turbocharging uses vascular sources within the same flap territory. These technical concepts can also be applied in renal transplantation, and in this report, we describe 2 patients who underwent procedures using supercharging and turbocharging. In one case, the ipsilateral deep inferior epigastric artery was transposed to the accessory renal artery (supercharging), and in the other case, the accessory renal artery was anastomosed to the corresponding main renal artery with a vascular graft (turbocharging). The transplanted kidneys showed good perfusion and proper function. No cases of renal failure, hypertension, rejection, or urologic complications were observed. These microsurgical techniques can be safely utilized for renal transplantation with donor kidneys that have multiple arteries with a lower complication rate and better outcome.