• Proceedings of the Computational Structural Engineering Institute Conference
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• 2006.04a
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• pp.557-564
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• 2006

Life-cycle performance and maintaining cost predictions are required for the effective management for bridges. In Korea, the importance of management of bridges has been recognized over the past two decades, resulting in the development of databases and various bridge management support tools by both government and private sectors. However, none of these tools has truly included the expected features of the bridge management system (EMS) for the next generation such as the quantification of the effects of maintenance interventions on bridge condition and safety. In this paper, a novel quantification process to simulate the life-cycle performance of steel box bridges has been developed. The process is based on the Response Surface method. Various performance-related variables aloe investigated to identify a set of significant design variables to construct the response surfaces.

• Computers and Concrete
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• v.9 no.3
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• pp.195-213
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• 2012

This paper presents the investigation of the stochastic responses of seismically isolated bridges subjected to spatially varying earthquake ground motions including incoherence, wave-passage and site-response effects. The incoherence effect is examined by considering Harichandran and Vanmarcke coherency model. The effect of the wave-passage is dealt with various wave velocities in the response analysis. Homogeneous firm, medium and soft soil conditions are selected for considering the site-response effect where the bridge supports are constructed. The ground motion is described by filtered white noise and applied to each support points. For seismic isolation of the bridge, single and double concave friction pendulum bearings are used. Due to presence of friction on the concave surfaces of the isolation systems, the equation of motion of is non-linear. The non-linear equation of motion is solved by using equivalent linearization technique of non-linear stochastic analyses. Solutions obtained from the stochastic analyses of non-isolated and isolated bridges to spatially varying earthquake ground motions compared with each other for the special cases of the ground motion model. It is concluded that friction pendulum systems having single and double concave surfaces have important effects on the stochastic responses of bridges to spatially varying earthquake ground motions.

• Journal of Sensor Science and Technology
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• v.20 no.6
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• pp.375-381
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• 2011

Ionic polymer-metal composite(IPMC) consists of an ion conductive membrane plated by metallic electrodes on both surfaces. When it bends, a voltage is generated between two electrodes. Since IPMC is flexible and thin, it can be easily mounted on the various surfaces of a body. The present study investigates a sensor system using IPMC to effectively detect the bending angles applied on IPMC sensor. The paper evaluates several R and C circuit models that describe the physical composition of IPMC and selects the best model for the detection of angles. The circuit models implemented with a charge model describe the relationship between input bending angles and output voltages. The identification of R and C values was performed by minimizing the error between the real output voltages and the simulated output voltages from the circuit models of IPMC sensor. Then the output signal of a sensor was fed into the inverse model of the identified model to reproduce the bending angles. In order to support the validation of the model, the output voltages from an arbitrary bending motion were also applied to the selected inverse model, which successfully reproduced the arbitrary bending motion.

• Journal of Mechanical Science and Technology
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• v.20 no.3
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• pp.366-375
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• 2006

In this paper, it is intended to introduce a method to solve multi-objective optimization problems and to evaluate its performance. In order to verify the performance of this method it is applied for a vertical roller mill for Portland cement. A design process is defined with the compromise decision support problem concept and a design process consists of two steps: the design of experiments and mathematical programming. In this process, a designer decides an object that the objective function is going to pursuit and a non-linear optimization is performed composing objective constraints with practical constraints. In this method, response surfaces are used to model objectives (stress, deflection and weight) and the optimization is performed for each of the objectives while handling the remaining ones as constraints. The response surfaces are constructed using orthogonal polynomials, and orthogonal array as design of experiment, with analysis of variance for variable selection. In addition, it establishes the relative influence of the design variables in the objectives variability. The constrained optimization problems are solved using sequential quadratic programming. From the results, it is found that the method in this paper is a very effective and powerful for the multi-objective optimization of various practical design problems. It provides, moreover, a reference of design to judge the amount of excess or shortage from the final object.

• Steel and Composite Structures
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• v.36 no.3
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• pp.355-367
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• 2020

The current work, present dynamic analysis of the FG-sandwich plate seated on elastic foundation with various kinds of support using refined shear deformation theory. The present analytical model is simplified which the unknowns number are reduced. The zero-shear stresses at the free surfaces of the FG-sandwich plate are ensured without introducing any correction factors. The four equations of motion are determined via Hamilton's principle and solved by Galerkin's approach for FG-sandwich plate with three kinds of the support. The proposed analytical model is verified by comparing the results with those obtained by other theories existing in the literature. The parametric studies are presented to detect the various parameters influencing the fundamental frequencies of the symmetric and non-symmetric FG-sandwich plate with various boundary conditions.

• Journal of the Korean Society of Physical Medicine
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• v.17 no.2
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• pp.75-82
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• 2022

PURPOSE: This study examined the correlation between the pulmonary function and respiratory muscle strengthening training on an unstable support surface and a stable support surface in stroke patients. METHODS: The study subjects were 22 stroke patients undergoing central nervous system developmental rehabilitation treatment. After excluding six dropouts, eight people in the experimental group and eight people in the control groups were classified by random sampling. Both groups performed central nervous system developmental rehabilitation therapy and were provided a 10-minute break. The experimental group was provided with an unstable support surface using Togu, and the control group was trained to strengthen the respiratory muscle in a stable support surface. Respiratory muscle strengthening training was conducted three times per week for 20 minutes. Before and after each group of experiments, a nonparametric test Wilcoxon signed rank test, and a Mann Whitney U-test analysis were used to analyze the variations between the two groups. All statistical significance levels (α) were set at 0.05. RESULTS: Both groups showed increases in the pulmonary function but showed significant differences only in the experimental group. There was a significant difference in the peak expiratory flow between the two groups. CONCLUSION: Central nervous system development rehabilitation treatment for patients with an impaired nervous system and respiratory muscle strengthening training on unstable support surfaces are effective in improving the pulmonary function of stroke patients. Therefore, they are expected to be applied to physical therapy programs to help various functional activities.

• Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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• 2005.11b
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• pp.148-151
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• 2005

Roughness of a road is an important parameter which not only indicates vehicle's vibration and noise, but it is also related to the contact force of the tire which is induced by tire's deformation and vibration. Since tire noise indeed comes from this deformation and vibration, the estimation of the force is the key factor fur the reduction of tire noise. Because of the difficulty of directly measuring the contact force, the indirect estimation is enforced from the vibration signature measured on the tire support. This study suggests the "inverse filtering" technique well known in modern digital signal processing, so as to reform the tire contact force from monitored vibration signals.

• Animal cells and systems
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• v.13 no.2
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• pp.113-118
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• 2009

Extracts derived from various medical mushrooms have been reported to have antitumor and immuno-modulatory properties. In order to investigate the antitumor activity of keumsa Linteusan, the water extract of Phellinus Iimteus, HT1080 cells, a human fibrosarcoma cell line, were treated with it and changes in cellular migration potential was tested in vitro. At a concentration range below 1,000 $\mu$g/mL, Linteusan blocked, in a dose dependent manner, the migration of cells through Matrigel as well as Boyden chamber without affecting the viability of the cells. Prolonged treatment of HT1080 cells with Linteusan suppressed TNFa induced production of matrix metalloproteinase (MMP)-9 as well as basal level expression of MMP-2. Linteusan also affected the adhesion of the cells to fibronectin-coated surfaces. The effect of Linteusan on cell signaling pathways was also tested. Linteusan specifically affected TNF-$\alpha$ induced phosphorylation of AKT in a dose-dependent manner, while phosphorylation levels of ERK remained unaffected. These data indicate that Linteusan blocks the migration of HT1080 cells by affecting various processes associated with cell migration such as the expression of matrix degradingenzymes,cell adhesion, and AKT-medicated cellular signaling pathways.

• Macromolecular Research
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• v.17 no.3
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• pp.192-196
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• 2009

Recently, the multi-screening of target materials has been made possible by the development of the surface plasmon resonance (SPR) imaging method. To adapt this method to biochemical analysis, the multi-patterning technology of protein microarrays is required. Among the different methods of fabricating protein microarrays, the microfluidic platform was selected due to its various advantages over other techniques. Microfluidic devices were designed and fabricated with polydimethylsiloxane (PDMS) by the replica molding method. These devices were designed to operate using only capillary force, without the need for additional flow control equipment. With these devices, multiple protein-patterned sensor surfaces were made, to support the two-dimensional detection of various protein-protein interactions with SPR. The fabrication technique of protein microarrays can be applied not only to SPR imaging, but also to other biochemical analyses.

• Journal of the Korean Crystal Growth and Crystal Technology
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• v.32 no.1
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• pp.33-39
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• 2022

As 3D printer-related patents expire and major technologies are disclosed, the price of 3D printers is dropping, creating an environment where you can easily find the product you want. In particular, the cheapest FDM (Fused Deposition Modeling) 3D printer is being used in various fields. The FDM method can be manufactured without collapsing of the shape only by attaching a support under certain conditions when outputting the shape. When printing a shape without a support, the irregular surface that occurs at a certain angle is a defect in the product, but it is considered that it can be used as another fun factor in terms of arts and crafts. In this paper, to obtain such an irregular surface, factors that can affect the output were controlled and only the output angle was tested as a displacement factor. As a result of the experiment, it was possible to obtain an irregular surface without the filament flowing down when printing at an angle of 62° to 70° from the vertical. Also, artificially irregular surfaces were applied to craft products.